MAPPFinder 2.0 Results for the Gene Ontology File: C:\Users\Katrina\Desktop\For_GenMAPP_Chlamydia_V4_20131204_KS.gex Table: CTrachomatis_EBtoRB_Rifampicin_20131204_DW-Criterion1-GO Database: C:\Users\Katrina\Downloads\Ct-Std_v2_KS_20131121.gdb colors:|EBtoRB Rif vs No Rif| 11/21/2013 ChlamydiaTrachomatisSerovarA Pvalues = true Calculation Summary: 471 probes met the [P value Rifampicin] < 0.05 criteria. 471 probes meeting the filter linked to a UniProt ID. 316 genes meeting the criterion linked to a GO term. 925 Probes in this dataset 925 Probes linked to a UniProt ID. 623 Genes linked to a GO term. The z score is based on an N of 623 and a R of 316 distinct genes in the GO. GOID GO Name GO Type Number Changed Local Number Measured Local Number in GO Local Percent Changed Local Percent Present Local Number Changed Number Measured Number in GO Percent Changed Percent Present Z Score PermuteP AdjustedP 0005198 structural molecule activity F 2 2 2 100 100 55 57 57 96.49123 100 7.246 0 0 0043232 intracellular non-membrane-bounded organelle C 0 0 0 0 0 55 58 58 94.82758 100 7.049 0 0 0043228 non-membrane-bounded organelle C 0 0 0 0 0 55 58 58 94.82758 100 7.049 0 0 0030529 ribonucleoprotein complex C 51 53 53 96.22642 100 52 54 54 96.2963 100 7.004 0 0 0005840 ribosome C 51 53 53 96.22642 100 51 53 53 96.22642 100 6.922 0 0 0003735 structural constituent of ribosome F 51 53 53 96.22642 100 51 53 53 96.22642 100 6.922 0 0 0043226 organelle C 0 0 0 0 0 55 59 59 93.22034 100 6.857 0 0 0043229 intracellular organelle C 0 0 0 0 0 55 59 59 93.22034 100 6.857 0 0 0006412 translation P 74 88 89 84.09091 98.8764 75 89 90 84.26966 98.88889 6.832 0 0 0044267 cellular protein metabolic process P 1 3 3 33.33333 100 90 114 115 78.94736 99.13043 6.663 0 0 0019538 protein metabolic process P 1 3 3 33.33333 100 100 135 136 74.07407 99.26471 6.127 0 0 0044444 cytoplasmic part C 0 0 0 0 0 59 70 70 84.28571 100 5.957 0 0 0019843 rRNA binding F 33 35 35 94.28571 100 33 35 35 94.28571 100 5.302 0 0 0005737 cytoplasm C 75 138 139 54.34783 99.28058 131 202 203 64.85149 99.50739 4.882 0 0 0010467 gene expression P 0 0 0 0 0 96 140 142 68.57143 98.59155 4.794 0 0 0009059 macromolecule biosynthetic process P 1 1 1 100 100 102 151 152 67.54967 99.3421 4.748 0 0 0034645 cellular macromolecule biosynthetic process P 0 0 0 0 0 101 150 151 67.33334 99.33775 4.666 0 0 0003723 RNA binding F 49 65 66 75.38461 98.48485 58 78 80 74.35897 97.5 4.461 0 0.001 0044424 intracellular part C 0 0 0 0 0 133 211 212 63.03318 99.52831 4.395 0 0.001 0005622 intracellular C 41 47 47 87.23404 100 133 213 214 62.44131 99.53271 4.214 0 0.003 0032991 macromolecular complex C 0 0 0 0 0 61 86 86 70.93023 100 4.034 0 0.004 0044464 cell part C 0 0 0 0 0 152 252 253 60.31746 99.60474 3.945 0 0.006 0005623 cell C 0 0 0 0 0 152 252 253 60.31746 99.60474 3.945 0 0.006 0009058 biosynthetic process P 12 14 14 85.71429 100 147 244 246 60.2459 99.18699 3.812 0 0.011 1901576 organic substance biosynthetic process P 0 0 0 0 0 143 237 239 60.33755 99.16318 3.758 0 0.013 0044249 cellular biosynthetic process P 0 0 0 0 0 141 234 236 60.25641 99.15254 3.689 0 0.013 0044260 cellular macromolecule metabolic process P 0 0 0 0 0 142 240 242 59.16667 99.17355 3.335 0 0.086 0016020 membrane C 29 74 74 39.18919 100 41 113 113 36.28318 100 -3.391 0 0.076 0044425 membrane part C 0 0 0 0 0 22 72 72 30.55556 100 -3.637 0 0.02 0043170 macromolecule metabolic process P 0 0 0 0 0 154 262 264 58.77863 99.24242 3.424 0.001 0.064 0044391 ribosomal subunit C 0 0 0 0 0 13 14 14 92.85714 100 3.187 0.001 0.146 0016021 integral to membrane C 19 66 66 28.78788 100 20 67 67 29.85075 100 -3.614 0.001 0.02 0003824 catalytic activity F 37 86 86 43.02325 100 185 413 415 44.79419 99.51807 -4.147 0.001 0.004 0044422 organelle part C 0 0 0 0 0 13 15 15 86.66666 100 2.816 0.002 0.474 0044446 intracellular organelle part C 0 0 0 0 0 13 15 15 86.66666 100 2.816 0.002 0.474 0004519 endonuclease activity F 1 9 9 11.11111 100 1 14 14 7.142857 100 -3.296 0.002 0.1 0031224 intrinsic to membrane C 0 0 0 0 0 21 68 68 30.88235 100 -3.464 0.002 0.05 0004536 deoxyribonuclease activity F 0 0 0 0 0 1 12 12 8.333333 100 -2.963 0.003 0.359 1901362 organic cyclic compound biosynthetic process P 0 0 0 0 0 26 73 74 35.61644 98.64865 -2.745 0.006 0.572 0004386 helicase activity F 1 12 12 8.333333 100 1 12 12 8.333333 100 -2.963 0.006 0.359 0071704 organic substance metabolic process P 0 0 0 0 0 220 400 403 55 99.25558 2.858 0.008 0.445 0003676 nucleic acid binding F 9 22 22 40.90909 100 89 148 150 60.13514 98.66666 2.621 0.008 0.696 0004520 endodeoxyribonuclease activity F 0 1 1 0 100 0 6 6 0 100 -2.495 0.008 0.874 0044238 primary metabolic process P 0 0 0 0 0 207 374 377 55.3476 99.20425 2.828 0.009 0.467 0051716 cellular response to stimulus P 0 0 0 0 0 8 29 29 27.58621 100 -2.55 0.009 0.784 0006457 protein folding P 10 10 10 100 100 10 11 11 90.90909 100 2.688 0.011 0.639 0003700 sequence-specific DNA binding transcription factor activity F 0 6 6 0 100 0 6 6 0 100 -2.495 0.011 0.874 0001071 nucleic acid binding transcription factor activity F 0 0 0 0 0 0 6 6 0 100 -2.495 0.011 0.874 0019438 aromatic compound biosynthetic process P 0 0 0 0 0 24 67 68 35.8209 98.52941 -2.58 0.011 0.754 0006281 DNA repair P 6 23 23 26.08696 100 6 23 23 26.08696 100 -2.406 0.013 0.925 0006974 cellular response to DNA damage stimulus P 5 19 19 26.31579 100 6 23 23 26.08696 100 -2.406 0.013 0.925 0043168 anion binding F 0 0 0 0 0 72 170 170 42.35294 100 -2.558 0.013 0.777 1901360 organic cyclic compound metabolic process P 0 0 0 0 0 93 214 216 43.45794 99.07407 -2.621 0.014 0.695 0044237 cellular metabolic process P 1 1 1 100 100 211 386 389 54.66321 99.22879 2.509 0.015 0.8 0043234 protein complex C 0 0 0 0 0 9 31 31 29.03226 100 -2.476 0.015 0.874 0033554 cellular response to stress P 0 1 1 0 100 7 25 25 28 100 -2.318 0.018 0.943 0006725 cellular aromatic compound metabolic process P 0 0 0 0 0 91 208 210 43.75 99.04762 -2.462 0.02 0.891 0005524 ATP binding F 53 130 130 40.76923 100 53 130 130 40.76923 100 -2.55 0.02 0.784 0032559 adenyl ribonucleotide binding F 0 0 0 0 0 53 130 130 40.76923 100 -2.55 0.02 0.784 0034641 cellular nitrogen compound metabolic process P 0 0 0 0 0 91 208 210 43.75 99.04762 -2.462 0.021 0.891 0017111 nucleoside-triphosphatase activity F 15 33 33 45.45454 100 24 65 65 36.92308 100 -2.349 0.022 0.94 0015934 large ribosomal subunit C 6 6 6 100 100 6 6 6 100 100 2.424 0.024 0.922 0016740 transferase activity F 49 118 118 41.52542 100 54 130 130 41.53846 100 -2.353 0.024 0.94 0018130 heterocycle biosynthetic process P 0 0 0 0 0 25 68 69 36.76471 98.55073 -2.437 0.024 0.896 0030554 adenyl nucleotide binding F 2 5 5 40 100 56 136 136 41.17647 100 -2.516 0.024 0.799 1990204 oxidoreductase complex C 0 0 0 0 0 0 6 6 0 100 -2.495 0.026 0.874 0090305 nucleic acid phosphodiester bond hydrolysis P 4 16 16 25 100 4 17 17 23.52941 100 -2.272 0.027 0.98 0046483 heterocycle metabolic process P 0 0 0 0 0 92 209 211 44.01914 99.05213 -2.376 0.027 0.939 0044271 cellular nitrogen compound biosynthetic process P 0 0 0 0 0 26 69 70 37.68116 98.57143 -2.296 0.028 0.957 0007154 cell communication P 0 0 0 0 0 2 11 11 18.18182 100 -2.176 0.033 0.996 0035639 purine ribonucleoside triphosphate binding F 0 0 0 0 0 61 143 143 42.65734 100 -2.196 0.033 0.994 0001883 purine nucleoside binding F 0 0 0 0 0 61 143 143 42.65734 100 -2.196 0.033 0.994 0032555 purine ribonucleotide binding F 0 0 0 0 0 61 143 143 42.65734 100 -2.196 0.033 0.994 0032550 purine ribonucleoside binding F 0 0 0 0 0 61 143 143 42.65734 100 -2.196 0.033 0.994 0036094 small molecule binding F 0 0 0 0 0 79 181 181 43.64641 100 -2.259 0.033 0.98 0004518 nuclease activity F 4 17 17 23.52941 100 10 31 31 32.25806 100 -2.108 0.034 0.998 0006807 nitrogen compound metabolic process P 0 1 1 0 100 106 236 238 44.91525 99.15966 -2.262 0.034 0.98 0043167 ion binding F 0 0 0 0 0 100 223 223 44.84305 100 -2.19 0.035 0.994 0016787 hydrolase activity F 38 91 91 41.75824 100 70 160 160 43.75 100 -2.045 0.039 1 0001882 nucleoside binding F 0 0 0 0 0 62 144 144 43.05556 100 -2.097 0.039 0.998 0032549 ribonucleoside binding F 1 1 1 100 100 62 144 144 43.05556 100 -2.097 0.039 0.998 0017076 purine nucleotide binding F 1 1 1 100 100 64 149 149 42.95302 100 -2.173 0.039 0.997 0032553 ribonucleotide binding F 0 0 0 0 0 63 146 146 43.15068 100 -2.09 0.042 0.999 0008152 metabolic process P 23 59 59 38.98305 100 249 470 473 52.97872 99.36575 1.973 0.044 1 0016614 oxidoreductase activity, acting on CH-OH group of donors F 0 4 4 0 100 3 13 13 23.07692 100 -2.013 0.045 1 0051536 iron-sulfur cluster binding F 3 12 12 25 100 3 13 13 23.07692 100 -2.013 0.046 1 0051540 metal cluster binding F 0 0 0 0 0 3 13 13 23.07692 100 -2.013 0.046 1 0016462 pyrophosphatase activity F 0 0 0 0 0 26 67 67 38.80597 100 -2.064 0.046 1 0016818 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides F 0 0 0 0 0 26 67 67 38.80597 100 -2.064 0.046 1 0016817 hydrolase activity, acting on acid anhydrides F 0 0 0 0 0 26 67 67 38.80597 100 -2.064 0.046 1 0097367 carbohydrate derivative binding F 0 0 0 0 0 64 147 147 43.53741 100 -1.992 0.048 1 1901681 sulfur compound binding F 0 0 0 0 0 0 4 4 0 100 -2.034 0.051 1 0015935 small ribosomal subunit C 7 8 8 87.5 100 7 8 8 87.5 100 2.092 0.055 0.999 1901265 nucleoside phosphate binding F 0 0 0 0 0 78 176 176 44.31818 100 -2.005 0.056 1 0000166 nucleotide binding F 56 126 126 44.44444 100 78 176 176 44.31818 100 -2.005 0.056 1 0006259 DNA metabolic process P 5 5 5 100 100 19 51 51 37.2549 100 -2.006 0.056 1 0046417 chorismate metabolic process P 0 0 0 0 0 0 4 4 0 100 -2.034 0.056 1 0009423 chorismate biosynthetic process P 0 4 4 0 100 0 4 4 0 100 -2.034 0.056 1 0008854 exodeoxyribonuclease V activity F 0 4 4 0 100 0 4 4 0 100 -2.034 0.057 1 0051082 unfolded protein binding F 5 5 5 100 100 5 5 5 100 100 2.211 0.059 0.993 0031668 cellular response to extracellular stimulus P 0 0 0 0 0 1 7 7 14.28571 100 -1.938 0.061 1 0009432 SOS response P 1 7 7 14.28571 100 1 7 7 14.28571 100 -1.938 0.061 1 0071496 cellular response to external stimulus P 0 0 0 0 0 1 7 7 14.28571 100 -1.938 0.061 1 0009605 response to external stimulus P 0 0 0 0 0 1 7 7 14.28571 100 -1.938 0.061 1 0009991 response to extracellular stimulus P 0 0 0 0 0 1 7 7 14.28571 100 -1.938 0.061 1 0016893 endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5’-phosphomonoesters F 0 0 0 0 0 1 7 7 14.28571 100 -1.938 0.065 1 0000104 succinate dehydrogenase activity F 0 4 4 0 100 0 4 4 0 100 -2.034 0.066 1 0043492 ATPase activity, coupled to movement of substances F 0 0 0 0 0 2 10 10 20 100 -1.957 0.069 1 0016820 hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances F 0 1 1 0 100 2 10 10 20 100 -1.957 0.069 1 0042626 ATPase activity, coupled to transmembrane movement of substances F 1 5 5 20 100 2 10 10 20 100 -1.957 0.069 1 0016072 rRNA metabolic process P 0 0 0 0 0 1 7 7 14.28571 100 -1.938 0.071 1 0006364 rRNA processing P 0 6 6 0 100 1 7 7 14.28571 100 -1.938 0.071 1 0009987 cellular process P 0 2 2 0 100 229 430 434 53.25581 99.07834 1.886 0.077 1 0006139 nucleobase-containing compound metabolic process P 2 4 4 50 100 84 186 187 45.16129 99.46524 -1.81 0.082 1 0000049 tRNA binding F 10 13 13 76.92308 100 10 13 13 76.92308 100 1.908 0.09 1 0032508 DNA duplex unwinding P 0 3 3 0 100 0 3 3 0 100 -1.76 0.097 1 0032392 DNA geometric change P 0 0 0 0 0 0 3 3 0 100 -1.76 0.097 1 0006099 tricarboxylic acid cycle P 1 6 6 16.66667 100 1 6 6 16.66667 100 -1.675 0.105 1 0009060 aerobic respiration P 0 0 0 0 0 1 6 6 16.66667 100 -1.675 0.105 1 0051234 establishment of localization P 0 0 0 0 0 37 87 88 42.52874 98.86364 -1.647 0.106 1 0051179 localization P 0 0 0 0 0 37 87 88 42.52874 98.86364 -1.647 0.106 1 0006810 transport P 20 54 54 37.03704 100 37 87 88 42.52874 98.86364 -1.647 0.106 1 0033014 tetrapyrrole biosynthetic process P 1 5 5 20 100 2 9 9 22.22222 100 -1.721 0.109 1 0033013 tetrapyrrole metabolic process P 0 0 0 0 0 2 9 9 22.22222 100 -1.721 0.109 1 0000096 sulfur amino acid metabolic process P 0 0 0 0 0 0 3 3 0 100 -1.76 0.113 1 0006289 nucleotide-excision repair P 0 3 3 0 100 0 3 3 0 100 -1.76 0.114 1 0009381 excinuclease ABC activity F 0 3 3 0 100 0 3 3 0 100 -1.76 0.114 1 0008170 N-methyltransferase activity F 0 0 0 0 0 0 3 3 0 100 -1.76 0.115 1 0006767 water-soluble vitamin metabolic process P 0 0 0 0 0 1 6 6 16.66667 100 -1.675 0.117 1 0009110 vitamin biosynthetic process P 0 0 0 0 0 1 6 6 16.66667 100 -1.675 0.117 1 0006766 vitamin metabolic process P 0 0 0 0 0 1 6 6 16.66667 100 -1.675 0.117 1 0042364 water-soluble vitamin biosynthetic process P 0 0 0 0 0 1 6 6 16.66667 100 -1.675 0.117 1 0090304 nucleic acid metabolic process P 0 0 0 0 0 57 129 130 44.18605 99.23077 -1.666 0.118 1 0015297 antiporter activity F 0 1 1 0 100 0 3 3 0 100 -1.76 0.118 1 0004529 exodeoxyribonuclease activity F 0 0 0 0 0 1 6 6 16.66667 100 -1.675 0.12 1 0016895 exodeoxyribonuclease activity, producing 5’-phosphomonoesters F 0 0 0 0 0 1 6 6 16.66667 100 -1.675 0.12 1 0016853 isomerase activity F 17 25 26 68 96.15385 18 27 28 66.66666 96.42857 1.693 0.122 1 0051539 4 iron, 4 sulfur cluster binding F 1 6 6 16.66667 100 1 6 6 16.66667 100 -1.675 0.122 1 0000990 core RNA polymerase binding transcription factor activity F 0 0 0 0 0 0 3 3 0 100 -1.76 0.122 1 0000988 protein binding transcription factor activity F 0 0 0 0 0 0 3 3 0 100 -1.76 0.122 1 0000996 core DNA-dependent RNA polymerase binding promoter specificity activity F 0 0 0 0 0 0 3 3 0 100 -1.76 0.122 1 0006352 DNA-dependent transcription, initiation P 0 3 3 0 100 0 3 3 0 100 -1.76 0.122 1 0016775 phosphotransferase activity, nitrogenous group as acceptor F 0 1 1 0 100 0 3 3 0 100 -1.76 0.122 1 0016987 sigma factor activity F 0 3 3 0 100 0 3 3 0 100 -1.76 0.122 1 0009055 electron carrier activity F 0 3 3 0 100 0 3 3 0 100 -1.76 0.124 1 0003678 DNA helicase activity F 0 3 3 0 100 1 6 6 16.66667 100 -1.675 0.125 1 0005829 cytosol C 4 4 4 100 100 6 7 7 85.71429 100 1.861 0.127 1 0042623 ATPase activity, coupled F 0 0 0 0 0 8 23 23 34.78261 100 -1.557 0.128 1 0004521 endoribonuclease activity F 0 1 1 0 100 1 6 6 16.66667 100 -1.675 0.129 1 0006284 base-excision repair P 0 3 3 0 100 0 3 3 0 100 -1.76 0.13 1 0003677 DNA binding F 25 58 58 43.10345 100 25 61 61 40.98361 100 -1.601 0.131 1 0016887 ATPase activity F 8 19 19 42.10526 100 15 39 39 38.46154 100 -1.581 0.137 1 0006355 regulation of transcription, DNA-dependent P 6 17 17 35.29412 100 6 18 18 33.33333 100 -1.496 0.142 1 0051252 regulation of RNA metabolic process P 0 0 0 0 0 6 18 18 33.33333 100 -1.496 0.142 1 2001141 regulation of RNA biosynthetic process P 0 0 0 0 0 6 18 18 33.33333 100 -1.496 0.142 1 0016491 oxidoreductase activity F 22 51 51 43.13726 100 23 57 57 40.35088 100 -1.642 0.145 1 0072330 monocarboxylic acid biosynthetic process P 0 0 0 0 0 9 12 12 75 100 1.697 0.146 1 0006633 fatty acid biosynthetic process P 8 11 11 72.72727 100 9 12 12 75 100 1.697 0.146 1 0006631 fatty acid metabolic process P 3 5 5 60 100 9 12 12 75 100 1.697 0.146 1 0016765 transferase activity, transferring alkyl or aryl (other than methyl) groups F 0 5 5 0 100 4 13 13 30.76923 100 -1.453 0.151 1 0019219 regulation of nucleobase-containing compound metabolic process P 0 0 0 0 0 7 20 20 35 100 -1.428 0.158 1 0051171 regulation of nitrogen compound metabolic process P 0 0 0 0 0 7 20 20 35 100 -1.428 0.158 1 0051188 cofactor biosynthetic process P 0 2 2 0 100 7 20 20 35 100 -1.428 0.158 1 0045333 cellular respiration P 0 0 0 0 0 2 8 8 25 100 -1.463 0.158 1 0005515 protein binding F 0 0 0 0 0 9 12 12 75 100 1.697 0.159 1 0009073 aromatic amino acid family biosynthetic process P 2 8 8 25 100 2 8 9 25 88.88889 -1.463 0.159 1 0009072 aromatic amino acid family metabolic process P 0 0 0 0 0 2 8 9 25 88.88889 -1.463 0.159 1 0034654 nucleobase-containing compound biosynthetic process P 0 0 0 0 0 19 47 47 40.42553 100 -1.467 0.167 1 0022804 active transmembrane transporter activity F 0 0 0 0 0 9 25 25 36 100 -1.502 0.17 1 0055114 oxidation-reduction process P 22 56 56 39.28571 100 28 67 67 41.79105 100 -1.547 0.174 1 0006779 porphyrin-containing compound biosynthetic process P 2 8 8 25 100 2 8 8 25 100 -1.463 0.18 1 0006778 porphyrin-containing compound metabolic process P 0 0 0 0 0 2 8 8 25 100 -1.463 0.18 1 0016788 hydrolase activity, acting on ester bonds F 1 1 1 100 100 17 42 42 40.47619 100 -1.374 0.188 1 0016772 transferase activity, transferring phosphorus-containing groups F 1 7 7 14.28571 100 21 51 51 41.17647 100 -1.422 0.191 1 0043565 sequence-specific DNA binding F 1 5 5 20 100 1 5 5 20 100 -1.379 0.193 1 0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor F 1 4 4 25 100 3 10 10 30 100 -1.32 0.197 1 0042727 flavin-containing compound biosynthetic process P 0 0 0 0 0 1 5 5 20 100 -1.379 0.197 1 0006771 riboflavin metabolic process P 0 0 0 0 0 1 5 5 20 100 -1.379 0.197 1 0042726 flavin-containing compound metabolic process P 0 0 0 0 0 1 5 5 20 100 -1.379 0.197 1 0009231 riboflavin biosynthetic process P 1 5 5 20 100 1 5 5 20 100 -1.379 0.197 1 0016796 exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5’-phosphomonoesters F 0 0 0 0 0 2 8 8 25 100 -1.463 0.197 1 0005575 cellular_component C 0 0 0 0 0 175 328 329 53.35366 99.69604 1.384 0.198 1 0008238 exopeptidase activity F 0 0 0 0 0 1 5 5 20 100 -1.379 0.201 1 0030145 manganese ion binding F 5 6 6 83.33334 100 5 6 6 83.33334 100 1.604 0.205 1 0006790 sulfur compound metabolic process P 0 0 0 0 0 1 5 5 20 100 -1.379 0.212 1 0046451 diaminopimelate metabolic process P 0 0 0 0 0 5 6 6 83.33334 100 1.604 0.213 1 0009085 lysine biosynthetic process P 3 3 3 100 100 5 6 6 83.33334 100 1.604 0.213 1 0006553 lysine metabolic process P 0 0 0 0 0 5 6 6 83.33334 100 1.604 0.213 1 0009089 lysine biosynthetic process via diaminopimelate P 5 6 6 83.33334 100 5 6 6 83.33334 100 1.604 0.213 1 0000097 sulfur amino acid biosynthetic process P 0 0 0 0 0 0 2 2 0 100 -1.436 0.214 1 0009086 methionine biosynthetic process P 0 2 2 0 100 0 2 2 0 100 -1.436 0.214 1 0006555 methionine metabolic process P 0 0 0 0 0 0 2 2 0 100 -1.436 0.214 1 0016301 kinase activity F 8 22 22 36.36364 100 9 24 24 37.5 100 -1.32 0.216 1 0052689 carboxylic ester hydrolase activity F 0 0 0 0 0 5 6 6 83.33334 100 1.604 0.218 1 0004652 polynucleotide adenylyltransferase activity F 0 2 2 0 100 0 2 2 0 100 -1.436 0.218 1 0004810 tRNA adenylyltransferase activity F 0 2 2 0 100 0 2 2 0 100 -1.436 0.218 1 0009126 purine nucleoside monophosphate metabolic process P 0 0 0 0 0 9 24 24 37.5 100 -1.32 0.219 1 0009161 ribonucleoside monophosphate metabolic process P 0 0 0 0 0 9 24 24 37.5 100 -1.32 0.219 1 0009167 purine ribonucleoside monophosphate metabolic process P 0 0 0 0 0 9 24 24 37.5 100 -1.32 0.219 1 1901566 organonitrogen compound biosynthetic process P 0 0 0 0 0 27 63 64 42.85714 98.4375 -1.316 0.223 1 0019201 nucleotide kinase activity F 0 1 1 0 100 1 5 5 20 100 -1.379 0.224 1 0050896 response to stimulus P 0 0 0 0 0 15 37 37 40.54054 100 -1.276 0.227 1 0016891 endoribonuclease activity, producing 5’-phosphomonoesters F 0 1 1 0 100 1 5 5 20 100 -1.379 0.228 1 0004814 arginine-tRNA ligase activity F 0 2 2 0 100 0 2 2 0 100 -1.436 0.228 1 0031123 RNA 3’-end processing P 0 0 0 0 0 0 2 2 0 100 -1.436 0.228 1 0006420 arginyl-tRNA aminoacylation P 0 2 2 0 100 0 2 2 0 100 -1.436 0.228 1 0006793 phosphorus metabolic process P 0 0 0 0 0 44 98 98 44.89796 100 -1.255 0.229 1 0006397 mRNA processing P 0 1 1 0 100 0 2 2 0 100 -1.436 0.229 1 0033293 monocarboxylic acid binding F 0 0 0 0 0 0 2 2 0 100 -1.436 0.23 1 0031406 carboxylic acid binding F 0 0 0 0 0 0 2 2 0 100 -1.436 0.23 1 0008658 penicillin binding F 0 2 2 0 100 0 2 2 0 100 -1.436 0.23 1 0033218 amide binding F 0 0 0 0 0 0 2 2 0 100 -1.436 0.23 1 0043177 organic acid binding F 0 0 0 0 0 0 2 2 0 100 -1.436 0.23 1 0030983 mismatched DNA binding F 0 2 2 0 100 0 2 2 0 100 -1.436 0.231 1 0006298 mismatch repair P 0 2 2 0 100 0 2 2 0 100 -1.436 0.231 1 0032300 mismatch repair complex C 0 2 2 0 100 0 2 2 0 100 -1.436 0.231 1 0003690 double-stranded DNA binding F 0 0 0 0 0 0 2 2 0 100 -1.436 0.231 1 0015605 organophosphate ester transmembrane transporter activity F 0 0 0 0 0 0 2 2 0 100 -1.436 0.234 1 0009380 excinuclease repair complex C 0 2 2 0 100 0 2 2 0 100 -1.436 0.234 1 0008649 rRNA methyltransferase activity F 0 1 1 0 100 0 2 2 0 100 -1.436 0.234 1 0015216 purine nucleotide transmembrane transporter activity F 0 0 0 0 0 0 2 2 0 100 -1.436 0.234 1 0015217 ADP transmembrane transporter activity F 0 0 0 0 0 0 2 2 0 100 -1.436 0.234 1 0015211 purine nucleoside transmembrane transporter activity F 0 0 0 0 0 0 2 2 0 100 -1.436 0.234 1 0009244 lipopolysaccharide core region biosynthetic process P 0 2 2 0 100 0 2 2 0 100 -1.436 0.234 1 0005337 nucleoside transmembrane transporter activity F 0 0 0 0 0 0 2 2 0 100 -1.436 0.234 1 1901505 carbohydrate derivative transporter activity F 0 0 0 0 0 0 2 2 0 100 -1.436 0.234 1 0005347 ATP transmembrane transporter activity F 0 0 0 0 0 0 2 2 0 100 -1.436 0.234 1 0005346 purine ribonucleotide transmembrane transporter activity F 0 0 0 0 0 0 2 2 0 100 -1.436 0.234 1 0015932 nucleobase-containing compound transmembrane transporter activity F 0 0 0 0 0 0 2 2 0 100 -1.436 0.234 1 0015215 nucleotide transmembrane transporter activity F 0 0 0 0 0 0 2 2 0 100 -1.436 0.234 1 0046401 lipopolysaccharide core region metabolic process P 0 0 0 0 0 0 2 2 0 100 -1.436 0.234 1 0005471 ATP:ADP antiporter activity F 0 2 2 0 100 0 2 2 0 100 -1.436 0.234 1 0000295 adenine nucleotide transmembrane transporter activity F 0 0 0 0 0 0 2 2 0 100 -1.436 0.234 1 0015301 anion:anion antiporter activity F 0 0 0 0 0 0 2 2 0 100 -1.436 0.234 1 0019842 vitamin binding F 0 0 0 0 0 0 2 2 0 100 -1.436 0.235 1 0030976 thiamine pyrophosphate binding F 0 2 2 0 100 0 2 2 0 100 -1.436 0.235 1 0005576 extracellular region C 3 3 3 100 100 3 3 3 100 100 1.71 0.236 1 0042158 lipoprotein biosynthetic process P 0 2 2 0 100 0 2 2 0 100 -1.436 0.236 1 0042157 lipoprotein metabolic process P 0 0 0 0 0 0 2 2 0 100 -1.436 0.236 1 0032259 methylation P 6 17 17 35.29412 100 6 17 17 35.29412 100 -1.289 0.237 1 0016888 endodeoxyribonuclease activity, producing 5’-phosphomonoesters F 0 1 1 0 100 0 2 2 0 100 -1.436 0.237 1 0045239 tricarboxylic acid cycle enzyme complex C 0 1 1 0 100 0 2 2 0 100 -1.436 0.239 1 0016805 dipeptidase activity F 0 2 2 0 100 0 2 2 0 100 -1.436 0.24 1 0009378 four-way junction helicase activity F 0 2 2 0 100 0 2 2 0 100 -1.436 0.24 1 0009063 cellular amino acid catabolic process P 0 0 0 0 0 0 2 2 0 100 -1.436 0.241 1 1901606 alpha-amino acid catabolic process P 0 0 0 0 0 0 2 2 0 100 -1.436 0.241 1 0016054 organic acid catabolic process P 0 0 0 0 0 0 2 2 0 100 -1.436 0.241 1 0044712 single-organism catabolic process P 0 0 0 0 0 0 2 2 0 100 -1.436 0.241 1 0044282 small molecule catabolic process P 0 0 0 0 0 0 2 2 0 100 -1.436 0.241 1 0046395 carboxylic acid catabolic process P 0 0 0 0 0 0 2 2 0 100 -1.436 0.241 1 0019239 deaminase activity F 0 0 0 0 0 0 2 2 0 100 -1.436 0.242 1 0019276 UDP-N-acetylgalactosamine metabolic process P 0 0 0 0 0 0 2 2 0 100 -1.436 0.243 1 0019277 UDP-N-acetylgalactosamine biosynthetic process P 0 2 2 0 100 0 2 2 0 100 -1.436 0.243 1 0008194 UDP-glycosyltransferase activity F 0 0 0 0 0 0 2 2 0 100 -1.436 0.245 1 0016878 acid-thiol ligase activity F 0 0 0 0 0 0 2 2 0 100 -1.436 0.246 1 0004775 succinate-CoA ligase (ADP-forming) activity F 0 2 2 0 100 0 2 2 0 100 -1.436 0.246 1 0016877 ligase activity, forming carbon-sulfur bonds F 0 0 0 0 0 0 2 2 0 100 -1.436 0.246 1 0004774 succinate-CoA ligase activity F 0 0 0 0 0 0 2 2 0 100 -1.436 0.246 1 0033178 proton-transporting two-sector ATPase complex, catalytic domain C 0 2 2 0 100 0 2 2 0 100 -1.436 0.246 1 0016405 CoA-ligase activity F 0 0 0 0 0 0 2 2 0 100 -1.436 0.246 1 0016811 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides F 0 0 0 0 0 3 3 3 100 100 1.71 0.247 1 0019637 organophosphate metabolic process P 0 0 0 0 0 37 83 83 44.57831 100 -1.202 0.247 1 0005402 cation:sugar symporter activity F 0 0 0 0 0 0 2 2 0 100 -1.436 0.247 1 0051119 sugar transmembrane transporter activity F 0 0 0 0 0 0 2 2 0 100 -1.436 0.247 1 0015295 solute:hydrogen symporter activity F 0 0 0 0 0 0 2 2 0 100 -1.436 0.247 1 0008643 carbohydrate transport P 0 0 0 0 0 0 2 2 0 100 -1.436 0.247 1 0009401 phosphoenolpyruvate-dependent sugar phosphotransferase system P 0 2 2 0 100 0 2 2 0 100 -1.436 0.247 1 0005351 sugar:hydrogen symporter activity F 0 2 2 0 100 0 2 2 0 100 -1.436 0.247 1 0019104 DNA N-glycosylase activity F 0 1 1 0 100 0 2 2 0 100 -1.436 0.247 1 0006241 CTP biosynthetic process P 1 1 1 100 100 3 3 3 100 100 1.71 0.25 1 0009208 pyrimidine ribonucleoside triphosphate metabolic process P 0 0 0 0 0 3 3 3 100 100 1.71 0.25 1 0046036 CTP metabolic process P 0 0 0 0 0 3 3 3 100 100 1.71 0.25 1 0006213 pyrimidine nucleoside metabolic process P 0 0 0 0 0 3 3 3 100 100 1.71 0.25 1 0046132 pyrimidine ribonucleoside biosynthetic process P 0 0 0 0 0 3 3 3 100 100 1.71 0.25 1 0009209 pyrimidine ribonucleoside triphosphate biosynthetic process P 0 0 0 0 0 3 3 3 100 100 1.71 0.25 1 0046134 pyrimidine nucleoside biosynthetic process P 0 0 0 0 0 3 3 3 100 100 1.71 0.25 1 0046131 pyrimidine ribonucleoside metabolic process P 0 0 0 0 0 3 3 3 100 100 1.71 0.25 1 0008444 CDP-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase activity F 0 2 2 0 100 0 2 2 0 100 -1.436 0.254 1 0016832 aldehyde-lyase activity F 1 1 1 100 100 3 3 3 100 100 1.71 0.255 1 0004739 pyruvate dehydrogenase (acetyl-transferring) activity F 0 2 2 0 100 0 2 2 0 100 -1.436 0.256 1 0004738 pyruvate dehydrogenase activity F 0 0 0 0 0 0 2 2 0 100 -1.436 0.256 1 0009186 deoxyribonucleoside diphosphate metabolic process P 0 1 1 0 100 0 2 2 0 100 -1.436 0.259 1 0016209 antioxidant activity F 1 1 1 100 100 3 3 3 100 100 1.71 0.26 1 0044763 single-organism cellular process P 0 0 0 0 0 47 103 105 45.63107 98.09524 -1.13 0.26 1 0044699 single-organism process P 0 0 0 0 0 58 126 128 46.03175 98.4375 -1.178 0.262 1 0051537 2 iron, 2 sulfur cluster binding F 0 2 2 0 100 0 2 2 0 100 -1.436 0.262 1 0032774 RNA biosynthetic process P 0 0 0 0 0 9 23 23 39.13044 100 -1.132 0.263 1 0043952 protein transport by the Sec complex P 3 3 3 100 100 3 3 3 100 100 1.71 0.267 1 0015291 secondary active transmembrane transporter activity F 0 0 0 0 0 4 12 12 33.33333 100 -1.216 0.267 1 0016838 carbon-oxygen lyase activity, acting on phosphates F 0 0 0 0 0 0 2 2 0 100 -1.436 0.269 1 0004748 ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor F 0 2 2 0 100 0 2 2 0 100 -1.436 0.271 1 0005971 ribonucleoside-diphosphate reductase complex C 0 2 2 0 100 0 2 2 0 100 -1.436 0.271 1 0016728 oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor F 0 0 0 0 0 0 2 2 0 100 -1.436 0.271 1 0009212 pyrimidine deoxyribonucleoside triphosphate biosynthetic process P 0 0 0 0 0 0 2 2 0 100 -1.436 0.273 1 0009202 deoxyribonucleoside triphosphate biosynthetic process P 0 0 0 0 0 0 2 2 0 100 -1.436 0.273 1 0015405 P-P-bond-hydrolysis-driven transmembrane transporter activity F 0 0 0 0 0 4 12 12 33.33333 100 -1.216 0.274 1 0015399 primary active transmembrane transporter activity F 0 0 0 0 0 4 12 12 33.33333 100 -1.216 0.274 1 0050789 regulation of biological process P 0 0 0 0 0 20 47 47 42.55319 100 -1.164 0.277 1 0050794 regulation of cellular process P 0 0 0 0 0 20 47 47 42.55319 100 -1.164 0.277 1 0065007 biological regulation P 0 0 0 0 0 20 47 47 42.55319 100 -1.164 0.277 1 0008757 S-adenosylmethionine-dependent methyltransferase activity F 1 1 1 100 100 2 7 7 28.57143 100 -1.178 0.28 1 0006796 phosphate-containing compound metabolic process P 1 1 1 100 100 44 97 97 45.36082 100 -1.149 0.281 1 0006073 cellular glucan metabolic process P 0 0 0 0 0 3 3 3 100 100 1.71 0.285 1 0005977 glycogen metabolic process P 1 1 1 100 100 3 3 3 100 100 1.71 0.285 1 0044042 glucan metabolic process P 0 0 0 0 0 3 3 3 100 100 1.71 0.285 1 0006112 energy reserve metabolic process P 0 0 0 0 0 3 3 3 100 100 1.71 0.285 1 0009250 glucan biosynthetic process P 1 1 1 100 100 3 3 3 100 100 1.71 0.285 1 0005978 glycogen biosynthetic process P 3 3 3 100 100 3 3 3 100 100 1.71 0.285 1 0070727 cellular macromolecule localization P 0 0 0 0 0 6 8 8 75 100 1.381 0.285 1 0034613 cellular protein localization P 0 0 0 0 0 6 8 8 75 100 1.381 0.285 1 0015075 ion transmembrane transporter activity F 0 0 0 0 0 9 23 23 39.13044 100 -1.132 0.287 1 0005488 binding F 0 0 0 0 0 180 342 344 52.63158 99.4186 1.051 0.295 1 0016903 oxidoreductase activity, acting on the aldehyde or oxo group of donors F 0 0 0 0 0 2 7 7 28.57143 100 -1.178 0.296 1 0044085 cellular component biogenesis P 0 0 0 0 0 10 25 25 40 100 -1.094 0.302 1 0046034 ATP metabolic process P 1 3 3 33.33333 100 9 23 23 39.13044 100 -1.132 0.304 1 0005215 transporter activity F 7 18 18 38.88889 100 23 53 53 43.39622 100 -1.114 0.308 1 0006096 glycolysis P 3 9 9 33.33333 100 3 9 9 33.33333 100 -1.05 0.314 1 0016310 phosphorylation P 8 22 22 36.36364 100 9 23 23 39.13044 100 -1.132 0.316 1 0006163 purine nucleotide metabolic process P 1 2 2 50 100 17 40 40 42.5 100 -1.074 0.319 1 0009123 nucleoside monophosphate metabolic process P 0 0 0 0 0 11 27 27 40.74074 100 -1.06 0.322 1 0046903 secretion P 0 1 1 0 100 6 16 16 37.5 100 -1.071 0.323 1 0009306 protein secretion P 3 9 9 33.33333 100 6 16 16 37.5 100 -1.071 0.323 1 0032940 secretion by cell P 0 0 0 0 0 6 16 16 37.5 100 -1.071 0.323 1 0072521 purine-containing compound metabolic process P 0 0 0 0 0 18 42 42 42.85714 100 -1.055 0.325 1 0004540 ribonuclease activity F 1 2 2 50 100 3 9 9 33.33333 100 -1.05 0.334 1 0044272 sulfur compound biosynthetic process P 0 0 0 0 0 1 4 4 25 100 -1.031 0.342 1 0006353 DNA-dependent transcription, termination P 1 3 3 33.33333 100 1 4 4 25 100 -1.031 0.343 1 0000287 magnesium ion binding F 12 19 19 63.15789 100 12 19 19 63.15789 100 1.1 0.345 1 0008135 translation factor activity, nucleic acid binding F 0 0 0 0 0 7 10 11 70 90.90909 1.228 0.347 1 0009103 lipopolysaccharide biosynthetic process P 1 3 3 33.33333 100 1 4 4 25 100 -1.031 0.347 1 0008653 lipopolysaccharide metabolic process P 0 0 0 0 0 1 4 4 25 100 -1.031 0.347 1 0016757 transferase activity, transferring glycosyl groups F 3 9 9 33.33333 100 3 9 9 33.33333 100 -1.05 0.347 1 0005506 iron ion binding F 1 4 4 25 100 1 4 4 25 100 -1.031 0.348 1 0042440 pigment metabolic process P 0 0 0 0 0 1 4 4 25 100 -1.031 0.349 1 0046148 pigment biosynthetic process P 0 0 0 0 0 1 4 4 25 100 -1.031 0.349 1 0042168 heme metabolic process P 0 0 0 0 0 1 4 4 25 100 -1.031 0.349 1 0006783 heme biosynthetic process P 0 1 1 0 100 1 4 4 25 100 -1.031 0.349 1 0006091 generation of precursor metabolites and energy P 0 0 0 0 0 8 20 20 40 100 -0.974 0.35 1 0016814 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines F 0 0 0 0 0 1 4 4 25 100 -1.031 0.352 1 0070566 adenylyltransferase activity F 0 0 0 0 0 1 4 4 25 100 -1.031 0.354 1 0016861 intramolecular oxidoreductase activity, interconverting aldoses and ketoses F 0 0 0 0 0 1 4 4 25 100 -1.031 0.355 1 0043038 amino acid activation P 0 0 0 0 0 12 19 19 63.15789 100 1.1 0.356 1 0043039 tRNA aminoacylation P 1 4 4 25 100 12 19 19 63.15789 100 1.1 0.356 1 0004812 aminoacyl-tRNA ligase activity F 12 19 19 63.15789 100 12 19 19 63.15789 100 1.1 0.356 1 0016875 ligase activity, forming carbon-oxygen bonds F 0 0 0 0 0 12 19 19 63.15789 100 1.1 0.356 1 0006418 tRNA aminoacylation for protein translation P 11 16 16 68.75 100 12 19 19 63.15789 100 1.1 0.356 1 0016876 ligase activity, forming aminoacyl-tRNA and related compounds F 1 3 3 33.33333 100 12 19 19 63.15789 100 1.1 0.356 1 0042398 cellular modified amino acid biosynthetic process P 0 0 0 0 0 1 4 4 25 100 -1.031 0.357 1 0090407 organophosphate biosynthetic process P 0 0 0 0 0 18 42 42 42.85714 100 -1.055 0.359 1 0016469 proton-transporting two-sector ATPase complex C 0 0 0 0 0 1 4 4 25 100 -1.031 0.362 1 0015988 energy coupled proton transmembrane transport, against electrochemical gradient P 0 0 0 0 0 1 4 4 25 100 -1.031 0.362 1 0015991 ATP hydrolysis coupled proton transport P 1 4 4 25 100 1 4 4 25 100 -1.031 0.362 1 0008168 methyltransferase activity F 6 17 17 35.29412 100 7 18 18 38.88889 100 -1.018 0.365 1 0005618 cell wall C 0 0 0 0 0 1 4 4 25 100 -1.031 0.366 1 0009276 Gram-negative-bacterium-type cell wall C 1 4 4 25 100 1 4 4 25 100 -1.031 0.366 1 0009274 peptidoglycan-based cell wall C 0 0 0 0 0 1 4 4 25 100 -1.031 0.366 1 0006950 response to stress P 7 9 9 77.77778 100 14 33 33 42.42424 100 -0.979 0.367 1 0006164 purine nucleotide biosynthetic process P 0 1 1 0 100 4 11 11 36.36364 100 -0.96 0.369 1 0072522 purine-containing compound biosynthetic process P 0 0 0 0 0 4 11 11 36.36364 100 -0.96 0.369 1 0046933 proton-transporting ATP synthase activity, rotational mechanism F 1 4 4 25 100 1 4 4 25 100 -1.031 0.369 1 0015986 ATP synthesis coupled proton transport P 0 0 0 0 0 1 4 4 25 100 -1.031 0.369 1 0042777 plasma membrane ATP synthesis coupled proton transport P 1 4 4 25 100 1 4 4 25 100 -1.031 0.369 1 0015985 energy coupled proton transport, down electrochemical gradient P 0 0 0 0 0 1 4 4 25 100 -1.031 0.369 1 0006650 glycerophospholipid metabolic process P 0 2 2 0 100 1 4 4 25 100 -1.031 0.371 1 0004672 protein kinase activity F 1 3 3 33.33333 100 1 4 4 25 100 -1.031 0.371 1 0046486 glycerolipid metabolic process P 0 0 0 0 0 1 4 4 25 100 -1.031 0.371 1 0071705 nitrogen compound transport P 0 0 0 0 0 8 12 13 66.66666 92.30769 1.115 0.374 1 0022613 ribonucleoprotein complex biogenesis P 0 0 0 0 0 4 11 11 36.36364 100 -0.96 0.376 1 0042254 ribosome biogenesis P 2 4 4 50 100 4 11 11 36.36364 100 -0.96 0.376 1 0009225 nucleotide-sugar metabolic process P 0 0 0 0 0 1 4 4 25 100 -1.031 0.377 1 0009226 nucleotide-sugar biosynthetic process P 0 0 0 0 0 1 4 4 25 100 -1.031 0.377 1 0051049 regulation of transport P 0 0 0 0 0 1 4 4 25 100 -1.031 0.379 1 0032880 regulation of protein localization P 0 0 0 0 0 1 4 4 25 100 -1.031 0.379 1 0008026 ATP-dependent helicase activity F 0 2 2 0 100 1 4 4 25 100 -1.031 0.379 1 0070201 regulation of establishment of protein localization P 0 0 0 0 0 1 4 4 25 100 -1.031 0.379 1 0051223 regulation of protein transport P 0 0 0 0 0 1 4 4 25 100 -1.031 0.379 1 0051046 regulation of secretion P 0 0 0 0 0 1 4 4 25 100 -1.031 0.379 1 0032879 regulation of localization P 0 0 0 0 0 1 4 4 25 100 -1.031 0.379 1 0060341 regulation of cellular localization P 0 0 0 0 0 1 4 4 25 100 -1.031 0.379 1 0070035 purine NTP-dependent helicase activity F 0 0 0 0 0 1 4 4 25 100 -1.031 0.379 1 0050708 regulation of protein secretion P 1 3 3 33.33333 100 1 4 4 25 100 -1.031 0.379 1 0006260 DNA replication P 6 18 18 33.33333 100 9 22 22 40.90909 100 -0.937 0.38 1 0009295 nucleoid C 4 5 5 80 100 4 5 5 80 100 1.314 0.381 1 0016667 oxidoreductase activity, acting on a sulfur group of donors F 0 0 0 0 0 4 5 5 80 100 1.314 0.383 1 0016624 oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor F 1 3 3 33.33333 100 1 4 4 25 100 -1.031 0.386 1 0004252 serine-type endopeptidase activity F 4 5 5 80 100 4 5 5 80 100 1.314 0.389 1 0048037 cofactor binding F 0 1 1 0 100 16 37 37 43.24324 100 -0.937 0.389 1 0016779 nucleotidyltransferase activity F 9 20 20 45 100 9 22 22 40.90909 100 -0.937 0.39 1 0016773 phosphotransferase activity, alcohol group as acceptor F 0 0 0 0 0 5 13 13 38.46154 100 -0.893 0.392 1 0046128 purine ribonucleoside metabolic process P 0 0 0 0 0 17 39 39 43.58974 100 -0.919 0.392 1 0042278 purine nucleoside metabolic process P 0 0 0 0 0 17 39 39 43.58974 100 -0.919 0.392 1 0043436 oxoacid metabolic process P 0 0 0 0 0 40 71 72 56.33803 98.61111 1.005 0.393 1 0019752 carboxylic acid metabolic process P 0 0 0 0 0 40 71 72 56.33803 98.61111 1.005 0.393 1 0006082 organic acid metabolic process P 0 0 0 0 0 40 71 72 56.33803 98.61111 1.005 0.393 1 0046394 carboxylic acid biosynthetic process P 0 0 0 0 0 20 34 35 58.82353 97.14286 0.971 0.393 1 0016053 organic acid biosynthetic process P 0 0 0 0 0 20 34 35 58.82353 97.14286 0.971 0.393 1 0009150 purine ribonucleotide metabolic process P 0 0 0 0 0 16 37 37 43.24324 100 -0.937 0.395 1 0007165 signal transduction P 0 2 2 0 100 1 4 4 25 100 -1.031 0.402 1 0023052 signaling P 0 0 0 0 0 1 4 4 25 100 -1.031 0.402 1 0044700 single organism signaling P 0 0 0 0 0 1 4 4 25 100 -1.031 0.402 1 0004871 signal transducer activity F 0 2 2 0 100 1 4 4 25 100 -1.031 0.402 1 0060089 molecular transducer activity F 0 0 0 0 0 1 4 4 25 100 -1.031 0.402 1 0006265 DNA topological change P 4 5 5 80 100 4 5 5 80 100 1.314 0.406 1 0003916 DNA topoisomerase activity F 3 4 4 75 100 4 5 5 80 100 1.314 0.406 1 0050662 coenzyme binding F 0 2 2 0 100 11 26 26 42.30769 100 -0.876 0.408 1 0044710 single-organism metabolic process P 0 0 0 0 0 97 202 203 48.0198 99.50739 -0.934 0.41 1 0010468 regulation of gene expression P 0 0 0 0 0 11 26 26 42.30769 100 -0.876 0.411 1 0097159 organic cyclic compound binding F 0 0 0 0 0 149 283 285 52.65018 99.29825 0.877 0.412 1 1901363 heterocyclic compound binding F 0 0 0 0 0 149 283 285 52.65018 99.29825 0.877 0.412 1 0009067 aspartate family amino acid biosynthetic process P 0 0 0 0 0 5 7 7 71.42857 100 1.101 0.414 1 0009066 aspartate family amino acid metabolic process P 0 0 0 0 0 5 7 7 71.42857 100 1.101 0.414 1 2000112 regulation of cellular macromolecule biosynthetic process P 0 0 0 0 0 12 28 28 42.85714 100 -0.851 0.417 1 0060255 regulation of macromolecule metabolic process P 0 0 0 0 0 12 28 28 42.85714 100 -0.851 0.417 1 0009889 regulation of biosynthetic process P 0 0 0 0 0 12 28 28 42.85714 100 -0.851 0.417 1 0031326 regulation of cellular biosynthetic process P 0 0 0 0 0 12 28 28 42.85714 100 -0.851 0.417 1 0019222 regulation of metabolic process P 0 0 0 0 0 12 28 28 42.85714 100 -0.851 0.417 1 0010556 regulation of macromolecule biosynthetic process P 0 0 0 0 0 12 28 28 42.85714 100 -0.851 0.417 1 0031323 regulation of cellular metabolic process P 0 0 0 0 0 12 28 28 42.85714 100 -0.851 0.417 1 0080090 regulation of primary metabolic process P 0 0 0 0 0 12 28 28 42.85714 100 -0.851 0.417 1 0034470 ncRNA processing P 0 0 0 0 0 11 26 27 42.30769 96.2963 -0.876 0.422 1 0006753 nucleoside phosphate metabolic process P 0 0 0 0 0 27 60 60 45 100 -0.932 0.425 1 0009117 nucleotide metabolic process P 3 4 4 75 100 27 60 60 45 100 -0.932 0.425 1 0055086 nucleobase-containing small molecule metabolic process P 0 0 0 0 0 29 64 64 45.3125 100 -0.913 0.428 1 0016043 cellular component organization P 0 0 0 0 0 16 27 28 59.25926 96.42857 0.906 0.43 1 0006605 protein targeting P 3 5 5 60 100 5 7 7 71.42857 100 1.101 0.439 1 0046907 intracellular transport P 0 0 0 0 0 5 7 7 71.42857 100 1.101 0.439 1 0006886 intracellular protein transport P 2 3 3 66.66666 100 5 7 7 71.42857 100 1.101 0.439 1 0016655 oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor F 2 6 6 33.33333 100 2 6 6 33.33333 100 -0.855 0.442 1 0042625 ATPase activity, coupled to transmembrane movement of ions F 0 0 0 0 0 2 6 6 33.33333 100 -0.855 0.443 1 0019829 cation-transporting ATPase activity F 0 1 1 0 100 2 6 6 33.33333 100 -0.855 0.443 1 0043650 dicarboxylic acid biosynthetic process P 0 0 0 0 0 2 6 6 33.33333 100 -0.855 0.446 1 0009452 7-methylguanosine RNA capping P 0 0 0 0 0 0 1 1 0 100 -1.015 0.446 1 0036260 RNA capping P 0 0 0 0 0 0 1 1 0 100 -1.015 0.446 1 0008176 tRNA (guanine-N7-)-methyltransferase activity F 0 1 1 0 100 0 1 1 0 100 -1.015 0.446 1 0036265 RNA (guanine-N7)-methylation P 0 1 1 0 100 0 1 1 0 100 -1.015 0.446 1 0006520 cellular amino acid metabolic process P 1 3 3 33.33333 100 26 46 47 56.52174 97.87234 0.817 0.447 1 0009168 purine ribonucleoside monophosphate biosynthetic process P 0 0 0 0 0 2 6 6 33.33333 100 -0.855 0.454 1 0009127 purine nucleoside monophosphate biosynthetic process P 0 0 0 0 0 2 6 6 33.33333 100 -0.855 0.454 1 0009156 ribonucleoside monophosphate biosynthetic process P 0 0 0 0 0 2 6 6 33.33333 100 -0.855 0.454 1 0004764 shikimate 3-dehydrogenase (NADP+) activity F 0 1 1 0 100 0 1 1 0 100 -1.015 0.457 1 1901615 organic hydroxy compound metabolic process P 0 0 0 0 0 0 1 1 0 100 -1.015 0.457 1 0003855 3-dehydroquinate dehydratase activity F 0 1 1 0 100 0 1 1 0 100 -1.015 0.457 1 0019632 shikimate metabolic process P 0 1 1 0 100 0 1 1 0 100 -1.015 0.457 1 0006396 RNA processing P 5 9 9 55.55556 100 14 32 33 43.75 96.9697 -0.809 0.458 1 0016894 endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 3’-phosphomonoesters F 0 0 0 0 0 0 1 1 0 100 -1.015 0.458 1 0016889 endodeoxyribonuclease activity, producing 3’-phosphomonoesters F 0 0 0 0 0 0 1 1 0 100 -1.015 0.458 1 0008821 crossover junction endodeoxyribonuclease activity F 0 1 1 0 100 0 1 1 0 100 -1.015 0.458 1 0009893 positive regulation of metabolic process P 0 0 0 0 0 0 1 1 0 100 -1.015 0.464 1 0048522 positive regulation of cellular process P 0 0 0 0 0 0 1 1 0 100 -1.015 0.464 1 0031325 positive regulation of cellular metabolic process P 0 0 0 0 0 0 1 1 0 100 -1.015 0.464 1 0008793 aromatic-amino-acid:2-oxoglutarate aminotransferase activity F 0 1 1 0 100 0 1 1 0 100 -1.015 0.464 1 0031328 positive regulation of cellular biosynthetic process P 0 0 0 0 0 0 1 1 0 100 -1.015 0.464 1 0051247 positive regulation of protein metabolic process P 0 0 0 0 0 0 1 1 0 100 -1.015 0.464 1 0010557 positive regulation of macromolecule biosynthetic process P 0 0 0 0 0 0 1 1 0 100 -1.015 0.464 1 0043021 ribonucleoprotein complex binding F 0 0 0 0 0 0 1 1 0 100 -1.015 0.464 1 0032270 positive regulation of cellular protein metabolic process P 0 0 0 0 0 0 1 1 0 100 -1.015 0.464 1 0010604 positive regulation of macromolecule metabolic process P 0 0 0 0 0 0 1 1 0 100 -1.015 0.464 1 0048518 positive regulation of biological process P 0 0 0 0 0 0 1 1 0 100 -1.015 0.464 1 0009891 positive regulation of biosynthetic process P 0 0 0 0 0 0 1 1 0 100 -1.015 0.464 1 0043022 ribosome binding F 0 1 1 0 100 0 1 1 0 100 -1.015 0.464 1 0080130 L-phenylalanine:2-oxoglutarate aminotransferase activity F 0 1 1 0 100 0 1 1 0 100 -1.015 0.464 1 0045727 positive regulation of translation P 0 1 1 0 100 0 1 1 0 100 -1.015 0.464 1 0070546 L-phenylalanine aminotransferase activity F 0 0 0 0 0 0 1 1 0 100 -1.015 0.464 1 0019205 nucleobase-containing compound kinase activity F 0 1 1 0 100 2 6 6 33.33333 100 -0.855 0.465 1 0004477 methenyltetrahydrofolate cyclohydrolase activity F 0 1 1 0 100 0 1 1 0 100 -1.015 0.466 1 0000105 histidine biosynthetic process P 0 1 1 0 100 0 1 1 0 100 -1.015 0.466 1 0004488 methylenetetrahydrofolate dehydrogenase (NADP+) activity F 0 1 1 0 100 0 1 1 0 100 -1.015 0.466 1 0052803 imidazole-containing compound metabolic process P 0 0 0 0 0 0 1 1 0 100 -1.015 0.466 1 0006547 histidine metabolic process P 0 0 0 0 0 0 1 1 0 100 -1.015 0.466 1 0004549 tRNA-specific ribonuclease activity F 0 0 0 0 0 0 1 1 0 100 -1.015 0.468 1 0004526 ribonuclease P activity F 0 1 1 0 100 0 1 1 0 100 -1.015 0.468 1 0022857 transmembrane transporter activity F 0 0 0 0 0 15 34 34 44.11765 100 -0.792 0.469 1 0008835 diaminohydroxyphosphoribosylaminopyrimidine deaminase activity F 0 1 1 0 100 0 1 1 0 100 -1.015 0.47 1 0008703 5-amino-6-(5-phosphoribosylamino)uracil reductase activity F 0 1 1 0 100 0 1 1 0 100 -1.015 0.47 1 1901135 carbohydrate derivative metabolic process P 0 0 0 0 0 37 79 79 46.83544 100 -0.739 0.471 1 0051051 negative regulation of transport P 0 0 0 0 0 0 1 1 0 100 -1.015 0.471 1 0004609 phosphatidylserine decarboxylase activity F 0 1 1 0 100 0 1 1 0 100 -1.015 0.471 1 0047617 acyl-CoA hydrolase activity F 0 1 1 0 100 0 1 1 0 100 -1.015 0.471 1 0046337 phosphatidylethanolamine metabolic process P 0 0 0 0 0 0 1 1 0 100 -1.015 0.471 1 0050709 negative regulation of protein secretion P 0 1 1 0 100 0 1 1 0 100 -1.015 0.471 1 0016434 rRNA (cytosine) methyltransferase activity F 0 0 0 0 0 0 1 1 0 100 -1.015 0.471 1 0071424 rRNA (cytosine-N4-)-methyltransferase activity F 0 1 1 0 100 0 1 1 0 100 -1.015 0.471 1 0070475 rRNA base methylation P 0 1 1 0 100 0 1 1 0 100 -1.015 0.471 1 0051224 negative regulation of protein transport P 0 0 0 0 0 0 1 1 0 100 -1.015 0.471 1 0016289 CoA hydrolase activity F 0 0 0 0 0 0 1 1 0 100 -1.015 0.471 1 0046474 glycerophospholipid biosynthetic process P 0 0 0 0 0 0 1 1 0 100 -1.015 0.471 1 0016790 thiolester hydrolase activity F 0 0 0 0 0 0 1 1 0 100 -1.015 0.471 1 0051048 negative regulation of secretion P 0 0 0 0 0 0 1 1 0 100 -1.015 0.471 1 0045017 glycerolipid biosynthetic process P 0 0 0 0 0 0 1 1 0 100 -1.015 0.471 1 0006646 phosphatidylethanolamine biosynthetic process P 0 1 1 0 100 0 1 1 0 100 -1.015 0.471 1 0006541 glutamine metabolic process P 2 2 2 100 100 2 2 2 100 100 1.395 0.472 1 0008150 biological_process P 0 0 0 0 0 281 548 552 51.27737 99.27536 0.748 0.472 1 0004721 phosphoprotein phosphatase activity F 0 1 1 0 100 0 1 1 0 100 -1.015 0.472 1 0015103 inorganic anion transmembrane transporter activity F 0 0 0 0 0 0 1 1 0 100 -1.015 0.473 1 0015116 sulfate transmembrane transporter activity F 0 1 1 0 100 0 1 1 0 100 -1.015 0.473 1 0008272 sulfate transport P 0 1 1 0 100 0 1 1 0 100 -1.015 0.473 1 0008271 secondary active sulfate transmembrane transporter activity F 0 1 1 0 100 0 1 1 0 100 -1.015 0.473 1 1901682 sulfur compound transmembrane transporter activity F 0 0 0 0 0 0 1 1 0 100 -1.015 0.473 1 0005201 extracellular matrix structural constituent F 2 2 2 100 100 2 2 2 100 100 1.395 0.474 1 0031124 mRNA 3’-end processing P 0 0 0 0 0 0 1 1 0 100 -1.015 0.474 1 0043631 RNA polyadenylation P 0 0 0 0 0 0 1 1 0 100 -1.015 0.474 1 0006378 mRNA polyadenylation P 0 1 1 0 100 0 1 1 0 100 -1.015 0.474 1 0042597 periplasmic space C 2 2 2 100 100 2 2 2 100 100 1.395 0.475 1 0009082 branched-chain amino acid biosynthetic process P 0 0 0 0 0 0 1 1 0 100 -1.015 0.475 1 0009081 branched-chain amino acid metabolic process P 0 0 0 0 0 0 1 1 0 100 -1.015 0.475 1 0006549 isoleucine metabolic process P 0 0 0 0 0 0 1 1 0 100 -1.015 0.475 1 0003942 N-acetyl-gamma-glutamyl-phosphate reductase activity F 0 1 1 0 100 0 1 1 0 100 -1.015 0.475 1 0004073 aspartate-semialdehyde dehydrogenase activity F 0 1 1 0 100 0 1 1 0 100 -1.015 0.475 1 0009097 isoleucine biosynthetic process P 0 1 1 0 100 0 1 1 0 100 -1.015 0.475 1 0006531 aspartate metabolic process P 0 1 1 0 100 0 1 1 0 100 -1.015 0.475 1 0043165 Gram-negative-bacterium-type cell outer membrane assembly P 0 1 1 0 100 0 1 1 0 100 -1.015 0.476 1 0071709 membrane assembly P 0 0 0 0 0 0 1 1 0 100 -1.015 0.476 1 0043163 cell envelope organization P 0 0 0 0 0 0 1 1 0 100 -1.015 0.476 1 0044091 membrane biogenesis P 0 0 0 0 0 0 1 1 0 100 -1.015 0.476 1 0045229 external encapsulating structure organization P 0 0 0 0 0 0 1 1 0 100 -1.015 0.476 1 0008883 glutamyl-tRNA reductase activity F 0 1 1 0 100 0 1 1 0 100 -1.015 0.476 1 0004618 phosphoglycerate kinase activity F 0 1 1 0 100 0 1 1 0 100 -1.015 0.477 1 0004730 pseudouridylate synthase activity F 2 2 3 100 66.66666 2 2 3 100 66.66666 1.395 0.478 1 0033202 DNA helicase complex C 0 0 0 0 0 0 1 1 0 100 -1.015 0.478 1 0048476 Holliday junction resolvase complex C 0 0 0 0 0 0 1 1 0 100 -1.015 0.478 1 0004325 ferrochelatase activity F 0 1 1 0 100 0 1 1 0 100 -1.015 0.478 1 0009379 Holliday junction helicase complex C 0 1 1 0 100 0 1 1 0 100 -1.015 0.478 1 0003977 UDP-N-acetylglucosamine diphosphorylase activity F 0 1 1 0 100 0 1 1 0 100 -1.015 0.479 1 0004813 alanine-tRNA ligase activity F 0 1 1 0 100 0 1 1 0 100 -1.015 0.479 1 0070569 uridylyltransferase activity F 0 0 0 0 0 0 1 1 0 100 -1.015 0.479 1 0006419 alanyl-tRNA aminoacylation P 0 1 1 0 100 0 1 1 0 100 -1.015 0.479 1 0006106 fumarate metabolic process P 0 1 1 0 100 0 1 1 0 100 -1.015 0.48 1 0004333 fumarate hydratase activity F 0 1 1 0 100 0 1 1 0 100 -1.015 0.48 1 0006221 pyrimidine nucleotide biosynthetic process P 2 2 2 100 100 5 7 7 71.42857 100 1.101 0.481 1 0015036 disulfide oxidoreductase activity F 0 0 0 0 0 2 2 2 100 100 1.395 0.482 1 0016726 oxidoreductase activity, acting on CH or CH2 groups, NAD or NADP as acceptor F 1 1 1 100 100 2 2 2 100 100 1.395 0.482 1 0015035 protein disulfide oxidoreductase activity F 2 2 2 100 100 2 2 2 100 100 1.395 0.482 1 0033176 proton-transporting V-type ATPase complex C 0 0 0 0 0 0 1 1 0 100 -1.015 0.482 1 0033179 proton-transporting V-type ATPase, V0 domain C 0 1 1 0 100 0 1 1 0 100 -1.015 0.482 1 0009119 ribonucleoside metabolic process P 0 0 0 0 0 19 42 42 45.23809 100 -0.736 0.483 1 0008253 5’-nucleotidase activity F 0 1 1 0 100 0 1 1 0 100 -1.015 0.483 1 0004640 phosphoribosylanthranilate isomerase activity F 0 1 1 0 100 0 1 1 0 100 -1.015 0.483 1 0004844 uracil DNA N-glycosylase activity F 0 1 1 0 100 0 1 1 0 100 -1.015 0.483 1 0097506 deaminated base DNA N-glycosylase activity F 0 0 0 0 0 0 1 1 0 100 -1.015 0.483 1 0006545 glycine biosynthetic process P 2 2 2 100 100 2 2 2 100 100 1.395 0.484 1 0004054 arginine kinase activity F 0 1 1 0 100 0 1 1 0 100 -1.015 0.484 1 0004746 riboflavin synthase activity F 0 1 1 0 100 0 1 1 0 100 -1.015 0.484 1 0031226 intrinsic to plasma membrane C 1 1 1 100 100 2 2 2 100 100 1.395 0.485 1 0044459 plasma membrane part C 0 0 0 0 0 2 2 2 100 100 1.395 0.485 1 0008236 serine-type peptidase activity F 4 6 6 66.66666 100 6 9 9 66.66666 100 0.963 0.485 1 0017171 serine hydrolase activity F 0 0 0 0 0 6 9 9 66.66666 100 0.963 0.485 1 0004185 serine-type carboxypeptidase activity F 0 0 0 0 0 0 1 1 0 100 -1.015 0.485 1 0070008 serine-type exopeptidase activity F 0 0 0 0 0 0 1 1 0 100 -1.015 0.485 1 0046429 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase activity F 0 1 1 0 100 0 1 1 0 100 -1.015 0.485 1 0004385 guanylate kinase activity F 0 1 1 0 100 0 1 1 0 100 -1.015 0.485 1 0044781 bacterial-type flagellum organization P 0 1 1 0 100 0 1 1 0 100 -1.015 0.485 1 0052592 oxidoreductase activity, acting on CH or CH2 groups, with an iron-sulfur protein as acceptor F 0 0 0 0 0 0 1 1 0 100 -1.015 0.485 1 0004807 triose-phosphate isomerase activity F 0 1 1 0 100 0 1 1 0 100 -1.015 0.485 1 0004347 glucose-6-phosphate isomerase activity F 0 1 1 0 100 0 1 1 0 100 -1.015 0.485 1 0004180 carboxypeptidase activity F 0 1 1 0 100 0 1 1 0 100 -1.015 0.485 1 0009002 serine-type D-Ala-D-Ala carboxypeptidase activity F 0 1 1 0 100 0 1 1 0 100 -1.015 0.485 1 0030030 cell projection organization P 0 0 0 0 0 0 1 1 0 100 -1.015 0.485 1 0003908 methylated-DNA-[protein]-cysteine S-methyltransferase activity F 0 1 1 0 100 0 1 1 0 100 -1.015 0.486 1 0008172 S-methyltransferase activity F 0 0 0 0 0 0 1 1 0 100 -1.015 0.486 1 0004750 ribulose-phosphate 3-epimerase activity F 0 1 1 0 100 0 1 1 0 100 -1.015 0.488 1 0016857 racemase and epimerase activity, acting on carbohydrates and derivatives F 0 1 1 0 100 0 1 1 0 100 -1.015 0.488 1 0005960 glycine cleavage complex C 0 1 1 0 100 0 1 1 0 100 -1.015 0.488 1 0016763 transferase activity, transferring pentosyl groups F 0 0 0 0 0 0 1 1 0 100 -1.015 0.488 1 0046116 queuosine metabolic process P 0 0 0 0 0 0 1 1 0 100 -1.015 0.488 1 0009071 serine family amino acid catabolic process P 0 0 0 0 0 0 1 1 0 100 -1.015 0.488 1 0004673 protein histidine kinase activity F 0 0 0 0 0 0 1 1 0 100 -1.015 0.488 1 0019464 glycine decarboxylation via glycine cleavage system P 0 1 1 0 100 0 1 1 0 100 -1.015 0.488 1 0006546 glycine catabolic process P 0 1 1 0 100 0 1 1 0 100 -1.015 0.488 1 0038023 signaling receptor activity F 0 0 0 0 0 0 1 1 0 100 -1.015 0.488 1 0023014 signal transduction by phosphorylation P 0 1 1 0 100 0 1 1 0 100 -1.015 0.488 1 0000155 phosphorelay sensor kinase activity F 0 1 1 0 100 0 1 1 0 100 -1.015 0.488 1 0008616 queuosine biosynthetic process P 0 1 1 0 100 0 1 1 0 100 -1.015 0.488 1 0008479 queuine tRNA-ribosyltransferase activity F 0 1 1 0 100 0 1 1 0 100 -1.015 0.488 1 0004872 receptor activity F 0 0 0 0 0 0 1 1 0 100 -1.015 0.488 1 0018208 peptidyl-proline modification P 1 1 1 100 100 2 2 2 100 100 1.395 0.489 1 0003755 peptidyl-prolyl cis-trans isomerase activity F 2 2 2 100 100 2 2 2 100 100 1.395 0.489 1 0000413 protein peptidyl-prolyl isomerization P 2 2 2 100 100 2 2 2 100 100 1.395 0.489 1 0018193 peptidyl-amino acid modification P 0 0 0 0 0 2 2 2 100 100 1.395 0.489 1 0016859 cis-trans isomerase activity F 0 0 0 0 0 2 2 2 100 100 1.395 0.489 1 0043628 ncRNA 3’-end processing P 0 0 0 0 0 0 1 1 0 100 -1.015 0.489 1 0042781 3’-tRNA processing endoribonuclease activity F 0 1 1 0 100 0 1 1 0 100 -1.015 0.489 1 0042779 tRNA 3’-trailer cleavage P 0 1 1 0 100 0 1 1 0 100 -1.015 0.489 1 0004568 chitinase activity F 0 1 1 0 100 0 1 1 0 100 -1.015 0.489 1 0042780 tRNA 3’-end processing P 0 0 0 0 0 0 1 1 0 100 -1.015 0.489 1 0005326 neurotransmitter transporter activity F 0 0 0 0 0 0 1 1 0 100 -1.015 0.489 1 0090501 RNA phosphodiester bond hydrolysis P 0 0 0 0 0 0 1 1 0 100 -1.015 0.489 1 0005328 neurotransmitter:sodium symporter activity F 0 1 1 0 100 0 1 1 0 100 -1.015 0.489 1 0006836 neurotransmitter transport P 0 1 1 0 100 0 1 1 0 100 -1.015 0.489 1 0008239 dipeptidyl-peptidase activity F 0 1 1 0 100 0 1 1 0 100 -1.015 0.489 1 0004140 dephospho-CoA kinase activity F 0 1 1 0 100 0 1 1 0 100 -1.015 0.49 1 0016864 intramolecular oxidoreductase activity, transposing S-S bonds F 0 0 0 0 0 2 2 2 100 100 1.395 0.491 1 0003756 protein disulfide isomerase activity F 2 2 2 100 100 2 2 2 100 100 1.395 0.491 1 0006085 acetyl-CoA biosynthetic process P 0 0 0 0 0 0 1 1 0 100 -1.015 0.491 1 0035384 thioester biosynthetic process P 0 0 0 0 0 0 1 1 0 100 -1.015 0.491 1 0006637 acyl-CoA metabolic process P 0 0 0 0 0 0 1 1 0 100 -1.015 0.491 1 0071616 acyl-CoA biosynthetic process P 0 0 0 0 0 0 1 1 0 100 -1.015 0.491 1 0006084 acetyl-CoA metabolic process P 0 0 0 0 0 0 1 1 0 100 -1.015 0.491 1 0035383 thioester metabolic process P 0 0 0 0 0 0 1 1 0 100 -1.015 0.491 1 0006086 acetyl-CoA biosynthetic process from pyruvate P 0 1 1 0 100 0 1 1 0 100 -1.015 0.491 1 0032261 purine nucleotide salvage P 0 0 0 0 0 0 1 1 0 100 -1.015 0.492 1 0043101 purine-containing compound salvage P 0 0 0 0 0 0 1 1 0 100 -1.015 0.492 1 0006167 AMP biosynthetic process P 0 0 0 0 0 0 1 1 0 100 -1.015 0.492 1 0004017 adenylate kinase activity F 0 1 1 0 100 0 1 1 0 100 -1.015 0.492 1 0044209 AMP salvage P 0 1 1 0 100 0 1 1 0 100 -1.015 0.492 1 0043094 cellular metabolic compound salvage P 0 0 0 0 0 0 1 1 0 100 -1.015 0.492 1 0043173 nucleotide salvage P 0 0 0 0 0 0 1 1 0 100 -1.015 0.492 1 0034661 ncRNA catabolic process P 0 0 0 0 0 0 1 1 0 100 -1.015 0.492 1 0016075 rRNA catabolic process P 0 1 1 0 100 0 1 1 0 100 -1.015 0.492 1 0004525 ribonuclease III activity F 0 1 1 0 100 0 1 1 0 100 -1.015 0.492 1 0046033 AMP metabolic process P 0 0 0 0 0 0 1 1 0 100 -1.015 0.492 1 0008375 acetylglucosaminyltransferase activity F 0 0 0 0 0 0 1 1 0 100 -1.015 0.493 1 0008792 arginine decarboxylase activity F 0 1 1 0 100 0 1 1 0 100 -1.015 0.493 1 0050511 undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase activity F 0 1 1 0 100 0 1 1 0 100 -1.015 0.493 1 0006527 arginine catabolic process P 0 1 1 0 100 0 1 1 0 100 -1.015 0.493 1 0070085 glycosylation P 0 0 0 0 0 0 1 1 0 100 -1.015 0.493 1 0009065 glutamine family amino acid catabolic process P 0 0 0 0 0 0 1 1 0 100 -1.015 0.493 1 0051991 UDP-N-acetyl-D-glucosamine:N-acetylmuramoyl-L-alanyl-D-glutamyl-meso-2,6-diaminopimelyl-D-alanyl-D-alanine-diphosphoundecaprenol 4-beta-N-acetylglucosaminlytransferase activity F 0 1 1 0 100 0 1 1 0 100 -1.015 0.493 1 0006525 arginine metabolic process P 0 0 0 0 0 0 1 1 0 100 -1.015 0.493 1 0030259 lipid glycosylation P 0 1 1 0 100 0 1 1 0 100 -1.015 0.493 1 0030257 type III protein secretion system complex C 2 2 2 100 100 2 2 2 100 100 1.395 0.494 1 0043624 cellular protein complex disassembly P 0 0 0 0 0 2 2 3 100 66.66666 1.395 0.494 1 0006415 translational termination P 2 2 3 100 66.66666 2 2 3 100 66.66666 1.395 0.494 1 0008760 UDP-N-acetylglucosamine 1-carboxyvinyltransferase activity F 0 1 1 0 100 0 1 1 0 100 -1.015 0.494 1 0004832 valine-tRNA ligase activity F 0 1 1 0 100 0 1 1 0 100 -1.015 0.494 1 0008859 exoribonuclease II activity F 0 1 1 0 100 0 1 1 0 100 -1.015 0.494 1 0006438 valyl-tRNA aminoacylation P 0 1 1 0 100 0 1 1 0 100 -1.015 0.494 1 0008094 DNA-dependent ATPase activity F 2 3 3 66.66666 100 6 9 9 66.66666 100 0.963 0.495 1 0009158 ribonucleoside monophosphate catabolic process P 0 0 0 0 0 8 19 19 42.10526 100 -0.762 0.495 1 0009169 purine ribonucleoside monophosphate catabolic process P 0 0 0 0 0 8 19 19 42.10526 100 -0.762 0.495 1 0009125 nucleoside monophosphate catabolic process P 0 0 0 0 0 8 19 19 42.10526 100 -0.762 0.495 1 0006200 ATP catabolic process P 8 19 19 42.10526 100 8 19 19 42.10526 100 -0.762 0.495 1 0009128 purine nucleoside monophosphate catabolic process P 0 0 0 0 0 8 19 19 42.10526 100 -0.762 0.495 1 0070001 aspartic-type peptidase activity F 0 0 0 0 0 0 1 1 0 100 -1.015 0.495 1 0004190 aspartic-type endopeptidase activity F 0 1 1 0 100 0 1 1 0 100 -1.015 0.495 1 0052908 16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity F 0 1 1 0 100 0 1 1 0 100 -1.015 0.495 1 0008988 rRNA (adenine-N6-)-methyltransferase activity F 0 0 0 0 0 0 1 1 0 100 -1.015 0.495 1 0006072 glycerol-3-phosphate metabolic process P 0 1 1 0 100 0 1 1 0 100 -1.015 0.495 1 0004367 glycerol-3-phosphate dehydrogenase [NAD+] activity F 0 1 1 0 100 0 1 1 0 100 -1.015 0.495 1 0052646 alditol phosphate metabolic process P 0 0 0 0 0 0 1 1 0 100 -1.015 0.495 1 0047952 glycerol-3-phosphate dehydrogenase [NAD(P)+] activity F 0 1 1 0 100 0 1 1 0 100 -1.015 0.495 1 0000179 rRNA (adenine-N6,N6-)-dimethyltransferase activity F 0 1 1 0 100 0 1 1 0 100 -1.015 0.495 1 0009331 glycerol-3-phosphate dehydrogenase complex C 0 1 1 0 100 0 1 1 0 100 -1.015 0.495 1 0036439 glycerol-3-phosphate dehydrogenase [NADP+] activity F 0 1 1 0 100 0 1 1 0 100 -1.015 0.495 1 0046167 glycerol-3-phosphate biosynthetic process P 0 1 1 0 100 0 1 1 0 100 -1.015 0.495 1 0016433 rRNA (adenine) methyltransferase activity F 0 1 1 0 100 0 1 1 0 100 -1.015 0.495 1 0046168 glycerol-3-phosphate catabolic process P 0 1 1 0 100 0 1 1 0 100 -1.015 0.495 1 0008961 phosphatidylglycerol-prolipoprotein diacylglyceryl transferase activity F 0 1 1 0 100 0 1 1 0 100 -1.015 0.495 1 0008169 C-methyltransferase activity F 0 0 0 0 0 0 1 1 0 100 -1.015 0.496 1 0008833 deoxyribonuclease IV (phage-T4-induced) activity F 0 1 1 0 100 0 1 1 0 100 -1.015 0.496 1 0004851 uroporphyrin-III C-methyltransferase activity F 0 1 1 0 100 0 1 1 0 100 -1.015 0.496 1 0004852 uroporphyrinogen-III synthase activity F 0 1 1 0 100 0 1 1 0 100 -1.015 0.496 1 0070271 protein complex biogenesis P 0 0 0 0 0 0 1 1 0 100 -1.015 0.497 1 0052863 1-deoxy-D-xylulose 5-phosphate metabolic process P 0 0 0 0 0 0 1 1 0 100 -1.015 0.497 1 0006772 thiamine metabolic process P 0 0 0 0 0 0 1 1 0 100 -1.015 0.497 1 0017004 cytochrome complex assembly P 0 1 1 0 100 0 1 1 0 100 -1.015 0.497 1 0008762 UDP-N-acetylmuramate dehydrogenase activity F 0 1 1 0 100 0 1 1 0 100 -1.015 0.497 1 0042723 thiamine-containing compound metabolic process P 0 0 0 0 0 0 1 1 0 100 -1.015 0.497 1 0030604 1-deoxy-D-xylulose-5-phosphate reductoisomerase activity F 0 1 1 0 100 0 1 1 0 100 -1.015 0.497 1 0052865 1-deoxy-D-xylulose 5-phosphate biosynthetic process P 0 1 1 0 100 0 1 1 0 100 -1.015 0.497 1 0047134 protein-disulfide reductase activity F 0 1 1 0 100 0 1 1 0 100 -1.015 0.497 1 0004645 phosphorylase activity F 0 1 1 0 100 0 1 1 0 100 -1.015 0.497 1 0008661 1-deoxy-D-xylulose-5-phosphate synthase activity F 0 1 1 0 100 0 1 1 0 100 -1.015 0.497 1 0006461 protein complex assembly P 0 0 0 0 0 0 1 1 0 100 -1.015 0.497 1 0009228 thiamine biosynthetic process P 0 1 1 0 100 0 1 1 0 100 -1.015 0.497 1 0043623 cellular protein complex assembly P 0 0 0 0 0 0 1 1 0 100 -1.015 0.497 1 0008184 glycogen phosphorylase activity F 0 1 1 0 100 0 1 1 0 100 -1.015 0.497 1 0042724 thiamine-containing compound biosynthetic process P 0 0 0 0 0 0 1 1 0 100 -1.015 0.497 1 0016628 oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor F 0 0 0 0 0 2 2 2 100 100 1.395 0.498 1 0006612 protein targeting to membrane P 1 1 1 100 100 2 2 2 100 100 1.395 0.498 1 0072657 protein localization to membrane P 0 0 0 0 0 2 2 2 100 100 1.395 0.498 1 0006614 SRP-dependent cotranslational protein targeting to membrane P 2 2 2 100 100 2 2 2 100 100 1.395 0.498 1 0016482 cytoplasmic transport P 0 0 0 0 0 2 2 2 100 100 1.395 0.498 1 0090150 establishment of protein localization to membrane P 0 0 0 0 0 2 2 2 100 100 1.395 0.498 1 0006613 cotranslational protein targeting to membrane P 0 0 0 0 0 2 2 2 100 100 1.395 0.498 1 0072594 establishment of protein localization to organelle P 0 0 0 0 0 2 2 2 100 100 1.395 0.498 1 0072599 establishment of protein localization to endoplasmic reticulum P 0 0 0 0 0 2 2 2 100 100 1.395 0.498 1 0033365 protein localization to organelle P 0 0 0 0 0 2 2 2 100 100 1.395 0.498 1 0070972 protein localization to endoplasmic reticulum P 0 0 0 0 0 2 2 2 100 100 1.395 0.498 1 0045047 protein targeting to ER P 0 0 0 0 0 2 2 2 100 100 1.395 0.498 1 0016882 cyclo-ligase activity F 0 0 0 0 0 0 1 1 0 100 -1.015 0.498 1 0008186 RNA-dependent ATPase activity F 0 1 1 0 100 0 1 1 0 100 -1.015 0.498 1 0030272 5-formyltetrahydrofolate cyclo-ligase activity F 0 1 1 0 100 0 1 1 0 100 -1.015 0.498 1 0004820 glycine-tRNA ligase activity F 0 1 1 0 100 0 1 1 0 100 -1.015 0.499 1 0046912 transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer F 0 0 0 0 0 0 1 1 0 100 -1.015 0.499 1 0006426 glycyl-tRNA aminoacylation P 0 1 1 0 100 0 1 1 0 100 -1.015 0.499 1 0003878 ATP citrate synthase activity F 0 1 1 0 100 0 1 1 0 100 -1.015 0.499 1 0008320 protein transmembrane transporter activity F 0 0 0 0 0 2 2 2 100 100 1.395 0.5 1 0015450 P-P-bond-hydrolysis-driven protein transmembrane transporter activity F 2 2 2 100 100 2 2 2 100 100 1.395 0.5 1 0022884 macromolecule transmembrane transporter activity F 0 0 0 0 0 2 2 2 100 100 1.395 0.5 1 0030894 replisome C 0 0 0 0 0 0 1 1 0 100 -1.015 0.5 1 0005657 replication fork C 0 0 0 0 0 0 1 1 0 100 -1.015 0.5 1 0044427 chromosomal part C 0 0 0 0 0 0 1 1 0 100 -1.015 0.5 1 0003896 DNA primase activity F 0 1 1 0 100 0 1 1 0 100 -1.015 0.5 1 0006269 DNA replication, synthesis of RNA primer P 0 1 1 0 100 0 1 1 0 100 -1.015 0.5 1 1990077 primosome complex C 0 1 1 0 100 0 1 1 0 100 -1.015 0.5 1 0032993 protein-DNA complex C 0 0 0 0 0 0 1 1 0 100 -1.015 0.5 1 0004418 hydroxymethylbilane synthase activity F 0 1 1 0 100 0 1 1 0 100 -1.015 0.5 1 0008409 5’-3’ exonuclease activity F 2 2 2 100 100 2 2 2 100 100 1.395 0.501 1 0003725 double-stranded RNA binding F 0 1 1 0 100 0 1 1 0 100 -1.015 0.501 1 0016653 oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor F 0 0 0 0 0 0 1 1 0 100 -1.015 0.501 1 0031119 tRNA pseudouridine synthesis P 0 1 1 0 100 0 1 1 0 100 -1.015 0.501 1 0070818 protoporphyrinogen oxidase activity F 0 0 0 0 0 0 1 1 0 100 -1.015 0.501 1 0004729 oxygen-dependent protoporphyrinogen oxidase activity F 0 1 1 0 100 0 1 1 0 100 -1.015 0.501 1 0003958 NADPH-hemoprotein reductase activity F 0 1 1 0 100 0 1 1 0 100 -1.015 0.501 1 0006354 DNA-dependent transcription, elongation P 0 0 0 0 0 2 2 2 100 100 1.395 0.502 1 0032784 regulation of DNA-dependent transcription, elongation P 2 2 2 100 100 2 2 2 100 100 1.395 0.502 1 0004829 threonine-tRNA ligase activity F 0 1 1 0 100 0 1 1 0 100 -1.015 0.502 1 0036009 protein-glutamine N-methyltransferase activity F 0 1 1 0 100 0 1 1 0 100 -1.015 0.502 1 0018364 peptidyl-glutamine methylation P 0 1 1 0 100 0 1 1 0 100 -1.015 0.502 1 0008276 protein methyltransferase activity F 0 1 1 0 100 0 1 1 0 100 -1.015 0.502 1 0006479 protein methylation P 0 1 1 0 100 0 1 1 0 100 -1.015 0.502 1 0008213 protein alkylation P 0 0 0 0 0 0 1 1 0 100 -1.015 0.502 1 0006435 threonyl-tRNA aminoacylation P 0 1 1 0 100 0 1 1 0 100 -1.015 0.502 1 0004591 oxoglutarate dehydrogenase (succinyl-transferring) activity F 0 1 1 0 100 0 1 1 0 100 -1.015 0.502 1 0003866 3-phosphoshikimate 1-carboxyvinyltransferase activity F 0 1 1 0 100 0 1 1 0 100 -1.015 0.502 1 0004655 porphobilinogen synthase activity F 0 1 1 0 100 0 1 1 0 100 -1.015 0.503 1 0043603 cellular amide metabolic process P 0 0 0 0 0 2 2 2 100 100 1.395 0.504 1 0070647 protein modification by small protein conjugation or removal P 0 0 0 0 0 2 2 2 100 100 1.395 0.504 1 0044217 other organism part C 0 0 0 0 0 2 2 2 100 100 1.395 0.504 1 0043657 host cell C 2 2 2 100 100 2 2 2 100 100 1.395 0.504 1 0016579 protein deubiquitination P 2 2 2 100 100 2 2 2 100 100 1.395 0.504 1 0044216 other organism cell C 0 0 0 0 0 2 2 2 100 100 1.395 0.504 1 0043043 peptide biosynthetic process P 2 2 2 100 100 2 2 2 100 100 1.395 0.504 1 0019784 NEDD8-specific protease activity F 2 2 2 100 100 2 2 2 100 100 1.395 0.504 1 0000338 protein deneddylation P 2 2 2 100 100 2 2 2 100 100 1.395 0.504 1 0019783 small conjugating protein-specific protease activity F 0 0 0 0 0 2 2 2 100 100 1.395 0.504 1 0018995 host C 0 0 0 0 0 2 2 2 100 100 1.395 0.504 1 0044215 other organism C 0 0 0 0 0 2 2 2 100 100 1.395 0.504 1 0006518 peptide metabolic process P 0 0 0 0 0 2 2 2 100 100 1.395 0.504 1 0004843 ubiquitin-specific protease activity F 2 2 2 100 100 2 2 2 100 100 1.395 0.504 1 0070646 protein modification by small protein removal P 0 0 0 0 0 2 2 2 100 100 1.395 0.504 1 0043604 amide biosynthetic process P 0 0 0 0 0 2 2 2 100 100 1.395 0.504 1 0043245 extraorganismal space C 0 0 0 0 0 2 2 2 100 100 1.395 0.504 1 0008234 cysteine-type peptidase activity F 2 2 2 100 100 2 2 2 100 100 1.395 0.504 1 0044421 extracellular region part C 0 0 0 0 0 2 2 2 100 100 1.395 0.504 1 0006090 pyruvate metabolic process P 0 1 1 0 100 3 8 8 37.5 100 -0.752 0.504 1 0006515 misfolded or incompletely synthesized protein catabolic process P 0 1 1 0 100 0 1 1 0 100 -1.015 0.504 1 0000906 6,7-dimethyl-8-ribityllumazine synthase activity F 0 1 1 0 100 0 1 1 0 100 -1.015 0.504 1 0003856 3-dehydroquinate synthase activity F 0 1 1 0 100 0 1 1 0 100 -1.015 0.504 1 0009349 riboflavin synthase complex C 0 1 1 0 100 0 1 1 0 100 -1.015 0.504 1 0016867 intramolecular transferase activity, transferring acyl groups F 0 0 0 0 0 0 1 1 0 100 -1.015 0.504 1 0044257 cellular protein catabolic process P 0 0 0 0 0 0 1 1 0 100 -1.015 0.504 1 0051603 proteolysis involved in cellular protein catabolic process P 0 0 0 0 0 0 1 1 0 100 -1.015 0.504 1 0019156 isoamylase activity F 0 1 1 0 100 0 1 1 0 100 -1.015 0.504 1 0006351 transcription, DNA-dependent P 8 15 15 53.33333 100 9 21 21 42.85714 100 -0.733 0.505 1 0008690 3-deoxy-manno-octulosonate cytidylyltransferase activity F 0 1 1 0 100 0 1 1 0 100 -1.015 0.505 1 0033468 CMP-keto-3-deoxy-D-manno-octulosonic acid biosynthetic process P 0 1 1 0 100 0 1 1 0 100 -1.015 0.505 1 0006229 dUTP biosynthetic process P 0 1 1 0 100 0 1 1 0 100 -1.015 0.505 1 0008829 dCTP deaminase activity F 0 1 1 0 100 0 1 1 0 100 -1.015 0.505 1 0046930 pore complex C 0 1 1 0 100 0 1 1 0 100 -1.015 0.505 1 0033467 CMP-keto-3-deoxy-D-manno-octulosonic acid metabolic process P 0 0 0 0 0 0 1 1 0 100 -1.015 0.505 1 0008915 lipid-A-disaccharide synthase activity F 0 1 1 0 100 0 1 1 0 100 -1.015 0.505 1 0004127 cytidylate kinase activity F 0 1 1 0 100 0 1 1 0 100 -1.015 0.505 1 0072593 reactive oxygen species metabolic process P 0 0 0 0 0 2 2 2 100 100 1.395 0.506 1 0006801 superoxide metabolic process P 1 1 1 100 100 2 2 2 100 100 1.395 0.506 1 0019693 ribose phosphate metabolic process P 0 0 0 0 0 18 40 40 45 100 -0.748 0.507 1 0009259 ribonucleotide metabolic process P 0 0 0 0 0 18 40 40 45 100 -0.748 0.507 1 0044210 ’de novo’ CTP biosynthetic process P 2 2 2 100 100 2 2 2 100 100 1.395 0.508 1 0016998 cell wall macromolecule catabolic process P 2 2 2 100 100 2 2 2 100 100 1.395 0.508 1 0003906 DNA-(apurinic or apyrimidinic site) lyase activity F 0 1 1 0 100 0 1 1 0 100 -1.015 0.508 1 0005975 carbohydrate metabolic process P 10 16 16 62.5 100 23 41 41 56.09756 100 0.712 0.509 1 0009338 exodeoxyribonuclease V complex C 0 1 1 0 100 0 1 1 0 100 -1.015 0.509 1 0004619 phosphoglycerate mutase activity F 0 1 1 0 100 0 1 1 0 100 -1.015 0.509 1 0046538 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity F 0 1 1 0 100 0 1 1 0 100 -1.015 0.509 1 0016874 ligase activity F 22 40 40 55 100 23 41 41 56.09756 100 0.712 0.51 1 0016742 hydroxymethyl-, formyl- and related transferase activity F 1 1 1 100 100 2 2 2 100 100 1.395 0.511 1 0016830 carbon-carbon lyase activity F 0 0 0 0 0 6 9 9 66.66666 100 0.963 0.511 1 0031071 cysteine desulfurase activity F 0 1 1 0 100 0 1 1 0 100 -1.015 0.511 1 0001887 selenium compound metabolic process P 0 0 0 0 0 0 1 1 0 100 -1.015 0.511 1 0016260 selenocysteine biosynthetic process P 0 1 1 0 100 0 1 1 0 100 -1.015 0.511 1 0006434 seryl-tRNA aminoacylation P 0 1 1 0 100 0 1 1 0 100 -1.015 0.511 1 0004828 serine-tRNA ligase activity F 0 1 1 0 100 0 1 1 0 100 -1.015 0.511 1 0097056 selenocysteinyl-tRNA(Sec) biosynthetic process P 0 1 1 0 100 0 1 1 0 100 -1.015 0.511 1 0016259 selenocysteine metabolic process P 0 0 0 0 0 0 1 1 0 100 -1.015 0.511 1 0006534 cysteine metabolic process P 0 1 1 0 100 0 1 1 0 100 -1.015 0.511 1 0045252 oxoglutarate dehydrogenase complex C 0 1 1 0 100 0 1 1 0 100 -1.015 0.512 1 0016751 S-succinyltransferase activity F 0 0 0 0 0 0 1 1 0 100 -1.015 0.512 1 0008765 UDP-N-acetylmuramoylalanyl-D-glutamate-2,6-diaminopimelate ligase activity F 0 1 1 0 100 0 1 1 0 100 -1.015 0.512 1 0016748 succinyltransferase activity F 0 0 0 0 0 0 1 1 0 100 -1.015 0.512 1 0009029 tetraacyldisaccharide 4’-kinase activity F 0 1 1 0 100 0 1 1 0 100 -1.015 0.512 1 0045240 dihydrolipoyl dehydrogenase complex C 0 0 0 0 0 0 1 1 0 100 -1.015 0.512 1 0004149 dihydrolipoyllysine-residue succinyltransferase activity F 0 1 1 0 100 0 1 1 0 100 -1.015 0.512 1 0016798 hydrolase activity, acting on glycosyl bonds F 2 7 7 28.57143 100 3 8 8 37.5 100 -0.752 0.513 1 0009189 deoxyribonucleoside diphosphate biosynthetic process P 0 0 0 0 0 0 1 1 0 100 -1.015 0.513 1 0009139 pyrimidine nucleoside diphosphate biosynthetic process P 0 0 0 0 0 0 1 1 0 100 -1.015 0.513 1 0009196 pyrimidine deoxyribonucleoside diphosphate metabolic process P 0 0 0 0 0 0 1 1 0 100 -1.015 0.513 1 0009197 pyrimidine deoxyribonucleoside diphosphate biosynthetic process P 0 0 0 0 0 0 1 1 0 100 -1.015 0.513 1 0009133 nucleoside diphosphate biosynthetic process P 0 0 0 0 0 0 1 1 0 100 -1.015 0.513 1 0009138 pyrimidine nucleoside diphosphate metabolic process P 0 0 0 0 0 0 1 1 0 100 -1.015 0.513 1 0008965 phosphoenolpyruvate-protein phosphotransferase activity F 0 1 1 0 100 0 1 1 0 100 -1.015 0.513 1 0046072 dTDP metabolic process P 0 0 0 0 0 0 1 1 0 100 -1.015 0.513 1 0046075 dTTP metabolic process P 0 0 0 0 0 0 1 1 0 100 -1.015 0.513 1 0033818 beta-ketoacyl-acyl-carrier-protein synthase III activity F 0 1 1 0 100 0 1 1 0 100 -1.015 0.513 1 0003919 FMN adenylyltransferase activity F 0 1 1 0 100 0 1 1 0 100 -1.015 0.513 1 0004315 3-oxoacyl-[acyl-carrier-protein] synthase activity F 0 1 1 0 100 0 1 1 0 100 -1.015 0.513 1 0006235 dTTP biosynthetic process P 0 1 1 0 100 0 1 1 0 100 -1.015 0.513 1 0008531 riboflavin kinase activity F 0 1 1 0 100 0 1 1 0 100 -1.015 0.513 1 0006233 dTDP biosynthetic process P 0 1 1 0 100 0 1 1 0 100 -1.015 0.513 1 0004798 thymidylate kinase activity F 0 1 1 0 100 0 1 1 0 100 -1.015 0.513 1 0004107 chorismate synthase activity F 0 1 1 0 100 0 1 1 0 100 -1.015 0.515 1 0070180 LSU rRNA binding F 2 2 2 100 100 2 2 2 100 100 1.395 0.516 1 0022610 biological adhesion P 0 0 0 0 0 2 2 2 100 100 1.395 0.516 1 0007155 cell adhesion P 2 2 2 100 100 2 2 2 100 100 1.395 0.516 1 0016741 transferase activity, transferring one-carbon groups F 0 0 0 0 0 8 19 19 42.10526 100 -0.762 0.516 1 0052381 tRNA dimethylallyltransferase activity F 0 1 1 0 100 0 1 1 0 100 -1.015 0.516 1 0004366 glycerol-3-phosphate O-acyltransferase activity F 0 1 1 0 100 0 1 1 0 100 -1.015 0.516 1 0006996 organelle organization P 0 0 0 0 0 2 2 2 100 100 1.395 0.517 1 0043414 macromolecule methylation P 0 0 0 0 0 3 8 8 37.5 100 -0.752 0.517 1 0043231 intracellular membrane-bounded organelle C 0 1 1 0 100 0 1 1 0 100 -1.015 0.517 1 0043227 membrane-bounded organelle C 0 0 0 0 0 0 1 1 0 100 -1.015 0.517 1 0019877 diaminopimelate biosynthetic process P 2 2 2 100 100 2 2 2 100 100 1.395 0.52 1 0015804 neutral amino acid transport P 0 0 0 0 0 2 2 2 100 100 1.395 0.52 1 0005416 cation:amino acid symporter activity F 0 0 0 0 0 2 2 2 100 100 1.395 0.52 1 0005294 neutral L-amino acid secondary active transmembrane transporter activity F 0 0 0 0 0 2 2 2 100 100 1.395 0.52 1 0015175 neutral amino acid transmembrane transporter activity F 0 0 0 0 0 2 2 2 100 100 1.395 0.52 1 0022858 alanine transmembrane transporter activity F 0 0 0 0 0 2 2 2 100 100 1.395 0.52 1 0005283 sodium:amino acid symporter activity F 0 0 0 0 0 2 2 2 100 100 1.395 0.52 1 0015655 alanine:sodium symporter activity F 2 2 2 100 100 2 2 2 100 100 1.395 0.52 1 0032328 alanine transport P 2 2 2 100 100 2 2 2 100 100 1.395 0.52 1 0050515 4-(cytidine 5’-diphospho)-2-C-methyl-D-erythritol kinase activity F 0 1 1 0 100 0 1 1 0 100 -1.015 0.521 1 0008963 phospho-N-acetylmuramoyl-pentapeptide-transferase activity F 0 1 1 0 100 0 1 1 0 100 -1.015 0.521 1 0051992 UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-meso-2,6-diaminopimelyl-D-alanyl-D-alanine:undecaprenyl-phosphate transferase activity F 0 1 1 0 100 0 1 1 0 100 -1.015 0.521 1 0019521 D-gluconate metabolic process P 0 1 1 0 100 0 1 1 0 100 -1.015 0.523 1 0019520 aldonic acid metabolic process P 0 0 0 0 0 0 1 1 0 100 -1.015 0.523 1 0004616 phosphogluconate dehydrogenase (decarboxylating) activity F 0 1 1 0 100 0 1 1 0 100 -1.015 0.523 1 0004853 uroporphyrinogen decarboxylase activity F 0 1 1 0 100 0 1 1 0 100 -1.015 0.523 1 0042451 purine nucleoside biosynthetic process P 0 0 0 0 0 4 10 10 40 100 -0.683 0.527 1 0046129 purine ribonucleoside biosynthetic process P 0 0 0 0 0 4 10 10 40 100 -0.683 0.527 1 0009152 purine ribonucleotide biosynthetic process P 0 0 0 0 0 4 10 10 40 100 -0.683 0.527 1 0002097 tRNA wobble base modification P 0 0 0 0 0 0 1 1 0 100 -1.015 0.529 1 0045254 pyruvate dehydrogenase complex C 0 1 1 0 100 0 1 1 0 100 -1.015 0.529 1 0002098 tRNA wobble uridine modification P 0 1 1 0 100 0 1 1 0 100 -1.015 0.529 1 0016418 S-acetyltransferase activity F 0 0 0 0 0 0 1 1 0 100 -1.015 0.529 1 0004742 dihydrolipoyllysine-residue acetyltransferase activity F 0 1 1 0 100 0 1 1 0 100 -1.015 0.529 1 0030523 dihydrolipoamide S-acyltransferase activity F 0 0 0 0 0 0 1 1 0 100 -1.015 0.529 1 1901137 carbohydrate derivative biosynthetic process P 0 0 0 0 0 18 40 40 45 100 -0.748 0.531 1 0046942 carboxylic acid transport P 0 0 0 0 0 7 11 12 63.63636 91.66666 0.864 0.532 1 0015711 organic anion transport P 0 0 0 0 0 7 11 12 63.63636 91.66666 0.864 0.532 1 0015849 organic acid transport P 0 0 0 0 0 7 11 12 63.63636 91.66666 0.864 0.532 1 0050661 NADP binding F 4 9 9 44.44444 100 4 10 10 40 100 -0.683 0.533 1 0015658 branched-chain amino acid transmembrane transporter activity F 0 1 1 0 100 0 1 1 0 100 -1.015 0.534 1 0015803 branched-chain amino acid transport P 0 1 1 0 100 0 1 1 0 100 -1.015 0.534 1 0004605 phosphatidate cytidylyltransferase activity F 0 1 1 0 100 0 1 1 0 100 -1.015 0.536 1 0047429 nucleoside-triphosphate diphosphatase activity F 1 1 1 100 100 2 2 2 100 100 1.395 0.537 1 0016070 RNA metabolic process P 0 2 2 0 100 37 78 79 47.4359 98.73418 -0.62 0.542 1 1901293 nucleoside phosphate biosynthetic process P 0 0 0 0 0 10 23 23 43.47826 100 -0.708 0.548 1 0009165 nucleotide biosynthetic process P 1 3 3 33.33333 100 10 23 23 43.47826 100 -0.708 0.548 1 0006414 translational elongation P 4 6 6 66.66666 100 7 11 11 63.63636 100 0.864 0.549 1 0046872 metal ion binding F 41 73 73 56.16438 100 45 83 83 54.21687 100 0.683 0.551 1 1901564 organonitrogen compound metabolic process P 0 0 0 0 0 62 129 130 48.06202 99.23077 -0.678 0.551 1 0016651 oxidoreductase activity, acting on NAD(P)H F 0 0 0 0 0 4 10 10 40 100 -0.683 0.554 1 0016866 intramolecular transferase activity F 0 1 1 0 100 7 11 12 63.63636 91.66666 0.864 0.561 1 0051186 cofactor metabolic process P 0 0 0 0 0 13 29 29 44.82759 100 -0.65 0.563 1 0016627 oxidoreductase activity, acting on the CH-CH group of donors F 0 0 0 0 0 4 10 10 40 100 -0.683 0.563 1 0019001 guanyl nucleotide binding F 0 0 0 0 0 8 13 13 61.53846 100 0.788 0.583 1 0032561 guanyl ribonucleotide binding F 0 0 0 0 0 8 13 13 61.53846 100 0.788 0.583 1 0005525 GTP binding F 8 13 13 61.53846 100 8 13 13 61.53846 100 0.788 0.583 1 0044723 single-organism carbohydrate metabolic process P 0 0 0 0 0 18 32 32 56.25 100 0.642 0.586 1 0004527 exonuclease activity F 2 6 6 33.33333 100 6 14 14 42.85714 100 -0.595 0.589 1 1901677 phosphate transmembrane transporter activity F 0 0 0 0 0 1 3 3 33.33333 100 -0.603 0.589 1 0006820 anion transport P 0 0 0 0 0 8 13 14 61.53846 92.85714 0.788 0.591 1 0044765 single-organism transport P 0 0 0 0 0 29 62 63 46.77419 98.4127 -0.655 0.592 1 1901565 organonitrogen compound catabolic process P 0 0 0 0 0 14 31 31 45.16129 100 -0.635 0.593 1 0016071 mRNA metabolic process P 0 0 0 0 0 1 3 3 33.33333 100 -0.603 0.596 1 0043241 protein complex disassembly P 0 0 0 0 0 3 4 5 75 80 0.974 0.6 1 0032984 macromolecular complex disassembly P 0 0 0 0 0 3 4 5 75 80 0.974 0.6 1 0022411 cellular component disassembly P 0 0 0 0 0 3 4 5 75 80 0.974 0.6 1 0016835 carbon-oxygen lyase activity F 0 0 0 0 0 6 14 16 42.85714 87.5 -0.595 0.6 1 0015144 carbohydrate transmembrane transporter activity F 0 0 0 0 0 1 3 3 33.33333 100 -0.603 0.6 1 0016884 carbon-nitrogen ligase activity, with glutamine as amido-N-donor F 1 2 2 50 100 1 3 3 33.33333 100 -0.603 0.6 1 1901476 carbohydrate transporter activity F 0 0 0 0 0 1 3 3 33.33333 100 -0.603 0.6 1 0009144 purine nucleoside triphosphate metabolic process P 0 0 0 0 0 15 33 33 45.45454 100 -0.621 0.602 1 0009205 purine ribonucleoside triphosphate metabolic process P 0 0 0 0 0 15 33 33 45.45454 100 -0.621 0.602 1 1901607 alpha-amino acid biosynthetic process P 0 0 0 0 0 9 15 16 60 93.75 0.727 0.603 1 0017169 CDP-alcohol phosphatidyltransferase activity F 0 0 0 0 0 1 3 3 33.33333 100 -0.603 0.603 1 0006040 amino sugar metabolic process P 0 0 0 0 0 1 3 3 33.33333 100 -0.603 0.603 1 0046349 amino sugar biosynthetic process P 0 0 0 0 0 1 3 3 33.33333 100 -0.603 0.603 1 0042559 pteridine-containing compound biosynthetic process P 0 0 0 0 0 1 3 3 33.33333 100 -0.603 0.604 1 0009396 folic acid-containing compound biosynthetic process P 1 3 3 33.33333 100 1 3 3 33.33333 100 -0.603 0.604 1 0009116 nucleoside metabolic process P 1 1 1 100 100 20 43 43 46.51163 100 -0.572 0.605 1 1901657 glycosyl compound metabolic process P 0 0 0 0 0 20 43 43 46.51163 100 -0.572 0.605 1 0009309 amine biosynthetic process P 0 0 0 0 0 1 3 4 33.33333 75 -0.603 0.605 1 0044106 cellular amine metabolic process P 0 0 0 0 0 1 3 4 33.33333 75 -0.603 0.605 1 0006576 cellular biogenic amine metabolic process P 0 0 0 0 0 1 3 4 33.33333 75 -0.603 0.605 1 0006586 indolalkylamine metabolic process P 0 0 0 0 0 1 3 4 33.33333 75 -0.603 0.605 1 0042430 indole-containing compound metabolic process P 0 0 0 0 0 1 3 4 33.33333 75 -0.603 0.605 1 0042435 indole-containing compound biosynthetic process P 0 0 0 0 0 1 3 4 33.33333 75 -0.603 0.605 1 0009308 amine metabolic process P 0 0 0 0 0 1 3 4 33.33333 75 -0.603 0.605 1 0042401 cellular biogenic amine biosynthetic process P 0 0 0 0 0 1 3 4 33.33333 75 -0.603 0.605 1 0006568 tryptophan metabolic process P 1 3 3 33.33333 100 1 3 4 33.33333 75 -0.603 0.605 1 0000162 tryptophan biosynthetic process P 1 3 4 33.33333 75 1 3 4 33.33333 75 -0.603 0.605 1 0046219 indolalkylamine biosynthetic process P 0 0 0 0 0 1 3 4 33.33333 75 -0.603 0.605 1 0006508 proteolysis P 12 21 21 57.14286 100 12 21 21 57.14286 100 0.598 0.606 1 0006399 tRNA metabolic process P 0 0 0 0 0 21 38 39 55.26316 97.4359 0.577 0.606 1 0016791 phosphatase activity F 0 0 0 0 0 1 3 3 33.33333 100 -0.603 0.607 1 0016620 oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor F 1 2 2 50 100 1 3 3 33.33333 100 -0.603 0.609 1 0003333 amino acid transmembrane transport P 3 4 5 75 80 3 4 5 75 80 0.974 0.61 1 0046501 protoporphyrinogen IX metabolic process P 0 0 0 0 0 1 3 3 33.33333 100 -0.603 0.61 1 0006782 protoporphyrinogen IX biosynthetic process P 1 3 3 33.33333 100 1 3 3 33.33333 100 -0.603 0.61 1 0070567 cytidylyltransferase activity F 0 0 0 0 0 1 3 3 33.33333 100 -0.603 0.61 1 0031167 rRNA methylation P 1 2 2 50 100 1 3 3 33.33333 100 -0.603 0.614 1 0008235 metalloexopeptidase activity F 1 3 3 33.33333 100 1 3 3 33.33333 100 -0.603 0.614 1 0000154 rRNA modification P 0 1 1 0 100 1 3 3 33.33333 100 -0.603 0.614 1 0005694 chromosome C 3 3 3 100 100 3 4 4 75 100 0.974 0.615 1 0008144 drug binding F 0 0 0 0 0 1 3 3 33.33333 100 -0.603 0.615 1 0019319 hexose biosynthetic process P 0 0 0 0 0 1 3 3 33.33333 100 -0.603 0.616 1 0006094 gluconeogenesis P 1 3 3 33.33333 100 1 3 3 33.33333 100 -0.603 0.616 1 0007049 cell cycle P 6 14 14 42.85714 100 6 14 14 42.85714 100 -0.595 0.617 1 0008324 cation transmembrane transporter activity F 1 1 1 100 100 7 16 16 43.75 100 -0.565 0.618 1 0003674 molecular_function F 0 0 0 0 0 287 561 564 51.15865 99.46809 0.655 0.619 1 0016051 carbohydrate biosynthetic process P 1 1 1 100 100 10 17 17 58.82353 100 0.677 0.62 1 0044802 single-organism membrane organization P 0 0 0 0 0 3 4 4 75 100 0.974 0.622 1 0061024 membrane organization P 0 0 0 0 0 3 4 4 75 100 0.974 0.622 1 0004553 hydrolase activity, hydrolyzing O-glycosyl compounds F 1 2 2 50 100 1 3 3 33.33333 100 -0.603 0.624 1 0042886 amide transport P 0 0 0 0 0 3 4 4 75 100 0.974 0.625 1 0006468 protein phosphorylation P 1 3 3 33.33333 100 1 3 3 33.33333 100 -0.603 0.625 1 0015672 monovalent inorganic cation transport P 0 0 0 0 0 7 16 16 43.75 100 -0.565 0.626 1 0016769 transferase activity, transferring nitrogenous groups F 0 0 0 0 0 3 4 4 75 100 0.974 0.628 1 0008483 transaminase activity F 3 4 4 75 100 3 4 4 75 100 0.974 0.628 1 0016634 oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor F 0 0 0 0 0 1 3 3 33.33333 100 -0.603 0.63 1 0009220 pyrimidine ribonucleotide biosynthetic process P 0 1 1 0 100 3 4 4 75 100 0.974 0.631 1 0009218 pyrimidine ribonucleotide metabolic process P 0 0 0 0 0 3 4 4 75 100 0.974 0.631 1 0033866 nucleoside bisphosphate biosynthetic process P 0 0 0 0 0 1 3 3 33.33333 100 -0.603 0.631 1 0015937 coenzyme A biosynthetic process P 0 1 1 0 100 1 3 3 33.33333 100 -0.603 0.631 1 0033875 ribonucleoside bisphosphate metabolic process P 0 0 0 0 0 1 3 3 33.33333 100 -0.603 0.631 1 0034033 purine nucleoside bisphosphate biosynthetic process P 0 0 0 0 0 1 3 3 33.33333 100 -0.603 0.631 1 0034032 purine nucleoside bisphosphate metabolic process P 0 0 0 0 0 1 3 3 33.33333 100 -0.603 0.631 1 0033865 nucleoside bisphosphate metabolic process P 0 0 0 0 0 1 3 3 33.33333 100 -0.603 0.631 1 0015936 coenzyme A metabolic process P 0 0 0 0 0 1 3 3 33.33333 100 -0.603 0.631 1 0034030 ribonucleoside bisphosphate biosynthetic process P 0 0 0 0 0 1 3 3 33.33333 100 -0.603 0.631 1 0061505 DNA topoisomerase II activity F 0 0 0 0 0 3 4 4 75 100 0.974 0.632 1 0003918 DNA topoisomerase type II (ATP-hydrolyzing) activity F 3 4 4 75 100 3 4 4 75 100 0.974 0.632 1 0043169 cation binding F 1 2 2 50 100 46 86 86 53.48837 100 0.552 0.633 1 0016417 S-acyltransferase activity F 0 0 0 0 0 1 3 3 33.33333 100 -0.603 0.633 1 0006413 translational initiation P 3 4 4 75 100 3 4 4 75 100 0.974 0.635 1 0016799 hydrolase activity, hydrolyzing N-glycosyl compounds F 0 1 1 0 100 1 3 3 33.33333 100 -0.603 0.635 1 0009211 pyrimidine deoxyribonucleoside triphosphate metabolic process P 0 0 0 0 0 1 3 3 33.33333 100 -0.603 0.637 1 0009200 deoxyribonucleoside triphosphate metabolic process P 0 0 0 0 0 1 3 3 33.33333 100 -0.603 0.637 1 0016881 acid-amino acid ligase activity F 0 1 1 0 100 3 4 4 75 100 0.974 0.639 1 0002161 aminoacyl-tRNA editing activity F 3 4 4 75 100 3 4 4 75 100 0.974 0.642 1 0004312 fatty acid synthase activity F 0 0 0 0 0 3 4 4 75 100 0.974 0.643 1 0008654 phospholipid biosynthetic process P 1 6 6 16.66667 100 8 18 18 44.44444 100 -0.54 0.643 1 0065002 intracellular protein transmembrane transport P 3 4 4 75 100 3 4 4 75 100 0.974 0.644 1 0009132 nucleoside diphosphate metabolic process P 0 0 0 0 0 1 3 3 33.33333 100 -0.603 0.645 1 0004659 prenyltransferase activity F 0 2 2 0 100 1 3 3 33.33333 100 -0.603 0.648 1 0005343 organic acid:sodium symporter activity F 0 0 0 0 0 3 4 4 75 100 0.974 0.653 1 0015296 anion:cation symporter activity F 0 0 0 0 0 3 4 4 75 100 0.974 0.653 1 0000160 phosphorelay signal transduction system P 1 3 3 33.33333 100 1 3 3 33.33333 100 -0.603 0.655 1 0003746 translation elongation factor activity F 4 6 6 66.66666 100 4 6 6 66.66666 100 0.784 0.661 1 0046364 monosaccharide biosynthetic process P 0 0 0 0 0 2 5 5 40 100 -0.481 0.664 1 0006644 phospholipid metabolic process P 0 1 1 0 100 9 20 20 45 100 -0.52 0.664 1 1901575 organic substance catabolic process P 0 0 0 0 0 26 55 55 47.27273 100 -0.535 0.665 1 1901605 alpha-amino acid metabolic process P 0 0 0 0 0 12 21 22 57.14286 95.45454 0.598 0.668 1 0006754 ATP biosynthetic process P 2 5 5 40 100 2 5 5 40 100 -0.481 0.671 1 0043566 structure-specific DNA binding F 0 0 0 0 0 2 5 5 40 100 -0.481 0.671 1 0044769 ATPase activity, coupled to transmembrane movement of ions, rotational mechanism F 0 0 0 0 0 2 5 5 40 100 -0.481 0.671 1 0015171 amino acid transmembrane transporter activity F 1 2 2 50 100 4 6 6 66.66666 100 0.784 0.679 1 0016831 carboxy-lyase activity F 2 5 5 40 100 2 5 5 40 100 -0.481 0.679 1 0004222 metalloendopeptidase activity F 2 5 5 40 100 2 5 5 40 100 -0.481 0.68 1 0009069 serine family amino acid metabolic process P 0 0 0 0 0 2 5 5 40 100 -0.481 0.68 1 0016725 oxidoreductase activity, acting on CH or CH2 groups F 0 0 0 0 0 2 5 5 40 100 -0.481 0.681 1 0051649 establishment of localization in cell P 0 0 0 0 0 10 22 22 45.45454 100 -0.503 0.686 1 1901271 lipooligosaccharide biosynthetic process P 0 0 0 0 0 4 6 6 66.66666 100 0.784 0.688 1 0006664 glycolipid metabolic process P 0 0 0 0 0 4 6 6 66.66666 100 0.784 0.688 1 1901269 lipooligosaccharide metabolic process P 0 0 0 0 0 4 6 6 66.66666 100 0.784 0.688 1 0006643 membrane lipid metabolic process P 0 0 0 0 0 4 6 6 66.66666 100 0.784 0.688 1 0046467 membrane lipid biosynthetic process P 0 0 0 0 0 4 6 6 66.66666 100 0.784 0.688 1 0009247 glycolipid biosynthetic process P 0 0 0 0 0 4 6 6 66.66666 100 0.784 0.688 1 0009245 lipid A biosynthetic process P 4 6 6 66.66666 100 4 6 6 66.66666 100 0.784 0.688 1 0046493 lipid A metabolic process P 0 0 0 0 0 4 6 6 66.66666 100 0.784 0.688 1 0022891 substrate-specific transmembrane transporter activity F 0 0 0 0 0 12 26 26 46.15385 100 -0.476 0.688 1 0016780 phosphotransferase activity, for other substituted phosphate groups F 1 3 3 33.33333 100 2 5 5 40 100 -0.481 0.69 1 0046873 metal ion transmembrane transporter activity F 0 0 0 0 0 4 6 6 66.66666 100 0.784 0.692 1 0016776 phosphotransferase activity, phosphate group as acceptor F 0 1 1 0 100 2 5 5 40 100 -0.481 0.695 1 0009147 pyrimidine nucleoside triphosphate metabolic process P 0 0 0 0 0 4 6 6 66.66666 100 0.784 0.697 1 0009279 cell outer membrane C 4 6 6 66.66666 100 4 6 6 66.66666 100 0.784 0.697 1 0044462 external encapsulating structure part C 0 0 0 0 0 4 6 6 66.66666 100 0.784 0.697 1 0043933 macromolecular complex subunit organization P 0 0 0 0 0 4 6 7 66.66666 85.71429 0.784 0.701 1 0009263 deoxyribonucleotide biosynthetic process P 0 1 1 0 100 2 5 5 40 100 -0.481 0.706 1 0009262 deoxyribonucleotide metabolic process P 0 0 0 0 0 2 5 5 40 100 -0.481 0.706 1 0022892 substrate-specific transporter activity F 0 0 0 0 0 13 28 28 46.42857 100 -0.465 0.707 1 0044265 cellular macromolecule catabolic process P 0 0 0 0 0 3 7 7 42.85714 100 -0.418 0.713 1 0006721 terpenoid metabolic process P 0 0 0 0 0 3 7 7 42.85714 100 -0.418 0.718 1 0016114 terpenoid biosynthetic process P 3 7 7 42.85714 100 3 7 7 42.85714 100 -0.418 0.718 1 0006865 amino acid transport P 1 3 3 33.33333 100 5 8 9 62.5 88.88889 0.67 0.719 1 1901136 carbohydrate derivative catabolic process P 0 0 0 0 0 14 30 30 46.66667 100 -0.455 0.719 1 0015293 symporter activity F 0 2 2 0 100 3 7 7 42.85714 100 -0.418 0.721 1 0015294 solute:cation symporter activity F 0 0 0 0 0 3 7 7 42.85714 100 -0.418 0.721 1 0015992 proton transport P 2 5 5 40 100 3 7 7 42.85714 100 -0.418 0.722 1 0006818 hydrogen transport P 0 0 0 0 0 3 7 7 42.85714 100 -0.418 0.722 1 0015078 hydrogen ion transmembrane transporter activity F 1 2 2 50 100 3 7 7 42.85714 100 -0.418 0.722 1 0009201 ribonucleoside triphosphate biosynthetic process P 0 0 0 0 0 5 8 8 62.5 100 0.67 0.726 1 0071806 protein transmembrane transport P 0 0 0 0 0 5 8 8 62.5 100 0.67 0.728 1 0034061 DNA polymerase activity F 0 0 0 0 0 3 7 7 42.85714 100 -0.418 0.729 1 0003887 DNA-directed DNA polymerase activity F 3 7 7 42.85714 100 3 7 7 42.85714 100 -0.418 0.729 1 0046434 organophosphate catabolic process P 0 0 0 0 0 14 30 30 46.66667 100 -0.455 0.73 1 0051246 regulation of protein metabolic process P 0 0 0 0 0 5 8 8 62.5 100 0.67 0.732 1 0006417 regulation of translation P 2 2 2 100 100 5 8 8 62.5 100 0.67 0.732 1 0010608 posttranscriptional regulation of gene expression P 0 0 0 0 0 5 8 8 62.5 100 0.67 0.732 1 0032268 regulation of cellular protein metabolic process P 0 0 0 0 0 5 8 8 62.5 100 0.67 0.732 1 0006195 purine nucleotide catabolic process P 0 0 0 0 0 13 28 28 46.42857 100 -0.465 0.733 1 0009146 purine nucleoside triphosphate catabolic process P 0 0 0 0 0 13 28 28 46.42857 100 -0.465 0.733 1 0006152 purine nucleoside catabolic process P 0 0 0 0 0 13 28 28 46.42857 100 -0.465 0.733 1 0072523 purine-containing compound catabolic process P 0 0 0 0 0 13 28 28 46.42857 100 -0.465 0.733 1 0009166 nucleotide catabolic process P 0 0 0 0 0 13 28 28 46.42857 100 -0.465 0.733 1 0042454 ribonucleoside catabolic process P 0 0 0 0 0 13 28 28 46.42857 100 -0.465 0.733 1 0046130 purine ribonucleoside catabolic process P 0 0 0 0 0 13 28 28 46.42857 100 -0.465 0.733 1 1901658 glycosyl compound catabolic process P 0 0 0 0 0 13 28 28 46.42857 100 -0.465 0.733 1 0009203 ribonucleoside triphosphate catabolic process P 0 0 0 0 0 13 28 28 46.42857 100 -0.465 0.733 1 0009207 purine ribonucleoside triphosphate catabolic process P 0 0 0 0 0 13 28 28 46.42857 100 -0.465 0.733 1 0009154 purine ribonucleotide catabolic process P 0 0 0 0 0 13 28 28 46.42857 100 -0.465 0.733 1 0009261 ribonucleotide catabolic process P 0 0 0 0 0 13 28 28 46.42857 100 -0.465 0.733 1 0009164 nucleoside catabolic process P 0 0 0 0 0 13 28 28 46.42857 100 -0.465 0.733 1 0046039 GTP metabolic process P 0 0 0 0 0 6 10 10 60 100 0.591 0.738 1 1901068 guanosine-containing compound metabolic process P 0 0 0 0 0 6 10 10 60 100 0.591 0.738 1 0071840 cellular component organization or biogenesis P 0 0 0 0 0 21 39 40 53.84615 97.5 0.403 0.739 1 0006733 oxidoreduction coenzyme metabolic process P 0 0 0 0 0 5 8 8 62.5 100 0.67 0.74 1 0005342 organic acid transmembrane transporter activity F 0 0 0 0 0 5 8 8 62.5 100 0.67 0.741 1 0046943 carboxylic acid transmembrane transporter activity F 0 0 0 0 0 5 8 8 62.5 100 0.67 0.741 1 0030170 pyridoxal phosphate binding F 4 9 9 44.44444 100 4 9 9 44.44444 100 -0.379 0.744 1 0072528 pyrimidine-containing compound biosynthetic process P 0 0 0 0 0 5 8 8 62.5 100 0.67 0.746 1 0006814 sodium ion transport P 4 9 9 44.44444 100 4 9 9 44.44444 100 -0.379 0.746 1 0008173 RNA methyltransferase activity F 2 3 3 66.66666 100 3 7 7 42.85714 100 -0.418 0.747 1 0001510 RNA methylation P 2 3 3 66.66666 100 3 7 7 42.85714 100 -0.418 0.748 1 0006023 aminoglycan biosynthetic process P 0 0 0 0 0 4 9 9 44.44444 100 -0.379 0.75 1 0006024 glycosaminoglycan biosynthetic process P 0 0 0 0 0 4 9 9 44.44444 100 -0.379 0.75 1 0070589 cellular component macromolecule biosynthetic process P 0 0 0 0 0 4 9 9 44.44444 100 -0.379 0.75 1 0042546 cell wall biogenesis P 0 0 0 0 0 4 9 9 44.44444 100 -0.379 0.75 1 0009273 peptidoglycan-based cell wall biogenesis P 0 0 0 0 0 4 9 9 44.44444 100 -0.379 0.75 1 0009252 peptidoglycan biosynthetic process P 4 9 9 44.44444 100 4 9 9 44.44444 100 -0.379 0.75 1 0044038 cell wall macromolecule biosynthetic process P 0 0 0 0 0 4 9 9 44.44444 100 -0.379 0.75 1 0009124 nucleoside monophosphate biosynthetic process P 0 0 0 0 0 4 9 9 44.44444 100 -0.379 0.755 1 0044283 small molecule biosynthetic process P 0 0 0 0 0 23 43 44 53.48837 97.72727 0.376 0.756 1 0044711 single-organism biosynthetic process P 0 0 0 0 0 23 43 44 53.48837 97.72727 0.376 0.756 1 0009405 pathogenesis P 5 11 11 45.45454 100 5 11 11 45.45454 100 -0.352 0.757 1 0051704 multi-organism process P 0 0 0 0 0 5 11 11 45.45454 100 -0.352 0.757 1 0015980 energy derivation by oxidation of organic compounds P 0 0 0 0 0 5 11 11 45.45454 100 -0.352 0.76 1 0009108 coenzyme biosynthetic process P 0 0 0 0 0 5 11 11 45.45454 100 -0.352 0.762 1 0050660 flavin adenine dinucleotide binding F 4 9 9 44.44444 100 4 9 9 44.44444 100 -0.379 0.762 1 0008237 metallopeptidase activity F 3 3 3 100 100 4 9 9 44.44444 100 -0.379 0.765 1 0006220 pyrimidine nucleotide metabolic process P 1 2 2 50 100 5 8 8 62.5 100 0.67 0.769 1 0016879 ligase activity, forming carbon-nitrogen bonds F 0 1 1 0 100 8 14 14 57.14286 100 0.486 0.771 1 0016810 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds F 0 2 2 0 100 4 9 9 44.44444 100 -0.379 0.772 1 0008509 anion transmembrane transporter activity F 0 0 0 0 0 5 11 11 45.45454 100 -0.352 0.777 1 0051128 regulation of cellular component organization P 0 0 0 0 0 6 13 13 46.15385 100 -0.333 0.78 1 0030001 metal ion transport P 2 2 2 100 100 7 12 12 58.33333 100 0.532 0.785 1 0008360 regulation of cell shape P 5 11 11 45.45454 100 5 11 11 45.45454 100 -0.352 0.785 1 0022604 regulation of cell morphogenesis P 0 0 0 0 0 5 11 11 45.45454 100 -0.352 0.785 1 0022603 regulation of anatomical structure morphogenesis P 0 0 0 0 0 5 11 11 45.45454 100 -0.352 0.785 1 0050793 regulation of developmental process P 0 0 0 0 0 5 11 11 45.45454 100 -0.352 0.785 1 0046390 ribose phosphate biosynthetic process P 0 0 0 0 0 6 13 13 46.15385 100 -0.333 0.795 1 0009260 ribonucleotide biosynthetic process P 0 0 0 0 0 6 13 13 46.15385 100 -0.333 0.795 1 0006732 coenzyme metabolic process P 0 0 0 0 0 11 20 20 55 100 0.389 0.797 1 0051301 cell division P 6 13 13 46.15385 100 6 13 13 46.15385 100 -0.333 0.797 1 0009163 nucleoside biosynthetic process P 0 0 0 0 0 6 13 13 46.15385 100 -0.333 0.798 1 1901659 glycosyl compound biosynthetic process P 0 0 0 0 0 6 13 13 46.15385 100 -0.333 0.798 1 0042455 ribonucleoside biosynthetic process P 0 0 0 0 0 6 13 13 46.15385 100 -0.333 0.798 1 0006007 glucose catabolic process P 0 0 0 0 0 7 15 15 46.66667 100 -0.318 0.801 1 0019320 hexose catabolic process P 0 0 0 0 0 7 15 15 46.66667 100 -0.318 0.801 1 0046365 monosaccharide catabolic process P 0 0 0 0 0 7 15 15 46.66667 100 -0.318 0.801 1 0044724 single-organism carbohydrate catabolic process P 0 0 0 0 0 7 15 15 46.66667 100 -0.318 0.801 1 0070011 peptidase activity, acting on L-amino acid peptides F 0 0 0 0 0 12 22 22 54.54546 100 0.365 0.812 1 0008270 zinc ion binding F 9 19 19 47.36842 100 9 19 19 47.36842 100 -0.297 0.821 1 0009451 RNA modification P 3 5 6 60 83.33334 12 22 23 54.54546 95.65218 0.365 0.836 1 0033036 macromolecule localization P 0 0 0 0 0 13 27 27 48.14815 100 -0.273 0.84 1 0008104 protein localization P 0 0 0 0 0 13 27 27 48.14815 100 -0.273 0.84 1 0015031 protein transport P 6 11 11 54.54546 100 13 27 27 48.14815 100 -0.273 0.84 1 0045184 establishment of protein localization P 0 0 0 0 0 13 27 27 48.14815 100 -0.273 0.84 1 0055085 transmembrane transport P 1 5 5 20 100 11 23 24 47.82609 95.83334 -0.283 0.84 1 0032787 monocarboxylic acid metabolic process P 0 0 0 0 0 12 22 22 54.54546 100 0.365 0.845 1 0009199 ribonucleoside triphosphate metabolic process P 0 0 0 0 0 17 35 35 48.57143 100 -0.262 0.846 1 0016829 lyase activity F 12 26 28 46.15385 92.85714 14 29 31 48.27586 93.54839 -0.27 0.848 1 0043412 macromolecule modification P 0 0 0 0 0 19 36 37 52.77778 97.29729 0.254 0.85 1 0009141 nucleoside triphosphate metabolic process P 0 0 0 0 0 19 39 39 48.71795 100 -0.258 0.854 1 0044248 cellular catabolic process P 0 0 0 0 0 19 39 39 48.71795 100 -0.258 0.855 1 0008610 lipid biosynthetic process P 1 2 2 50 100 18 34 34 52.94118 100 0.266 0.857 1 1901361 organic cyclic compound catabolic process P 0 0 0 0 0 17 35 35 48.57143 100 -0.262 0.858 1 0046700 heterocycle catabolic process P 0 0 0 0 0 17 35 35 48.57143 100 -0.262 0.858 1 0034655 nucleobase-containing compound catabolic process P 0 0 0 0 0 17 35 35 48.57143 100 -0.262 0.858 1 0044270 cellular nitrogen compound catabolic process P 0 0 0 0 0 17 35 35 48.57143 100 -0.262 0.858 1 0019439 aromatic compound catabolic process P 0 0 0 0 0 17 35 35 48.57143 100 -0.262 0.858 1 0046914 transition metal ion binding F 0 1 1 0 100 14 29 29 48.27586 100 -0.27 0.858 1 0005886 plasma membrane C 15 32 32 46.875 100 16 33 33 48.48485 100 -0.264 0.859 1 0009143 nucleoside triphosphate catabolic process P 1 1 1 100 100 14 29 29 48.27586 100 -0.27 0.859 1 1901292 nucleoside phosphate catabolic process P 0 0 0 0 0 14 29 29 48.27586 100 -0.27 0.859 1 0051641 cellular localization P 0 0 0 0 0 11 23 23 47.82609 100 -0.283 0.861 1 0009056 catabolic process P 0 0 0 0 0 28 57 57 49.12281 100 -0.253 0.864 1 0050993 dimethylallyl diphosphate metabolic process P 0 0 0 0 0 1 1 1 100 100 0.986 1 1 0042286 glutamate-1-semialdehyde 2,1-aminomutase activity F 1 1 1 100 100 1 1 1 100 100 0.986 1 1 0015197 peptide transporter activity F 1 1 1 100 100 1 1 1 100 100 0.986 1 1 0004751 ribose-5-phosphate isomerase activity F 1 1 1 100 100 1 1 1 100 100 0.986 1 1 0009052 pentose-phosphate shunt, non-oxidative branch P 1 1 1 100 100 1 1 1 100 100 0.986 1 1 0004332 fructose-bisphosphate aldolase activity F 1 1 1 100 100 1 1 1 100 100 0.986 1 1 0036361 racemase activity, acting on amino acids and derivatives F 0 0 0 0 0 1 1 1 100 100 0.986 1 1 0015801 aromatic amino acid transport P 1 1 1 100 100 1 1 1 100 100 0.986 1 1 0008966 phosphoglucosamine mutase activity F 1 1 1 100 100 1 1 1 100 100 0.986 1 1 0005315 inorganic phosphate transmembrane transporter activity F 1 1 1 100 100 1 1 1 100 100 0.986 1 1 0051205 protein insertion into membrane P 1 1 1 100 100 1 1 1 100 100 0.986 1 1 0046821 extrachromosomal DNA C 0 0 0 0 0 1 1 1 100 100 0.986 1 1 0005887 integral to plasma membrane C 1 1 1 100 100 1 1 1 100 100 0.986 1 1 0016979 lipoate-protein ligase activity F 0 0 0 0 0 1 1 1 100 100 0.986 1 1 0004316 3-oxoacyl-[acyl-carrier-protein] reductase (NADPH) activity F 1 1 1 100 100 1 1 1 100 100 0.986 1 1 0071451 cellular response to superoxide P 0 0 0 0 0 1 1 1 100 100 0.986 1 1 0006817 phosphate ion transport P 1 1 1 100 100 1 1 1 100 100 0.986 1 1 0016855 racemase and epimerase activity, acting on amino acids and derivatives F 0 0 0 0 0 1 1 1 100 100 0.986 1 1 0004360 glutamine-fructose-6-phosphate transaminase (isomerizing) activity F 1 1 1 100 100 1 1 1 100 100 0.986 1 1 0030261 chromosome condensation P 1 1 1 100 100 1 1 1 100 100 0.986 1 1 0019321 pentose metabolic process P 0 0 0 0 0 1 1 1 100 100 0.986 1 1 0004613 phosphoenolpyruvate carboxykinase (GTP) activity F 1 1 1 100 100 1 1 1 100 100 0.986 1 1 0009041 uridylate kinase activity F 1 1 1 100 100 1 1 1 100 100 0.986 1 1 0016849 phosphorus-oxygen lyase activity F 0 0 0 0 0 1 1 1 100 100 0.986 1 1 0004611 phosphoenolpyruvate carboxykinase activity F 1 1 1 100 100 1 1 1 100 100 0.986 1 1 0000036 ACP phosphopantetheine attachment site binding involved in fatty acid biosynthetic process F 1 1 1 100 100 1 1 1 100 100 0.986 1 1 0004314 [acyl-carrier-protein] S-malonyltransferase activity F 1 1 1 100 100 1 1 1 100 100 0.986 1 1 0015173 aromatic amino acid transmembrane transporter activity F 1 1 1 100 100 1 1 1 100 100 0.986 1 1 0010035 response to inorganic substance P 0 0 0 0 0 1 1 1 100 100 0.986 1 1 0004784 superoxide dismutase activity F 1 1 1 100 100 1 1 1 100 100 0.986 1 1 0004615 phosphomannomutase activity F 1 1 1 100 100 1 1 1 100 100 0.986 1 1 0006431 methionyl-tRNA aminoacylation P 1 1 1 100 100 1 1 1 100 100 0.986 1 1 0003917 DNA topoisomerase type I activity F 1 1 1 100 100 1 1 1 100 100 0.986 1 1 0016298 lipase activity F 0 0 0 0 0 1 1 1 100 100 0.986 1 1 0004825 methionine-tRNA ligase activity F 1 1 1 100 100 1 1 1 100 100 0.986 1 1 0004620 phospholipase activity F 0 0 0 0 0 1 1 1 100 100 0.986 1 1 0070838 divalent metal ion transport P 0 0 0 0 0 1 1 1 100 100 0.986 1 1 0008081 phosphoric diester hydrolase activity F 0 0 0 0 0 1 1 1 100 100 0.986 1 1 0004170 dUTP diphosphatase activity F 1 1 1 100 100 1 1 1 100 100 0.986 1 1 0052906 tRNA (guanine(37)-N(1))-methyltransferase activity F 1 1 1 100 100 1 1 1 100 100 0.986 1 1 0042221 response to chemical stimulus P 0 0 0 0 0 1 1 1 100 100 0.986 1 1 0034614 cellular response to reactive oxygen species P 0 0 0 0 0 1 1 1 100 100 0.986 1 1 0009019 tRNA (guanine-N1-)-methyltransferase activity F 1 1 1 100 100 1 1 1 100 100 0.986 1 1 0003909 DNA ligase activity F 0 0 0 0 0 1 1 1 100 100 0.986 1 1 0048500 signal recognition particle C 1 1 1 100 100 1 1 1 100 100 0.986 1 1 0050797 thymidylate synthase (FAD) activity F 1 1 1 100 100 1 1 1 100 100 0.986 1 1 0072509 divalent inorganic cation transmembrane transporter activity F 0 0 0 0 0 1 1 1 100 100 0.986 1 1 0046527 glucosyltransferase activity F 0 0 0 0 0 1 1 1 100 100 0.986 1 1 0008745 N-acetylmuramoyl-L-alanine amidase activity F 1 1 1 100 100 1 1 1 100 100 0.986 1 1 0009253 peptidoglycan catabolic process P 1 1 1 100 100 1 1 1 100 100 0.986 1 1 0006048 UDP-N-acetylglucosamine biosynthetic process P 1 1 1 100 100 1 1 1 100 100 0.986 1 1 0033862 UMP kinase activity F 1 1 1 100 100 1 1 1 100 100 0.986 1 1 0016886 ligase activity, forming phosphoric ester bonds F 0 0 0 0 0 1 1 1 100 100 0.986 1 1 0008676 3-deoxy-8-phosphooctulonate synthase activity F 1 1 1 100 100 1 1 1 100 100 0.986 1 1 0032269 negative regulation of cellular protein metabolic process P 0 0 0 0 0 1 1 1 100 100 0.986 1 1 0004134 4-alpha-glucanotransferase activity F 1 1 1 100 100 1 1 1 100 100 0.986 1 1 0016721 oxidoreductase activity, acting on superoxide radicals as acceptor F 0 0 0 0 0 1 1 1 100 100 0.986 1 1 0002943 tRNA dihydrouridine synthesis P 1 1 1 100 100 1 1 1 100 100 0.986 1 1 0004596 peptide alpha-N-acetyltransferase activity F 0 0 0 0 0 1 1 1 100 100 0.986 1 1 0000303 response to superoxide P 0 0 0 0 0 1 1 1 100 100 0.986 1 1 0034212 peptide N-acetyltransferase activity F 0 0 0 0 0 1 1 1 100 100 0.986 1 1 0004630 phospholipase D activity F 1 1 1 100 100 1 1 1 100 100 0.986 1 1 0070290 NAPE-specific phospholipase D activity F 1 1 1 100 100 1 1 1 100 100 0.986 1 1 0017150 tRNA dihydrouridine synthase activity F 1 1 1 100 100 1 1 1 100 100 0.986 1 1 0008982 protein-N(PI)-phosphohistidine-sugar phosphotransferase activity F 1 1 1 100 100 1 1 1 100 100 0.986 1 1 0072511 divalent inorganic cation transport P 0 0 0 0 0 1 1 1 100 100 0.986 1 1 0003882 CDP-diacylglycerol-serine O-phosphatidyltransferase activity F 1 1 1 100 100 1 1 1 100 100 0.986 1 1 0004075 biotin carboxylase activity F 1 1 1 100 100 1 1 1 100 100 0.986 1 1 0009266 response to temperature stimulus P 0 0 0 0 0 1 1 1 100 100 0.986 1 1 0008716 D-alanine-D-alanine ligase activity F 1 1 1 100 100 1 1 1 100 100 0.986 1 1 0004318 enoyl-[acyl-carrier-protein] reductase (NADH) activity F 1 1 1 100 100 1 1 1 100 100 0.986 1 1 0016639 oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor F 1 1 1 100 100 1 1 1 100 100 0.986 1 1 0050049 leucine dehydrogenase activity F 1 1 1 100 100 1 1 1 100 100 0.986 1 1 0008441 3’(2’),5’-bisphosphate nucleotidase activity F 1 1 1 100 100 1 1 1 100 100 0.986 1 1 0051184 cofactor transporter activity F 0 0 0 0 0 1 1 1 100 100 0.986 1 1 0046854 phosphatidylinositol phosphorylation P 1 1 1 100 100 1 1 1 100 100 0.986 1 1 0008897 holo-[acyl-carrier-protein] synthase activity F 1 1 1 100 100 1 1 1 100 100 0.986 1 1 0008764 UDP-N-acetylmuramoylalanine-D-glutamate ligase activity F 1 1 1 100 100 1 1 1 100 100 0.986 1 1 0008710 8-amino-7-oxononanoate synthase activity F 1 1 1 100 100 1 1 1 100 100 0.986 1 1 0047480 UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity F 1 1 1 100 100 1 1 1 100 100 0.986 1 1 0008766 UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity F 1 1 1 100 100 1 1 1 100 100 0.986 1 1 0006743 ubiquinone metabolic process P 0 0 0 0 0 1 1 1 100 100 0.986 1 1 0009628 response to abiotic stimulus P 0 0 0 0 0 1 1 1 100 100 0.986 1 1 0009011 starch synthase activity F 1 1 1 100 100 1 1 1 100 100 0.986 1 1 0060590 ATPase regulator activity F 0 0 0 0 0 1 1 1 100 100 0.986 1 1 0017148 negative regulation of translation P 1 1 1 100 100 1 1 1 100 100 0.986 1 1 0090071 negative regulation of ribosome biogenesis P 1 1 1 100 100 1 1 1 100 100 0.986 1 1 0006744 ubiquinone biosynthetic process P 1 1 1 100 100 1 1 1 100 100 0.986 1 1 0033817 beta-ketoacyl-acyl-carrier-protein synthase II activity F 1 1 1 100 100 1 1 1 100 100 0.986 1 1 0016840 carbon-nitrogen lyase activity F 0 0 0 0 0 1 1 1 100 100 0.986 1 1 0042256 mature ribosome assembly P 1 1 1 100 100 1 1 1 100 100 0.986 1 1 0051276 chromosome organization P 0 0 0 0 0 1 1 1 100 100 0.986 1 1 0006323 DNA packaging P 0 0 0 0 0 1 1 1 100 100 0.986 1 1 0051180 vitamin transport P 0 0 0 0 0 1 1 1 100 100 0.986 1 1 0031420 alkali metal ion binding F 0 0 0 0 0 1 1 1 100 100 0.986 1 1 0051181 cofactor transport P 0 0 0 0 0 1 1 1 100 100 0.986 1 1 0015718 monocarboxylic acid transport P 0 0 0 0 0 1 1 1 100 100 0.986 1 1 0016684 oxidoreductase activity, acting on peroxide as acceptor F 0 0 0 0 0 1 1 1 100 100 0.986 1 1 0004791 thioredoxin-disulfide reductase activity F 1 1 1 100 100 1 1 1 100 100 0.986 1 1 0019430 removal of superoxide radicals P 1 1 1 100 100 1 1 1 100 100 0.986 1 1 0008763 UDP-N-acetylmuramate-L-alanine ligase activity F 1 1 1 100 100 1 1 1 100 100 0.986 1 1 0051183 vitamin transporter activity F 0 0 0 0 0 1 1 1 100 100 0.986 1 1 0004427 inorganic diphosphatase activity F 1 1 1 100 100 1 1 1 100 100 0.986 1 1 0004614 phosphoglucomutase activity F 1 1 1 100 100 1 1 1 100 100 0.986 1 1 0008714 AMP nucleosidase activity F 1 1 1 100 100 1 1 1 100 100 0.986 1 1 0070283 radical SAM enzyme activity F 0 0 0 0 0 1 1 1 100 100 0.986 1 1 0006047 UDP-N-acetylglucosamine metabolic process P 0 0 0 0 0 1 1 1 100 100 0.986 1 1 0016869 intramolecular transferase activity, transferring amino groups F 0 0 0 0 0 1 1 1 100 100 0.986 1 1 0015095 magnesium ion transmembrane transporter activity F 1 1 1 100 100 1 1 1 100 100 0.986 1 1 0015693 magnesium ion transport P 1 1 1 100 100 1 1 1 100 100 0.986 1 1 0004831 tyrosine-tRNA ligase activity F 1 1 1 100 100 1 1 1 100 100 0.986 1 1 0070548 L-glutamine aminotransferase activity F 0 0 0 0 0 1 1 1 100 100 0.986 1 1 0006437 tyrosyl-tRNA aminoacylation P 1 1 1 100 100 1 1 1 100 100 0.986 1 1 0008134 transcription factor binding F 1 1 1 100 100 1 1 1 100 100 0.986 1 1 0006231 dTMP biosynthetic process P 1 1 1 100 100 1 1 1 100 100 0.986 1 1 0008097 5S rRNA binding F 1 1 1 100 100 1 1 1 100 100 0.986 1 1 0004045 aminoacyl-tRNA hydrolase activity F 1 1 1 100 100 1 1 1 100 100 0.986 1 1 0005527 macrolide binding F 0 0 0 0 0 1 1 1 100 100 0.986 1 1 0047661 amino-acid racemase activity F 0 0 0 0 0 1 1 1 100 100 0.986 1 1 0004823 leucine-tRNA ligase activity F 1 1 1 100 100 1 1 1 100 100 0.986 1 1 0003933 GTP cyclohydrolase activity F 0 0 0 0 0 1 1 1 100 100 0.986 1 1 0003935 GTP cyclohydrolase II activity F 1 1 1 100 100 1 1 1 100 100 0.986 1 1 0004802 transketolase activity F 1 1 1 100 100 1 1 1 100 100 0.986 1 1 0060589 nucleoside-triphosphatase regulator activity F 0 0 0 0 0 1 1 1 100 100 0.986 1 1 0003911 DNA ligase (NAD+) activity F 1 1 1 100 100 1 1 1 100 100 0.986 1 1 0030234 enzyme regulator activity F 0 0 0 0 0 1 1 1 100 100 0.986 1 1 0004497 monooxygenase activity F 1 1 1 100 100 1 1 1 100 100 0.986 1 1 0042802 identical protein binding F 0 0 0 0 0 1 1 1 100 100 0.986 1 1 0031555 transcriptional attenuation P 0 0 0 0 0 1 1 1 100 100 0.986 1 1 0008686 3,4-dihydroxy-2-butanone-4-phosphate synthase activity F 1 1 1 100 100 1 1 1 100 100 0.986 1 1 0006429 leucyl-tRNA aminoacylation P 1 1 1 100 100 1 1 1 100 100 0.986 1 1 0006430 lysyl-tRNA aminoacylation P 1 1 1 100 100 1 1 1 100 100 0.986 1 1 0003883 CTP synthase activity F 1 1 1 100 100 1 1 1 100 100 0.986 1 1 0004817 cysteine-tRNA ligase activity F 1 1 1 100 100 1 1 1 100 100 0.986 1 1 0006423 cysteinyl-tRNA aminoacylation P 1 1 1 100 100 1 1 1 100 100 0.986 1 1 0004345 glucose-6-phosphate dehydrogenase activity F 1 1 1 100 100 1 1 1 100 100 0.986 1 1 0017057 6-phosphogluconolactonase activity F 1 1 1 100 100 1 1 1 100 100 0.986 1 1 0009106 lipoate metabolic process P 0 0 0 0 0 1 1 1 100 100 0.986 1 1 0004824 lysine-tRNA ligase activity F 1 1 1 100 100 1 1 1 100 100 0.986 1 1 0004106 chorismate mutase activity F 1 1 1 100 100 1 1 1 100 100 0.986 1 1 0051087 chaperone binding F 1 1 1 100 100 1 1 1 100 100 0.986 1 1 0004815 aspartate-tRNA ligase activity F 1 1 1 100 100 1 1 1 100 100 0.986 1 1 0005528 FK506 binding F 1 1 1 100 100 1 1 1 100 100 0.986 1 1 0030488 tRNA methylation P 1 1 1 100 100 1 1 1 100 100 0.986 1 1 0006108 malate metabolic process P 1 1 1 100 100 1 1 1 100 100 0.986 1 1 0016615 malate dehydrogenase activity F 1 1 1 100 100 1 1 1 100 100 0.986 1 1 0030060 L-malate dehydrogenase activity F 1 1 1 100 100 1 1 1 100 100 0.986 1 1 0004821 histidine-tRNA ligase activity F 1 1 1 100 100 1 1 1 100 100 0.986 1 1 0003849 3-deoxy-7-phosphoheptulonate synthase activity F 1 1 1 100 100 1 1 1 100 100 0.986 1 1 0006427 histidyl-tRNA aminoacylation P 1 1 1 100 100 1 1 1 100 100 0.986 1 1 0044620 ACP phosphopantetheine attachment site binding F 0 0 0 0 0 1 1 1 100 100 0.986 1 1 0010285 L,L-diaminopimelate aminotransferase activity F 1 1 1 100 100 1 1 1 100 100 0.986 1 1 0033362 lysine biosynthetic process via diaminopimelate, diaminopimelate-aminotransferase pathway P 1 1 1 100 100 1 1 1 100 100 0.986 1 1 0006433 prolyl-tRNA aminoacylation P 1 1 1 100 100 1 1 1 100 100 0.986 1 1 0004827 proline-tRNA ligase activity F 1 1 1 100 100 1 1 1 100 100 0.986 1 1 0000774 adenyl-nucleotide exchange factor activity F 1 1 1 100 100 1 1 1 100 100 0.986 1 1 0015878 biotin transport P 1 1 1 100 100 1 1 1 100 100 0.986 1 1 0022618 ribonucleoprotein complex assembly P 0 0 0 0 0 1 1 1 100 100 0.986 1 1 0016992 lipoate synthase activity F 1 1 1 100 100 1 1 1 100 100 0.986 1 1 0008840 4-hydroxy-tetrahydrodipicolinate synthase F 1 1 1 100 100 1 1 1 100 100 0.986 1 1 0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen F 0 0 0 0 0 1 1 1 100 100 0.986 1 1 0019988 charged-tRNA amino acid modification P 0 0 0 0 0 1 1 1 100 100 0.986 1 1 0016843 amine-lyase activity F 1 1 1 100 100 1 1 1 100 100 0.986 1 1 0019213 deacetylase activity F 0 0 0 0 0 1 1 1 100 100 0.986 1 1 0004072 aspartate kinase activity F 1 1 1 100 100 1 1 1 100 100 0.986 1 1 0042255 ribosome assembly P 0 0 0 0 0 1 1 1 100 100 0.986 1 1 0006422 aspartyl-tRNA aminoacylation P 1 1 1 100 100 1 1 1 100 100 0.986 1 1 0018904 ether metabolic process P 0 0 0 0 0 1 1 1 100 100 0.986 1 1 0006662 glycerol ether metabolic process P 1 1 1 100 100 1 1 1 100 100 0.986 1 1 0008839 4-hydroxy-tetrahydrodipicolinate reductase F 1 1 1 100 100 1 1 1 100 100 0.986 1 1 0009107 lipoate biosynthetic process P 1 1 1 100 100 1 1 1 100 100 0.986 1 1 0004765 shikimate kinase activity F 1 1 1 100 100 1 1 1 100 100 0.986 1 1 0004148 dihydrolipoyl dehydrogenase activity F 1 1 1 100 100 1 1 1 100 100 0.986 1 1 0008079 translation termination factor activity F 0 0 0 0 0 1 1 2 100 50 0.986 1 1 1901701 cellular response to oxygen-containing compound P 0 0 0 0 0 1 1 1 100 100 0.986 1 1 0006027 glycosaminoglycan catabolic process P 0 0 0 0 0 1 1 1 100 100 0.986 1 1 0070925 organelle assembly P 0 0 0 0 0 1 1 1 100 100 0.986 1 1 0016638 oxidoreductase activity, acting on the CH-NH2 group of donors F 0 0 0 0 0 1 1 1 100 100 0.986 1 1 0042803 protein homodimerization activity F 1 1 1 100 100 1 1 1 100 100 0.986 1 1 0016778 diphosphotransferase activity F 0 0 0 0 0 1 1 1 100 100 0.986 1 1 0004818 glutamate-tRNA ligase activity F 1 1 1 100 100 1 1 1 100 100 0.986 1 1 0006424 glutamyl-tRNA aminoacylation P 1 1 1 100 100 1 1 1 100 100 0.986 1 1 0016420 malonyltransferase activity F 0 0 0 0 0 1 1 1 100 100 0.986 1 1 0006228 UTP biosynthetic process P 1 1 1 100 100 1 1 1 100 100 0.986 1 1 0006183 GTP biosynthetic process P 1 1 1 100 100 1 1 1 100 100 0.986 1 1 0004365 glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity F 1 1 1 100 100 1 1 1 100 100 0.986 1 1 0004550 nucleoside diphosphate kinase activity F 1 1 1 100 100 1 1 1 100 100 0.986 1 1 0044087 regulation of cellular component biogenesis P 0 0 0 0 0 1 1 1 100 100 0.986 1 1 0008878 glucose-1-phosphate adenylyltransferase activity F 1 1 1 100 100 1 1 1 100 100 0.986 1 1 0046834 lipid phosphorylation P 0 0 0 0 0 1 1 1 100 100 0.986 1 1 0008080 N-acetyltransferase activity F 1 1 1 100 100 1 1 1 100 100 0.986 1 1 0008999 ribosomal-protein-alanine N-acetyltransferase activity F 1 1 1 100 100 1 1 1 100 100 0.986 1 1 0050518 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity F 1 1 1 100 100 1 1 1 100 100 0.986 1 1 0042083 5,10-methylenetetrahydrofolate-dependent methyltransferase activity F 0 0 0 0 0 1 1 1 100 100 0.986 1 1 0046488 phosphatidylinositol metabolic process P 0 0 0 0 0 1 1 1 100 100 0.986 1 1 0006165 nucleoside diphosphate phosphorylation P 1 1 1 100 100 1 1 1 100 100 0.986 1 1 0051668 localization within membrane P 0 0 0 0 0 1 1 1 100 100 0.986 1 1 0051192 prosthetic group binding F 0 0 0 0 0 1 1 1 100 100 0.986 1 1 0071826 ribonucleoprotein complex subunit organization P 0 0 0 0 0 1 1 1 100 100 0.986 1 1 0016419 S-malonyltransferase activity F 0 0 0 0 0 1 1 1 100 100 0.986 1 1 0008759 UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity F 1 1 1 100 100 1 1 1 100 100 0.986 1 1 0047451 3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity F 1 1 1 100 100 1 1 1 100 100 0.986 1 1 0019171 3-hydroxyacyl-[acyl-carrier-protein] dehydratase activity F 1 1 1 100 100 1 1 1 100 100 0.986 1 1 0008780 acyl-[acyl-carrier-protein]-UDP-N-acetylglucosamine O-acyltransferase activity F 1 1 1 100 100 1 1 1 100 100 0.986 1 1 0005727 extrachromosomal circular DNA C 1 1 1 100 100 1 1 1 100 100 0.986 1 1 0090069 regulation of ribosome biogenesis P 0 0 0 0 0 1 1 1 100 100 0.986 1 1 0006026 aminoglycan catabolic process P 0 0 0 0 0 1 1 1 100 100 0.986 1 1 0008837 diaminopimelate epimerase activity F 1 1 1 100 100 1 1 1 100 100 0.986 1 1 0004372 glycine hydroxymethyltransferase activity F 1 1 1 100 100 1 1 1 100 100 0.986 1 1 0006563 L-serine metabolic process P 1 1 1 100 100 1 1 1 100 100 0.986 1 1 0019264 glycine biosynthetic process from serine P 1 1 1 100 100 1 1 1 100 100 0.986 1 1 0004479 methionyl-tRNA formyltransferase activity F 1 1 1 100 100 1 1 1 100 100 0.986 1 1 0008685 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity F 1 1 1 100 100 1 1 1 100 100 0.986 1 1 0003729 mRNA binding F 1 1 1 100 100 1 1 1 100 100 0.986 1 1 0071951 conversion of methionyl-tRNA to N-formyl-methionyl-tRNA P 1 1 1 100 100 1 1 1 100 100 0.986 1 1 0051920 peroxiredoxin activity F 1 1 1 100 100 1 1 1 100 100 0.986 1 1 0008312 7S RNA binding F 1 1 1 100 100 1 1 1 100 100 0.986 1 1 0031072 heat shock protein binding F 1 1 1 100 100 1 1 1 100 100 0.986 1 1 0009408 response to heat P 1 1 1 100 100 1 1 1 100 100 0.986 1 1 0000175 3’-5’-exoribonuclease activity F 1 1 1 100 100 1 1 1 100 100 0.986 1 1 0003863 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity F 1 1 1 100 100 1 1 1 100 100 0.986 1 1 1901700 response to oxygen-containing compound P 0 0 0 0 0 1 1 1 100 100 0.986 1 1 0034599 cellular response to oxidative stress P 0 0 0 0 0 1 1 1 100 100 0.986 1 1 0043590 bacterial nucleoid C 1 1 1 100 100 1 1 1 100 100 0.986 1 1 0004150 dihydroneopterin aldolase activity F 1 1 1 100 100 1 1 1 100 100 0.986 1 1 0004337 geranyltranstransferase activity F 1 1 1 100 100 1 1 1 100 100 0.986 1 1 0004601 peroxidase activity F 1 1 1 100 100 1 1 1 100 100 0.986 1 1 0030955 potassium ion binding F 1 1 1 100 100 1 1 1 100 100 0.986 1 1 0051745 4-hydroxy-3-methylbut-2-en-1-yl diphosphate reductase activity F 1 1 1 100 100 1 1 1 100 100 0.986 1 1 0004311 farnesyltranstransferase activity F 1 1 1 100 100 1 1 1 100 100 0.986 1 1 0004801 sedoheptulose-7-phosphate:D-glyceraldehyde-3-phosphate glyceronetransferase activity F 1 1 1 100 100 1 1 1 100 100 0.986 1 1 0016149 translation release factor activity, codon specific F 1 1 2 100 50 1 1 2 100 50 0.986 1 1 0051538 3 iron, 4 sulfur cluster binding F 1 1 1 100 100 1 1 1 100 100 0.986 1 1 0004161 dimethylallyltranstransferase activity F 1 1 1 100 100 1 1 1 100 100 0.986 1 1 0050992 dimethylallyl diphosphate biosynthetic process P 1 1 1 100 100 1 1 1 100 100 0.986 1 1 0046073 dTMP metabolic process P 0 0 0 0 0 1 1 1 100 100 0.986 1 1 0006402 mRNA catabolic process P 1 1 1 100 100 1 1 1 100 100 0.986 1 1 0004146 dihydrofolate reductase activity F 1 1 1 100 100 1 1 1 100 100 0.986 1 1 0070887 cellular response to chemical stimulus P 0 0 0 0 0 1 1 1 100 100 0.986 1 1 0003848 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase activity F 1 1 1 100 100 1 1 1 100 100 0.986 1 1 0004156 dihydropteroate synthase activity F 1 1 1 100 100 1 1 1 100 100 0.986 1 1 0004654 polyribonucleotide nucleotidyltransferase activity F 1 1 1 100 100 1 1 1 100 100 0.986 1 1 0031564 transcription antitermination P 1 1 1 100 100 1 1 1 100 100 0.986 1 1 0004743 pyruvate kinase activity F 1 1 1 100 100 1 1 1 100 100 0.986 1 1 0003844 1,4-alpha-glucan branching enzyme activity F 1 1 1 100 100 1 1 1 100 100 0.986 1 1 1901070 guanosine-containing compound biosynthetic process P 0 0 0 0 0 1 1 1 100 100 0.986 1 1 0000015 phosphopyruvate hydratase complex C 1 1 1 100 100 1 1 1 100 100 0.986 1 1 0042586 peptide deformylase activity F 1 1 1 100 100 1 1 1 100 100 0.986 1 1 0004634 phosphopyruvate hydratase activity F 1 1 1 100 100 1 1 1 100 100 0.986 1 1 0046051 UTP metabolic process P 0 0 0 0 0 1 1 1 100 100 0.986 1 1 0006428 isoleucyl-tRNA aminoacylation P 1 1 1 100 100 1 1 1 100 100 0.986 1 1 0006436 tryptophanyl-tRNA aminoacylation P 1 1 1 100 100 1 1 1 100 100 0.986 1 1 0006979 response to oxidative stress P 0 0 0 0 0 1 1 1 100 100 0.986 1 1 0003747 translation release factor activity F 1 1 2 100 50 1 1 2 100 50 0.986 1 1 0004830 tryptophan-tRNA ligase activity F 1 1 1 100 100 1 1 1 100 100 0.986 1 1 0004822 isoleucine-tRNA ligase activity F 1 1 1 100 100 1 1 1 100 100 0.986 1 1 0015225 biotin transporter activity F 1 1 1 100 100 1 1 1 100 100 0.986 1 1 0000302 response to reactive oxygen species P 0 0 0 0 0 1 1 1 100 100 0.986 1 1 0051248 negative regulation of protein metabolic process P 0 0 0 0 0 1 1 1 100 100 0.986 1 1 1901661 quinone metabolic process P 0 0 0 0 0 2 3 3 66.66666 100 0.553 1 1 0042180 cellular ketone metabolic process P 0 0 0 0 0 2 3 3 66.66666 100 0.553 1 1 0010181 FMN binding F 2 3 3 66.66666 100 2 3 3 66.66666 100 0.553 1 1 0009233 menaquinone metabolic process P 0 0 0 0 0 2 3 3 66.66666 100 0.553 1 1 0016783 sulfurtransferase activity F 2 2 2 100 100 2 3 3 66.66666 100 0.553 1 1 0009162 deoxyribonucleoside monophosphate metabolic process P 0 0 0 0 0 2 3 3 66.66666 100 0.553 1 1 0031163 metallo-sulfur cluster assembly P 0 0 0 0 0 2 3 3 66.66666 100 0.553 1 1 0009176 pyrimidine deoxyribonucleoside monophosphate metabolic process P 0 0 0 0 0 2 3 3 66.66666 100 0.553 1 1 0009070 serine family amino acid biosynthetic process P 0 0 0 0 0 2 3 3 66.66666 100 0.553 1 1 0010605 negative regulation of macromolecule metabolic process P 0 0 0 0 0 2 3 3 66.66666 100 0.553 1 1 0006544 glycine metabolic process P 1 1 1 100 100 2 3 3 66.66666 100 0.553 1 1 0031324 negative regulation of cellular metabolic process P 0 0 0 0 0 2 3 3 66.66666 100 0.553 1 1 0015833 peptide transport P 2 3 3 66.66666 100 2 3 3 66.66666 100 0.553 1 1 0009317 acetyl-CoA carboxylase complex C 2 3 3 66.66666 100 2 3 3 66.66666 100 0.553 1 1 0003989 acetyl-CoA carboxylase activity F 2 3 3 66.66666 100 2 3 3 66.66666 100 0.553 1 1 1901663 quinone biosynthetic process P 0 0 0 0 0 2 3 3 66.66666 100 0.553 1 1 0008565 protein transporter activity F 1 2 2 50 100 2 3 3 66.66666 100 0.553 1 1 0016782 transferase activity, transferring sulfur-containing groups F 0 0 0 0 0 2 3 3 66.66666 100 0.553 1 1 2000113 negative regulation of cellular macromolecule biosynthetic process P 0 0 0 0 0 2 3 3 66.66666 100 0.553 1 1 0016868 intramolecular transferase activity, phosphotransferases F 2 3 3 66.66666 100 2 3 3 66.66666 100 0.553 1 1 0009129 pyrimidine nucleoside monophosphate metabolic process P 0 0 0 0 0 2 3 3 66.66666 100 0.553 1 1 0042181 ketone biosynthetic process P 0 0 0 0 0 2 3 3 66.66666 100 0.553 1 1 0009157 deoxyribonucleoside monophosphate biosynthetic process P 0 0 0 0 0 2 3 3 66.66666 100 0.553 1 1 0016885 ligase activity, forming carbon-carbon bonds F 0 0 0 0 0 2 3 3 66.66666 100 0.553 1 1 0009890 negative regulation of biosynthetic process P 0 0 0 0 0 2 3 3 66.66666 100 0.553 1 1 0015288 porin activity F 2 3 3 66.66666 100 2 3 3 66.66666 100 0.553 1 1 0016421 CoA carboxylase activity F 0 0 0 0 0 2 3 3 66.66666 100 0.553 1 1 0010558 negative regulation of macromolecule biosynthetic process P 0 0 0 0 0 2 3 3 66.66666 100 0.553 1 1 0031327 negative regulation of cellular biosynthetic process P 0 0 0 0 0 2 3 3 66.66666 100 0.553 1 1 0009064 glutamine family amino acid metabolic process P 0 0 0 0 0 2 3 3 66.66666 100 0.553 1 1 0016226 iron-sulfur cluster assembly P 2 3 3 66.66666 100 2 3 3 66.66666 100 0.553 1 1 0022829 wide pore channel activity F 0 0 0 0 0 2 3 3 66.66666 100 0.553 1 1 0015267 channel activity F 0 0 0 0 0 2 3 3 66.66666 100 0.553 1 1 0042592 homeostatic process P 0 0 0 0 0 2 3 3 66.66666 100 0.553 1 1 0019725 cellular homeostasis P 0 0 0 0 0 2 3 3 66.66666 100 0.553 1 1 0003743 translation initiation factor activity F 2 3 3 66.66666 100 2 3 3 66.66666 100 0.553 1 1 0016668 oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor F 1 1 1 100 100 2 3 3 66.66666 100 0.553 1 1 0009234 menaquinone biosynthetic process P 2 3 3 66.66666 100 2 3 3 66.66666 100 0.553 1 1 0030246 carbohydrate binding F 2 3 3 66.66666 100 2 3 3 66.66666 100 0.553 1 1 0045454 cell redox homeostasis P 2 3 3 66.66666 100 2 3 3 66.66666 100 0.553 1 1 0008175 tRNA methyltransferase activity F 1 1 1 100 100 2 3 3 66.66666 100 0.553 1 1 0016744 transferase activity, transferring aldehyde or ketonic groups F 0 0 0 0 0 2 3 3 66.66666 100 0.553 1 1 0009130 pyrimidine nucleoside monophosphate biosynthetic process P 0 0 0 0 0 2 3 3 66.66666 100 0.553 1 1 0009892 negative regulation of metabolic process P 0 0 0 0 0 2 3 3 66.66666 100 0.553 1 1 0044445 cytosolic part C 0 0 0 0 0 2 3 3 66.66666 100 0.553 1 1 0009177 pyrimidine deoxyribonucleoside monophosphate biosynthetic process P 0 0 0 0 0 2 3 3 66.66666 100 0.553 1 1 0022803 passive transmembrane transporter activity F 0 0 0 0 0 2 3 3 66.66666 100 0.553 1 1 0001522 pseudouridine synthesis P 3 5 6 60 83.33334 3 5 6 60 83.33334 0.416 1 1 0071822 protein complex subunit organization P 0 0 0 0 0 3 5 6 60 83.33334 0.416 1 1 0006448 regulation of translational elongation P 0 0 0 0 0 3 5 5 60 100 0.416 1 1 0051287 NAD binding F 3 5 5 60 100 3 5 5 60 100 0.416 1 1 0009982 pseudouridine synthase activity F 3 5 6 60 83.33334 3 5 6 60 83.33334 0.416 1 1 0006450 regulation of translational fidelity P 3 5 5 60 100 3 5 5 60 100 0.416 1 1 0015370 solute:sodium symporter activity F 0 0 0 0 0 3 5 5 60 100 0.416 1 1 0006760 folic acid-containing compound metabolic process P 1 1 1 100 100 3 5 5 60 100 0.416 1 1 0015081 sodium ion transmembrane transporter activity F 0 0 0 0 0 3 5 5 60 100 0.416 1 1 0009148 pyrimidine nucleoside triphosphate biosynthetic process P 0 0 0 0 0 3 5 5 60 100 0.416 1 1 0008408 3’-5’ exonuclease activity F 2 3 3 66.66666 100 3 5 5 60 100 0.416 1 1 0042558 pteridine-containing compound metabolic process P 1 1 1 100 100 3 5 5 60 100 0.416 1 1 0046983 protein dimerization activity F 2 4 4 50 100 3 5 5 60 100 0.416 1 1 0033692 cellular polysaccharide biosynthetic process P 0 0 0 0 0 4 7 7 57.14286 100 0.341 1 1 0000271 polysaccharide biosynthetic process P 0 0 0 0 0 4 7 7 57.14286 100 0.341 1 1 0044264 cellular polysaccharide metabolic process P 0 0 0 0 0 4 7 7 57.14286 100 0.341 1 1 0006740 NADPH regeneration P 0 0 0 0 0 4 7 7 57.14286 100 0.341 1 1 0072524 pyridine-containing compound metabolic process P 0 0 0 0 0 4 7 7 57.14286 100 0.341 1 1 0019362 pyridine nucleotide metabolic process P 0 0 0 0 0 4 7 7 57.14286 100 0.341 1 1 0006739 NADP metabolic process P 0 0 0 0 0 4 7 7 57.14286 100 0.341 1 1 0006098 pentose-phosphate shunt P 4 7 7 57.14286 100 4 7 7 57.14286 100 0.341 1 1 0005976 polysaccharide metabolic process P 0 0 0 0 0 4 7 7 57.14286 100 0.341 1 1 0007059 chromosome segregation P 4 7 7 57.14286 100 4 7 7 57.14286 100 0.341 1 1 0046496 nicotinamide nucleotide metabolic process P 0 0 0 0 0 4 7 7 57.14286 100 0.341 1 1 0006261 DNA-dependent DNA replication P 3 4 4 75 100 4 7 7 57.14286 100 0.341 1 1 0034637 cellular carbohydrate biosynthetic process P 0 0 0 0 0 4 7 7 57.14286 100 0.341 1 1 0072527 pyrimidine-containing compound metabolic process P 0 0 0 0 0 5 9 9 55.55556 100 0.292 1 1 0006184 GTP catabolic process P 5 9 9 55.55556 100 5 9 9 55.55556 100 0.292 1 1 0044262 cellular carbohydrate metabolic process P 1 1 1 100 100 5 9 9 55.55556 100 0.292 1 1 1901069 guanosine-containing compound catabolic process P 0 0 0 0 0 5 9 9 55.55556 100 0.292 1 1 0003924 GTPase activity F 5 9 9 55.55556 100 5 9 9 55.55556 100 0.292 1 1 0009057 macromolecule catabolic process P 0 0 0 0 0 5 9 9 55.55556 100 0.292 1 1 0071103 DNA conformation change P 0 0 0 0 0 5 9 9 55.55556 100 0.292 1 1 0071554 cell wall organization or biogenesis P 0 0 0 0 0 6 11 11 54.54546 100 0.256 1 1 0016836 hydro-lyase activity F 1 1 1 100 100 6 11 13 54.54546 84.61539 0.256 1 1 0044036 cell wall macromolecule metabolic process P 0 0 0 0 0 6 11 11 54.54546 100 0.256 1 1 0004175 endopeptidase activity F 0 0 0 0 0 6 11 11 54.54546 100 0.256 1 1 0022890 inorganic cation transmembrane transporter activity F 0 0 0 0 0 7 13 13 53.84615 100 0.227 1 1 0006400 tRNA modification P 3 6 6 50 100 7 13 13 53.84615 100 0.227 1 1 0006464 cellular protein modification process P 1 4 4 25 100 8 15 15 53.33333 100 0.205 1 1 0036211 protein modification process P 0 0 0 0 0 8 15 15 53.33333 100 0.205 1 1 0006006 glucose metabolic process P 2 2 2 100 100 9 17 17 52.94118 100 0.185 1 1 0019318 hexose metabolic process P 0 0 0 0 0 9 17 17 52.94118 100 0.185 1 1 0016747 transferase activity, transferring acyl groups other than amino-acyl groups F 2 5 5 40 100 9 17 17 52.94118 100 0.185 1 1 0065008 regulation of biological quality P 0 0 0 0 0 10 19 19 52.63158 100 0.169 1 1 0019867 outer membrane C 6 13 13 46.15385 100 10 19 19 52.63158 100 0.169 1 1 0005996 monosaccharide metabolic process P 0 0 0 0 0 10 19 19 52.63158 100 0.169 1 1 0006811 ion transport P 3 11 11 27.27273 100 16 31 32 51.6129 96.875 0.102 1 1 0044255 cellular lipid metabolic process P 0 0 0 0 0 19 37 37 51.35135 100 0.079 1 1 0006629 lipid metabolic process P 7 14 14 50 100 19 37 37 51.35135 100 0.079 1 1 0071702 organic substance transport P 0 0 0 0 0 22 43 44 51.16279 97.72727 0.06 1 1 0044281 small molecule metabolic process P 0 0 0 0 0 70 138 139 50.72464 99.28058 0.001 1 1 GO Gene Ontology r 0 0 0 0 0 316 623 627 50.72231 99.36204 0 1 1 0004077 biotin-[acetyl-CoA-carboxylase] ligase activity F 1 2 2 50 100 1 2 2 50 100 -0.02 1 1 0046078 dUMP metabolic process P 0 0 0 0 0 1 2 2 50 100 -0.02 1 1 0018271 biotin-protein ligase activity F 0 0 0 0 0 1 2 2 50 100 -0.02 1 1 0051253 negative regulation of RNA metabolic process P 0 0 0 0 0 1 2 2 50 100 -0.02 1 1 0004674 protein serine/threonine kinase activity F 1 2 2 50 100 1 2 2 50 100 -0.02 1 1 0008252 nucleotidase activity F 0 0 0 0 0 1 2 2 50 100 -0.02 1 1 0033177 proton-transporting two-sector ATPase complex, proton-transporting domain C 1 1 1 100 100 1 2 2 50 100 -0.02 1 1 0016423 tRNA (guanine) methyltransferase activity F 0 0 0 0 0 1 2 2 50 100 -0.02 1 1 0004176 ATP-dependent peptidase activity F 1 2 2 50 100 1 2 2 50 100 -0.02 1 1 0006226 dUMP biosynthetic process P 1 2 2 50 100 1 2 2 50 100 -0.02 1 1 0022904 respiratory electron transport chain P 1 2 2 50 100 1 2 2 50 100 -0.02 1 1 0022900 electron transport chain P 0 0 0 0 0 1 2 2 50 100 -0.02 1 1 0034622 cellular macromolecular complex assembly P 0 0 0 0 0 1 2 2 50 100 -0.02 1 1 0070526 threonylcarbamoyladenosine biosynthetic process P 1 2 2 50 100 1 2 2 50 100 -0.02 1 1 2001295 malonyl-CoA biosynthetic process P 1 2 2 50 100 1 2 2 50 100 -0.02 1 1 0019202 amino acid kinase activity F 0 0 0 0 0 1 2 2 50 100 -0.02 1 1 0009249 protein lipoylation P 1 2 2 50 100 1 2 2 50 100 -0.02 1 1 0016411 acylglycerol O-acyltransferase activity F 0 0 0 0 0 1 2 2 50 100 -0.02 1 1 0006275 regulation of DNA replication P 1 2 2 50 100 1 2 2 50 100 -0.02 1 1 0004177 aminopeptidase activity F 1 2 2 50 100 1 2 2 50 100 -0.02 1 1 0006270 DNA replication initiation P 1 2 2 50 100 1 2 2 50 100 -0.02 1 1 0003688 DNA replication origin binding F 1 2 2 50 100 1 2 2 50 100 -0.02 1 1 0046080 dUTP metabolic process P 1 2 2 50 100 1 2 2 50 100 -0.02 1 1 0015698 inorganic anion transport P 0 0 0 0 0 1 2 2 50 100 -0.02 1 1 0000156 phosphorelay response regulator activity F 1 2 2 50 100 1 2 2 50 100 -0.02 1 1 0035556 intracellular signal transduction P 1 2 2 50 100 1 2 2 50 100 -0.02 1 1 0004826 phenylalanine-tRNA ligase activity F 1 2 2 50 100 1 2 2 50 100 -0.02 1 1 0050567 glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity F 1 2 2 50 100 1 2 2 50 100 -0.02 1 1 0006432 phenylalanyl-tRNA aminoacylation P 1 2 2 50 100 1 2 2 50 100 -0.02 1 1 0003841 1-acylglycerol-3-phosphate O-acyltransferase activity F 1 2 2 50 100 1 2 2 50 100 -0.02 1 1 0016407 acetyltransferase activity F 0 0 0 0 0 1 2 2 50 100 -0.02 1 1 0051052 regulation of DNA metabolic process P 0 0 0 0 0 1 2 2 50 100 -0.02 1 1 0045152 antisigma factor binding F 1 2 2 50 100 1 2 2 50 100 -0.02 1 1 0004523 ribonuclease H activity F 1 2 2 50 100 1 2 2 50 100 -0.02 1 1 0018065 protein-cofactor linkage P 0 0 0 0 0 1 2 2 50 100 -0.02 1 1 2001293 malonyl-CoA metabolic process P 0 0 0 0 0 1 2 2 50 100 -0.02 1 1 0004003 ATP-dependent DNA helicase activity F 1 2 2 50 100 1 2 2 50 100 -0.02 1 1 0016854 racemase and epimerase activity F 0 0 0 0 0 1 2 2 50 100 -0.02 1 1 0010629 negative regulation of gene expression P 0 0 0 0 0 1 2 2 50 100 -0.02 1 1 0009088 threonine biosynthetic process P 1 2 2 50 100 1 2 2 50 100 -0.02 1 1 0046400 keto-3-deoxy-D-manno-octulosonic acid metabolic process P 0 0 0 0 0 1 2 2 50 100 -0.02 1 1 0005310 dicarboxylic acid transmembrane transporter activity F 0 0 0 0 0 1 2 2 50 100 -0.02 1 1 0009037 tyrosine-based site-specific recombinase activity F 1 2 2 50 100 1 2 2 50 100 -0.02 1 1 0006313 transposition, DNA-mediated P 1 2 2 50 100 1 2 2 50 100 -0.02 1 1 0030163 protein catabolic process P 1 2 2 50 100 1 2 2 50 100 -0.02 1 1 0017038 protein import P 1 2 2 50 100 1 2 2 50 100 -0.02 1 1 0009318 exodeoxyribonuclease VII complex C 1 2 2 50 100 1 2 2 50 100 -0.02 1 1 0008855 exodeoxyribonuclease VII activity F 1 2 2 50 100 1 2 2 50 100 -0.02 1 1 0030258 lipid modification P 0 0 0 0 0 1 2 2 50 100 -0.02 1 1 0006308 DNA catabolic process P 1 2 2 50 100 1 2 2 50 100 -0.02 1 1 0004109 coproporphyrinogen oxidase activity F 1 2 2 50 100 1 2 2 50 100 -0.02 1 1 0046961 proton-transporting ATPase activity, rotational mechanism F 1 2 2 50 100 1 2 2 50 100 -0.02 1 1 0016410 N-acyltransferase activity F 0 1 1 0 100 1 2 2 50 100 -0.02 1 1 0043244 regulation of protein complex disassembly P 0 0 0 0 0 1 2 2 50 100 -0.02 1 1 0070525 threonylcarbamoyladenosine metabolic process P 0 0 0 0 0 1 2 2 50 100 -0.02 1 1 0008907 integrase activity F 0 0 0 0 0 1 2 2 50 100 -0.02 1 1 0004532 exoribonuclease activity F 0 0 0 0 0 1 2 2 50 100 -0.02 1 1 0003872 6-phosphofructokinase activity F 1 2 2 50 100 1 2 2 50 100 -0.02 1 1 0045892 negative regulation of transcription, DNA-dependent P 1 2 2 50 100 1 2 2 50 100 -0.02 1 1 0051172 negative regulation of nitrogen compound metabolic process P 0 0 0 0 0 1 2 2 50 100 -0.02 1 1 0070402 NADPH binding F 1 2 2 50 100 1 2 2 50 100 -0.02 1 1 0016645 oxidoreductase activity, acting on the CH-NH group of donors F 0 0 0 0 0 1 2 2 50 100 -0.02 1 1 0032196 transposition P 0 0 0 0 0 1 2 2 50 100 -0.02 1 1 0005945 6-phosphofructokinase complex C 1 2 2 50 100 1 2 2 50 100 -0.02 1 1 0065003 macromolecular complex assembly P 0 0 0 0 0 1 2 2 50 100 -0.02 1 1 0009009 site-specific recombinase activity F 0 0 0 0 0 1 2 2 50 100 -0.02 1 1 0046085 adenosine metabolic process P 0 0 0 0 0 1 2 2 50 100 -0.02 1 1 0046653 tetrahydrofolate metabolic process P 0 0 0 0 0 1 2 2 50 100 -0.02 1 1 0004133 glycogen debranching enzyme activity F 0 0 0 0 0 1 2 2 50 100 -0.02 1 1 0046939 nucleotide phosphorylation P 0 1 1 0 100 1 2 2 50 100 -0.02 1 1 0008443 phosphofructokinase activity F 0 0 0 0 0 1 2 2 50 100 -0.02 1 1 0019200 carbohydrate kinase activity F 0 0 0 0 0 1 2 2 50 100 -0.02 1 1 0019294 keto-3-deoxy-D-manno-octulosonic acid biosynthetic process P 1 2 2 50 100 1 2 2 50 100 -0.02 1 1 0004834 tryptophan synthase activity F 1 2 3 50 66.66666 1 2 3 50 66.66666 -0.02 1 1 0016896 exoribonuclease activity, producing 5’-phosphomonoesters F 0 0 0 0 0 1 2 2 50 100 -0.02 1 1 0042026 protein refolding P 1 2 2 50 100 1 2 2 50 100 -0.02 1 1 0019238 cyclohydrolase activity F 0 0 0 0 0 1 2 2 50 100 -0.02 1 1 0006002 fructose 6-phosphate metabolic process P 1 2 2 50 100 1 2 2 50 100 -0.02 1 1 0042575 DNA polymerase complex C 0 0 0 0 0 1 2 2 50 100 -0.02 1 1 0009986 cell surface C 1 2 2 50 100 1 2 2 50 100 -0.02 1 1 0006566 threonine metabolic process P 0 0 0 0 0 1 2 2 50 100 -0.02 1 1 0006835 dicarboxylic acid transport P 1 2 2 50 100 1 2 2 50 100 -0.02 1 1 0035999 tetrahydrofolate interconversion P 1 2 2 50 100 1 2 2 50 100 -0.02 1 1 0017153 sodium:dicarboxylate symporter activity F 1 2 2 50 100 1 2 2 50 100 -0.02 1 1 0006730 one-carbon metabolic process P 1 2 2 50 100 1 2 2 50 100 -0.02 1 1 0036442 hydrogen-exporting ATPase activity F 0 0 0 0 0 1 2 2 50 100 -0.02 1 1 0072348 sulfur compound transport P 0 0 0 0 0 1 2 2 50 100 -0.02 1 1 0031554 regulation of DNA-dependent transcription, termination P 0 1 1 0 100 1 2 2 50 100 -0.02 1 1 0009360 DNA polymerase III complex C 1 2 2 50 100 1 2 2 50 100 -0.02 1 1 0045934 negative regulation of nucleobase-containing compound metabolic process P 0 0 0 0 0 1 2 2 50 100 -0.02 1 1 0016646 oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor F 0 0 0 0 0 1 2 2 50 100 -0.02 1 1 0047334 diphosphate-fructose-6-phosphate 1-phosphotransferase activity F 1 2 2 50 100 1 2 2 50 100 -0.02 1 1 0016774 phosphotransferase activity, carboxyl group as acceptor F 0 0 0 0 0 1 2 2 50 100 -0.02 1 1 0003697 single-stranded DNA binding F 2 4 4 50 100 2 4 4 50 100 -0.029 1 1 0009394 2’-deoxyribonucleotide metabolic process P 0 0 0 0 0 2 4 4 50 100 -0.029 1 1 0030254 protein secretion by the type III secretion system P 2 4 4 50 100 2 4 4 50 100 -0.029 1 1 0042578 phosphoric ester hydrolase activity F 0 0 0 0 0 2 4 4 50 100 -0.029 1 1 0009265 2’-deoxyribonucleotide biosynthetic process P 0 0 0 0 0 2 4 4 50 100 -0.029 1 1 0048519 negative regulation of biological process P 0 0 0 0 0 2 4 4 50 100 -0.029 1 1 0015074 DNA integration P 2 4 4 50 100 2 4 4 50 100 -0.029 1 1 0048523 negative regulation of cellular process P 0 0 0 0 0 2 4 4 50 100 -0.029 1 1 0009219 pyrimidine deoxyribonucleotide metabolic process P 0 0 0 0 0 2 4 4 50 100 -0.029 1 1 0019692 deoxyribose phosphate metabolic process P 0 0 0 0 0 2 4 4 50 100 -0.029 1 1 0046385 deoxyribose phosphate biosynthetic process P 0 0 0 0 0 2 4 4 50 100 -0.029 1 1 0003684 damaged DNA binding F 2 4 4 50 100 2 4 4 50 100 -0.029 1 1 0008374 O-acyltransferase activity F 0 0 0 0 0 2 4 4 50 100 -0.029 1 1 0009221 pyrimidine deoxyribonucleotide biosynthetic process P 0 0 0 0 0 2 4 4 50 100 -0.029 1 1 0006401 RNA catabolic process P 1 2 2 50 100 2 4 4 50 100 -0.029 1 1 0006575 cellular modified amino acid metabolic process P 0 0 0 0 0 3 6 6 50 100 -0.036 1 1 0016758 transferase activity, transferring hexosyl groups F 0 1 1 0 100 3 6 6 50 100 -0.036 1 1 0016860 intramolecular oxidoreductase activity F 0 0 0 0 0 3 6 6 50 100 -0.036 1 1 0003899 DNA-directed RNA polymerase activity F 3 6 6 50 100 3 6 6 50 100 -0.036 1 1 0046490 isopentenyl diphosphate metabolic process P 0 0 0 0 0 3 6 6 50 100 -0.036 1 1 0019682 glyceraldehyde-3-phosphate metabolic process P 0 0 0 0 0 3 6 6 50 100 -0.036 1 1 0009240 isopentenyl diphosphate biosynthetic process P 0 0 0 0 0 3 6 6 50 100 -0.036 1 1 0006081 cellular aldehyde metabolic process P 0 0 0 0 0 3 6 6 50 100 -0.036 1 1 0019288 isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway P 3 6 6 50 100 3 6 6 50 100 -0.036 1 1 0009206 purine ribonucleoside triphosphate biosynthetic process P 0 0 0 0 0 3 6 6 50 100 -0.036 1 1 0009145 purine nucleoside triphosphate biosynthetic process P 0 0 0 0 0 3 6 6 50 100 -0.036 1 1 0034062 RNA polymerase activity F 0 0 0 0 0 3 6 6 50 100 -0.036 1 1 0022607 cellular component assembly P 0 0 0 0 0 3 6 6 50 100 -0.036 1 1 0009311 oligosaccharide metabolic process P 0 0 0 0 0 4 8 8 50 100 -0.041 1 1 0006720 isoprenoid metabolic process P 0 0 0 0 0 4 8 8 50 100 -0.041 1 1 0009312 oligosaccharide biosynthetic process P 0 0 0 0 0 4 8 8 50 100 -0.041 1 1 0008299 isoprenoid biosynthetic process P 4 8 8 50 100 4 8 8 50 100 -0.041 1 1 0000270 peptidoglycan metabolic process P 0 0 0 0 0 5 10 10 50 100 -0.046 1 1 0030313 cell envelope C 0 0 0 0 0 5 10 10 50 100 -0.046 1 1 0030203 glycosaminoglycan metabolic process P 0 0 0 0 0 5 10 10 50 100 -0.046 1 1 0030312 external encapsulating structure C 0 0 0 0 0 5 10 10 50 100 -0.046 1 1 0034220 ion transmembrane transport P 0 0 0 0 0 5 10 11 50 90.90909 -0.046 1 1 0006022 aminoglycan metabolic process P 0 0 0 0 0 5 10 10 50 100 -0.046 1 1 0009142 nucleoside triphosphate biosynthetic process P 0 0 0 0 0 5 10 10 50 100 -0.046 1 1 0031975 envelope C 0 0 0 0 0 5 10 10 50 100 -0.046 1 1 0008514 organic anion transmembrane transporter activity F 0 0 0 0 0 5 10 10 50 100 -0.046 1 1 0043648 dicarboxylic acid metabolic process P 0 0 0 0 0 6 12 12 50 100 -0.05 1 1 0000902 cell morphogenesis P 1 1 1 100 100 6 12 12 50 100 -0.05 1 1 0015077 monovalent inorganic cation transmembrane transporter activity F 0 0 0 0 0 6 12 12 50 100 -0.05 1 1 0048856 anatomical structure development P 0 0 0 0 0 6 12 12 50 100 -0.05 1 1 0009653 anatomical structure morphogenesis P 0 0 0 0 0 6 12 12 50 100 -0.05 1 1 0048869 cellular developmental process P 0 0 0 0 0 6 12 12 50 100 -0.05 1 1 0006310 DNA recombination P 6 12 12 50 100 6 12 12 50 100 -0.05 1 1 0044767 single-organism developmental process P 0 0 0 0 0 6 12 12 50 100 -0.05 1 1 0032989 cellular component morphogenesis P 0 0 0 0 0 6 12 12 50 100 -0.05 1 1 0032502 developmental process P 0 0 0 0 0 6 12 12 50 100 -0.05 1 1 0016052 carbohydrate catabolic process P 1 1 1 100 100 8 16 16 50 100 -0.059 1 1 0006812 cation transport P 1 2 2 50 100 10 20 20 50 100 -0.066 1 1 0008033 tRNA processing P 8 18 19 44.44444 94.73684 10 20 21 50 95.2381 -0.066 1 1 0008652 cellular amino acid biosynthetic process P 6 14 14 42.85714 100 10 20 21 50 95.2381 -0.066 1 1 0016746 transferase activity, transferring acyl groups F 9 18 18 50 100 11 22 22 50 100 -0.069 1 1 0008233 peptidase activity F 10 15 15 66.66666 100 12 24 24 50 100 -0.072 1 1 0071944 cell periphery C 0 0 0 0 0 19 38 38 50 100 -0.092 1 1 0034660 ncRNA metabolic process P 0 0 0 0 0 22 44 45 50 97.77778 -0.099 1 1