MAPPFinder 2.0 Results for the Gene Ontology File: C:\Users\keckuser\Desktop\20131119_teamATK_KM_compiledrawdata_GMAPP.gex Table: tATK_MAPPFinder_results-Criterion1-GO Database: C:\Users\keckuser\Downloads\20131125_E4_tATK_TIGR4.gdb colors:|12_hr| 11/25/2013 StreptococcusPneumoniaeTIGR4 Pvalues = true Calculation Summary: 1671 probes met the [Avg_logFC_12hr_all] < -0.25 AND [Pvalue_12hr] < 0.05 criteria. 1628 probes meeting the filter linked to a UniProt ID. 543 genes meeting the criterion linked to a GO term. 5022 Probes in this dataset 4689 Probes linked to a UniProt ID. 1044 Genes linked to a GO term. The z score is based on an N of 1044 and a R of 543 distinct genes in the GO. GOID GO Name GO Type Number Changed Local Number Measured Local Number in GO Local Percent Changed Local Percent Present Local Number Changed Number Measured Number in GO Percent Changed Percent Present Z Score PermuteP AdjustedP 0044424 intracellular part C 0 0 0 0 0 163 216 309 75.46296 69.90292 7.743 0 0 0009058 biosynthetic process P 17 23 35 73.91304 65.71429 213 303 445 70.29703 68.08989 7.559 0 0 0005622 intracellular C 33 40 63 82.5 63.49206 166 223 323 74.43946 69.04025 7.556 0 0 0005737 cytoplasm C 122 166 231 73.49397 71.86147 154 204 294 75.4902 69.38776 7.48 0 0 1901576 organic substance biosynthetic process P 0 0 0 0 0 205 292 427 70.20548 68.38407 7.329 0 0 0044249 cellular biosynthetic process P 0 1 2 0 50 199 285 419 69.82456 68.0191 7.056 0 0 0006412 translation P 56 60 95 93.33334 63.15789 57 61 98 93.44262 62.2449 6.672 0 0 0044267 cellular protein metabolic process P 0 1 1 0 100 70 81 129 86.41975 62.7907 6.451 0 0 0009059 macromolecule biosynthetic process P 1 1 1 100 100 130 177 255 73.44633 69.41177 6.261 0 0 0034645 cellular macromolecule biosynthetic process P 0 0 0 0 0 126 172 250 73.25581 68.8 6.099 0 0 0005623 cell C 0 0 0 0 0 215 330 476 65.15151 69.32773 5.775 0 0 0044464 cell part C 0 0 0 0 0 215 330 476 65.15151 69.32773 5.775 0 0 0019538 protein metabolic process P 1 1 1 100 100 84 108 170 77.77778 63.52941 5.658 0 0 0009987 cellular process P 1 2 3 50 66.66666 351 595 841 58.9916 70.74911 5.194 0 0 0005198 structural molecule activity F 0 0 0 0 0 31 33 55 93.93939 60 4.897 0 0 0003735 structural constituent of ribosome F 31 33 55 93.93939 60 31 33 55 93.93939 60 4.897 0 0 0044237 cellular metabolic process P 3 5 5 60 100 314 528 751 59.4697 70.30626 4.877 0 0 0003723 RNA binding F 46 61 89 75.40984 68.53933 58 73 105 79.45206 69.52381 4.864 0 0 0043226 organelle C 0 0 0 0 0 37 42 66 88.09524 63.63636 4.776 0 0 0043229 intracellular organelle C 0 0 0 0 0 37 42 66 88.09524 63.63636 4.776 0 0 0043232 intracellular non-membrane-bounded organelle C 0 0 0 0 0 37 42 66 88.09524 63.63636 4.776 0 0 0043228 non-membrane-bounded organelle C 0 0 0 0 0 37 42 66 88.09524 63.63636 4.776 0 0 0044260 cellular macromolecule metabolic process P 0 0 0 0 0 183 287 404 63.76307 71.0396 4.677 0 0 0010467 gene expression P 0 0 0 0 0 111 161 237 68.9441 67.93249 4.674 0 0 0043170 macromolecule metabolic process P 0 0 0 0 0 202 322 453 62.73292 71.08168 4.628 0 0 0016043 cellular component organization P 0 0 0 0 0 33 37 53 89.18919 69.81132 4.607 0 0 0030529 ribonucleoprotein complex C 32 34 55 94.11765 61.81818 32 36 58 88.88889 62.06897 4.505 0 0 0071840 cellular component organization or biogenesis P 0 0 0 0 0 46 57 80 80.70175 71.25 4.457 0 0 0071704 organic substance metabolic process P 0 0 0 0 0 333 572 814 58.21678 70.27027 4.416 0 0 0005840 ribosome C 31 35 57 88.57143 61.40351 31 35 57 88.57143 61.40351 4.402 0 0 0005488 binding F 0 0 0 0 0 344 594 833 57.91246 71.30853 4.383 0 0 0019843 rRNA binding F 23 24 38 95.83334 63.15789 23 24 38 95.83334 63.15789 4.345 0 0 0008152 metabolic process P 52 105 151 49.52381 69.53642 395 696 982 56.75287 70.87576 4.335 0 0 0016874 ligase activity F 34 40 56 85 71.42857 34 40 57 85 70.17544 4.256 0 0.001 0044238 primary metabolic process P 1 1 1 100 100 313 536 763 58.39552 70.24902 4.239 0 0.001 0044444 cytoplasmic part C 0 0 0 0 0 36 44 70 81.81818 62.85714 4.042 0 0.003 0006399 tRNA metabolic process P 0 0 0 0 0 29 34 47 85.29412 72.34042 3.947 0 0.003 0044710 single-organism metabolic process P 0 0 0 0 0 184 301 419 61.12957 71.83771 3.752 0 0.016 1901137 carbohydrate derivative biosynthetic process P 0 0 0 0 0 44 58 81 75.86207 71.60493 3.739 0 0.018 1901068 guanosine-containing compound metabolic process P 0 0 0 0 0 14 14 19 100 73.68421 3.617 0 0.034 0032991 macromolecular complex C 0 0 0 0 0 49 67 96 73.13433 69.79166 3.576 0 0.037 0034660 ncRNA metabolic process P 0 0 0 0 0 36 47 61 76.59574 77.04918 3.451 0 0.07 0046039 GTP metabolic process P 0 0 0 0 0 10 10 15 100 66.66666 3.051 0 0.266 0006952 defense response P 0 0 0 0 0 0 10 12 0 83.33334 -3.306 0 0.115 0008643 carbohydrate transport P 6 15 18 40 83.33334 10 41 57 24.39024 71.92982 -3.61 0 0.035 0009401 phosphoenolpyruvate-dependent sugar phosphotransferase system P 7 37 53 18.91892 69.81132 7 37 53 18.91892 69.81132 -4.101 0 0.002 0005215 transporter activity F 17 62 86 27.41936 72.09303 50 142 191 35.21127 74.34555 -4.309 0 0.001 0051234 establishment of localization P 0 0 0 0 0 66 181 244 36.46409 74.18033 -4.603 0 0 0051179 localization P 0 0 0 0 0 66 181 244 36.46409 74.18033 -4.603 0 0 0006810 transport P 42 127 170 33.07087 74.70588 66 181 244 36.46409 74.18033 -4.603 0 0 0032561 guanyl ribonucleotide binding F 0 0 0 0 0 16 17 26 94.11765 65.38461 3.502 0.001 0.057 0019001 guanyl nucleotide binding F 0 0 0 0 0 16 17 26 94.11765 65.38461 3.502 0.001 0.057 0005525 GTP binding F 16 17 26 94.11765 65.38461 16 17 26 94.11765 65.38461 3.502 0.001 0.057 0008610 lipid biosynthetic process P 0 0 1 0 0 20 23 30 86.95652 76.66666 3.39 0.001 0.079 0051128 regulation of cellular component organization P 0 0 0 0 0 15 16 24 93.75 66.66666 3.366 0.001 0.095 0016876 ligase activity, forming aminoacyl-tRNA and related compounds F 2 2 3 100 66.66666 15 16 24 93.75 66.66666 3.366 0.001 0.095 0016875 ligase activity, forming carbon-oxygen bonds F 0 0 0 0 0 15 16 24 93.75 66.66666 3.366 0.001 0.095 1901566 organonitrogen compound biosynthetic process P 0 0 0 0 0 71 106 161 66.98113 65.83851 3.253 0.001 0.129 0032989 cellular component morphogenesis P 0 0 0 0 0 14 15 21 93.33334 71.42857 3.225 0.001 0.146 0042546 cell wall biogenesis P 0 0 0 0 0 14 15 19 93.33334 78.94736 3.225 0.001 0.146 0022604 regulation of cell morphogenesis P 0 0 0 0 0 14 15 21 93.33334 71.42857 3.225 0.001 0.146 0070589 cellular component macromolecule biosynthetic process P 0 0 0 0 0 14 15 19 93.33334 78.94736 3.225 0.001 0.146 0044038 cell wall macromolecule biosynthetic process P 0 0 0 0 0 14 15 19 93.33334 78.94736 3.225 0.001 0.146 0000902 cell morphogenesis P 1 1 1 100 100 14 15 21 93.33334 71.42857 3.225 0.001 0.146 0008360 regulation of cell shape P 14 15 21 93.33334 71.42857 14 15 21 93.33334 71.42857 3.225 0.001 0.146 0050793 regulation of developmental process P 0 0 0 0 0 14 15 22 93.33334 68.18182 3.225 0.001 0.146 0009273 peptidoglycan-based cell wall biogenesis P 0 0 0 0 0 14 15 19 93.33334 78.94736 3.225 0.001 0.146 0022603 regulation of anatomical structure morphogenesis P 0 0 0 0 0 14 15 21 93.33334 71.42857 3.225 0.001 0.146 0005575 cellular_component C 0 0 0 0 0 258 448 625 57.58929 71.68 3.126 0.001 0.204 0043039 tRNA aminoacylation P 3 3 4 100 75 13 14 22 92.85714 63.63636 3.078 0.001 0.234 0043038 amino acid activation P 0 0 0 0 0 13 14 22 92.85714 63.63636 3.078 0.001 0.234 0006418 tRNA aminoacylation for protein translation P 11 12 18 91.66666 66.66666 13 14 22 92.85714 63.63636 3.078 0.001 0.234 0004812 aminoacyl-tRNA ligase activity F 13 14 22 92.85714 63.63636 13 14 22 92.85714 63.63636 3.078 0.001 0.234 0071554 cell wall organization or biogenesis P 0 0 0 0 0 14 16 23 87.5 69.56522 2.862 0.001 0.435 0044036 cell wall macromolecule metabolic process P 0 0 1 0 0 14 16 23 87.5 69.56522 2.862 0.001 0.435 0051707 response to other organism P 0 0 0 0 0 0 8 9 0 88.88889 -2.955 0.001 0.365 0009607 response to biotic stimulus P 0 0 0 0 0 0 8 9 0 88.88889 -2.955 0.001 0.365 0009617 response to bacterium P 0 0 0 0 0 0 8 9 0 88.88889 -2.955 0.001 0.365 0098542 defense response to other organism P 0 0 0 0 0 0 8 9 0 88.88889 -2.955 0.001 0.365 0042742 defense response to bacterium P 0 6 7 0 85.71429 0 8 9 0 88.88889 -2.955 0.001 0.365 0008982 protein-N(PI)-phosphohistidine-sugar phosphotransferase activity F 4 23 33 17.3913 69.69697 4 23 33 17.3913 69.69697 -3.359 0.001 0.095 0016020 membrane C 79 172 235 45.93023 73.19149 95 227 304 41.85022 74.67105 -3.462 0.001 0.069 0016773 phosphotransferase activity, alcohol group as acceptor F 2 6 7 33.33333 85.71429 16 55 76 29.09091 72.36842 -3.494 0.001 0.059 0000049 tRNA binding F 15 16 18 93.75 88.88889 15 16 18 93.75 88.88889 3.366 0.002 0.095 0006006 glucose metabolic process P 2 2 3 100 66.66666 12 12 18 100 66.66666 3.345 0.002 0.104 0044255 cellular lipid metabolic process P 0 0 0 0 0 21 25 33 84 75.75758 3.239 0.002 0.138 0006629 lipid metabolic process P 9 11 14 81.81818 78.57143 21 25 35 84 71.42857 3.239 0.002 0.138 0043436 oxoacid metabolic process P 0 0 0 0 0 53 77 120 68.83117 64.16666 3.068 0.002 0.236 0019752 carboxylic acid metabolic process P 0 0 0 0 0 53 77 120 68.83117 64.16666 3.068 0.002 0.236 1901476 carbohydrate transporter activity F 0 0 0 0 0 6 30 42 20 71.42857 -3.559 0.002 0.041 0015144 carbohydrate transmembrane transporter activity F 0 0 0 0 0 6 30 42 20 71.42857 -3.559 0.002 0.041 0043169 cation binding F 3 4 7 75 57.14286 88 137 189 64.23357 72.48677 3.071 0.003 0.236 1901564 organonitrogen compound metabolic process P 0 0 0 0 0 134 219 313 61.18721 69.96805 3.056 0.003 0.241 0006007 glucose catabolic process P 0 0 0 0 0 10 10 14 100 71.42857 3.051 0.003 0.266 0065008 regulation of biological quality P 0 0 0 0 0 23 29 42 79.31035 69.04762 2.983 0.003 0.323 0006023 aminoglycan biosynthetic process P 0 0 0 0 0 12 13 17 92.30769 76.47059 2.925 0.003 0.381 0009252 peptidoglycan biosynthetic process P 12 13 17 92.30769 76.47059 12 13 17 92.30769 76.47059 2.925 0.003 0.381 0006024 glycosaminoglycan biosynthetic process P 0 0 0 0 0 12 13 17 92.30769 76.47059 2.925 0.003 0.381 0043167 ion binding F 0 0 0 0 0 201 344 464 58.43023 74.13793 2.909 0.003 0.386 0044767 single-organism developmental process P 0 0 0 0 0 14 16 23 87.5 69.56522 2.862 0.003 0.435 0048856 anatomical structure development P 0 0 0 0 0 14 16 22 87.5 72.72727 2.862 0.003 0.435 0009653 anatomical structure morphogenesis P 0 0 0 0 0 14 16 22 87.5 72.72727 2.862 0.003 0.435 0032502 developmental process P 0 0 0 0 0 14 16 23 87.5 69.56522 2.862 0.003 0.435 0048869 cellular developmental process P 0 0 0 0 0 14 16 22 87.5 72.72727 2.862 0.003 0.435 0005515 protein binding F 72 105 159 68.57143 66.03773 76 115 174 66.08696 66.09196 3.201 0.004 0.163 0006082 organic acid metabolic process P 0 1 1 0 100 55 81 124 67.90124 65.32258 2.979 0.004 0.329 0044085 cellular component biogenesis P 0 0 0 0 0 30 40 56 75 71.42857 2.966 0.004 0.333 0006520 cellular amino acid metabolic process P 1 2 6 50 33.33333 44 63 99 69.84127 63.63636 2.921 0.004 0.381 0006184 GTP catabolic process P 9 9 14 100 64.28571 9 9 14 100 64.28571 2.893 0.004 0.405 1901069 guanosine-containing compound catabolic process P 0 0 0 0 0 9 9 14 100 64.28571 2.893 0.004 0.405 0003924 GTPase activity F 9 9 14 100 64.28571 9 9 14 100 64.28571 2.893 0.004 0.405 0016051 carbohydrate biosynthetic process P 1 1 1 100 100 16 19 22 84.21053 86.36364 2.834 0.004 0.476 0016879 ligase activity, forming carbon-nitrogen bonds F 1 1 1 100 100 16 20 27 80 74.07407 2.529 0.004 0.858 0015294 solute:cation symporter activity F 0 0 0 0 0 5 24 31 20.83333 77.41936 -3.092 0.004 0.224 0044281 small molecule metabolic process P 0 0 0 0 0 137 227 326 60.35242 69.6319 2.842 0.005 0.471 0015293 symporter activity F 0 0 0 0 0 6 25 32 24 78.125 -2.836 0.005 0.471 0051119 sugar transmembrane transporter activity F 0 0 0 0 0 5 23 30 21.73913 76.66666 -2.937 0.005 0.367 0004553 hydrolase activity, hydrolyzing O-glycosyl compounds F 4 17 20 23.52941 85 5 24 32 20.83333 75 -3.092 0.005 0.224 0097159 organic cyclic compound binding F 0 0 0 0 0 245 427 588 57.37705 72.61905 2.885 0.006 0.406 0008033 tRNA processing P 15 18 20 83.33334 90 17 21 26 80.95238 80.76923 2.68 0.006 0.657 0022804 active transmembrane transporter activity F 0 0 0 0 0 24 67 89 35.8209 75.2809 -2.741 0.006 0.573 0009169 purine ribonucleoside monophosphate catabolic process P 0 0 0 0 0 22 63 77 34.92064 81.81818 -2.8 0.006 0.496 0009158 ribonucleoside monophosphate catabolic process P 0 0 0 0 0 22 63 77 34.92064 81.81818 -2.8 0.006 0.496 0009125 nucleoside monophosphate catabolic process P 0 0 0 0 0 22 63 77 34.92064 81.81818 -2.8 0.006 0.496 0009128 purine nucleoside monophosphate catabolic process P 0 0 0 0 0 22 63 77 34.92064 81.81818 -2.8 0.006 0.496 0006200 ATP catabolic process P 22 63 77 34.92064 81.81818 22 63 77 34.92064 81.81818 -2.8 0.006 0.496 0046496 nicotinamide nucleotide metabolic process P 0 0 0 0 0 9 9 10 100 90 2.893 0.007 0.405 0019362 pyridine nucleotide metabolic process P 0 0 0 0 0 9 9 10 100 90 2.893 0.007 0.405 0072524 pyridine-containing compound metabolic process P 0 0 0 0 0 9 9 10 100 90 2.893 0.007 0.405 0006733 oxidoreduction coenzyme metabolic process P 0 0 0 0 0 9 9 10 100 90 2.893 0.007 0.405 0007049 cell cycle P 15 18 30 83.33334 60 16 19 31 84.21053 61.29032 2.834 0.007 0.476 0036094 small molecule binding F 1 1 1 100 100 154 261 350 59.00383 74.57143 2.61 0.007 0.719 0006304 DNA modification P 1 9 9 11.11111 100 2 14 17 14.28571 82.35294 -2.843 0.007 0.471 0044422 organelle part C 0 0 0 0 0 8 8 16 100 50 2.726 0.008 0.613 0008135 translation factor activity, nucleic acid binding F 0 0 0 0 0 8 8 12 100 66.66666 2.726 0.008 0.613 0044446 intracellular organelle part C 0 0 0 0 0 8 8 16 100 50 2.726 0.008 0.613 0044425 membrane part C 0 0 0 0 0 60 144 197 41.66667 73.09644 -2.675 0.008 0.66 0046872 metal ion binding F 70 111 149 63.06306 74.49664 83 131 180 63.35878 72.77778 2.779 0.009 0.498 0015291 secondary active transmembrane transporter activity F 0 0 0 0 0 10 34 43 29.41176 79.06977 -2.68 0.009 0.66 0005402 cation:sugar symporter activity F 0 0 0 0 0 5 22 29 22.72727 75.86207 -2.777 0.009 0.499 0015295 solute:hydrogen symporter activity F 0 0 0 0 0 5 22 29 22.72727 75.86207 -2.777 0.009 0.499 0005351 sugar:hydrogen symporter activity F 4 21 28 19.04762 75 5 22 29 22.72727 75.86207 -2.777 0.009 0.499 1901363 heterocyclic compound binding F 0 0 0 0 0 243 425 586 57.17647 72.5256 2.767 0.01 0.501 0044711 single-organism biosynthetic process P 0 0 0 0 0 42 62 95 67.74194 65.26316 2.555 0.011 0.82 0016053 organic acid biosynthetic process P 0 0 0 0 0 37 53 79 69.81132 67.08861 2.661 0.012 0.693 0004672 protein kinase activity F 0 2 5 0 40 2 12 19 16.66667 63.15789 -2.464 0.013 0.903 0044275 cellular carbohydrate catabolic process P 0 0 0 0 0 0 6 9 0 66.66666 -2.556 0.013 0.82 0006400 tRNA modification P 6 6 6 100 100 13 16 19 81.25 84.21053 2.358 0.014 0.969 0071702 organic substance transport P 0 0 0 0 0 22 63 91 34.92064 69.23077 -2.8 0.014 0.496 0044391 ribosomal subunit C 0 0 0 0 0 7 7 14 100 50 2.549 0.015 0.848 0016021 integral to membrane C 54 130 182 41.53846 71.42857 54 130 182 41.53846 71.42857 -2.553 0.015 0.821 0051301 cell division P 14 17 29 82.35294 58.62069 14 17 29 82.35294 58.62069 2.523 0.018 0.863 0044283 small molecule biosynthetic process P 0 0 0 0 0 40 60 93 66.66666 64.51613 2.339 0.018 0.97 0031224 intrinsic to membrane C 0 0 0 0 0 55 131 183 41.98473 71.5847 -2.455 0.018 0.905 0006807 nitrogen compound metabolic process P 2 2 4 100 50 226 398 551 56.78392 72.23231 2.422 0.019 0.907 0016798 hydrolase activity, acting on glycosyl bonds F 5 13 21 38.46154 61.90476 8 27 38 29.62963 71.05264 -2.357 0.019 0.969 0000155 phosphorelay sensor kinase activity F 1 9 13 11.11111 69.23077 1 9 13 11.11111 69.23077 -2.465 0.019 0.893 0004872 receptor activity F 0 0 0 0 0 1 9 13 11.11111 69.23077 -2.465 0.019 0.893 0038023 signaling receptor activity F 0 0 0 0 0 1 9 13 11.11111 69.23077 -2.465 0.019 0.893 0023014 signal transduction by phosphorylation P 1 9 13 11.11111 69.23077 1 9 13 11.11111 69.23077 -2.465 0.019 0.893 0004673 protein histidine kinase activity F 0 2 2 0 100 1 9 13 11.11111 69.23077 -2.465 0.019 0.893 0046034 ATP metabolic process P 2 4 4 50 100 27 71 88 38.02817 80.68182 -2.442 0.02 0.905 0009126 purine nucleoside monophosphate metabolic process P 0 0 0 0 0 32 80 103 40 77.66991 -2.237 0.023 0.994 0009167 purine ribonucleoside monophosphate metabolic process P 0 0 0 0 0 32 80 103 40 77.66991 -2.237 0.023 0.994 0022857 transmembrane transporter activity F 1 1 1 100 100 36 90 116 40 77.5862 -2.385 0.023 0.927 0006096 glycolysis P 6 6 10 100 60 6 6 10 100 60 2.359 0.026 0.969 0006396 RNA processing P 6 10 10 60 100 27 39 45 69.23077 86.66666 2.193 0.027 0.996 0051704 multi-organism process P 0 0 0 0 0 8 25 30 32 83.33334 -2.026 0.027 1 0046394 carboxylic acid biosynthetic process P 0 0 0 0 0 35 51 77 68.62745 66.23376 2.434 0.028 0.905 0090407 organophosphate biosynthetic process P 0 0 0 0 0 39 59 84 66.10169 70.2381 2.229 0.029 0.994 0034470 ncRNA processing P 0 0 0 0 0 24 34 40 70.58823 85 2.203 0.029 0.995 0016627 oxidoreductase activity, acting on the CH-CH group of donors F 0 0 0 0 0 6 6 7 100 85.71429 2.359 0.03 0.969 0006022 aminoglycan metabolic process P 0 0 0 0 0 12 15 20 80 75 2.184 0.03 0.996 0000270 peptidoglycan metabolic process P 0 0 0 0 0 12 15 20 80 75 2.184 0.03 0.996 0030203 glycosaminoglycan metabolic process P 0 0 0 0 0 12 15 20 80 75 2.184 0.03 0.996 1901293 nucleoside phosphate biosynthetic process P 0 0 0 0 0 28 41 62 68.29269 66.12904 2.128 0.03 0.999 0009165 nucleotide biosynthetic process P 1 3 6 33.33333 50 28 41 62 68.29269 66.12904 2.128 0.03 0.999 0006732 coenzyme metabolic process P 0 0 0 0 0 23 32 39 71.875 82.05128 2.283 0.031 0.987 0003674 molecular_function F 0 0 0 0 0 501 943 1335 53.12831 70.6367 2.206 0.035 0.995 0006739 NADP metabolic process P 0 0 0 0 0 6 6 6 100 100 2.359 0.036 0.969 0046365 monosaccharide catabolic process P 0 0 0 0 0 10 12 17 83.33334 70.58823 2.183 0.036 0.996 0019320 hexose catabolic process P 0 0 0 0 0 10 12 17 83.33334 70.58823 2.183 0.036 0.996 0006633 fatty acid biosynthetic process P 8 9 12 88.88889 75 8 9 12 88.88889 75 2.223 0.039 0.995 0072330 monocarboxylic acid biosynthetic process P 0 0 0 0 0 8 9 12 88.88889 75 2.223 0.039 0.995 0006631 fatty acid metabolic process P 4 5 6 80 83.33334 8 9 12 88.88889 75 2.223 0.039 0.995 0006725 cellular aromatic compound metabolic process P 1 1 1 100 100 200 354 483 56.49717 73.29192 2.077 0.039 0.999 0043168 anion binding F 0 0 0 0 0 146 254 335 57.48032 75.82089 2.005 0.049 1 1901360 organic cyclic compound metabolic process P 0 0 0 0 0 201 357 491 56.30252 72.70876 2 0.049 1 0009161 ribonucleoside monophosphate metabolic process P 0 0 0 0 0 36 86 116 41.86047 74.13793 -1.966 0.05 1 0044763 single-organism cellular process P 0 0 0 0 0 101 172 233 58.72093 73.81974 1.926 0.053 1 0006555 methionine metabolic process P 0 1 1 0 100 0 4 7 0 57.14286 -2.085 0.053 0.999 0009086 methionine biosynthetic process P 0 4 7 0 57.14286 0 4 7 0 57.14286 -2.085 0.053 0.999 0042578 phosphoric ester hydrolase activity F 0 0 0 0 0 5 5 7 100 71.42857 2.152 0.054 0.999 0016833 oxo-acid-lyase activity F 0 1 1 0 100 0 4 5 0 80 -2.085 0.054 0.999 0016775 phosphotransferase activity, nitrogenous group as acceptor F 0 0 0 0 0 2 10 14 20 71.42857 -2.035 0.055 1 0044765 single-organism transport P 0 0 0 0 0 52 120 163 43.33333 73.61963 -2.022 0.056 1 0009313 oligosaccharide catabolic process P 0 0 0 0 0 0 4 7 0 57.14286 -2.085 0.057 0.999 0046352 disaccharide catabolic process P 0 0 0 0 0 0 4 7 0 57.14286 -2.085 0.057 0.999 0005990 lactose catabolic process P 0 2 4 0 50 0 4 6 0 66.66666 -2.085 0.057 0.999 0005984 disaccharide metabolic process P 0 0 0 0 0 0 4 9 0 44.44444 -2.085 0.057 0.999 0005988 lactose metabolic process P 0 3 5 0 60 0 4 7 0 57.14286 -2.085 0.057 0.999 0042221 response to chemical stimulus P 0 0 0 0 0 11 14 18 78.57143 77.77778 2.002 0.058 1 1901265 nucleoside phosphate binding F 0 0 0 0 0 143 249 334 57.42972 74.5509 1.96 0.058 1 0000166 nucleotide binding F 111 197 265 56.34518 74.33962 143 249 334 57.42972 74.5509 1.96 0.058 1 0004022 alcohol dehydrogenase (NAD) activity F 0 4 4 0 100 0 4 4 0 100 -2.085 0.058 0.999 0009225 nucleotide-sugar metabolic process P 1 1 1 100 100 5 5 7 100 71.42857 2.152 0.059 0.999 0051186 cofactor metabolic process P 0 0 0 0 0 24 35 42 68.57143 83.33334 1.994 0.059 1 0016887 ATPase activity F 22 63 77 34.92064 81.81818 36 85 111 42.35294 76.57658 -1.859 0.061 1 0009103 lipopolysaccharide biosynthetic process P 5 5 5 100 100 5 5 5 100 100 2.152 0.062 0.999 0008653 lipopolysaccharide metabolic process P 0 0 0 0 0 5 5 5 100 100 2.152 0.062 0.999 0046677 response to antibiotic P 7 8 12 87.5 66.66666 7 8 12 87.5 66.66666 2.016 0.064 1 0009636 response to toxic substance P 0 0 0 0 0 7 8 12 87.5 66.66666 2.016 0.064 1 0034641 cellular nitrogen compound metabolic process P 0 0 0 0 0 198 353 483 56.09065 73.08488 1.885 0.064 1 0006098 pentose-phosphate shunt P 5 5 5 100 100 5 5 5 100 100 2.152 0.066 0.999 0006740 NADPH regeneration P 0 0 0 0 0 5 5 5 100 100 2.152 0.066 0.999 0003676 nucleic acid binding F 17 36 51 47.22222 70.58823 124 214 310 57.94392 69.03226 1.947 0.066 1 1901565 organonitrogen compound catabolic process P 0 0 0 0 0 33 78 101 42.30769 77.22772 -1.782 0.066 1 0032787 monocarboxylic acid metabolic process P 0 0 0 0 0 9 11 16 81.81818 68.75 1.988 0.067 1 0000271 polysaccharide biosynthetic process P 7 8 8 87.5 100 11 14 16 78.57143 87.5 2.002 0.068 1 0009123 nucleoside monophosphate metabolic process P 0 0 0 0 0 37 87 117 42.52874 74.35897 -1.848 0.069 1 0006012 galactose metabolic process P 1 6 6 16.66667 100 1 7 8 14.28571 87.5 -2.004 0.069 1 0009396 folic acid-containing compound biosynthetic process P 6 7 8 85.71429 87.5 7 8 10 87.5 80 2.016 0.07 1 0006760 folic acid-containing compound metabolic process P 0 0 1 0 0 7 8 11 87.5 72.72727 2.016 0.07 1 1901136 carbohydrate derivative catabolic process P 0 0 0 0 0 34 80 105 42.5 76.19048 -1.771 0.07 1 0048037 cofactor binding F 0 1 2 0 50 29 44 57 65.90909 77.19299 1.884 0.082 1 0046914 transition metal ion binding F 0 0 1 0 0 28 43 66 65.11628 65.15151 1.756 0.082 1 0022891 substrate-specific transmembrane transporter activity F 0 0 0 0 0 27 66 88 40.90909 75 -1.864 0.083 1 0016853 isomerase activity F 21 30 51 70 58.82353 23 34 56 67.64706 60.71429 1.854 0.084 1 0045259 proton-transporting ATP synthase complex C 0 0 0 0 0 5 5 8 100 62.5 2.152 0.091 0.999 0046483 heterocycle metabolic process P 0 0 0 0 0 197 353 481 55.80737 73.38877 1.754 0.092 1 0007154 cell communication P 0 0 0 0 0 14 37 46 37.83784 80.43478 -1.756 0.094 1 0004803 transposase activity F 1 6 8 16.66667 75 1 6 8 16.66667 75 -1.737 0.098 1 0008654 phospholipid biosynthetic process P 5 7 7 71.42857 100 8 10 11 80 90.90909 1.779 0.1 1 0006575 cellular modified amino acid metabolic process P 0 0 0 0 0 8 10 15 80 66.66666 1.779 0.101 1 0042398 cellular modified amino acid biosynthetic process P 0 0 0 0 0 8 10 13 80 76.92308 1.779 0.101 1 0016772 transferase activity, transferring phosphorus-containing groups F 4 10 14 40 71.42857 45 102 139 44.11765 73.38129 -1.679 0.102 1 0019512 lactose catabolic process via tagatose-6-phosphate P 0 3 4 0 75 0 3 4 0 75 -1.805 0.108 1 0006139 nucleobase-containing compound metabolic process P 4 5 7 80 71.42857 183 328 444 55.79268 73.87387 1.654 0.109 1 0015980 energy derivation by oxidation of organic compounds P 0 0 0 0 0 0 3 5 0 60 -1.805 0.11 1 0005506 iron ion binding F 3 3 6 100 50 4 4 7 100 57.14286 1.924 0.111 1 0009163 nucleoside biosynthetic process P 0 0 0 0 0 19 28 41 67.85714 68.29269 1.7 0.111 1 0042455 ribonucleoside biosynthetic process P 0 0 0 0 0 19 28 41 67.85714 68.29269 1.7 0.111 1 1901659 glycosyl compound biosynthetic process P 0 0 0 0 0 19 28 41 67.85714 68.29269 1.7 0.111 1 0044282 small molecule catabolic process P 0 0 0 0 0 1 6 10 16.66667 60 -1.737 0.114 1 0044712 single-organism catabolic process P 0 0 0 0 0 1 6 10 16.66667 60 -1.737 0.114 1 0022892 substrate-specific transporter activity F 0 0 0 0 0 28 67 90 41.79105 74.44444 -1.73 0.116 1 0043177 organic acid binding F 0 0 0 0 0 6 7 13 85.71429 53.84615 1.79 0.117 1 0031406 carboxylic acid binding F 0 0 0 0 0 6 7 13 85.71429 53.84615 1.79 0.117 1 0019438 aromatic compound biosynthetic process P 0 0 0 0 0 76 129 196 58.91473 65.81633 1.676 0.117 1 0030001 metal ion transport P 4 5 5 80 100 8 10 11 80 90.90909 1.779 0.118 1 0033692 cellular polysaccharide biosynthetic process P 0 0 0 0 0 8 10 12 80 83.33334 1.779 0.121 1 0034637 cellular carbohydrate biosynthetic process P 0 0 0 0 0 8 10 12 80 83.33334 1.779 0.121 1 0015935 small ribosomal subunit C 4 4 7 100 57.14286 4 4 7 100 57.14286 1.924 0.123 1 0044723 single-organism carbohydrate metabolic process P 0 0 0 0 0 27 42 58 64.28571 72.4138 1.624 0.124 1 0008652 cellular amino acid biosynthetic process P 13 22 41 59.09091 53.65854 27 42 65 64.28571 64.61539 1.624 0.125 1 1901362 organic cyclic compound biosynthetic process P 0 0 0 0 0 78 133 206 58.64662 64.56311 1.639 0.127 1 0046379 extracellular polysaccharide metabolic process P 0 0 0 0 0 4 4 4 100 100 1.924 0.128 1 0045229 external encapsulating structure organization P 0 0 0 0 0 4 4 4 100 100 1.924 0.128 1 0045226 extracellular polysaccharide biosynthetic process P 0 0 0 0 0 4 4 4 100 100 1.924 0.128 1 0045230 capsule organization P 0 0 0 0 0 4 4 4 100 100 1.924 0.128 1 0045227 capsule polysaccharide biosynthetic process P 4 4 4 100 100 4 4 4 100 100 1.924 0.128 1 0016881 acid-amino acid ligase activity F 1 1 1 100 100 6 7 8 85.71429 87.5 1.79 0.128 1 0005976 polysaccharide metabolic process P 0 0 0 0 0 11 15 17 73.33334 88.23529 1.664 0.128 1 0006415 translational termination P 4 4 4 100 100 4 4 4 100 100 1.924 0.131 1 0022411 cellular component disassembly P 0 0 0 0 0 4 4 6 100 66.66666 1.924 0.131 1 0043241 protein complex disassembly P 0 0 0 0 0 4 4 6 100 66.66666 1.924 0.131 1 0032984 macromolecular complex disassembly P 0 0 0 0 0 4 4 6 100 66.66666 1.924 0.131 1 0043624 cellular protein complex disassembly P 0 0 0 0 0 4 4 4 100 100 1.924 0.131 1 0016769 transferase activity, transferring nitrogenous groups F 0 0 0 0 0 6 7 9 85.71429 77.77778 1.79 0.132 1 0008483 transaminase activity F 6 7 9 85.71429 77.77778 6 7 9 85.71429 77.77778 1.79 0.132 1 0006260 DNA replication P 17 25 27 68 92.59259 19 28 31 67.85714 90.32258 1.7 0.132 1 0055086 nucleobase-containing small molecule metabolic process P 0 0 0 0 0 80 138 188 57.97102 73.40426 1.504 0.133 1 0019674 NAD metabolic process P 1 1 1 100 100 4 4 5 100 80 1.924 0.135 1 0019363 pyridine nucleotide biosynthetic process P 2 2 3 100 66.66666 4 4 5 100 80 1.924 0.135 1 0019359 nicotinamide nucleotide biosynthetic process P 0 0 0 0 0 4 4 5 100 80 1.924 0.135 1 0072525 pyridine-containing compound biosynthetic process P 0 0 0 0 0 4 4 5 100 80 1.924 0.135 1 1901135 carbohydrate derivative metabolic process P 0 0 0 0 0 88 152 206 57.89474 73.78641 1.57 0.135 1 0050662 coenzyme binding F 4 7 10 57.14286 70 19 28 38 67.85714 73.68421 1.7 0.136 1 0050661 NADP binding F 6 7 12 85.71429 58.33333 6 7 12 85.71429 58.33333 1.79 0.138 1 0016788 hydrolase activity, acting on ester bonds F 5 7 9 71.42857 77.77778 30 48 63 62.5 76.19048 1.488 0.141 1 0032196 transposition P 0 0 0 0 0 2 8 10 25 80 -1.534 0.143 1 0006313 transposition, DNA-mediated P 2 8 10 25 80 2 8 10 25 80 -1.534 0.143 1 0006152 purine nucleoside catabolic process P 0 0 0 0 0 31 72 91 43.05556 79.12088 -1.576 0.143 1 0009261 ribonucleotide catabolic process P 0 0 0 0 0 31 72 91 43.05556 79.12088 -1.576 0.143 1 0046130 purine ribonucleoside catabolic process P 0 0 0 0 0 31 72 91 43.05556 79.12088 -1.576 0.143 1 0072523 purine-containing compound catabolic process P 0 0 0 0 0 31 72 91 43.05556 79.12088 -1.576 0.143 1 0009154 purine ribonucleotide catabolic process P 0 0 0 0 0 31 72 91 43.05556 79.12088 -1.576 0.143 1 0006195 purine nucleotide catabolic process P 0 0 0 0 0 31 72 91 43.05556 79.12088 -1.576 0.143 1 0009207 purine ribonucleoside triphosphate catabolic process P 0 0 0 0 0 31 72 91 43.05556 79.12088 -1.576 0.143 1 0009203 ribonucleoside triphosphate catabolic process P 0 0 0 0 0 31 72 91 43.05556 79.12088 -1.576 0.143 1 0009146 purine nucleoside triphosphate catabolic process P 0 0 0 0 0 31 72 91 43.05556 79.12088 -1.576 0.143 1 0045261 proton-transporting ATP synthase complex, catalytic core F(1) C 4 4 5 100 80 4 4 5 100 80 1.924 0.146 1 0046434 organophosphate catabolic process P 0 0 0 0 0 34 77 98 44.15585 78.57143 -1.433 0.148 1 0016070 RNA metabolic process P 1 2 2 50 100 69 118 168 58.47458 70.2381 1.491 0.153 1 0006221 pyrimidine nucleotide biosynthetic process P 4 6 11 66.66666 54.54546 7 9 16 77.77778 56.25 1.553 0.156 1 0008324 cation transmembrane transporter activity F 4 6 7 66.66666 85.71429 19 47 60 40.42553 78.33334 -1.626 0.157 1 0043933 macromolecular complex subunit organization P 0 0 0 0 0 9 12 16 75 75 1.602 0.161 1 0009108 coenzyme biosynthetic process P 0 0 0 0 0 18 27 32 66.66666 84.375 1.544 0.165 1 0044271 cellular nitrogen compound biosynthetic process P 0 0 0 0 0 75 129 198 58.13953 65.15151 1.487 0.168 1 0046131 pyrimidine ribonucleoside metabolic process P 0 0 0 0 0 7 9 15 77.77778 60 1.553 0.17 1 0042454 ribonucleoside catabolic process P 0 0 0 0 0 32 73 92 43.83562 79.34782 -1.449 0.173 1 0009164 nucleoside catabolic process P 0 0 1 0 0 32 73 93 43.83562 78.49462 -1.449 0.173 1 1901658 glycosyl compound catabolic process P 0 0 0 0 0 32 73 93 43.83562 78.49462 -1.449 0.173 1 0044248 cellular catabolic process P 0 0 0 0 0 39 87 116 44.82759 75 -1.4 0.174 1 0042558 pteridine-containing compound metabolic process P 1 1 1 100 100 7 9 12 77.77778 75 1.553 0.175 1 0042559 pteridine-containing compound biosynthetic process P 0 0 0 0 0 7 9 11 77.77778 81.81818 1.553 0.175 1 0042451 purine nucleoside biosynthetic process P 0 0 0 0 0 13 19 25 68.42105 76 1.444 0.176 1 0046129 purine ribonucleoside biosynthetic process P 0 0 0 0 0 13 19 25 68.42105 76 1.444 0.176 1 0009143 nucleoside triphosphate catabolic process P 1 1 1 100 100 32 73 92 43.83562 79.34782 -1.449 0.181 1 0017076 purine nucleotide binding F 0 0 0 0 0 124 221 295 56.1086 74.91525 1.372 0.182 1 0015926 glucosidase activity F 0 0 0 0 0 1 5 5 20 100 -1.436 0.182 1 0009166 nucleotide catabolic process P 0 0 1 0 0 32 73 93 43.83562 78.49462 -1.449 0.182 1 0071103 DNA conformation change P 0 0 0 0 0 7 9 10 77.77778 90 1.553 0.186 1 0001071 nucleic acid binding transcription factor activity F 0 0 0 0 0 11 28 46 39.28571 60.86956 -1.366 0.19 1 0003700 sequence-specific DNA binding transcription factor activity F 11 28 46 39.28571 60.86956 11 28 46 39.28571 60.86956 -1.366 0.19 1 0043650 dicarboxylic acid biosynthetic process P 0 0 0 0 0 7 9 15 77.77778 60 1.553 0.193 1 0046395 carboxylic acid catabolic process P 0 0 0 0 0 1 5 9 20 55.55556 -1.436 0.193 1 0016054 organic acid catabolic process P 0 0 0 0 0 1 5 9 20 55.55556 -1.436 0.193 1 0005694 chromosome C 4 5 6 80 83.33334 5 6 7 83.33334 85.71429 1.539 0.194 1 0043190 ATP-binding cassette (ABC) transporter complex C 1 5 5 20 100 1 5 5 20 100 -1.436 0.194 1 1902495 transmembrane transporter complex C 0 0 0 0 0 1 5 5 20 100 -1.436 0.194 1 0098533 ATPase dependent transmembrane transport complex C 0 0 0 0 0 1 5 5 20 100 -1.436 0.194 1 0000097 sulfur amino acid biosynthetic process P 0 0 0 0 0 1 5 9 20 55.55556 -1.436 0.196 1 0000096 sulfur amino acid metabolic process P 0 0 0 0 0 1 5 10 20 50 -1.436 0.196 1 0045184 establishment of protein localization P 0 0 0 0 0 10 14 22 71.42857 63.63636 1.463 0.2 1 0015031 protein transport P 6 10 17 60 58.82353 10 14 22 71.42857 63.63636 1.463 0.2 1 0033036 macromolecule localization P 0 0 0 0 0 10 14 22 71.42857 63.63636 1.463 0.2 1 0008104 protein localization P 0 0 0 0 0 10 14 22 71.42857 63.63636 1.463 0.2 1 0006468 protein phosphorylation P 0 2 5 0 40 1 5 8 20 62.5 -1.436 0.203 1 0009260 ribonucleotide biosynthetic process P 0 0 0 0 0 20 31 46 64.51613 67.3913 1.414 0.205 1 0097367 carbohydrate derivative binding F 0 0 0 0 0 124 222 294 55.85585 75.5102 1.291 0.206 1 0008150 biological_process P 0 0 0 0 0 459 868 1211 52.88018 71.6763 1.247 0.206 1 0006085 acetyl-CoA biosynthetic process P 0 1 1 0 100 0 2 2 0 100 -1.473 0.206 1 0009098 leucine biosynthetic process P 0 2 3 0 66.66666 0 2 3 0 66.66666 -1.473 0.206 1 0071616 acyl-CoA biosynthetic process P 0 0 0 0 0 0 2 2 0 100 -1.473 0.206 1 0006637 acyl-CoA metabolic process P 0 0 0 0 0 0 2 2 0 100 -1.473 0.206 1 0006084 acetyl-CoA metabolic process P 0 0 0 0 0 0 2 2 0 100 -1.473 0.206 1 0035383 thioester metabolic process P 0 0 0 0 0 0 2 2 0 100 -1.473 0.206 1 0035384 thioester biosynthetic process P 0 0 0 0 0 0 2 2 0 100 -1.473 0.206 1 0006551 leucine metabolic process P 0 0 0 0 0 0 2 3 0 66.66666 -1.473 0.206 1 0016646 oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor F 0 0 0 0 0 1 5 6 20 83.33334 -1.436 0.207 1 0016645 oxidoreductase activity, acting on the CH-NH group of donors F 0 0 0 0 0 1 5 6 20 83.33334 -1.436 0.207 1 0007165 signal transduction P 2 9 12 22.22222 75 9 24 31 37.5 77.41936 -1.439 0.208 1 0044700 single organism signaling P 0 0 0 0 0 9 24 31 37.5 77.41936 -1.439 0.208 1 0023052 signaling P 0 0 0 0 0 9 24 31 37.5 77.41936 -1.439 0.208 1 0004049 anthranilate synthase activity F 0 2 2 0 100 0 2 2 0 100 -1.473 0.208 1 0036211 protein modification process P 0 0 0 0 0 11 16 24 68.75 66.66666 1.35 0.209 1 0006464 cellular protein modification process P 0 0 2 0 0 11 16 24 68.75 66.66666 1.35 0.209 1 0009432 SOS response P 1 5 7 20 71.42857 1 5 7 20 71.42857 -1.436 0.209 1 0016774 phosphotransferase activity, carboxyl group as acceptor F 0 1 1 0 100 0 2 5 0 40 -1.473 0.21 1 0051539 4 iron, 4 sulfur cluster binding F 5 6 8 83.33334 75 5 6 8 83.33334 75 1.539 0.211 1 0072348 sulfur compound transport P 0 0 0 0 0 0 2 2 0 100 -1.473 0.212 1 0009097 isoleucine biosynthetic process P 1 5 7 20 71.42857 1 5 7 20 71.42857 -1.436 0.215 1 0006549 isoleucine metabolic process P 0 0 0 0 0 1 5 7 20 71.42857 -1.436 0.215 1 0004575 sucrose alpha-glucosidase activity F 0 2 2 0 100 0 2 2 0 100 -1.473 0.216 1 0004564 beta-fructofuranosidase activity F 0 2 2 0 100 0 2 2 0 100 -1.473 0.216 1 0046148 pigment biosynthetic process P 0 0 0 0 0 0 2 4 0 50 -1.473 0.217 1 0042440 pigment metabolic process P 0 0 0 0 0 0 2 4 0 50 -1.473 0.217 1 0016758 transferase activity, transferring hexosyl groups F 1 1 1 100 100 1 5 7 20 71.42857 -1.436 0.219 1 0018202 peptidyl-histidine modification P 0 0 0 0 0 0 2 2 0 100 -1.473 0.219 1 0018106 peptidyl-histidine phosphorylation P 0 2 2 0 100 0 2 2 0 100 -1.473 0.219 1 0006644 phospholipid metabolic process P 2 2 2 100 100 8 11 13 72.72727 84.61539 1.382 0.222 1 0008747 N-acetylneuraminate lyase activity F 0 2 2 0 100 0 2 2 0 100 -1.473 0.222 1 1901292 nucleoside phosphate catabolic process P 0 0 0 0 0 33 74 94 44.59459 78.7234 -1.324 0.223 1 0008234 cysteine-type peptidase activity F 0 2 3 0 66.66666 0 2 4 0 50 -1.473 0.223 1 0017004 cytochrome complex assembly P 0 2 2 0 100 0 2 2 0 100 -1.473 0.223 1 0004645 phosphorylase activity F 0 2 2 0 100 0 2 3 0 66.66666 -1.473 0.225 1 0044355 clearance of foreign intracellular DNA P 0 0 0 0 0 0 2 3 0 66.66666 -1.473 0.226 1 0004789 thiamine-phosphate diphosphorylase activity F 0 2 2 0 100 0 2 2 0 100 -1.473 0.226 1 0009307 DNA restriction-modification system P 0 2 3 0 66.66666 0 2 3 0 66.66666 -1.473 0.226 1 2001058 D-tagatose 6-phosphate metabolic process P 0 0 0 0 0 0 2 3 0 66.66666 -1.473 0.228 1 0015928 fucosidase activity F 0 0 0 0 0 0 2 3 0 66.66666 -1.473 0.228 1 0008422 beta-glucosidase activity F 0 0 0 0 0 0 2 2 0 100 -1.473 0.228 1 0009024 tagatose-6-phosphate kinase activity F 0 2 3 0 66.66666 0 2 3 0 66.66666 -1.473 0.228 1 0008706 6-phospho-beta-glucosidase activity F 0 2 2 0 100 0 2 2 0 100 -1.473 0.228 1 2001059 D-tagatose 6-phosphate catabolic process P 0 2 3 0 66.66666 0 2 3 0 66.66666 -1.473 0.228 1 0004560 alpha-L-fucosidase activity F 0 2 3 0 66.66666 0 2 3 0 66.66666 -1.473 0.228 1 0043565 sequence-specific DNA binding F 6 17 23 35.29412 73.91304 6 17 23 35.29412 73.91304 -1.39 0.23 1 0033179 proton-transporting V-type ATPase, V0 domain C 0 2 2 0 100 0 2 2 0 100 -1.473 0.231 1 0008108 UDP-glucose:hexose-1-phosphate uridylyltransferase activity F 0 2 2 0 100 0 2 2 0 100 -1.473 0.231 1 0033176 proton-transporting V-type ATPase complex C 0 0 0 0 0 0 2 2 0 100 -1.473 0.231 1 0043648 dicarboxylic acid metabolic process P 0 0 0 0 0 8 11 19 72.72727 57.89474 1.382 0.232 1 0016628 oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor F 0 0 0 0 0 3 3 4 100 75 1.665 0.233 1 0018130 heterocycle biosynthetic process P 0 0 0 0 0 74 129 196 57.36434 65.81633 1.299 0.233 1 0009130 pyrimidine nucleoside monophosphate biosynthetic process P 0 0 0 0 0 5 6 12 83.33334 50 1.539 0.234 1 0016884 carbon-nitrogen ligase activity, with glutamine as amido-N-donor F 2 2 2 100 100 5 6 7 83.33334 85.71429 1.539 0.234 1 0009129 pyrimidine nucleoside monophosphate metabolic process P 0 0 0 0 0 5 6 12 83.33334 50 1.539 0.234 1 0050830 defense response to Gram-positive bacterium P 0 2 2 0 100 0 2 2 0 100 -1.473 0.234 1 0032553 ribonucleotide binding F 0 0 0 0 0 123 221 293 55.65611 75.42662 1.221 0.236 1 0008409 5’-3’ exonuclease activity F 3 3 3 100 100 3 3 3 100 100 1.665 0.237 1 0016837 carbon-oxygen lyase activity, acting on polysaccharides F 0 1 1 0 100 0 2 2 0 100 -1.473 0.238 1 0032549 ribonucleoside binding F 1 1 1 100 100 122 219 290 55.70776 75.51724 1.231 0.241 1 0001882 nucleoside binding F 0 0 0 0 0 122 219 290 55.70776 75.51724 1.231 0.241 1 0009144 purine nucleoside triphosphate metabolic process P 0 0 0 0 0 37 81 103 45.67901 78.64078 -1.187 0.241 1 0009205 purine ribonucleoside triphosphate metabolic process P 0 0 0 0 0 37 81 103 45.67901 78.64078 -1.187 0.241 1 0015934 large ribosomal subunit C 3 3 7 100 42.85714 3 3 7 100 42.85714 1.665 0.242 1 0008289 lipid binding F 2 2 2 100 100 3 3 3 100 100 1.665 0.243 1 0009435 NAD biosynthetic process P 3 3 4 100 75 3 3 4 100 75 1.665 0.244 1 0071822 protein complex subunit organization P 0 0 0 0 0 8 11 15 72.72727 73.33334 1.382 0.244 1 0061024 membrane organization P 0 0 0 0 0 3 3 4 100 75 1.665 0.245 1 0044802 single-organism membrane organization P 0 0 0 0 0 3 3 4 100 75 1.665 0.245 1 0005977 glycogen metabolic process P 0 1 2 0 50 0 2 4 0 50 -1.473 0.245 1 0009250 glucan biosynthetic process P 0 1 1 0 100 0 2 4 0 50 -1.473 0.245 1 0006073 cellular glucan metabolic process P 0 0 0 0 0 0 2 4 0 50 -1.473 0.245 1 0015370 solute:sodium symporter activity F 0 0 0 0 0 0 2 2 0 100 -1.473 0.245 1 0005978 glycogen biosynthetic process P 0 2 4 0 50 0 2 4 0 50 -1.473 0.245 1 0006112 energy reserve metabolic process P 0 0 0 0 0 0 2 4 0 50 -1.473 0.245 1 0015081 sodium ion transmembrane transporter activity F 0 0 0 0 0 0 2 2 0 100 -1.473 0.245 1 0044042 glucan metabolic process P 0 0 0 0 0 0 2 4 0 50 -1.473 0.245 1 0046417 chorismate metabolic process P 0 0 1 0 0 3 3 9 100 33.33333 1.665 0.246 1 0009423 chorismate biosynthetic process P 3 3 8 100 37.5 3 3 8 100 37.5 1.665 0.246 1 0006284 base-excision repair P 3 3 5 100 60 3 3 5 100 60 1.665 0.247 1 0044264 cellular polysaccharide metabolic process P 0 0 0 0 0 8 11 13 72.72727 84.61539 1.382 0.247 1 0033554 cellular response to stress P 0 0 0 0 0 17 26 37 65.38461 70.27027 1.382 0.248 1 0006094 gluconeogenesis P 3 3 4 100 75 3 3 4 100 75 1.665 0.249 1 0046364 monosaccharide biosynthetic process P 0 0 0 0 0 3 3 4 100 75 1.665 0.249 1 0019319 hexose biosynthetic process P 0 0 0 0 0 3 3 4 100 75 1.665 0.249 1 1901070 guanosine-containing compound biosynthetic process P 0 0 0 0 0 3 3 3 100 100 1.665 0.251 1 0008081 phosphoric diester hydrolase activity F 3 3 5 100 60 3 3 5 100 60 1.665 0.251 1 0016149 translation release factor activity, codon specific F 3 3 3 100 100 3 3 3 100 100 1.665 0.252 1 0008079 translation termination factor activity F 0 0 0 0 0 3 3 3 100 100 1.665 0.252 1 0003747 translation release factor activity F 2 2 2 100 100 3 3 3 100 100 1.665 0.252 1 0006996 organelle organization P 0 0 0 0 0 3 3 4 100 75 1.665 0.252 1 0003743 translation initiation factor activity F 3 3 3 100 100 3 3 3 100 100 1.665 0.253 1 0006413 translational initiation P 3 3 4 100 75 3 3 4 100 75 1.665 0.253 1 0008213 protein alkylation P 0 0 0 0 0 3 3 3 100 100 1.665 0.253 1 0008276 protein methyltransferase activity F 2 2 2 100 100 3 3 3 100 100 1.665 0.253 1 0006479 protein methylation P 2 2 2 100 100 3 3 3 100 100 1.665 0.253 1 0006813 potassium ion transport P 2 2 3 100 66.66666 3 3 4 100 75 1.665 0.255 1 0006027 glycosaminoglycan catabolic process P 0 0 0 0 0 0 2 3 0 66.66666 -1.473 0.256 1 0006026 aminoglycan catabolic process P 0 0 0 0 0 0 2 3 0 66.66666 -1.473 0.256 1 0009253 peptidoglycan catabolic process P 0 2 3 0 66.66666 0 2 3 0 66.66666 -1.473 0.256 1 0016657 oxidoreductase activity, acting on NAD(P)H, nitrogenous group as acceptor F 0 0 0 0 0 0 2 2 0 100 -1.473 0.256 1 0006047 UDP-N-acetylglucosamine metabolic process P 2 2 2 100 100 3 3 3 100 100 1.665 0.258 1 0055085 transmembrane transport P 13 32 38 40.625 84.21053 22 50 67 44 74.62687 -1.162 0.262 1 0009142 nucleoside triphosphate biosynthetic process P 0 0 0 0 0 9 13 17 69.23077 76.47059 1.25 0.263 1 0006417 regulation of translation P 2 2 2 100 100 6 8 10 75 80 1.306 0.264 1 0032268 regulation of cellular protein metabolic process P 0 0 0 0 0 6 8 10 75 80 1.306 0.264 1 0051246 regulation of protein metabolic process P 0 0 0 0 0 6 8 10 75 80 1.306 0.264 1 0017111 nucleoside-triphosphatase activity F 31 76 91 40.78947 83.51649 53 113 146 46.90266 77.39726 -1.151 0.266 1 0009218 pyrimidine ribonucleotide metabolic process P 0 0 0 0 0 6 8 14 75 57.14286 1.306 0.267 1 0009220 pyrimidine ribonucleotide biosynthetic process P 0 0 0 0 0 6 8 14 75 57.14286 1.306 0.267 1 0046132 pyrimidine ribonucleoside biosynthetic process P 0 0 0 0 0 6 8 14 75 57.14286 1.306 0.267 1 0046134 pyrimidine nucleoside biosynthetic process P 0 0 0 0 0 6 8 14 75 57.14286 1.306 0.267 1 0000160 phosphorelay signal transduction system P 8 21 27 38.09524 77.77778 8 21 27 38.09524 77.77778 -1.289 0.267 1 0051188 cofactor biosynthetic process P 0 0 0 0 0 19 30 35 63.33333 85.71429 1.259 0.268 1 0015074 DNA integration P 2 7 8 28.57143 87.5 2 7 8 28.57143 87.5 -1.245 0.268 1 0005996 monosaccharide metabolic process P 0 1 2 0 50 13 20 30 65 66.66666 1.173 0.27 1 0019318 hexose metabolic process P 0 0 1 0 0 13 20 29 65 68.96552 1.173 0.27 1 0016818 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides F 1 1 1 100 100 54 115 150 46.95652 76.66666 -1.15 0.273 1 0016462 pyrophosphatase activity F 1 1 2 100 50 54 115 150 46.95652 76.66666 -1.15 0.273 1 0001883 purine nucleoside binding F 0 0 0 0 0 121 218 289 55.50459 75.43253 1.16 0.274 1 0035639 purine ribonucleoside triphosphate binding F 0 0 0 0 0 121 218 289 55.50459 75.43253 1.16 0.274 1 0032555 purine ribonucleotide binding F 0 0 0 0 0 121 218 289 55.50459 75.43253 1.16 0.274 1 0032550 purine ribonucleoside binding F 0 0 0 0 0 121 218 289 55.50459 75.43253 1.16 0.274 1 0016725 oxidoreductase activity, acting on CH or CH2 groups F 0 0 0 0 0 3 3 4 100 75 1.665 0.275 1 0009081 branched-chain amino acid metabolic process P 0 1 1 0 100 2 7 10 28.57143 70 -1.245 0.275 1 0009082 branched-chain amino acid biosynthetic process P 2 5 8 40 62.5 2 7 10 28.57143 70 -1.245 0.275 1 0016787 hydrolase activity F 60 121 183 49.58678 66.12022 126 257 352 49.02724 73.01136 -1.102 0.28 1 0046961 proton-transporting ATPase activity, rotational mechanism F 3 3 3 100 100 3 3 3 100 100 1.665 0.282 1 0036442 hydrogen-exporting ATPase activity F 0 0 0 0 0 3 3 3 100 100 1.665 0.282 1 0016747 transferase activity, transferring acyl groups other than amino-acyl groups F 5 5 6 100 83.33334 20 32 42 62.5 76.19048 1.206 0.284 1 0051536 iron-sulfur cluster binding F 5 7 9 71.42857 77.77778 6 8 11 75 72.72727 1.306 0.286 1 0051540 metal cluster binding F 0 0 0 0 0 6 8 11 75 72.72727 1.306 0.286 1 0016763 transferase activity, transferring pentosyl groups F 3 4 7 75 57.14286 6 8 16 75 50 1.306 0.289 1 0046390 ribose phosphate biosynthetic process P 0 0 0 0 0 20 32 49 62.5 65.30612 1.206 0.291 1 0009073 aromatic amino acid family biosynthetic process P 5 6 13 83.33334 46.15385 6 8 16 75 50 1.306 0.292 1 0009072 aromatic amino acid family metabolic process P 0 0 0 0 0 6 8 16 75 50 1.306 0.292 1 0006790 sulfur compound metabolic process P 0 0 0 0 0 5 14 22 35.71429 63.63636 -1.228 0.292 1 0009152 purine ribonucleotide biosynthetic process P 1 1 1 100 100 15 24 33 62.5 72.72727 1.04 0.295 1 0051641 cellular localization P 0 0 0 0 0 6 8 11 75 72.72727 1.306 0.296 1 0003677 DNA binding F 55 120 175 45.83333 68.57143 58 123 178 47.15447 69.10112 -1.147 0.298 1 0009199 ribonucleoside triphosphate metabolic process P 0 0 0 0 0 39 84 106 46.42857 79.24529 -1.068 0.311 1 0042254 ribosome biogenesis P 3 5 8 60 62.5 11 17 21 64.70588 80.95238 1.056 0.321 1 0022613 ribonucleoprotein complex biogenesis P 0 0 0 0 0 11 17 21 64.70588 80.95238 1.056 0.321 1 0009124 nucleoside monophosphate biosynthetic process P 0 0 0 0 0 15 24 40 62.5 60 1.04 0.321 1 0006281 DNA repair P 16 24 34 66.66666 70.58823 16 25 36 64 69.44444 1.214 0.322 1 0006974 cellular response to DNA damage stimulus P 10 17 24 58.82353 70.83334 16 25 36 64 69.44444 1.214 0.322 1 0016301 kinase activity F 22 47 69 46.80851 68.11594 24 53 77 45.28302 68.83117 -1.006 0.326 1 0009451 RNA modification P 3 6 8 50 75 18 29 35 62.06897 82.85714 1.099 0.328 1 0016817 hydrolase activity, acting on acid anhydrides F 2 2 2 100 100 55 116 151 47.41379 76.82119 -1.051 0.329 1 0071944 cell periphery C 0 0 0 0 0 55 116 165 47.41379 70.30303 -1.051 0.331 1 0006220 pyrimidine nucleotide metabolic process P 0 0 1 0 0 7 10 18 70 55.55556 1.144 0.333 1 0006213 pyrimidine nucleoside metabolic process P 0 1 1 0 100 7 10 16 70 62.5 1.144 0.336 1 0015075 ion transmembrane transporter activity F 0 0 0 0 0 24 53 69 45.28302 76.81159 -1.006 0.34 1 0090304 nucleic acid metabolic process P 0 0 0 0 0 109 198 267 55.05051 74.1573 0.95 0.344 1 0005886 plasma membrane C 49 100 146 49 68.49315 49 103 149 47.57281 69.12752 -0.949 0.347 1 0016866 intramolecular transferase activity F 1 3 3 33.33333 100 7 10 16 70 62.5 1.144 0.35 1 0046983 protein dimerization activity F 1 4 6 25 66.66666 1 4 8 25 50 -1.083 0.35 1 0015297 antiporter activity F 1 3 3 33.33333 100 1 4 4 25 100 -1.083 0.35 1 0015925 galactosidase activity F 0 0 0 0 0 1 4 5 25 80 -1.083 0.351 1 0019829 cation-transporting ATPase activity F 2 2 4 100 50 7 10 15 70 66.66666 1.144 0.354 1 0046700 heterocycle catabolic process P 0 0 0 0 0 38 81 104 46.91358 77.88461 -0.956 0.354 1 0044270 cellular nitrogen compound catabolic process P 0 0 0 0 0 38 81 104 46.91358 77.88461 -0.956 0.354 1 0019439 aromatic compound catabolic process P 0 0 0 0 0 38 81 104 46.91358 77.88461 -0.956 0.354 1 1901361 organic cyclic compound catabolic process P 0 0 0 0 0 38 81 104 46.91358 77.88461 -0.956 0.354 1 0034655 nucleobase-containing compound catabolic process P 0 0 0 0 0 38 81 104 46.91358 77.88461 -0.956 0.354 1 0042597 periplasmic space C 0 3 3 0 100 1 4 5 25 80 -1.083 0.356 1 0015698 inorganic anion transport P 1 1 2 100 50 7 10 15 70 66.66666 1.144 0.358 1 0003899 DNA-directed RNA polymerase activity F 4 4 6 100 66.66666 4 5 7 80 71.42857 1.255 0.36 1 0034062 RNA polymerase activity F 0 0 0 0 0 4 5 7 80 71.42857 1.255 0.36 1 0015711 organic anion transport P 0 0 0 0 0 1 4 7 25 57.14286 -1.083 0.36 1 0046942 carboxylic acid transport P 0 0 0 0 0 1 4 6 25 66.66666 -1.083 0.36 1 0015849 organic acid transport P 0 0 0 0 0 1 4 6 25 66.66666 -1.083 0.36 1 0019238 cyclohydrolase activity F 0 0 0 0 0 1 4 5 25 80 -1.083 0.36 1 0009890 negative regulation of biosynthetic process P 0 0 0 0 0 4 5 8 80 62.5 1.255 0.363 1 2000113 negative regulation of cellular macromolecule biosynthetic process P 0 0 0 0 0 4 5 8 80 62.5 1.255 0.363 1 0048523 negative regulation of cellular process P 0 0 0 0 0 4 5 10 80 50 1.255 0.363 1 0031327 negative regulation of cellular biosynthetic process P 0 0 0 0 0 4 5 8 80 62.5 1.255 0.363 1 0010605 negative regulation of macromolecule metabolic process P 0 0 0 0 0 4 5 8 80 62.5 1.255 0.363 1 0031324 negative regulation of cellular metabolic process P 0 0 0 0 0 4 5 10 80 50 1.255 0.363 1 0010558 negative regulation of macromolecule biosynthetic process P 0 0 0 0 0 4 5 8 80 62.5 1.255 0.363 1 0009892 negative regulation of metabolic process P 0 0 0 0 0 4 5 10 80 50 1.255 0.363 1 0048519 negative regulation of biological process P 0 0 0 0 0 4 5 10 80 50 1.255 0.363 1 0033218 amide binding F 0 0 0 0 0 4 5 6 80 83.33334 1.255 0.364 1 0008658 penicillin binding F 4 5 6 80 83.33334 4 5 6 80 83.33334 1.255 0.364 1 0033293 monocarboxylic acid binding F 0 0 0 0 0 4 5 6 80 83.33334 1.255 0.364 1 0008144 drug binding F 0 0 0 0 0 4 5 6 80 83.33334 1.255 0.364 1 0004520 endodeoxyribonuclease activity F 0 0 0 0 0 1 4 6 25 66.66666 -1.083 0.364 1 0034654 nucleobase-containing compound biosynthetic process P 0 0 0 0 0 59 104 159 56.73077 65.40881 1.015 0.368 1 0019637 organophosphate metabolic process P 0 0 0 0 0 84 151 201 55.62914 75.12437 0.962 0.368 1 0019400 alditol metabolic process P 0 0 0 0 0 1 4 6 25 66.66666 -1.083 0.369 1 0016820 hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances F 4 9 9 44.44444 100 13 30 39 43.33333 76.92308 -0.965 0.371 1 0006222 UMP biosynthetic process P 1 1 2 100 50 4 5 11 80 45.45454 1.255 0.376 1 0046049 UMP metabolic process P 0 0 0 0 0 4 5 11 80 45.45454 1.255 0.376 1 0009173 pyrimidine ribonucleoside monophosphate metabolic process P 0 0 0 0 0 4 5 11 80 45.45454 1.255 0.376 1 0009174 pyrimidine ribonucleoside monophosphate biosynthetic process P 0 0 0 0 0 4 5 11 80 45.45454 1.255 0.376 1 0006306 DNA methylation P 1 4 6 25 66.66666 1 4 6 25 66.66666 -1.083 0.378 1 0040029 regulation of gene expression, epigenetic P 0 0 0 0 0 1 4 6 25 66.66666 -1.083 0.378 1 0006305 DNA alkylation P 0 0 0 0 0 1 4 6 25 66.66666 -1.083 0.378 1 0044728 DNA methylation or demethylation P 0 0 0 0 0 1 4 6 25 66.66666 -1.083 0.378 1 0000287 magnesium ion binding F 18 29 40 62.06897 72.5 18 29 40 62.06897 72.5 1.099 0.381 1 0009141 nucleoside triphosphate metabolic process P 0 0 0 0 0 41 87 110 47.12644 79.09091 -0.952 0.381 1 0004177 aminopeptidase activity F 4 5 8 80 62.5 4 5 8 80 62.5 1.255 0.382 1 0016491 oxidoreductase activity F 34 63 84 53.96825 75 40 70 92 57.14286 76.08696 0.889 0.382 1 0006040 amino sugar metabolic process P 0 0 0 0 0 4 5 10 80 50 1.255 0.387 1 0015103 inorganic anion transmembrane transporter activity F 1 1 2 100 50 4 5 7 80 71.42857 1.255 0.388 1 0009148 pyrimidine nucleoside triphosphate biosynthetic process P 0 0 0 0 0 4 5 6 80 83.33334 1.255 0.389 1 0042625 ATPase activity, coupled to transmembrane movement of ions F 0 0 0 0 0 8 12 18 66.66666 66.66666 1.022 0.39 1 0016740 transferase activity F 90 181 263 49.72376 68.82129 110 223 318 49.32735 70.12579 -0.904 0.391 1 0060089 molecular transducer activity F 0 0 0 0 0 9 22 28 40.90909 78.57143 -1.053 0.391 1 0004871 signal transducer activity F 1 6 9 16.66667 66.66666 9 22 28 40.90909 78.57143 -1.053 0.391 1 0004521 endoribonuclease activity F 1 1 2 100 50 4 5 9 80 55.55556 1.255 0.392 1 0019205 nucleobase-containing compound kinase activity F 0 1 1 0 100 4 5 8 80 62.5 1.255 0.394 1 0009117 nucleotide metabolic process P 2 2 3 100 66.66666 71 127 171 55.90551 74.269 0.937 0.394 1 0006753 nucleoside phosphate metabolic process P 0 0 0 0 0 71 127 171 55.90551 74.269 0.937 0.394 1 0008175 tRNA methyltransferase activity F 0 1 1 0 100 4 5 6 80 83.33334 1.255 0.395 1 0008757 S-adenosylmethionine-dependent methyltransferase activity F 1 2 2 50 100 8 12 15 66.66666 80 1.022 0.396 1 0016310 phosphorylation P 23 48 70 47.91667 68.57143 24 52 76 46.15385 68.42105 -0.867 0.399 1 0044272 sulfur compound biosynthetic process P 0 0 0 0 0 5 13 19 38.46154 68.42105 -0.984 0.401 1 0009201 ribonucleoside triphosphate biosynthetic process P 0 0 0 0 0 8 12 15 66.66666 80 1.022 0.403 1 0009311 oligosaccharide metabolic process P 0 0 0 0 0 2 6 11 33.33333 54.54546 -0.918 0.409 1 0016746 transferase activity, transferring acyl groups F 7 11 14 63.63636 78.57143 21 35 47 60 74.46809 0.962 0.411 1 0072522 purine-containing compound biosynthetic process P 0 0 0 0 0 16 26 35 61.53846 74.28571 0.984 0.414 1 1901607 alpha-amino acid biosynthetic process P 0 0 0 0 0 22 37 55 59.45946 67.27273 0.923 0.417 1 0004386 helicase activity F 5 13 19 38.46154 68.42105 5 13 19 38.46154 68.42105 -0.984 0.421 1 0009156 ribonucleoside monophosphate biosynthetic process P 0 1 2 0 50 14 23 39 60.86956 58.97436 0.859 0.422 1 0042724 thiamine-containing compound biosynthetic process P 0 0 0 0 0 2 6 8 33.33333 75 -0.918 0.422 1 0009228 thiamine biosynthetic process P 2 6 8 33.33333 75 2 6 8 33.33333 75 -0.918 0.422 1 0016830 carbon-carbon lyase activity F 0 0 0 0 0 6 15 22 40 68.18182 -0.937 0.423 1 0022610 biological adhesion P 0 0 0 0 0 2 6 7 33.33333 85.71429 -0.918 0.424 1 1901615 organic hydroxy compound metabolic process P 0 0 0 0 0 2 6 9 33.33333 66.66666 -0.918 0.424 1 0006066 alcohol metabolic process P 0 1 1 0 100 2 6 8 33.33333 75 -0.918 0.424 1 0007155 cell adhesion P 2 6 7 33.33333 85.71429 2 6 7 33.33333 85.71429 -0.918 0.424 1 0050660 flavin adenine dinucleotide binding F 8 12 13 66.66666 92.30769 8 12 13 66.66666 92.30769 1.022 0.425 1 1901575 organic substance catabolic process P 0 0 0 0 0 51 106 142 48.11321 74.64789 -0.847 0.426 1 0009056 catabolic process P 0 0 0 0 0 51 106 144 48.11321 73.61111 -0.847 0.426 1 0051252 regulation of RNA metabolic process P 0 0 0 0 0 26 56 86 46.42857 65.11628 -0.859 0.43 1 2001141 regulation of RNA biosynthetic process P 0 0 0 0 0 26 56 86 46.42857 65.11628 -0.859 0.43 1 0006355 regulation of transcription, DNA-dependent P 26 55 84 47.27273 65.47619 26 56 86 46.42857 65.11628 -0.859 0.43 1 0009605 response to external stimulus P 0 0 0 0 0 6 15 17 40 88.23529 -0.937 0.43 1 0009991 response to extracellular stimulus P 0 0 0 0 0 6 15 17 40 88.23529 -0.937 0.43 1 0071496 cellular response to external stimulus P 0 0 0 0 0 6 15 17 40 88.23529 -0.937 0.43 1 0031668 cellular response to extracellular stimulus P 0 0 0 0 0 6 15 17 40 88.23529 -0.937 0.43 1 0019219 regulation of nucleobase-containing compound metabolic process P 0 0 0 0 0 27 58 88 46.55172 65.90909 -0.856 0.434 1 0051171 regulation of nitrogen compound metabolic process P 0 0 0 0 0 27 58 88 46.55172 65.90909 -0.856 0.434 1 0004084 branched-chain-amino-acid transaminase activity F 0 1 1 0 100 0 1 1 0 100 -1.041 0.437 1 0052656 L-isoleucine transaminase activity F 0 1 1 0 100 0 1 1 0 100 -1.041 0.437 1 0052655 L-valine transaminase activity F 0 1 1 0 100 0 1 1 0 100 -1.041 0.437 1 0052654 L-leucine transaminase activity F 0 1 1 0 100 0 1 1 0 100 -1.041 0.437 1 0006414 translational elongation P 2 2 6 100 33.33333 5 7 12 71.42857 58.33333 1.031 0.442 1 0072528 pyrimidine-containing compound biosynthetic process P 0 0 0 0 0 10 16 26 62.5 61.53846 0.846 0.442 1 0042592 homeostatic process P 0 0 0 0 0 5 7 13 71.42857 53.84615 1.031 0.445 1 0019725 cellular homeostasis P 0 0 0 0 0 5 7 11 71.42857 63.63636 1.031 0.445 1 0009379 Holliday junction helicase complex C 0 1 1 0 100 0 1 1 0 100 -1.041 0.446 1 0048476 Holliday junction resolvase complex C 0 0 0 0 0 0 1 1 0 100 -1.041 0.446 1 0004794 L-threonine ammonia-lyase activity F 0 1 1 0 100 0 1 1 0 100 -1.041 0.446 1 0033202 DNA helicase complex C 0 0 0 0 0 0 1 1 0 100 -1.041 0.446 1 0009378 four-way junction helicase activity F 0 1 2 0 50 0 1 2 0 50 -1.041 0.446 1 0004417 hydroxyethylthiazole kinase activity F 0 1 2 0 50 0 1 2 0 50 -1.041 0.449 1 0006428 isoleucyl-tRNA aminoacylation P 0 1 1 0 100 0 1 1 0 100 -1.041 0.449 1 0004822 isoleucine-tRNA ligase activity F 0 1 1 0 100 0 1 1 0 100 -1.041 0.449 1 1901605 alpha-amino acid metabolic process P 0 0 0 0 0 25 43 65 58.13953 66.15385 0.821 0.451 1 0006163 purine nucleotide metabolic process P 1 2 3 50 66.66666 49 101 131 48.51485 77.09924 -0.74 0.451 1 0070727 cellular macromolecule localization P 0 0 0 0 0 5 7 9 71.42857 77.77778 1.031 0.452 1 0034613 cellular protein localization P 0 0 0 0 0 5 7 9 71.42857 77.77778 1.031 0.452 1 0009226 nucleotide-sugar biosynthetic process P 0 0 0 0 0 2 2 4 100 50 1.359 0.453 1 0046349 amino sugar biosynthetic process P 0 0 0 0 0 2 2 4 100 50 1.359 0.453 1 0032261 purine nucleotide salvage P 0 0 0 0 0 0 1 4 0 25 -1.041 0.454 1 0044209 AMP salvage P 0 1 2 0 50 0 1 2 0 50 -1.041 0.454 1 0043101 purine-containing compound salvage P 0 0 1 0 0 0 1 4 0 25 -1.041 0.454 1 0004017 adenylate kinase activity F 0 1 1 0 100 0 1 1 0 100 -1.041 0.454 1 0006811 ion transport P 8 12 15 66.66666 80 24 41 55 58.53659 74.54546 0.853 0.455 1 0050110 mucinaminylserine mucinaminidase activity F 0 1 1 0 100 0 1 1 0 100 -1.041 0.455 1 0033926 glycopeptide alpha-N-acetylgalactosaminidase activity F 0 1 1 0 100 0 1 1 0 100 -1.041 0.455 1 0004148 dihydrolipoyl dehydrogenase activity F 0 1 1 0 100 0 1 1 0 100 -1.041 0.455 1 1901682 sulfur compound transmembrane transporter activity F 0 0 0 0 0 0 1 1 0 100 -1.041 0.457 1 0000099 sulfur amino acid transmembrane transporter activity F 0 0 0 0 0 0 1 1 0 100 -1.041 0.457 1 0000101 sulfur amino acid transport P 0 0 0 0 0 0 1 1 0 100 -1.041 0.457 1 0043865 methionine transmembrane transporter activity F 0 1 1 0 100 0 1 1 0 100 -1.041 0.457 1 0015821 methionine transport P 0 1 1 0 100 0 1 1 0 100 -1.041 0.457 1 0051649 establishment of localization in cell P 0 0 0 0 0 5 7 9 71.42857 77.77778 1.031 0.458 1 0008170 N-methyltransferase activity F 0 2 4 0 50 2 6 8 33.33333 75 -0.918 0.458 1 0071265 L-methionine biosynthetic process P 0 0 0 0 0 0 1 3 0 33.33333 -1.041 0.458 1 0006566 threonine metabolic process P 0 0 1 0 0 0 1 4 0 25 -1.041 0.458 1 0042274 ribosomal small subunit biogenesis P 0 1 2 0 50 0 1 2 0 50 -1.041 0.458 1 0003942 N-acetyl-gamma-glutamyl-phosphate reductase activity F 0 1 1 0 100 0 1 1 0 100 -1.041 0.458 1 0071266 ’de novo’ L-methionine biosynthetic process P 0 1 1 0 100 0 1 2 0 50 -1.041 0.458 1 0009088 threonine biosynthetic process P 0 1 4 0 25 0 1 4 0 25 -1.041 0.458 1 0004073 aspartate-semialdehyde dehydrogenase activity F 0 1 1 0 100 0 1 1 0 100 -1.041 0.458 1 0043021 ribonucleoprotein complex binding F 0 0 0 0 0 0 1 2 0 50 -1.041 0.458 1 0043022 ribosome binding F 0 1 2 0 50 0 1 2 0 50 -1.041 0.458 1 0019478 D-amino acid catabolic process P 0 1 1 0 100 0 1 1 0 100 -1.041 0.459 1 0004308 exo-alpha-sialidase activity F 0 1 2 0 50 0 1 2 0 50 -1.041 0.46 1 0005363 maltose transmembrane transporter activity F 0 1 1 0 100 0 1 1 0 100 -1.041 0.46 1 0016997 alpha-sialidase activity F 0 0 0 0 0 0 1 2 0 50 -1.041 0.46 1 0015768 maltose transport P 0 1 1 0 100 0 1 1 0 100 -1.041 0.46 1 0052794 exo-alpha-(2->3)-sialidase activity F 0 1 2 0 50 0 1 2 0 50 -1.041 0.46 1 0052795 exo-alpha-(2->6)-sialidase activity F 0 1 2 0 50 0 1 2 0 50 -1.041 0.46 1 0052796 exo-alpha-(2->8)-sialidase activity F 0 1 2 0 50 0 1 2 0 50 -1.041 0.46 1 0004055 argininosuccinate synthase activity F 0 1 1 0 100 0 1 1 0 100 -1.041 0.46 1 0008776 acetate kinase activity F 0 1 1 0 100 0 1 1 0 100 -1.041 0.46 1 0004739 pyruvate dehydrogenase (acetyl-transferring) activity F 0 1 1 0 100 0 1 1 0 100 -1.041 0.46 1 0004738 pyruvate dehydrogenase activity F 0 0 0 0 0 0 1 1 0 100 -1.041 0.46 1 0006090 pyruvate metabolic process P 0 0 0 0 0 0 1 2 0 50 -1.041 0.46 1 0006086 acetyl-CoA biosynthetic process from pyruvate P 0 1 1 0 100 0 1 1 0 100 -1.041 0.46 1 0033925 mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase activity F 0 1 2 0 50 0 1 2 0 50 -1.041 0.461 1 0008737 L-fuculokinase activity F 0 1 1 0 100 0 1 1 0 100 -1.041 0.462 1 0050334 thiaminase activity F 0 1 1 0 100 0 1 1 0 100 -1.041 0.462 1 1901681 sulfur compound binding F 0 0 0 0 0 5 7 8 71.42857 87.5 1.031 0.463 1 0046080 dUTP metabolic process P 0 1 1 0 100 0 1 1 0 100 -1.041 0.463 1 0004742 dihydrolipoyllysine-residue acetyltransferase activity F 0 1 1 0 100 0 1 1 0 100 -1.041 0.464 1 0016418 S-acetyltransferase activity F 0 0 0 0 0 0 1 1 0 100 -1.041 0.464 1 0030523 dihydrolipoamide S-acyltransferase activity F 0 0 0 0 0 0 1 1 0 100 -1.041 0.464 1 0003937 IMP cyclohydrolase activity F 0 1 1 0 100 0 1 1 0 100 -1.041 0.465 1 0016742 hydroxymethyl-, formyl- and related transferase activity F 0 0 2 0 0 0 1 4 0 25 -1.041 0.465 1 0004643 phosphoribosylaminoimidazolecarboxamide formyltransferase activity F 0 1 1 0 100 0 1 1 0 100 -1.041 0.465 1 0008113 peptide-methionine (S)-S-oxide reductase activity F 0 1 2 0 50 0 1 2 0 50 -1.041 0.465 1 0016671 oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor F 0 0 0 0 0 0 1 2 0 50 -1.041 0.465 1 0033743 peptide-methionine (R)-S-oxide reductase activity F 0 1 2 0 50 0 1 2 0 50 -1.041 0.465 1 0008299 isoprenoid biosynthetic process P 2 2 6 100 33.33333 2 2 6 100 33.33333 1.359 0.466 1 0006720 isoprenoid metabolic process P 0 0 0 0 0 2 2 6 100 33.33333 1.359 0.466 1 0004735 pyrroline-5-carboxylate reductase activity F 0 1 1 0 100 0 1 1 0 100 -1.041 0.466 1 0009404 toxin metabolic process P 0 0 0 0 0 2 2 2 100 100 1.359 0.467 1 0044550 secondary metabolite biosynthetic process P 0 0 0 0 0 2 2 2 100 100 1.359 0.467 1 0019748 secondary metabolic process P 0 0 0 0 0 2 2 2 100 100 1.359 0.467 1 0009403 toxin biosynthetic process P 1 1 1 100 100 2 2 2 100 100 1.359 0.467 1 0019240 citrulline biosynthetic process P 0 0 0 0 0 0 1 1 0 100 -1.041 0.467 1 0043213 bacteriocin transport P 0 1 1 0 100 0 1 1 0 100 -1.041 0.467 1 0022885 bacteriocin transmembrane transporter activity F 0 1 1 0 100 0 1 1 0 100 -1.041 0.467 1 0019547 arginine catabolic process to ornithine P 0 1 2 0 50 0 1 2 0 50 -1.041 0.467 1 0018101 protein citrullination P 0 1 1 0 100 0 1 1 0 100 -1.041 0.467 1 0016990 arginine deiminase activity F 0 1 1 0 100 0 1 1 0 100 -1.041 0.467 1 0030340 hyaluronate lyase activity F 0 1 1 0 100 0 1 1 0 100 -1.041 0.467 1 0008865 fructokinase activity F 0 1 1 0 100 0 1 1 0 100 -1.041 0.467 1 0006527 arginine catabolic process P 0 1 1 0 100 0 1 2 0 50 -1.041 0.467 1 0000052 citrulline metabolic process P 0 0 0 0 0 0 1 1 0 100 -1.041 0.467 1 0018195 peptidyl-arginine modification P 0 0 0 0 0 0 1 1 0 100 -1.041 0.467 1 0042887 amide transmembrane transporter activity F 0 0 0 0 0 0 1 1 0 100 -1.041 0.467 1 0006591 ornithine metabolic process P 0 0 1 0 0 0 1 2 0 50 -1.041 0.467 1 0006353 DNA-dependent transcription, termination P 2 2 3 100 66.66666 2 2 4 100 50 1.359 0.468 1 0050044 galactose-6-phosphate isomerase activity F 0 1 2 0 50 0 1 2 0 50 -1.041 0.468 1 0019388 galactose catabolic process P 0 1 2 0 50 0 1 2 0 50 -1.041 0.468 1 0007166 cell surface receptor signaling pathway P 0 0 0 0 0 0 1 1 0 100 -1.041 0.469 1 0007186 G-protein coupled receptor signaling pathway P 0 0 0 0 0 0 1 1 0 100 -1.041 0.469 1 0007205 protein kinase C-activating G-protein coupled receptor signaling pathway P 0 1 1 0 100 0 1 1 0 100 -1.041 0.469 1 0033739 preQ1 synthase activity F 0 1 1 0 100 0 1 1 0 100 -1.041 0.47 1 0016661 oxidoreductase activity, acting on other nitrogenous compounds as donors F 0 0 0 0 0 0 1 1 0 100 -1.041 0.47 1 0046857 oxidoreductase activity, acting on other nitrogenous compounds as donors, with NAD or NADP as acceptor F 0 1 1 0 100 0 1 1 0 100 -1.041 0.47 1 0008379 thioredoxin peroxidase activity F 0 1 1 0 100 0 1 1 0 100 -1.041 0.47 1 0016154 pyrimidine-nucleoside phosphorylase activity F 0 1 1 0 100 0 1 1 0 100 -1.041 0.47 1 0016880 acid-ammonia (or amide) ligase activity F 0 0 0 0 0 2 2 3 100 66.66666 1.359 0.471 1 0008242 omega peptidase activity F 0 0 0 0 0 0 1 2 0 50 -1.041 0.472 1 0016920 pyroglutamyl-peptidase activity F 0 1 2 0 50 0 1 2 0 50 -1.041 0.472 1 0004349 glutamate 5-kinase activity F 0 1 1 0 100 0 1 1 0 100 -1.041 0.473 1 0019202 amino acid kinase activity F 0 0 0 0 0 0 1 3 0 33.33333 -1.041 0.473 1 0006772 thiamine metabolic process P 1 2 2 50 100 3 8 10 37.5 80 -0.824 0.474 1 0042723 thiamine-containing compound metabolic process P 0 0 0 0 0 3 8 10 37.5 80 -0.824 0.474 1 0008926 mannitol-1-phosphate 5-dehydrogenase activity F 0 1 1 0 100 0 1 1 0 100 -1.041 0.474 1 0009316 3-isopropylmalate dehydratase complex C 0 1 1 0 100 0 1 1 0 100 -1.041 0.474 1 0015932 nucleobase-containing compound transmembrane transporter activity F 0 0 0 0 0 0 1 2 0 50 -1.041 0.474 1 0016434 rRNA (cytosine) methyltransferase activity F 0 0 0 0 0 0 1 1 0 100 -1.041 0.474 1 0008738 L-fuculose-phosphate aldolase activity F 0 1 1 0 100 0 1 1 0 100 -1.041 0.474 1 0008988 rRNA (adenine-N6-)-methyltransferase activity F 0 0 0 0 0 0 1 1 0 100 -1.041 0.474 1 0071424 rRNA (cytosine-N4-)-methyltransferase activity F 0 1 1 0 100 0 1 1 0 100 -1.041 0.474 1 0019594 mannitol metabolic process P 0 1 1 0 100 0 1 1 0 100 -1.041 0.474 1 0034257 nicotinamide riboside transmembrane transporter activity F 0 1 2 0 50 0 1 2 0 50 -1.041 0.474 1 0005337 nucleoside transmembrane transporter activity F 0 0 0 0 0 0 1 2 0 50 -1.041 0.474 1 0015931 nucleobase-containing compound transport P 0 0 0 0 0 0 1 2 0 50 -1.041 0.474 1 0090116 C-5 methylation of cytosine P 0 1 1 0 100 0 1 1 0 100 -1.041 0.474 1 0015858 nucleoside transport P 0 0 0 0 0 0 1 2 0 50 -1.041 0.474 1 0034258 nicotinamide riboside transport P 0 1 2 0 50 0 1 2 0 50 -1.041 0.474 1 0006059 hexitol metabolic process P 0 0 0 0 0 0 1 1 0 100 -1.041 0.474 1 0009008 DNA-methyltransferase activity F 0 0 0 0 0 0 1 3 0 33.33333 -1.041 0.474 1 0000179 rRNA (adenine-N6,N6-)-dimethyltransferase activity F 0 1 1 0 100 0 1 1 0 100 -1.041 0.474 1 0003886 DNA (cytosine-5-)-methyltransferase activity F 0 1 1 0 100 0 1 1 0 100 -1.041 0.474 1 1901505 carbohydrate derivative transporter activity F 0 0 0 0 0 0 1 2 0 50 -1.041 0.474 1 0052908 16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity F 0 1 1 0 100 0 1 1 0 100 -1.041 0.474 1 1901264 carbohydrate derivative transport P 0 0 0 0 0 0 1 2 0 50 -1.041 0.474 1 0032776 DNA methylation on cytosine P 0 0 0 0 0 0 1 1 0 100 -1.041 0.474 1 0003861 3-isopropylmalate dehydratase activity F 0 1 1 0 100 0 1 1 0 100 -1.041 0.474 1 0070526 threonylcarbamoyladenosine biosynthetic process P 2 2 3 100 66.66666 2 2 3 100 66.66666 1.359 0.475 1 0046085 adenosine metabolic process P 0 0 0 0 0 2 2 3 100 66.66666 1.359 0.475 1 0070525 threonylcarbamoyladenosine metabolic process P 0 0 0 0 0 2 2 3 100 66.66666 1.359 0.475 1 0033865 nucleoside bisphosphate metabolic process P 0 0 0 0 0 5 7 8 71.42857 87.5 1.031 0.475 1 0033875 ribonucleoside bisphosphate metabolic process P 0 0 0 0 0 5 7 8 71.42857 87.5 1.031 0.475 1 0034032 purine nucleoside bisphosphate metabolic process P 0 0 0 0 0 5 7 8 71.42857 87.5 1.031 0.475 1 0004477 methenyltetrahydrofolate cyclohydrolase activity F 0 1 1 0 100 0 1 1 0 100 -1.041 0.475 1 0042168 heme metabolic process P 0 0 0 0 0 0 1 1 0 100 -1.041 0.475 1 0006547 histidine metabolic process P 0 0 0 0 0 0 1 1 0 100 -1.041 0.475 1 0002097 tRNA wobble base modification P 0 0 0 0 0 0 1 1 0 100 -1.041 0.475 1 0002098 tRNA wobble uridine modification P 0 1 1 0 100 0 1 1 0 100 -1.041 0.475 1 0004488 methylenetetrahydrofolate dehydrogenase (NADP+) activity F 0 1 1 0 100 0 1 1 0 100 -1.041 0.475 1 0004325 ferrochelatase activity F 0 1 1 0 100 0 1 1 0 100 -1.041 0.475 1 0006783 heme biosynthetic process P 0 1 1 0 100 0 1 1 0 100 -1.041 0.475 1 0052803 imidazole-containing compound metabolic process P 0 0 0 0 0 0 1 1 0 100 -1.041 0.475 1 0004557 alpha-galactosidase activity F 0 1 1 0 100 0 1 1 0 100 -1.041 0.475 1 0052692 raffinose alpha-galactosidase activity F 0 1 1 0 100 0 1 1 0 100 -1.041 0.475 1 0000105 histidine biosynthetic process P 0 1 1 0 100 0 1 1 0 100 -1.041 0.475 1 0016423 tRNA (guanine) methyltransferase activity F 0 0 0 0 0 2 2 2 100 100 1.359 0.477 1 0004540 ribonuclease activity F 0 1 1 0 100 5 7 11 71.42857 63.63636 1.031 0.477 1 0004045 aminoacyl-tRNA hydrolase activity F 0 1 1 0 100 0 1 1 0 100 -1.041 0.477 1 0008888 glycerol dehydrogenase [NAD+] activity F 0 1 1 0 100 0 1 1 0 100 -1.041 0.477 1 0015666 restriction endodeoxyribonuclease activity F 0 0 0 0 0 0 1 2 0 50 -1.041 0.477 1 0009035 Type I site-specific deoxyribonuclease activity F 0 1 1 0 100 0 1 1 0 100 -1.041 0.477 1 0016888 endodeoxyribonuclease activity, producing 5’-phosphomonoesters F 0 0 1 0 0 0 1 3 0 33.33333 -1.041 0.477 1 0005496 steroid binding F 0 0 0 0 0 2 2 2 100 100 1.359 0.478 1 0015485 cholesterol binding F 2 2 2 100 100 2 2 2 100 100 1.359 0.478 1 0032934 sterol binding F 0 0 0 0 0 2 2 2 100 100 1.359 0.478 1 0043178 alcohol binding F 0 0 0 0 0 2 2 2 100 100 1.359 0.478 1 0050380 undecaprenyl-diphosphatase activity F 0 1 1 0 100 0 1 1 0 100 -1.041 0.478 1 0042026 protein refolding P 0 1 1 0 100 0 1 1 0 100 -1.041 0.478 1 0016868 intramolecular transferase activity, phosphotransferases F 1 1 3 100 33.33333 2 2 5 100 40 1.359 0.479 1 0015035 protein disulfide oxidoreductase activity F 2 2 3 100 66.66666 2 2 3 100 66.66666 1.359 0.479 1 0015036 disulfide oxidoreductase activity F 0 0 0 0 0 2 2 4 100 50 1.359 0.479 1 0031388 organic acid phosphorylation P 0 1 1 0 100 0 1 1 0 100 -1.041 0.479 1 0008887 glycerate kinase activity F 0 1 1 0 100 0 1 1 0 100 -1.041 0.479 1 0031119 tRNA pseudouridine synthesis P 2 2 2 100 100 2 2 2 100 100 1.359 0.48 1 0004766 spermidine synthase activity F 0 1 1 0 100 0 1 1 0 100 -1.041 0.48 1 0009025 tagatose-bisphosphate aldolase activity F 0 1 1 0 100 0 1 1 0 100 -1.041 0.48 1 0008184 glycogen phosphorylase activity F 0 1 1 0 100 0 1 1 0 100 -1.041 0.48 1 0015976 carbon utilization P 0 1 1 0 100 0 1 1 0 100 -1.041 0.48 1 0008295 spermidine biosynthetic process P 0 1 1 0 100 0 1 1 0 100 -1.041 0.48 1 0008216 spermidine metabolic process P 0 0 0 0 0 0 1 1 0 100 -1.041 0.48 1 0008774 acetaldehyde dehydrogenase (acetylating) activity F 0 1 1 0 100 0 1 1 0 100 -1.041 0.48 1 0016987 sigma factor activity F 0 1 3 0 33.33333 0 1 3 0 33.33333 -1.041 0.481 1 0000990 core RNA polymerase binding transcription factor activity F 0 0 0 0 0 0 1 3 0 33.33333 -1.041 0.481 1 0000996 core DNA-dependent RNA polymerase binding promoter specificity activity F 0 0 0 0 0 0 1 3 0 33.33333 -1.041 0.481 1 0006352 DNA-dependent transcription, initiation P 0 1 3 0 33.33333 0 1 3 0 33.33333 -1.041 0.481 1 0009263 deoxyribonucleotide biosynthetic process P 1 1 1 100 100 2 2 3 100 66.66666 1.359 0.482 1 0008270 zinc ion binding F 19 32 45 59.375 71.11111 19 32 45 59.375 71.11111 0.846 0.482 1 0004044 amidophosphoribosyltransferase activity F 0 1 1 0 100 0 1 1 0 100 -1.041 0.482 1 0009113 purine nucleobase biosynthetic process P 0 1 2 0 50 0 1 3 0 33.33333 -1.041 0.482 1 0051184 cofactor transporter activity F 0 0 0 0 0 0 1 1 0 100 -1.041 0.483 1 0051183 vitamin transporter activity F 0 0 0 0 0 0 1 2 0 50 -1.041 0.483 1 0051181 cofactor transport P 0 0 0 0 0 0 1 1 0 100 -1.041 0.483 1 0051180 vitamin transport P 0 0 0 0 0 0 1 2 0 50 -1.041 0.483 1 0015878 biotin transport P 0 1 1 0 100 0 1 1 0 100 -1.041 0.483 1 0015225 biotin transporter activity F 0 1 1 0 100 0 1 1 0 100 -1.041 0.483 1 0015718 monocarboxylic acid transport P 0 0 0 0 0 0 1 1 0 100 -1.041 0.483 1 0004489 methylenetetrahydrofolate reductase (NAD(P)H) activity F 0 1 1 0 100 0 1 1 0 100 -1.041 0.484 1 0016859 cis-trans isomerase activity F 0 0 0 0 0 2 2 4 100 50 1.359 0.485 1 0018208 peptidyl-proline modification P 0 0 0 0 0 2 2 4 100 50 1.359 0.485 1 0000413 protein peptidyl-prolyl isomerization P 2 2 4 100 50 2 2 4 100 50 1.359 0.485 1 0003755 peptidyl-prolyl cis-trans isomerase activity F 2 2 4 100 50 2 2 4 100 50 1.359 0.485 1 0004594 pantothenate kinase activity F 0 1 1 0 100 0 1 1 0 100 -1.041 0.485 1 0015299 solute:hydrogen antiporter activity F 0 1 1 0 100 0 1 1 0 100 -1.041 0.485 1 0015298 solute:cation antiporter activity F 0 0 0 0 0 0 1 1 0 100 -1.041 0.485 1 0008923 lysine decarboxylase activity F 0 1 1 0 100 0 1 1 0 100 -1.041 0.485 1 0016782 transferase activity, transferring sulfur-containing groups F 0 0 0 0 0 2 2 3 100 66.66666 1.359 0.486 1 0016783 sulfurtransferase activity F 2 2 2 100 100 2 2 3 100 66.66666 1.359 0.486 1 0043365 [formate-C-acetyltransferase]-activating enzyme activity F 2 2 3 100 66.66666 2 2 3 100 66.66666 1.359 0.487 1 0043364 catalysis of free radical formation F 0 0 0 0 0 2 2 3 100 66.66666 1.359 0.487 1 0019835 cytolysis P 2 2 2 100 100 2 2 2 100 100 1.359 0.487 1 0008219 cell death P 0 0 0 0 0 2 2 3 100 66.66666 1.359 0.487 1 0016265 death P 0 0 0 0 0 2 2 3 100 66.66666 1.359 0.487 1 0003746 translation elongation factor activity F 2 2 6 100 33.33333 2 2 6 100 33.33333 1.359 0.487 1 0019206 nucleoside kinase activity F 0 0 0 0 0 2 2 2 100 100 1.359 0.487 1 0070283 radical SAM enzyme activity F 0 0 0 0 0 2 2 3 100 66.66666 1.359 0.487 1 0004559 alpha-mannosidase activity F 0 1 1 0 100 0 1 1 0 100 -1.041 0.487 1 0006099 tricarboxylic acid cycle P 0 1 1 0 100 0 1 1 0 100 -1.041 0.487 1 0006107 oxaloacetate metabolic process P 0 1 1 0 100 0 1 1 0 100 -1.041 0.487 1 0046835 carbohydrate phosphorylation P 0 1 1 0 100 0 1 1 0 100 -1.041 0.487 1 0009060 aerobic respiration P 0 0 0 0 0 0 1 1 0 100 -1.041 0.487 1 0004335 galactokinase activity F 0 1 1 0 100 0 1 1 0 100 -1.041 0.487 1 0008964 phosphoenolpyruvate carboxylase activity F 0 1 1 0 100 0 1 1 0 100 -1.041 0.487 1 0015977 carbon fixation P 0 1 1 0 100 0 1 1 0 100 -1.041 0.487 1 0045333 cellular respiration P 0 0 0 0 0 0 1 1 0 100 -1.041 0.487 1 0015923 mannosidase activity F 0 0 0 0 0 0 1 1 0 100 -1.041 0.487 1 0004611 phosphoenolpyruvate carboxykinase activity F 0 0 0 0 0 0 1 1 0 100 -1.041 0.487 1 0003729 mRNA binding F 2 2 2 100 100 2 2 2 100 100 1.359 0.488 1 0070546 L-phenylalanine aminotransferase activity F 0 0 0 0 0 2 2 2 100 100 1.359 0.488 1 0080130 L-phenylalanine:2-oxoglutarate aminotransferase activity F 2 2 2 100 100 2 2 2 100 100 1.359 0.488 1 0003844 1,4-alpha-glucan branching enzyme activity F 0 1 1 0 100 0 1 1 0 100 -1.041 0.488 1 0004190 aspartic-type endopeptidase activity F 0 1 2 0 50 0 1 2 0 50 -1.041 0.488 1 0070001 aspartic-type peptidase activity F 0 0 0 0 0 0 1 2 0 50 -1.041 0.488 1 0006432 phenylalanyl-tRNA aminoacylation P 2 2 2 100 100 2 2 2 100 100 1.359 0.489 1 0004826 phenylalanine-tRNA ligase activity F 2 2 2 100 100 2 2 2 100 100 1.359 0.489 1 0046348 amino sugar catabolic process P 0 0 0 0 0 0 1 3 0 33.33333 -1.041 0.489 1 0019262 N-acetylneuraminate catabolic process P 0 1 3 0 33.33333 0 1 3 0 33.33333 -1.041 0.489 1 0006054 N-acetylneuraminate metabolic process P 0 0 0 0 0 0 1 3 0 33.33333 -1.041 0.489 1 0047465 N-acylglucosamine-6-phosphate 2-epimerase activity F 0 1 2 0 50 0 1 2 0 50 -1.041 0.489 1 0005326 neurotransmitter transporter activity F 0 0 0 0 0 0 1 1 0 100 -1.041 0.489 1 0006050 mannosamine metabolic process P 0 0 0 0 0 0 1 2 0 50 -1.041 0.489 1 0042085 5-methyltetrahydropteroyltri-L-glutamate-dependent methyltransferase activity F 0 0 0 0 0 0 1 1 0 100 -1.041 0.489 1 0033920 6-phospho-beta-galactosidase activity F 0 1 2 0 50 0 1 2 0 50 -1.041 0.489 1 0006051 N-acetylmannosamine metabolic process P 0 1 2 0 50 0 1 2 0 50 -1.041 0.489 1 0005328 neurotransmitter:sodium symporter activity F 0 1 1 0 100 0 1 1 0 100 -1.041 0.489 1 0008172 S-methyltransferase activity F 0 0 0 0 0 0 1 2 0 50 -1.041 0.489 1 0006836 neurotransmitter transport P 0 1 1 0 100 0 1 1 0 100 -1.041 0.489 1 0003871 5-methyltetrahydropteroyltriglutamate-homocysteine S-methyltransferase activity F 0 1 1 0 100 0 1 1 0 100 -1.041 0.489 1 0051537 2 iron, 2 sulfur cluster binding F 0 1 1 0 100 0 1 1 0 100 -1.041 0.49 1 0004312 fatty acid synthase activity F 0 0 0 0 0 2 2 4 100 50 1.359 0.491 1 0019563 glycerol catabolic process P 0 1 1 0 100 0 1 1 0 100 -1.041 0.491 1 0008840 4-hydroxy-tetrahydrodipicolinate synthase F 0 1 1 0 100 0 1 1 0 100 -1.041 0.491 1 0019405 alditol catabolic process P 0 0 0 0 0 0 1 1 0 100 -1.041 0.491 1 0000150 recombinase activity F 0 1 1 0 100 0 1 1 0 100 -1.041 0.491 1 0046174 polyol catabolic process P 0 0 0 0 0 0 1 1 0 100 -1.041 0.491 1 0046164 alcohol catabolic process P 0 0 0 0 0 0 1 1 0 100 -1.041 0.491 1 0016843 amine-lyase activity F 0 1 1 0 100 0 1 1 0 100 -1.041 0.491 1 0017169 CDP-alcohol phosphatidyltransferase activity F 0 0 0 0 0 0 1 1 0 100 -1.041 0.491 1 0008444 CDP-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase activity F 0 1 1 0 100 0 1 1 0 100 -1.041 0.491 1 0004370 glycerol kinase activity F 0 1 1 0 100 0 1 1 0 100 -1.041 0.491 1 0008859 exoribonuclease II activity F 0 1 1 0 100 0 1 1 0 100 -1.041 0.491 1 1901616 organic hydroxy compound catabolic process P 0 0 0 0 0 0 1 1 0 100 -1.041 0.491 1 0004368 glycerol-3-phosphate dehydrogenase activity F 0 1 1 0 100 0 1 1 0 100 -1.041 0.492 1 0016901 oxidoreductase activity, acting on the CH-OH group of donors, quinone or similar compound as acceptor F 0 0 0 0 0 0 1 1 0 100 -1.041 0.492 1 0016899 oxidoreductase activity, acting on the CH-OH group of donors, oxygen as acceptor F 0 0 0 0 0 0 1 1 0 100 -1.041 0.492 1 0031647 regulation of protein stability P 0 1 1 0 100 0 1 1 0 100 -1.041 0.492 1 0004369 glycerol-3-phosphate oxidase activity F 0 1 1 0 100 0 1 1 0 100 -1.041 0.492 1 0019104 DNA N-glycosylase activity F 0 0 1 0 0 2 2 4 100 50 1.359 0.493 1 0016799 hydrolase activity, hydrolyzing N-glycosyl compounds F 1 1 2 100 50 2 2 5 100 40 1.359 0.493 1 0004749 ribose phosphate diphosphokinase activity F 0 1 2 0 50 0 1 2 0 50 -1.041 0.493 1 0006015 5-phosphoribose 1-diphosphate biosynthetic process P 0 1 3 0 33.33333 0 1 3 0 33.33333 -1.041 0.493 1 0046391 5-phosphoribose 1-diphosphate metabolic process P 0 0 0 0 0 0 1 3 0 33.33333 -1.041 0.493 1 0006829 zinc ion transport P 2 2 2 100 100 2 2 2 100 100 1.359 0.494 1 0000041 transition metal ion transport P 0 0 0 0 0 2 2 2 100 100 1.359 0.494 1 0046374 teichoic acid metabolic process P 0 0 0 0 0 2 2 2 100 100 1.359 0.495 1 0046037 GMP metabolic process P 0 0 0 0 0 2 2 2 100 100 1.359 0.495 1 0005216 ion channel activity F 2 2 2 100 100 2 2 2 100 100 1.359 0.495 1 0022838 substrate-specific channel activity F 0 0 0 0 0 2 2 2 100 100 1.359 0.495 1 0015267 channel activity F 0 0 0 0 0 2 2 2 100 100 1.359 0.495 1 0070395 lipoteichoic acid biosynthetic process P 2 2 2 100 100 2 2 2 100 100 1.359 0.495 1 0006177 GMP biosynthetic process P 2 2 2 100 100 2 2 2 100 100 1.359 0.495 1 0022803 passive transmembrane transporter activity F 0 0 0 0 0 2 2 2 100 100 1.359 0.495 1 0047473 D-alanine-poly(phosphoribitol) ligase activity F 2 2 2 100 100 2 2 2 100 100 1.359 0.495 1 0019350 teichoic acid biosynthetic process P 2 2 2 100 100 2 2 2 100 100 1.359 0.495 1 0070394 lipoteichoic acid metabolic process P 0 0 0 0 0 2 2 2 100 100 1.359 0.495 1 0022607 cellular component assembly P 0 0 0 0 0 6 9 17 66.66666 52.94118 0.883 0.495 1 0004639 phosphoribosylaminoimidazolesuccinocarboxamide synthase activity F 0 1 1 0 100 0 1 1 0 100 -1.041 0.495 1 0042780 tRNA 3’-end processing P 0 0 0 0 0 0 1 2 0 50 -1.041 0.496 1 0004810 tRNA adenylyltransferase activity F 0 1 1 0 100 0 1 1 0 100 -1.041 0.496 1 0016437 tRNA cytidylyltransferase activity F 0 1 1 0 100 0 1 1 0 100 -1.041 0.496 1 0042245 RNA repair P 0 1 1 0 100 0 1 1 0 100 -1.041 0.496 1 0052927 CTP:tRNA cytidylyltransferase activity F 0 1 1 0 100 0 1 1 0 100 -1.041 0.496 1 0031123 RNA 3’-end processing P 0 0 0 0 0 0 1 2 0 50 -1.041 0.496 1 0052928 CTP:3’-cytidine-tRNA cytidylyltransferase activity F 0 1 1 0 100 0 1 1 0 100 -1.041 0.496 1 0043628 ncRNA 3’-end processing P 0 0 0 0 0 0 1 2 0 50 -1.041 0.496 1 0052929 ATP:3’-cytidine-cytidine-tRNA adenylyltransferase activity F 0 1 1 0 100 0 1 1 0 100 -1.041 0.496 1 0001680 tRNA 3’-terminal CCA addition P 0 1 1 0 100 0 1 1 0 100 -1.041 0.496 1 0051192 prosthetic group binding F 0 0 0 0 0 2 2 2 100 100 1.359 0.497 1 0000036 ACP phosphopantetheine attachment site binding involved in fatty acid biosynthetic process F 2 2 2 100 100 2 2 2 100 100 1.359 0.497 1 0044620 ACP phosphopantetheine attachment site binding F 0 0 0 0 0 2 2 2 100 100 1.359 0.497 1 0045017 glycerolipid biosynthetic process P 0 0 0 0 0 2 2 2 100 100 1.359 0.498 1 0046474 glycerophospholipid biosynthetic process P 0 0 0 0 0 2 2 2 100 100 1.359 0.498 1 0046654 tetrahydrofolate biosynthetic process P 2 2 4 100 50 2 2 4 100 50 1.359 0.498 1 0016838 carbon-oxygen lyase activity, acting on phosphates F 0 0 0 0 0 2 2 3 100 66.66666 1.359 0.498 1 0016757 transferase activity, transferring glycosyl groups F 5 16 26 31.25 61.53846 8 19 29 42.10526 65.51724 -0.872 0.498 1 0065009 regulation of molecular function P 0 0 0 0 0 2 2 2 100 100 1.359 0.499 1 0050790 regulation of catalytic activity P 1 1 1 100 100 2 2 2 100 100 1.359 0.499 1 0019808 polyamine binding F 0 1 1 0 100 0 1 1 0 100 -1.041 0.499 1 0006091 generation of precursor metabolites and energy P 0 0 0 0 0 6 9 15 66.66666 60 0.883 0.5 1 0048583 regulation of response to stimulus P 0 0 0 0 0 0 1 1 0 100 -1.041 0.5 1 2001020 regulation of response to DNA damage stimulus P 0 0 0 0 0 0 1 1 0 100 -1.041 0.5 1 0080135 regulation of cellular response to stress P 0 0 0 0 0 0 1 1 0 100 -1.041 0.5 1 0080134 regulation of response to stress P 0 0 0 0 0 0 1 1 0 100 -1.041 0.5 1 0006282 regulation of DNA repair P 0 1 1 0 100 0 1 1 0 100 -1.041 0.5 1 0009132 nucleoside diphosphate metabolic process P 0 0 0 0 0 2 2 3 100 66.66666 1.359 0.501 1 0016791 phosphatase activity F 0 0 0 0 0 2 2 2 100 100 1.359 0.501 1 0035335 peptidyl-tyrosine dephosphorylation P 2 2 2 100 100 2 2 2 100 100 1.359 0.501 1 0004721 phosphoprotein phosphatase activity F 1 1 1 100 100 2 2 2 100 100 1.359 0.501 1 0006470 protein dephosphorylation P 1 1 1 100 100 2 2 2 100 100 1.359 0.501 1 0004725 protein tyrosine phosphatase activity F 2 2 2 100 100 2 2 2 100 100 1.359 0.501 1 0030435 sporulation resulting in formation of a cellular spore P 0 1 1 0 100 0 1 1 0 100 -1.041 0.501 1 0048646 anatomical structure formation involved in morphogenesis P 0 0 0 0 0 0 1 1 0 100 -1.041 0.501 1 0008959 phosphate acetyltransferase activity F 0 1 1 0 100 0 1 1 0 100 -1.041 0.501 1 0030154 cell differentiation P 0 0 0 0 0 0 1 1 0 100 -1.041 0.501 1 0008745 N-acetylmuramoyl-L-alanine amidase activity F 0 1 1 0 100 0 1 1 0 100 -1.041 0.501 1 0043934 sporulation P 0 0 0 0 0 0 1 2 0 50 -1.041 0.501 1 0003906 DNA-(apurinic or apyrimidinic site) lyase activity F 2 2 2 100 100 2 2 2 100 100 1.359 0.503 1 0015175 neutral amino acid transmembrane transporter activity F 0 0 0 0 0 0 1 1 0 100 -1.041 0.503 1 0022858 alanine transmembrane transporter activity F 0 0 0 0 0 0 1 1 0 100 -1.041 0.503 1 0005294 neutral L-amino acid secondary active transmembrane transporter activity F 0 0 0 0 0 0 1 1 0 100 -1.041 0.503 1 0004462 lactoylglutathione lyase activity F 0 1 2 0 50 0 1 2 0 50 -1.041 0.503 1 0015804 neutral amino acid transport P 0 0 0 0 0 0 1 1 0 100 -1.041 0.503 1 0005283 sodium:amino acid symporter activity F 0 0 0 0 0 0 1 1 0 100 -1.041 0.503 1 0016846 carbon-sulfur lyase activity F 0 0 0 0 0 0 1 3 0 33.33333 -1.041 0.503 1 0032328 alanine transport P 0 1 1 0 100 0 1 1 0 100 -1.041 0.503 1 0006814 sodium ion transport P 0 1 1 0 100 0 1 1 0 100 -1.041 0.503 1 0015296 anion:cation symporter activity F 0 0 0 0 0 0 1 1 0 100 -1.041 0.503 1 0005343 organic acid:sodium symporter activity F 0 0 0 0 0 0 1 1 0 100 -1.041 0.503 1 0015655 alanine:sodium symporter activity F 0 1 1 0 100 0 1 1 0 100 -1.041 0.503 1 0005416 cation:amino acid symporter activity F 0 0 0 0 0 0 1 1 0 100 -1.041 0.503 1 0072594 establishment of protein localization to organelle P 0 0 0 0 0 2 2 2 100 100 1.359 0.505 1 0006614 SRP-dependent cotranslational protein targeting to membrane P 2 2 2 100 100 2 2 2 100 100 1.359 0.505 1 0006612 protein targeting to membrane P 2 2 2 100 100 2 2 2 100 100 1.359 0.505 1 0090150 establishment of protein localization to membrane P 0 0 0 0 0 2 2 2 100 100 1.359 0.505 1 0072657 protein localization to membrane P 0 0 0 0 0 2 2 2 100 100 1.359 0.505 1 0045047 protein targeting to ER P 0 0 0 0 0 2 2 2 100 100 1.359 0.505 1 0016482 cytoplasmic transport P 0 0 0 0 0 2 2 2 100 100 1.359 0.505 1 0072599 establishment of protein localization to endoplasmic reticulum P 0 0 0 0 0 2 2 2 100 100 1.359 0.505 1 0070972 protein localization to endoplasmic reticulum P 0 0 0 0 0 2 2 2 100 100 1.359 0.505 1 0033365 protein localization to organelle P 0 0 0 0 0 2 2 2 100 100 1.359 0.505 1 0006613 cotranslational protein targeting to membrane P 0 0 0 0 0 2 2 2 100 100 1.359 0.505 1 0010608 posttranscriptional regulation of gene expression P 0 0 0 0 0 6 9 11 66.66666 81.81818 0.883 0.505 1 0008408 3’-5’ exonuclease activity F 2 6 6 33.33333 100 3 8 8 37.5 100 -0.824 0.505 1 0015791 polyol transport P 0 0 0 0 0 0 1 1 0 100 -1.041 0.505 1 0015166 polyol transmembrane transporter activity F 0 0 0 0 0 0 1 1 0 100 -1.041 0.505 1 0015577 galactitol transmembrane transporter activity F 0 1 1 0 100 0 1 1 0 100 -1.041 0.505 1 0015796 galactitol transport P 0 1 1 0 100 0 1 1 0 100 -1.041 0.505 1 0015850 organic hydroxy compound transport P 0 0 0 0 0 0 1 1 0 100 -1.041 0.505 1 0015665 alcohol transmembrane transporter activity F 0 0 0 0 0 0 1 1 0 100 -1.041 0.505 1 1901618 organic hydroxy compound transmembrane transporter activity F 0 0 0 0 0 0 1 1 0 100 -1.041 0.505 1 0006664 glycolipid metabolic process P 0 0 0 0 0 2 2 2 100 100 1.359 0.506 1 0006643 membrane lipid metabolic process P 0 0 0 0 0 2 2 2 100 100 1.359 0.506 1 0016597 amino acid binding F 0 0 4 0 0 2 2 7 100 28.57143 1.359 0.506 1 0009312 oligosaccharide biosynthetic process P 0 0 0 0 0 2 2 2 100 100 1.359 0.506 1 0010035 response to inorganic substance P 0 0 0 0 0 2 2 2 100 100 1.359 0.506 1 1901271 lipooligosaccharide biosynthetic process P 0 0 0 0 0 2 2 2 100 100 1.359 0.506 1 1901269 lipooligosaccharide metabolic process P 0 0 0 0 0 2 2 2 100 100 1.359 0.506 1 0046493 lipid A metabolic process P 0 0 0 0 0 2 2 2 100 100 1.359 0.506 1 0046467 membrane lipid biosynthetic process P 0 0 0 0 0 2 2 2 100 100 1.359 0.506 1 0009247 glycolipid biosynthetic process P 0 0 0 0 0 2 2 2 100 100 1.359 0.506 1 0034618 arginine binding F 2 2 3 100 66.66666 2 2 3 100 66.66666 1.359 0.506 1 0009245 lipid A biosynthetic process P 2 2 2 100 100 2 2 2 100 100 1.359 0.506 1 0043822 ribonuclease M5 activity F 0 1 1 0 100 0 1 1 0 100 -1.041 0.507 1 0051276 chromosome organization P 1 1 1 100 100 2 2 2 100 100 1.359 0.509 1 0030261 chromosome condensation P 2 2 2 100 100 2 2 2 100 100 1.359 0.509 1 0030163 protein catabolic process P 2 2 2 100 100 2 2 2 100 100 1.359 0.509 1 0006323 DNA packaging P 0 0 0 0 0 2 2 2 100 100 1.359 0.509 1 0003920 GMP reductase activity F 0 1 1 0 100 0 1 1 0 100 -1.041 0.509 1 0009011 starch synthase activity F 0 1 1 0 100 0 1 1 0 100 -1.041 0.509 1 0046527 glucosyltransferase activity F 0 0 0 0 0 0 1 1 0 100 -1.041 0.509 1 0034035 purine ribonucleoside bisphosphate metabolic process P 0 0 0 0 0 2 2 2 100 100 1.359 0.51 1 0015969 guanosine tetraphosphate metabolic process P 2 2 2 100 100 2 2 2 100 100 1.359 0.51 1 0044247 cellular polysaccharide catabolic process P 0 0 0 0 0 0 1 1 0 100 -1.041 0.511 1 0042120 alginic acid metabolic process P 0 0 0 0 0 0 1 1 0 100 -1.041 0.511 1 0000272 polysaccharide catabolic process P 0 0 0 0 0 0 1 1 0 100 -1.041 0.511 1 0042122 alginic acid catabolic process P 0 1 1 0 100 0 1 1 0 100 -1.041 0.511 1 0045135 poly(beta-D-mannuronate) lyase activity F 0 1 1 0 100 0 1 1 0 100 -1.041 0.511 1 0016634 oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor F 0 0 0 0 0 2 2 3 100 66.66666 1.359 0.513 1 0016071 mRNA metabolic process P 0 0 0 0 0 2 2 3 100 66.66666 1.359 0.513 1 0016998 cell wall macromolecule catabolic process P 0 1 3 0 33.33333 0 1 3 0 33.33333 -1.041 0.513 1 0003796 lysozyme activity F 0 1 2 0 50 0 1 2 0 50 -1.041 0.513 1 0009306 protein secretion P 2 2 2 100 100 2 2 3 100 66.66666 1.359 0.516 1 0032940 secretion by cell P 0 0 0 0 0 2 2 3 100 66.66666 1.359 0.516 1 0046903 secretion P 0 0 0 0 0 2 2 3 100 66.66666 1.359 0.516 1 0003883 CTP synthase activity F 0 1 1 0 100 0 1 1 0 100 -1.041 0.516 1 0046901 tetrahydrofolylpolyglutamate biosynthetic process P 2 2 2 100 100 2 2 2 100 100 1.359 0.518 1 0004326 tetrahydrofolylpolyglutamate synthase activity F 2 2 2 100 100 2 2 2 100 100 1.359 0.518 1 0046900 tetrahydrofolylpolyglutamate metabolic process P 0 0 0 0 0 2 2 2 100 100 1.359 0.518 1 0009452 7-methylguanosine RNA capping P 0 0 0 0 0 2 2 2 100 100 1.359 0.519 1 0009295 nucleoid C 2 2 2 100 100 2 2 2 100 100 1.359 0.519 1 0036260 RNA capping P 0 0 0 0 0 2 2 2 100 100 1.359 0.519 1 0036265 RNA (guanine-N7)-methylation P 1 1 1 100 100 2 2 2 100 100 1.359 0.519 1 0008761 UDP-N-acetylglucosamine 2-epimerase activity F 2 2 2 100 100 2 2 2 100 100 1.359 0.52 1 0030246 carbohydrate binding F 4 10 12 40 83.33334 4 10 13 40 76.92308 -0.764 0.52 1 0006004 fucose metabolic process P 0 1 1 0 100 0 1 1 0 100 -1.041 0.52 1 0008736 L-fucose isomerase activity F 0 1 1 0 100 0 1 1 0 100 -1.041 0.52 1 0019317 fucose catabolic process P 0 1 1 0 100 0 1 1 0 100 -1.041 0.52 1 0009206 purine ribonucleoside triphosphate biosynthetic process P 0 0 0 0 0 6 9 12 66.66666 75 0.883 0.522 1 0009145 purine nucleoside triphosphate biosynthetic process P 0 0 0 0 0 6 9 12 66.66666 75 0.883 0.522 1 0006950 response to stress P 3 7 8 42.85714 87.5 20 43 58 46.51163 74.13793 -0.737 0.522 1 0006164 purine nucleotide biosynthetic process P 5 9 11 55.55556 81.81818 15 25 34 60 73.52941 0.809 0.524 1 0042083 5,10-methylenetetrahydrofolate-dependent methyltransferase activity F 0 0 0 0 0 2 2 2 100 100 1.359 0.528 1 0016728 oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor F 0 0 0 0 0 2 2 3 100 66.66666 1.359 0.529 1 0008080 N-acetyltransferase activity F 9 17 24 52.94118 70.83334 12 20 27 60 74.07407 0.722 0.535 1 0016410 N-acyltransferase activity F 0 0 0 0 0 12 20 27 60 74.07407 0.722 0.535 1 0004525 ribonuclease III activity F 2 2 2 100 100 2 2 2 100 100 1.359 0.538 1 0044459 plasma membrane part C 0 0 0 0 0 4 10 12 40 83.33334 -0.764 0.543 1 0005975 carbohydrate metabolic process P 16 48 70 33.33333 68.57143 38 78 109 48.71795 71.55963 -0.605 0.547 1 0010468 regulation of gene expression P 0 0 0 0 0 33 69 103 47.82609 66.99029 -0.72 0.549 1 0043492 ATPase activity, coupled to movement of substances F 0 0 0 0 0 12 26 35 46.15385 74.28571 -0.605 0.56 1 0042626 ATPase activity, coupled to transmembrane movement of substances F 4 15 18 26.66667 83.33334 12 26 35 46.15385 74.28571 -0.605 0.56 1 0060255 regulation of macromolecule metabolic process P 0 0 0 0 0 34 71 105 47.88733 67.61905 -0.72 0.56 1 0016779 nucleotidyltransferase activity F 12 21 26 57.14286 80.76923 14 24 30 58.33333 80 0.627 0.561 1 0006812 cation transport P 4 7 9 57.14286 77.77778 16 27 33 59.25926 81.81818 0.763 0.562 1 0050896 response to stimulus P 0 0 0 0 0 43 88 115 48.86364 76.52174 -0.617 0.567 1 0016835 carbon-oxygen lyase activity F 0 0 0 0 0 8 13 18 61.53846 72.22222 0.692 0.574 1 0004558 alpha-glucosidase activity F 0 0 0 0 0 1 3 3 33.33333 100 -0.648 0.575 1 0046943 carboxylic acid transmembrane transporter activity F 0 0 0 0 0 1 3 4 33.33333 75 -0.648 0.588 1 0005342 organic acid transmembrane transporter activity F 0 0 0 0 0 1 3 4 33.33333 75 -0.648 0.588 1 0006865 amino acid transport P 0 1 2 0 50 1 3 5 33.33333 60 -0.648 0.588 1 0015171 amino acid transmembrane transporter activity F 0 0 1 0 0 1 3 4 33.33333 75 -0.648 0.588 1 0008514 organic anion transmembrane transporter activity F 0 0 0 0 0 1 3 4 33.33333 75 -0.648 0.588 1 0009063 cellular amino acid catabolic process P 0 0 0 0 0 1 3 5 33.33333 60 -0.648 0.589 1 1901606 alpha-amino acid catabolic process P 0 0 0 0 0 1 3 5 33.33333 60 -0.648 0.589 1 0016780 phosphotransferase activity, for other substituted phosphate groups F 1 2 2 50 100 3 4 4 75 100 0.922 0.594 1 0052646 alditol phosphate metabolic process P 0 0 0 0 0 1 3 3 33.33333 100 -0.648 0.594 1 0006072 glycerol-3-phosphate metabolic process P 1 3 3 33.33333 100 1 3 3 33.33333 100 -0.648 0.594 1 0006351 transcription, DNA-dependent P 22 40 62 55 64.51613 28 58 90 48.27586 64.44444 -0.586 0.595 1 0003697 single-stranded DNA binding F 1 3 4 33.33333 75 1 3 4 33.33333 75 -0.648 0.596 1 0008237 metallopeptidase activity F 4 7 13 57.14286 53.84615 8 13 20 61.53846 65 0.692 0.598 1 0006650 glycerophospholipid metabolic process P 1 2 2 50 100 3 4 5 75 80 0.922 0.6 1 0044205 ’de novo’ UMP biosynthetic process P 3 4 9 75 44.44444 3 4 9 75 44.44444 0.922 0.6 1 0046486 glycerolipid metabolic process P 0 0 0 0 0 3 4 5 75 80 0.922 0.6 1 0006573 valine metabolic process P 0 0 0 0 0 1 3 4 33.33333 75 -0.648 0.6 1 0009099 valine biosynthetic process P 1 3 4 33.33333 75 1 3 4 33.33333 75 -0.648 0.6 1 0033177 proton-transporting two-sector ATPase complex, proton-transporting domain C 1 2 2 50 100 1 3 5 33.33333 60 -0.648 0.602 1 0005618 cell wall C 5 12 14 41.66667 85.71429 5 12 14 41.66667 85.71429 -0.721 0.604 1 0006364 rRNA processing P 9 14 15 64.28571 93.33334 9 15 16 60 93.75 0.623 0.605 1 0016072 rRNA metabolic process P 0 0 0 0 0 9 15 16 60 93.75 0.623 0.605 1 0032774 RNA biosynthetic process P 0 0 0 0 0 29 60 93 48.33333 64.51613 -0.587 0.605 1 0015238 drug transmembrane transporter activity F 1 3 3 33.33333 100 1 3 3 33.33333 100 -0.648 0.605 1 0006855 drug transmembrane transport P 1 3 3 33.33333 100 1 3 3 33.33333 100 -0.648 0.605 1 0090484 drug transporter activity F 0 0 0 0 0 1 3 3 33.33333 100 -0.648 0.605 1 0008173 RNA methyltransferase activity F 3 6 6 50 100 8 13 14 61.53846 92.85714 0.692 0.61 1 0009150 purine ribonucleotide metabolic process P 0 0 0 0 0 48 98 127 48.97959 77.16535 -0.631 0.61 1 0071806 protein transmembrane transport P 0 0 0 0 0 1 3 5 33.33333 60 -0.648 0.61 1 0065002 intracellular protein transmembrane transport P 1 3 4 33.33333 75 1 3 4 33.33333 75 -0.648 0.61 1 0010629 negative regulation of gene expression P 0 0 0 0 0 3 4 7 75 57.14286 0.922 0.612 1 0051172 negative regulation of nitrogen compound metabolic process P 0 0 0 0 0 3 4 7 75 57.14286 0.922 0.612 1 0045934 negative regulation of nucleobase-containing compound metabolic process P 0 0 0 0 0 3 4 7 75 57.14286 0.922 0.612 1 0045892 negative regulation of transcription, DNA-dependent P 3 4 7 75 57.14286 3 4 7 75 57.14286 0.922 0.612 1 0051253 negative regulation of RNA metabolic process P 0 0 0 0 0 3 4 7 75 57.14286 0.922 0.612 1 0043623 cellular protein complex assembly P 0 0 0 0 0 1 3 4 33.33333 75 -0.648 0.612 1 0046653 tetrahydrofolate metabolic process P 0 0 0 0 0 3 4 7 75 57.14286 0.922 0.614 1 0003916 DNA topoisomerase activity F 3 4 5 75 80 3 4 5 75 80 0.922 0.616 1 0006265 DNA topological change P 3 4 5 75 80 3 4 5 75 80 0.922 0.616 1 0009262 deoxyribonucleotide metabolic process P 0 0 0 0 0 3 4 6 75 66.66666 0.922 0.618 1 0016832 aldehyde-lyase activity F 0 0 2 0 0 1 3 7 33.33333 42.85714 -0.648 0.618 1 0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen F 0 1 1 0 100 1 3 3 33.33333 100 -0.648 0.618 1 0090305 nucleic acid phosphodiester bond hydrolysis P 10 17 23 58.82353 73.91304 10 17 24 58.82353 70.83334 0.567 0.619 1 0007059 chromosome segregation P 3 4 6 75 66.66666 3 4 6 75 66.66666 0.922 0.621 1 0006071 glycerol metabolic process P 1 3 5 33.33333 60 1 3 5 33.33333 60 -0.648 0.621 1 0002161 aminoacyl-tRNA editing activity F 3 4 5 75 80 3 4 5 75 80 0.922 0.623 1 0009381 excinuclease ABC activity F 1 3 3 33.33333 100 1 3 3 33.33333 100 -0.648 0.623 1 0004527 exonuclease activity F 7 11 11 63.63636 100 9 15 15 60 100 0.623 0.624 1 0015077 monovalent inorganic cation transmembrane transporter activity F 0 0 0 0 0 6 14 18 42.85714 77.77778 -0.69 0.626 1 0006401 RNA catabolic process P 1 2 3 50 66.66666 3 4 6 75 66.66666 0.922 0.629 1 0006259 DNA metabolic process P 2 3 5 66.66666 60 40 81 100 49.38272 81 -0.493 0.629 1 0015833 peptide transport P 3 3 7 100 42.85714 3 4 8 75 50 0.922 0.63 1 0004802 transketolase activity F 1 3 3 33.33333 100 1 3 3 33.33333 100 -0.648 0.63 1 0005829 cytosol C 0 1 1 0 100 1 3 4 33.33333 75 -0.648 0.632 1 0009209 pyrimidine ribonucleoside triphosphate biosynthetic process P 0 0 0 0 0 3 4 4 75 100 0.922 0.633 1 0046036 CTP metabolic process P 0 0 0 0 0 3 4 4 75 100 0.922 0.633 1 0009208 pyrimidine ribonucleoside triphosphate metabolic process P 0 0 0 0 0 3 4 4 75 100 0.922 0.633 1 0006241 CTP biosynthetic process P 1 1 1 100 100 3 4 4 75 100 0.922 0.633 1 0006526 arginine biosynthetic process P 3 4 6 75 66.66666 3 4 6 75 66.66666 0.922 0.635 1 0006730 one-carbon metabolic process P 3 4 6 75 66.66666 3 4 6 75 66.66666 0.922 0.638 1 0006560 proline metabolic process P 0 0 0 0 0 1 3 3 33.33333 100 -0.648 0.64 1 0006561 proline biosynthetic process P 1 3 3 33.33333 100 1 3 3 33.33333 100 -0.648 0.64 1 0009168 purine ribonucleoside monophosphate biosynthetic process P 0 0 0 0 0 10 17 26 58.82353 65.38461 0.567 0.642 1 0016052 carbohydrate catabolic process P 0 0 0 0 0 10 17 24 58.82353 70.83334 0.567 0.642 1 0044724 single-organism carbohydrate catabolic process P 0 0 0 0 0 10 17 24 58.82353 70.83334 0.567 0.642 1 0009127 purine nucleoside monophosphate biosynthetic process P 0 0 0 0 0 10 17 26 58.82353 65.38461 0.567 0.642 1 0042357 thiamine diphosphate metabolic process P 0 0 0 0 0 2 5 6 40 83.33334 -0.539 0.648 1 0009229 thiamine diphosphate biosynthetic process P 2 5 6 40 83.33334 2 5 6 40 83.33334 -0.539 0.648 1 0019200 carbohydrate kinase activity F 0 0 0 0 0 2 5 6 40 83.33334 -0.539 0.649 1 0032153 cell division site C 1 3 3 33.33333 100 1 3 3 33.33333 100 -0.648 0.649 1 0019954 asexual reproduction P 0 0 0 0 0 1 3 3 33.33333 100 -0.648 0.649 1 0000003 reproduction P 0 0 0 0 0 1 3 3 33.33333 100 -0.648 0.649 1 0032505 reproduction of a single-celled organism P 0 0 0 0 0 1 3 3 33.33333 100 -0.648 0.649 1 0043093 cytokinesis by binary fission P 1 3 3 33.33333 100 1 3 3 33.33333 100 -0.648 0.649 1 0000910 cytokinesis P 0 0 0 0 0 1 3 8 33.33333 37.5 -0.648 0.649 1 0016891 endoribonuclease activity, producing 5’-phosphomonoesters F 0 0 1 0 0 3 4 7 75 57.14286 0.922 0.65 1 0051259 protein oligomerization P 2 2 3 100 66.66666 3 4 5 75 80 0.922 0.652 1 0051287 NAD binding F 3 4 5 75 80 3 4 5 75 80 0.922 0.653 1 0006541 glutamine metabolic process P 3 5 7 60 71.42857 4 6 8 66.66666 75 0.72 0.66 1 0030145 manganese ion binding F 4 6 12 66.66666 50 4 6 12 66.66666 50 0.72 0.67 1 0019751 polyol metabolic process P 1 1 1 100 100 2 5 7 40 71.42857 -0.539 0.673 1 0016667 oxidoreductase activity, acting on a sulfur group of donors F 0 0 0 0 0 4 6 9 66.66666 66.66666 0.72 0.676 1 0046907 intracellular transport P 0 0 0 0 0 4 6 7 66.66666 85.71429 0.72 0.682 1 0006605 protein targeting P 2 4 5 50 80 4 6 7 66.66666 85.71429 0.72 0.682 1 0006886 intracellular protein transport P 2 3 3 66.66666 100 4 6 7 66.66666 85.71429 0.72 0.682 1 0006188 IMP biosynthetic process P 0 0 0 0 0 2 5 9 40 55.55556 -0.539 0.682 1 0046040 IMP metabolic process P 0 0 0 0 0 2 5 9 40 55.55556 -0.539 0.682 1 0006189 ’de novo’ IMP biosynthetic process P 2 5 8 40 62.5 2 5 8 40 62.5 -0.539 0.682 1 0009147 pyrimidine nucleoside triphosphate metabolic process P 0 0 0 0 0 4 6 7 66.66666 85.71429 0.72 0.683 1 0016861 intramolecular oxidoreductase activity, interconverting aldoses and ketoses F 0 1 3 0 33.33333 4 6 10 66.66666 60 0.72 0.683 1 0016860 intramolecular oxidoreductase activity F 0 0 0 0 0 4 6 11 66.66666 54.54546 0.72 0.683 1 0006261 DNA-dependent DNA replication P 1 2 3 50 66.66666 4 6 7 66.66666 85.71429 0.72 0.687 1 0006457 protein folding P 4 6 11 66.66666 54.54546 4 6 11 66.66666 54.54546 0.72 0.688 1 0046451 diaminopimelate metabolic process P 0 0 0 0 0 4 6 7 66.66666 85.71429 0.72 0.688 1 0009085 lysine biosynthetic process P 3 5 5 60 100 4 6 7 66.66666 85.71429 0.72 0.688 1 0009089 lysine biosynthetic process via diaminopimelate P 4 6 7 66.66666 85.71429 4 6 7 66.66666 85.71429 0.72 0.688 1 0006553 lysine metabolic process P 0 0 0 0 0 4 6 7 66.66666 85.71429 0.72 0.688 1 0019693 ribose phosphate metabolic process P 0 0 0 0 0 53 106 143 50 74.12588 -0.437 0.688 1 0033178 proton-transporting two-sector ATPase complex, catalytic domain C 2 4 4 50 100 4 6 7 66.66666 85.71429 0.72 0.689 1 0016744 transferase activity, transferring aldehyde or ketonic groups F 0 0 0 0 0 2 5 5 40 100 -0.539 0.69 1 0016814 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines F 0 0 0 0 0 2 5 7 40 71.42857 -0.539 0.694 1 0045454 cell redox homeostasis P 4 6 8 66.66666 75 4 6 8 66.66666 75 0.72 0.696 1 0015405 P-P-bond-hydrolysis-driven transmembrane transporter activity F 0 0 0 0 0 14 29 38 48.27586 76.31579 -0.408 0.697 1 0015399 primary active transmembrane transporter activity F 0 0 0 0 0 14 29 38 48.27586 76.31579 -0.408 0.697 1 0004536 deoxyribonuclease activity F 0 0 0 0 0 3 7 9 42.85714 77.77778 -0.486 0.71 1 0044265 cellular macromolecule catabolic process P 0 0 0 0 0 4 6 8 66.66666 75 0.72 0.711 1 0065003 macromolecular complex assembly P 0 0 0 0 0 5 8 10 62.5 80 0.596 0.715 1 0009084 glutamine family amino acid biosynthetic process P 0 0 0 0 0 5 8 10 62.5 80 0.596 0.72 1 0008509 anion transmembrane transporter activity F 0 0 0 0 0 5 8 11 62.5 72.72727 0.596 0.72 1 0055114 oxidation-reduction process P 38 69 90 55.07246 76.66666 41 75 98 54.66667 76.53061 0.478 0.726 1 0015991 ATP hydrolysis coupled proton transport P 3 7 7 42.85714 100 3 7 7 42.85714 100 -0.486 0.729 1 0015988 energy coupled proton transmembrane transport, against electrochemical gradient P 0 0 0 0 0 3 7 7 42.85714 100 -0.486 0.729 1 0019222 regulation of metabolic process P 0 0 0 0 0 36 73 110 49.31507 66.36364 -0.478 0.73 1 0006817 phosphate ion transport P 3 6 9 50 66.66666 5 8 12 62.5 66.66666 0.596 0.731 1 0043566 structure-specific DNA binding F 0 0 0 0 0 3 7 9 42.85714 77.77778 -0.486 0.732 1 0015986 ATP synthesis coupled proton transport P 5 5 8 100 62.5 5 8 11 62.5 72.72727 0.596 0.736 1 0015985 energy coupled proton transport, down electrochemical gradient P 0 0 0 0 0 5 8 11 62.5 72.72727 0.596 0.736 1 0006754 ATP biosynthetic process P 5 8 11 62.5 72.72727 5 8 11 62.5 72.72727 0.596 0.736 1 0016831 carboxy-lyase activity F 2 3 4 66.66666 75 5 8 10 62.5 80 0.596 0.737 1 0016765 transferase activity, transferring alkyl or aryl (other than methyl) groups F 2 2 4 100 50 5 8 14 62.5 57.14286 0.596 0.739 1 0050794 regulation of cellular process P 0 0 0 0 0 53 99 146 53.53535 67.80822 0.319 0.739 1 0008238 exopeptidase activity F 0 0 0 0 0 5 8 13 62.5 61.53846 0.596 0.743 1 0034061 DNA polymerase activity F 0 0 0 0 0 4 9 9 44.44444 100 -0.456 0.747 1 0003887 DNA-directed DNA polymerase activity F 4 9 9 44.44444 100 4 9 9 44.44444 100 -0.456 0.747 1 0016854 racemase and epimerase activity F 0 0 0 0 0 6 10 14 60 71.42857 0.508 0.748 1 0009292 genetic transfer P 0 0 0 0 0 5 11 11 45.45454 100 -0.437 0.752 1 0044764 multi-organism cellular process P 0 0 0 0 0 5 11 12 45.45454 91.66666 -0.437 0.752 1 0009294 DNA mediated transformation P 0 1 1 0 100 5 11 11 45.45454 100 -0.437 0.752 1 0065007 biological regulation P 0 0 0 0 0 58 108 159 53.7037 67.92453 0.372 0.754 1 0030170 pyridoxal phosphate binding F 7 12 15 58.33333 80 7 12 15 58.33333 80 0.441 0.758 1 0009064 glutamine family amino acid metabolic process P 0 0 0 0 0 8 14 19 57.14286 73.68421 0.387 0.761 1 0009259 ribonucleotide metabolic process P 0 0 0 0 0 53 105 140 50.47619 75 -0.332 0.765 1 0009067 aspartate family amino acid biosynthetic process P 0 0 0 0 0 4 9 15 44.44444 60 -0.456 0.768 1 0009066 aspartate family amino acid metabolic process P 0 0 0 0 0 4 9 15 44.44444 60 -0.456 0.768 1 0015078 hydrogen ion transmembrane transporter activity F 1 3 5 33.33333 60 5 11 14 45.45454 78.57143 -0.437 0.77 1 0071705 nitrogen compound transport P 0 0 0 0 0 5 11 19 45.45454 57.89474 -0.437 0.774 1 0030554 adenyl nucleotide binding F 3 3 5 100 60 109 205 270 53.17073 75.92593 0.37 0.783 1 0000156 phosphorelay response regulator activity F 7 12 14 58.33333 85.71429 7 12 14 58.33333 85.71429 0.441 0.787 1 0035556 intracellular signal transduction P 7 12 14 58.33333 85.71429 7 12 15 58.33333 80 0.441 0.787 1 0015672 monovalent inorganic cation transport P 0 0 0 0 0 8 14 18 57.14286 77.77778 0.387 0.788 1 1902494 catalytic complex C 0 0 0 0 0 9 16 19 56.25 84.21053 0.342 0.79 1 0034220 ion transmembrane transport P 1 2 3 50 66.66666 9 16 25 56.25 64 0.342 0.802 1 0030312 external encapsulating structure C 0 0 0 0 0 6 13 16 46.15385 81.25 -0.425 0.805 1 0016810 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds F 3 3 6 100 50 8 14 21 57.14286 66.66666 0.387 0.808 1 0006310 DNA recombination P 8 13 19 61.53846 68.42105 10 21 29 47.61905 72.4138 -0.407 0.809 1 0080090 regulation of primary metabolic process P 0 0 0 0 0 33 66 99 50 66.66666 -0.338 0.811 1 0031323 regulation of cellular metabolic process P 0 0 0 0 0 33 66 100 50 66 -0.338 0.811 1 0004175 endopeptidase activity F 0 0 0 0 0 8 17 26 47.05882 65.38461 -0.412 0.811 1 0006820 anion transport P 0 0 0 0 0 8 14 22 57.14286 63.63636 0.387 0.819 1 0046128 purine ribonucleoside metabolic process P 0 0 0 0 0 48 95 122 50.52632 77.86885 -0.304 0.826 1 0072527 pyrimidine-containing compound metabolic process P 0 0 0 0 0 11 20 31 55 64.51613 0.27 0.834 1 0009116 nucleoside metabolic process P 4 5 12 80 41.66667 59 111 148 53.15315 75 0.255 0.843 1 1901657 glycosyl compound metabolic process P 0 0 0 0 0 59 111 148 53.15315 75 0.255 0.843 1 0006796 phosphate-containing compound metabolic process P 0 0 0 0 0 99 188 257 52.65957 73.15175 0.196 0.85 1 0072521 purine-containing compound metabolic process P 0 0 0 0 0 54 106 137 50.9434 77.37226 -0.232 0.852 1 0070011 peptidase activity, acting on L-amino acid peptides F 0 0 0 0 0 13 26 40 50 65 -0.208 0.856 1 0016829 lyase activity F 16 32 47 50 68.08511 18 36 53 50 67.92453 -0.246 0.86 1 0044699 single-organism process P 0 0 0 0 0 123 234 321 52.5641 72.89719 0.192 0.872 1 0008233 peptidase activity F 10 18 26 55.55556 69.23077 19 35 49 54.28571 71.42857 0.274 0.874 1 0004518 nuclease activity F 10 17 24 58.82353 70.83334 17 31 41 54.83871 75.60976 0.32 0.879 1 0050789 regulation of biological process P 0 0 0 0 0 56 106 155 52.83019 68.3871 0.178 0.908 1 0009889 regulation of biosynthetic process P 0 0 0 0 0 33 65 97 50.76923 67.01031 -0.207 0.915 1 2000112 regulation of cellular macromolecule biosynthetic process P 0 0 0 0 0 33 65 97 50.76923 67.01031 -0.207 0.915 1 0010556 regulation of macromolecule biosynthetic process P 0 0 0 0 0 33 65 97 50.76923 67.01031 -0.207 0.915 1 0031326 regulation of cellular biosynthetic process P 0 0 0 0 0 33 65 97 50.76923 67.01031 -0.207 0.915 1 0006793 phosphorus metabolic process P 0 0 0 0 0 99 189 258 52.38095 73.25581 0.112 0.917 1 0042278 purine nucleoside metabolic process P 1 1 1 100 100 49 96 123 51.04167 78.04878 -0.2 0.922 1 0032559 adenyl ribonucleotide binding F 0 0 0 0 0 106 202 264 52.47525 76.51515 0.147 0.944 1 0005524 ATP binding F 106 202 264 52.47525 76.51515 106 202 264 52.47525 76.51515 0.147 0.944 1 0044427 chromosomal part C 0 0 0 0 0 1 1 1 100 100 0.961 1 1 0006875 cellular metal ion homeostasis P 0 0 0 0 0 1 1 1 100 100 0.961 1 1 0004340 glucokinase activity F 1 1 1 100 100 1 1 1 100 100 0.961 1 1 0046655 folic acid metabolic process P 0 0 0 0 0 1 1 2 100 50 0.961 1 1 0046916 cellular transition metal ion homeostasis P 0 0 0 0 0 1 1 1 100 100 0.961 1 1 0005657 replication fork C 0 0 0 0 0 1 1 1 100 100 0.961 1 1 0008762 UDP-N-acetylmuramate dehydrogenase activity F 1 1 1 100 100 1 1 1 100 100 0.961 1 1 0048878 chemical homeostasis P 0 0 0 0 0 1 1 4 100 25 0.961 1 1 0047661 amino-acid racemase activity F 0 0 0 0 0 1 1 2 100 50 0.961 1 1 0006165 nucleoside diphosphate phosphorylation P 1 1 1 100 100 1 1 1 100 100 0.961 1 1 0006571 tyrosine biosynthetic process P 1 1 1 100 100 1 1 1 100 100 0.961 1 1 0004550 nucleoside diphosphate kinase activity F 1 1 1 100 100 1 1 1 100 100 0.961 1 1 0032993 protein-DNA complex C 0 0 0 0 0 1 1 1 100 100 0.961 1 1 0005247 voltage-gated chloride channel activity F 1 1 1 100 100 1 1 1 100 100 0.961 1 1 0050801 ion homeostasis P 0 0 0 0 0 1 1 4 100 25 0.961 1 1 0030288 outer membrane-bounded periplasmic space C 1 1 2 100 50 1 1 2 100 50 0.961 1 1 0055082 cellular chemical homeostasis P 0 0 0 0 0 1 1 3 100 33.33333 0.961 1 1 0006873 cellular ion homeostasis P 0 0 0 0 0 1 1 3 100 33.33333 0.961 1 1 0016730 oxidoreductase activity, acting on iron-sulfur proteins as donors F 0 0 0 0 0 1 1 1 100 100 0.961 1 1 0006821 chloride transport P 1 1 1 100 100 1 1 1 100 100 0.961 1 1 0016731 oxidoreductase activity, acting on iron-sulfur proteins as donors, NAD or NADP as acceptor F 0 0 0 0 0 1 1 1 100 100 0.961 1 1 0030258 lipid modification P 0 0 0 0 0 1 1 2 100 50 0.961 1 1 0008766 UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity F 1 1 1 100 100 1 1 1 100 100 0.961 1 1 0030313 cell envelope C 0 0 0 0 0 1 1 2 100 50 0.961 1 1 0019521 D-gluconate metabolic process P 1 1 1 100 100 1 1 1 100 100 0.961 1 1 0031975 envelope C 0 0 0 0 0 1 1 2 100 50 0.961 1 1 0008977 prephenate dehydrogenase activity F 1 1 1 100 100 1 1 1 100 100 0.961 1 1 0004665 prephenate dehydrogenase (NADP+) activity F 1 1 1 100 100 1 1 1 100 100 0.961 1 1 0004616 phosphogluconate dehydrogenase (decarboxylating) activity F 1 1 1 100 100 1 1 1 100 100 0.961 1 1 0047480 UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity F 1 1 1 100 100 1 1 1 100 100 0.961 1 1 0051156 glucose 6-phosphate metabolic process P 1 1 1 100 100 1 1 1 100 100 0.961 1 1 0030003 cellular cation homeostasis P 0 0 0 0 0 1 1 1 100 100 0.961 1 1 0004827 proline-tRNA ligase activity F 1 1 1 100 100 1 1 1 100 100 0.961 1 1 0016075 rRNA catabolic process P 1 1 1 100 100 1 1 1 100 100 0.961 1 1 0004795 threonine synthase activity F 1 1 1 100 100 1 1 1 100 100 0.961 1 1 0030272 5-formyltetrahydrofolate cyclo-ligase activity F 1 1 1 100 100 1 1 1 100 100 0.961 1 1 0004814 arginine-tRNA ligase activity F 1 1 1 100 100 1 1 1 100 100 0.961 1 1 0006420 arginyl-tRNA aminoacylation P 1 1 1 100 100 1 1 1 100 100 0.961 1 1 0031072 heat shock protein binding F 1 1 1 100 100 1 1 1 100 100 0.961 1 1 0046690 response to tellurium ion P 1 1 1 100 100 1 1 1 100 100 0.961 1 1 0004713 protein tyrosine kinase activity F 1 1 1 100 100 1 1 1 100 100 0.961 1 1 0004715 non-membrane spanning protein tyrosine kinase activity F 1 1 1 100 100 1 1 1 100 100 0.961 1 1 0018108 peptidyl-tyrosine phosphorylation P 1 1 1 100 100 1 1 1 100 100 0.961 1 1 0030234 enzyme regulator activity F 1 1 1 100 100 1 1 2 100 50 0.961 1 1 0070548 L-glutamine aminotransferase activity F 0 0 0 0 0 1 1 1 100 100 0.961 1 1 0006419 alanyl-tRNA aminoacylation P 1 1 1 100 100 1 1 1 100 100 0.961 1 1 0009408 response to heat P 1 1 1 100 100 1 1 1 100 100 0.961 1 1 0009079 pyruvate family amino acid biosynthetic process P 0 0 0 0 0 1 1 1 100 100 0.961 1 1 0006662 glycerol ether metabolic process P 1 1 2 100 50 1 1 2 100 50 0.961 1 1 0006433 prolyl-tRNA aminoacylation P 1 1 1 100 100 1 1 1 100 100 0.961 1 1 0046144 D-alanine family amino acid metabolic process P 0 0 0 0 0 1 1 1 100 100 0.961 1 1 0019365 pyridine nucleotide salvage P 0 0 0 0 0 1 1 1 100 100 0.961 1 1 0070006 metalloaminopeptidase activity F 1 1 1 100 100 1 1 1 100 100 0.961 1 1 0070084 protein initiator methionine removal P 1 1 1 100 100 1 1 1 100 100 0.961 1 1 0060090 binding, bridging F 0 0 0 0 0 1 1 1 100 100 0.961 1 1 0018212 peptidyl-tyrosine modification P 0 0 0 0 0 1 1 1 100 100 0.961 1 1 0070925 organelle assembly P 0 0 0 0 0 1 1 2 100 50 0.961 1 1 0008194 UDP-glycosyltransferase activity F 0 0 0 0 0 1 1 1 100 100 0.961 1 1 0008534 oxidized purine nucleobase lesion DNA N-glycosylase activity F 1 1 1 100 100 1 1 1 100 100 0.961 1 1 0031365 N-terminal protein amino acid modification P 0 0 0 0 0 1 1 1 100 100 0.961 1 1 0006473 protein acetylation P 0 0 0 0 0 1 1 1 100 100 0.961 1 1 0003917 DNA topoisomerase type I activity F 1 1 1 100 100 1 1 1 100 100 0.961 1 1 0004425 indole-3-glycerol-phosphate synthase activity F 1 1 1 100 100 1 1 1 100 100 0.961 1 1 0006228 UTP biosynthetic process P 1 1 1 100 100 1 1 1 100 100 0.961 1 1 0016226 iron-sulfur cluster assembly P 1 1 3 100 33.33333 1 1 3 100 33.33333 0.961 1 1 0036361 racemase activity, acting on amino acids and derivatives F 0 0 1 0 0 1 1 2 100 50 0.961 1 1 0043772 acyl-phosphate glycerol-3-phosphate acyltransferase activity F 1 1 1 100 100 1 1 1 100 100 0.961 1 1 0006429 leucyl-tRNA aminoacylation P 1 1 1 100 100 1 1 1 100 100 0.961 1 1 0070085 glycosylation P 0 0 0 0 0 1 1 1 100 100 0.961 1 1 0016623 oxidoreductase activity, acting on the aldehyde or oxo group of donors, oxygen as acceptor F 0 0 0 0 0 1 1 1 100 100 0.961 1 1 0004823 leucine-tRNA ligase activity F 1 1 1 100 100 1 1 1 100 100 0.961 1 1 0008728 GTP diphosphokinase activity F 1 1 1 100 100 1 1 1 100 100 0.961 1 1 0004813 alanine-tRNA ligase activity F 1 1 1 100 100 1 1 1 100 100 0.961 1 1 0009078 pyruvate family amino acid metabolic process P 0 0 0 0 0 1 1 1 100 100 0.961 1 1 0016855 racemase and epimerase activity, acting on amino acids and derivatives F 0 0 1 0 0 1 1 2 100 50 0.961 1 1 0006535 cysteine biosynthetic process from serine P 1 1 2 100 50 1 1 2 100 50 0.961 1 1 0006397 mRNA processing P 1 1 1 100 100 1 1 1 100 100 0.961 1 1 0006523 alanine biosynthetic process P 0 0 0 0 0 1 1 1 100 100 0.961 1 1 0006183 GTP biosynthetic process P 1 1 1 100 100 1 1 1 100 100 0.961 1 1 0008479 queuine tRNA-ribosyltransferase activity F 1 1 1 100 100 1 1 1 100 100 0.961 1 1 0042255 ribosome assembly P 0 0 0 0 0 1 1 1 100 100 0.961 1 1 0051248 negative regulation of protein metabolic process P 0 0 0 0 0 1 1 1 100 100 0.961 1 1 0004365 glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity F 1 1 1 100 100 1 1 1 100 100 0.961 1 1 0004345 glucose-6-phosphate dehydrogenase activity F 1 1 1 100 100 1 1 1 100 100 0.961 1 1 0008375 acetylglucosaminyltransferase activity F 0 0 0 0 0 1 1 1 100 100 0.961 1 1 0046437 D-amino acid biosynthetic process P 0 0 0 0 0 1 1 1 100 100 0.961 1 1 0046145 D-alanine family amino acid biosynthetic process P 0 0 0 0 0 1 1 1 100 100 0.961 1 1 0004140 dephospho-CoA kinase activity F 1 1 1 100 100 1 1 1 100 100 0.961 1 1 0006430 lysyl-tRNA aminoacylation P 1 1 1 100 100 1 1 1 100 100 0.961 1 1 0004824 lysine-tRNA ligase activity F 1 1 1 100 100 1 1 1 100 100 0.961 1 1 0004459 L-lactate dehydrogenase activity F 1 1 1 100 100 1 1 1 100 100 0.961 1 1 0045263 proton-transporting ATP synthase complex, coupling factor F(o) C 1 1 3 100 33.33333 1 1 3 100 33.33333 0.961 1 1 0032269 negative regulation of cellular protein metabolic process P 0 0 0 0 0 1 1 1 100 100 0.961 1 1 0046436 D-alanine metabolic process P 0 0 0 0 0 1 1 1 100 100 0.961 1 1 0010138 pyrimidine ribonucleotide salvage P 0 0 0 0 0 1 1 2 100 50 0.961 1 1 0008965 phosphoenolpyruvate-protein phosphotransferase activity F 1 1 1 100 100 1 1 1 100 100 0.961 1 1 0016211 ammonia ligase activity F 0 0 0 0 0 1 1 2 100 50 0.961 1 1 0071941 nitrogen cycle metabolic process P 0 0 0 0 0 1 1 1 100 100 0.961 1 1 0046087 cytidine metabolic process P 0 0 0 0 0 1 1 1 100 100 0.961 1 1 0072529 pyrimidine-containing compound catabolic process P 0 0 0 0 0 1 1 1 100 100 0.961 1 1 0019213 deacetylase activity F 0 0 0 0 0 1 1 2 100 50 0.961 1 1 0046135 pyrimidine nucleoside catabolic process P 0 0 0 0 0 1 1 1 100 100 0.961 1 1 0043604 amide biosynthetic process P 0 0 0 0 0 1 1 3 100 33.33333 0.961 1 1 0030955 potassium ion binding F 1 1 1 100 100 1 1 1 100 100 0.961 1 1 0046133 pyrimidine ribonucleoside catabolic process P 0 0 0 0 0 1 1 1 100 100 0.961 1 1 0046500 S-adenosylmethionine metabolic process P 0 0 0 0 0 1 1 1 100 100 0.961 1 1 0016638 oxidoreductase activity, acting on the CH-NH2 group of donors F 0 0 0 0 0 1 1 1 100 100 0.961 1 1 0031163 metallo-sulfur cluster assembly P 0 0 0 0 0 1 1 3 100 33.33333 0.961 1 1 0051998 protein carboxyl O-methyltransferase activity F 0 0 0 0 0 1 1 1 100 100 0.961 1 1 0004743 pyruvate kinase activity F 1 1 1 100 100 1 1 1 100 100 0.961 1 1 0043543 protein acylation P 0 0 0 0 0 1 1 1 100 100 0.961 1 1 0006402 mRNA catabolic process P 1 1 2 100 50 1 1 2 100 50 0.961 1 1 0006216 cytidine catabolic process P 0 0 0 0 0 1 1 1 100 100 0.961 1 1 0004060 arylamine N-acetyltransferase activity F 1 1 1 100 100 1 1 1 100 100 0.961 1 1 0019239 deaminase activity F 0 0 1 0 0 1 1 4 100 25 0.961 1 1 0004654 polyribonucleotide nucleotidyltransferase activity F 1 1 1 100 100 1 1 1 100 100 0.961 1 1 0016882 cyclo-ligase activity F 0 0 0 0 0 1 1 2 100 50 0.961 1 1 0070043 rRNA (guanine-N7-)-methyltransferase activity F 1 1 1 100 100 1 1 1 100 100 0.961 1 1 0070476 rRNA (guanine-N7)-methylation P 1 1 1 100 100 1 1 1 100 100 0.961 1 1 0003713 transcription coactivator activity F 1 1 1 100 100 1 1 1 100 100 0.961 1 1 0034661 ncRNA catabolic process P 0 0 0 0 0 1 1 1 100 100 0.961 1 1 0000989 transcription factor binding transcription factor activity F 0 0 0 0 0 1 1 1 100 100 0.961 1 1 0043043 peptide biosynthetic process P 0 0 1 0 0 1 1 2 100 50 0.961 1 1 0044092 negative regulation of molecular function P 0 0 0 0 0 1 1 1 100 100 0.961 1 1 0017000 antibiotic biosynthetic process P 0 0 0 0 0 1 1 1 100 100 0.961 1 1 0016999 antibiotic metabolic process P 0 0 0 0 0 1 1 1 100 100 0.961 1 1 0008235 metalloexopeptidase activity F 0 0 1 0 0 1 1 2 100 50 0.961 1 1 0006518 peptide metabolic process P 0 0 1 0 0 1 1 4 100 25 0.961 1 1 0045982 negative regulation of purine nucleobase metabolic process P 1 1 1 100 100 1 1 1 100 100 0.961 1 1 0030650 peptide antibiotic metabolic process P 0 0 0 0 0 1 1 1 100 100 0.961 1 1 0046224 bacteriocin metabolic process P 0 0 0 0 0 1 1 1 100 100 0.961 1 1 0004523 ribonuclease H activity F 1 1 2 100 50 1 1 2 100 50 0.961 1 1 0009041 uridylate kinase activity F 1 1 1 100 100 1 1 1 100 100 0.961 1 1 0004176 ATP-dependent peptidase activity F 1 1 1 100 100 1 1 1 100 100 0.961 1 1 0017144 drug metabolic process P 0 0 0 0 0 1 1 1 100 100 0.961 1 1 0016420 malonyltransferase activity F 0 0 0 0 0 1 1 1 100 100 0.961 1 1 0016419 S-malonyltransferase activity F 0 0 0 0 0 1 1 1 100 100 0.961 1 1 0032262 pyrimidine nucleotide salvage P 0 0 0 0 0 1 1 2 100 50 0.961 1 1 0043603 cellular amide metabolic process P 0 0 0 0 0 1 1 5 100 20 0.961 1 1 0009445 putrescine metabolic process P 0 0 0 0 0 1 1 1 100 100 0.961 1 1 0046051 UTP metabolic process P 0 0 0 0 0 1 1 1 100 100 0.961 1 1 0010340 carboxyl-O-methyltransferase activity F 0 0 0 0 0 1 1 1 100 100 0.961 1 1 0006449 regulation of translational termination P 1 1 1 100 100 1 1 1 100 100 0.961 1 1 0018410 C-terminal protein amino acid modification P 0 0 0 0 0 1 1 1 100 100 0.961 1 1 0032506 cytokinetic process P 0 0 0 0 0 1 1 6 100 16.66667 0.961 1 1 0016790 thiolester hydrolase activity F 1 1 1 100 100 1 1 1 100 100 0.961 1 1 0090529 cell septum assembly P 0 0 0 0 0 1 1 6 100 16.66667 0.961 1 1 0018065 protein-cofactor linkage P 0 0 0 0 0 1 1 2 100 50 0.961 1 1 0042157 lipoprotein metabolic process P 0 0 0 0 0 1 1 1 100 100 0.961 1 1 0043733 DNA-3-methylbase glycosylase activity F 0 0 0 0 0 1 1 1 100 100 0.961 1 1 0003905 alkylbase DNA N-glycosylase activity F 0 0 0 0 0 1 1 1 100 100 0.961 1 1 0033862 UMP kinase activity F 1 1 1 100 100 1 1 1 100 100 0.961 1 1 0003880 protein C-terminal carboxyl O-methyltransferase activity F 0 0 0 0 0 1 1 1 100 100 0.961 1 1 0043687 post-translational protein modification P 0 0 0 0 0 1 1 1 100 100 0.961 1 1 0006543 glutamine catabolic process P 1 1 2 100 50 1 1 2 100 50 0.961 1 1 0000175 3’-5’-exoribonuclease activity F 1 1 1 100 100 1 1 1 100 100 0.961 1 1 0030651 peptide antibiotic biosynthetic process P 0 0 0 0 0 1 1 1 100 100 0.961 1 1 0004496 mevalonate kinase activity F 1 1 1 100 100 1 1 1 100 100 0.961 1 1 0008763 UDP-N-acetylmuramate-L-alanine ligase activity F 1 1 1 100 100 1 1 1 100 100 0.961 1 1 0046341 CDP-diacylglycerol metabolic process P 0 0 0 0 0 1 1 1 100 100 0.961 1 1 0004163 diphosphomevalonate decarboxylase activity F 1 1 1 100 100 1 1 1 100 100 0.961 1 1 0019321 pentose metabolic process P 0 0 0 0 0 1 1 1 100 100 0.961 1 1 0051748 UTP-monosaccharide-1-phosphate uridylyltransferase activity F 0 0 0 0 0 1 1 1 100 100 0.961 1 1 0009001 serine O-acetyltransferase activity F 1 1 1 100 100 1 1 1 100 100 0.961 1 1 0071804 cellular potassium ion transport P 0 0 0 0 0 1 1 2 100 50 0.961 1 1 0003952 NAD+ synthase (glutamine-hydrolyzing) activity F 1 1 1 100 100 1 1 1 100 100 0.961 1 1 0008795 NAD+ synthase activity F 1 1 1 100 100 1 1 1 100 100 0.961 1 1 0009628 response to abiotic stimulus P 0 0 0 0 0 1 1 1 100 100 0.961 1 1 0090071 negative regulation of ribosome biogenesis P 1 1 1 100 100 1 1 1 100 100 0.961 1 1 0047112 pyruvate oxidase activity F 1 1 1 100 100 1 1 1 100 100 0.961 1 1 0030894 replisome C 0 0 0 0 0 1 1 1 100 100 0.961 1 1 0019276 UDP-N-acetylgalactosamine metabolic process P 0 0 0 0 0 1 1 3 100 33.33333 0.961 1 1 0016886 ligase activity, forming phosphoric ester bonds F 0 0 0 0 0 1 1 1 100 100 0.961 1 1 0055072 iron ion homeostasis P 0 0 0 0 0 1 1 1 100 100 0.961 1 1 0016842 amidine-lyase activity F 0 0 0 0 0 1 1 1 100 100 0.961 1 1 0009266 response to temperature stimulus P 0 0 0 0 0 1 1 1 100 100 0.961 1 1 0055076 transition metal ion homeostasis P 0 0 0 0 0 1 1 2 100 50 0.961 1 1 0004109 coproporphyrinogen oxidase activity F 1 1 1 100 100 1 1 1 100 100 0.961 1 1 0000702 oxidized base lesion DNA N-glycosylase activity F 0 0 0 0 0 1 1 1 100 100 0.961 1 1 0003909 DNA ligase activity F 0 0 0 0 0 1 1 1 100 100 0.961 1 1 0019430 removal of superoxide radicals P 1 1 1 100 100 1 1 1 100 100 0.961 1 1 0004791 thioredoxin-disulfide reductase activity F 1 1 1 100 100 1 1 1 100 100 0.961 1 1 0044462 external encapsulating structure part C 0 0 0 0 0 1 1 2 100 50 0.961 1 1 0042256 mature ribosome assembly P 1 1 1 100 100 1 1 1 100 100 0.961 1 1 0004595 pantetheine-phosphate adenylyltransferase activity F 1 1 1 100 100 1 1 1 100 100 0.961 1 1 0016208 AMP binding F 1 1 1 100 100 1 1 1 100 100 0.961 1 1 0034227 tRNA thio-modification P 1 1 1 100 100 1 1 1 100 100 0.961 1 1 0003712 transcription cofactor activity F 0 0 0 0 0 1 1 1 100 100 0.961 1 1 0019520 aldonic acid metabolic process P 0 0 0 0 0 1 1 1 100 100 0.961 1 1 0043590 bacterial nucleoid C 1 1 1 100 100 1 1 1 100 100 0.961 1 1 0015151 alpha-glucoside transmembrane transporter activity F 0 0 0 0 0 1 1 1 100 100 0.961 1 1 0004457 lactate dehydrogenase activity F 0 0 0 0 0 1 1 1 100 100 0.961 1 1 0030696 tRNA (m5U54) methyltransferase activity F 0 0 0 0 0 1 1 1 100 100 0.961 1 1 0016300 tRNA (uracil) methyltransferase activity F 0 0 0 0 0 1 1 1 100 100 0.961 1 1 1901998 toxin transport P 0 0 0 0 0 1 1 1 100 100 0.961 1 1 0016435 rRNA (guanine) methyltransferase activity F 0 0 0 0 0 1 1 1 100 100 0.961 1 1 0042947 glucoside transmembrane transporter activity F 0 0 0 0 0 1 1 1 100 100 0.961 1 1 0042602 riboflavin reductase (NADPH) activity F 1 1 1 100 100 1 1 1 100 100 0.961 1 1 0019136 deoxynucleoside kinase activity F 0 0 0 0 0 1 1 1 100 100 0.961 1 1 0019856 pyrimidine nucleobase biosynthetic process P 0 0 0 0 0 1 1 5 100 20 0.961 1 1 0008169 C-methyltransferase activity F 0 0 0 0 0 1 1 1 100 100 0.961 1 1 0017148 negative regulation of translation P 1 1 1 100 100 1 1 1 100 100 0.961 1 1 0016635 oxidoreductase activity, acting on the CH-CH group of donors, quinone or related compound as acceptor F 0 0 0 0 0 1 1 2 100 50 0.961 1 1 0055065 metal ion homeostasis P 0 0 0 0 0 1 1 2 100 50 0.961 1 1 0015417 polyamine-transporting ATPase activity F 1 1 1 100 100 1 1 1 100 100 0.961 1 1 0015594 putrescine-importing ATPase activity F 1 1 1 100 100 1 1 1 100 100 0.961 1 1 0007062 sister chromatid cohesion P 1 1 1 100 100 1 1 1 100 100 0.961 1 1 0015595 spermidine-importing ATPase activity F 1 1 1 100 100 1 1 1 100 100 0.961 1 1 0015079 potassium ion transmembrane transporter activity F 0 0 1 0 0 1 1 2 100 50 0.961 1 1 0015542 sugar efflux transmembrane transporter activity F 1 1 1 100 100 1 1 1 100 100 0.961 1 1 0006859 extracellular carbohydrate transport P 1 1 1 100 100 1 1 1 100 100 0.961 1 1 0016426 tRNA (adenine) methyltransferase activity F 0 0 0 0 0 1 1 2 100 50 0.961 1 1 0006858 extracellular transport P 0 0 0 0 0 1 1 1 100 100 0.961 1 1 0004845 uracil phosphoribosyltransferase activity F 1 1 2 100 50 1 1 2 100 50 0.961 1 1 0047482 UDP-N-acetylmuramoyl-L-alanyl-D-glutamate-L-lysine ligase activity F 1 1 1 100 100 1 1 1 100 100 0.961 1 1 0055080 cation homeostasis P 0 0 0 0 0 1 1 2 100 50 0.961 1 1 0000302 response to reactive oxygen species P 0 0 0 0 0 1 1 1 100 100 0.961 1 1 0051668 localization within membrane P 0 0 0 0 0 1 1 2 100 50 0.961 1 1 0052381 tRNA dimethylallyltransferase activity F 1 1 1 100 100 1 1 1 100 100 0.961 1 1 0015803 branched-chain amino acid transport P 1 1 1 100 100 1 1 1 100 100 0.961 1 1 0015658 branched-chain amino acid transmembrane transporter activity F 1 1 1 100 100 1 1 1 100 100 0.961 1 1 0033817 beta-ketoacyl-acyl-carrier-protein synthase II activity F 1 1 1 100 100 1 1 1 100 100 0.961 1 1 0004750 ribulose-phosphate 3-epimerase activity F 1 1 1 100 100 1 1 1 100 100 0.961 1 1 0009972 cytidine deamination P 1 1 1 100 100 1 1 1 100 100 0.961 1 1 0004126 cytidine deaminase activity F 1 1 1 100 100 1 1 1 100 100 0.961 1 1 0008655 pyrimidine-containing compound salvage P 1 1 2 100 50 1 1 2 100 50 0.961 1 1 0043896 glucan 1,6-alpha-glucosidase activity F 1 1 1 100 100 1 1 1 100 100 0.961 1 1 0044206 UMP salvage P 1 1 2 100 50 1 1 2 100 50 0.961 1 1 1901700 response to oxygen-containing compound P 0 0 0 0 0 1 1 1 100 100 0.961 1 1 0000303 response to superoxide P 0 0 0 0 0 1 1 1 100 100 0.961 1 1 0006268 DNA unwinding involved in DNA replication P 1 1 1 100 100 1 1 1 100 100 0.961 1 1 0035821 modification of morphology or physiology of other organism P 0 0 0 0 0 1 1 1 100 100 0.961 1 1 0001906 cell killing P 0 0 0 0 0 1 1 1 100 100 0.961 1 1 0004360 glutamine-fructose-6-phosphate transaminase (isomerizing) activity F 1 1 1 100 100 1 1 1 100 100 0.961 1 1 0004638 phosphoribosylaminoimidazole carboxylase activity F 1 1 1 100 100 1 1 1 100 100 0.961 1 1 0047200 tetrahydrodipicolinate N-acetyltransferase activity F 1 1 1 100 100 1 1 1 100 100 0.961 1 1 0006979 response to oxidative stress P 0 0 1 0 0 1 1 2 100 50 0.961 1 1 0004765 shikimate kinase activity F 1 1 1 100 100 1 1 1 100 100 0.961 1 1 0019134 glucosamine-1-phosphate N-acetyltransferase activity F 1 1 1 100 100 1 1 1 100 100 0.961 1 1 0006048 UDP-N-acetylglucosamine biosynthetic process P 1 1 1 100 100 1 1 1 100 100 0.961 1 1 0003977 UDP-N-acetylglucosamine diphosphorylase activity F 1 1 1 100 100 1 1 1 100 100 0.961 1 1 0018995 host C 0 0 0 0 0 1 1 1 100 100 0.961 1 1 0051715 cytolysis in other organism P 0 0 0 0 0 1 1 1 100 100 0.961 1 1 0006011 UDP-glucose metabolic process P 1 1 1 100 100 1 1 1 100 100 0.961 1 1 0003983 UTP:glucose-1-phosphate uridylyltransferase activity F 1 1 1 100 100 1 1 1 100 100 0.961 1 1 0031640 killing of cells of other organism P 0 0 0 0 0 1 1 1 100 100 0.961 1 1 0004849 uridine kinase activity F 1 1 1 100 100 1 1 1 100 100 0.961 1 1 0000917 barrier septum assembly P 1 1 6 100 16.66667 1 1 6 100 16.66667 0.961 1 1 0003911 DNA ligase (NAD+) activity F 1 1 1 100 100 1 1 1 100 100 0.961 1 1 0016812 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides F 1 1 1 100 100 1 1 1 100 100 0.961 1 1 0004151 dihydroorotase activity F 1 1 1 100 100 1 1 1 100 100 0.961 1 1 0008725 DNA-3-methyladenine glycosylase activity F 1 1 1 100 100 1 1 1 100 100 0.961 1 1 0003938 IMP dehydrogenase activity F 1 1 1 100 100 1 1 1 100 100 0.961 1 1 0044364 disruption of cells of other organism P 0 0 0 0 0 1 1 1 100 100 0.961 1 1 0006481 C-terminal protein methylation P 1 1 1 100 100 1 1 1 100 100 0.961 1 1 0004671 protein C-terminal S-isoprenylcysteine carboxyl O-methyltransferase activity F 1 1 1 100 100 1 1 1 100 100 0.961 1 1 0044211 CTP salvage P 1 1 1 100 100 1 1 1 100 100 0.961 1 1 0051258 protein polymerization P 1 1 1 100 100 1 1 1 100 100 0.961 1 1 0034614 cellular response to reactive oxygen species P 0 0 0 0 0 1 1 1 100 100 0.961 1 1 0004807 triose-phosphate isomerase activity F 1 1 1 100 100 1 1 1 100 100 0.961 1 1 1901701 cellular response to oxygen-containing compound P 0 0 0 0 0 1 1 1 100 100 0.961 1 1 0047952 glycerol-3-phosphate dehydrogenase [NAD(P)+] activity F 1 1 1 100 100 1 1 1 100 100 0.961 1 1 0046168 glycerol-3-phosphate catabolic process P 1 1 1 100 100 1 1 1 100 100 0.961 1 1 0046167 glycerol-3-phosphate biosynthetic process P 1 1 1 100 100 1 1 1 100 100 0.961 1 1 0036439 glycerol-3-phosphate dehydrogenase [NADP+] activity F 1 1 1 100 100 1 1 1 100 100 0.961 1 1 0004367 glycerol-3-phosphate dehydrogenase [NAD+] activity F 1 1 1 100 100 1 1 1 100 100 0.961 1 1 0042726 flavin-containing compound metabolic process P 0 0 0 0 0 1 1 5 100 20 0.961 1 1 0018904 ether metabolic process P 0 0 0 0 0 1 1 2 100 50 0.961 1 1 0006474 N-terminal protein amino acid acetylation P 1 1 1 100 100 1 1 1 100 100 0.961 1 1 0042727 flavin-containing compound biosynthetic process P 0 0 0 0 0 1 1 5 100 20 0.961 1 1 0071451 cellular response to superoxide P 0 0 0 0 0 1 1 1 100 100 0.961 1 1 0047605 acetolactate decarboxylase activity F 1 1 1 100 100 1 1 1 100 100 0.961 1 1 0051991 UDP-N-acetyl-D-glucosamine:N-acetylmuramoyl-L-alanyl-D-glutamyl-meso-2,6-diaminopimelyl-D-alanyl-D-alanine-diphosphoundecaprenol 4-beta-N-acetylglucosaminlytransferase activity F 1 1 1 100 100 1 1 1 100 100 0.961 1 1 0050511 undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase activity F 1 1 1 100 100 1 1 1 100 100 0.961 1 1 0030259 lipid glycosylation P 1 1 1 100 100 1 1 1 100 100 0.961 1 1 0019277 UDP-N-acetylgalactosamine biosynthetic process P 1 1 3 100 33.33333 1 1 3 100 33.33333 0.961 1 1 0006771 riboflavin metabolic process P 0 0 0 0 0 1 1 5 100 20 0.961 1 1 0004371 glycerone kinase activity F 1 1 1 100 100 1 1 1 100 100 0.961 1 1 0046073 dTMP metabolic process P 0 0 0 0 0 1 1 1 100 100 0.961 1 1 0009177 pyrimidine deoxyribonucleoside monophosphate biosynthetic process P 0 0 0 0 0 1 1 1 100 100 0.961 1 1 0009176 pyrimidine deoxyribonucleoside monophosphate metabolic process P 0 0 0 0 0 1 1 1 100 100 0.961 1 1 0046656 folic acid biosynthetic process P 1 1 2 100 50 1 1 2 100 50 0.961 1 1 0004156 dihydropteroate synthase activity F 1 1 1 100 100 1 1 1 100 100 0.961 1 1 0022836 gated channel activity F 0 0 0 0 0 1 1 1 100 100 0.961 1 1 0072593 reactive oxygen species metabolic process P 0 0 0 0 0 1 1 2 100 50 0.961 1 1 0006801 superoxide metabolic process P 0 0 1 0 0 1 1 2 100 50 0.961 1 1 0034599 cellular response to oxidative stress P 0 0 0 0 0 1 1 1 100 100 0.961 1 1 0004614 phosphoglucomutase activity F 1 1 1 100 100 1 1 1 100 100 0.961 1 1 0004356 glutamate-ammonia ligase activity F 1 1 1 100 100 1 1 1 100 100 0.961 1 1 0070887 cellular response to chemical stimulus P 0 0 0 0 0 1 1 1 100 100 0.961 1 1 0006542 glutamine biosynthetic process P 1 1 1 100 100 1 1 1 100 100 0.961 1 1 0009221 pyrimidine deoxyribonucleotide biosynthetic process P 0 0 0 0 0 1 1 2 100 50 0.961 1 1 0006556 S-adenosylmethionine biosynthetic process P 1 1 1 100 100 1 1 1 100 100 0.961 1 1 0004478 methionine adenosyltransferase activity F 1 1 1 100 100 1 1 1 100 100 0.961 1 1 0008853 exodeoxyribonuclease III activity F 1 1 1 100 100 1 1 1 100 100 0.961 1 1 0016867 intramolecular transferase activity, transferring acyl groups F 0 0 0 0 0 1 1 1 100 100 0.961 1 1 0004069 L-aspartate:2-oxoglutarate aminotransferase activity F 1 1 1 100 100 1 1 1 100 100 0.961 1 1 0004347 glucose-6-phosphate isomerase activity F 1 1 1 100 100 1 1 1 100 100 0.961 1 1 0009399 nitrogen fixation P 1 1 1 100 100 1 1 1 100 100 0.961 1 1 0009157 deoxyribonucleoside monophosphate biosynthetic process P 0 0 0 0 0 1 1 1 100 100 0.961 1 1 0022832 voltage-gated channel activity F 0 0 0 0 0 1 1 1 100 100 0.961 1 1 0008839 4-hydroxy-tetrahydrodipicolinate reductase F 1 1 1 100 100 1 1 1 100 100 0.961 1 1 0003725 double-stranded RNA binding F 1 1 1 100 100 1 1 1 100 100 0.961 1 1 0052888 dihydroorotate oxidase (fumarate) activity F 1 1 1 100 100 1 1 1 100 100 0.961 1 1 0006207 ’de novo’ pyrimidine nucleobase biosynthetic process P 1 1 5 100 20 1 1 5 100 20 0.961 1 1 0004158 dihydroorotate oxidase activity F 1 1 2 100 50 1 1 2 100 50 0.961 1 1 0004152 dihydroorotate dehydrogenase activity F 1 1 2 100 50 1 1 2 100 50 0.961 1 1 0004088 carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity F 1 1 2 100 50 1 1 2 100 50 0.961 1 1 0071805 potassium ion transmembrane transport P 1 1 2 100 50 1 1 2 100 50 0.961 1 1 0022820 potassium ion symporter activity F 1 1 1 100 100 1 1 1 100 100 0.961 1 1 0004350 glutamate-5-semialdehyde dehydrogenase activity F 1 1 1 100 100 1 1 1 100 100 0.961 1 1 0016726 oxidoreductase activity, acting on CH or CH2 groups, NAD or NADP as acceptor F 1 1 1 100 100 1 1 1 100 100 0.961 1 1 0009019 tRNA (guanine-N1-)-methyltransferase activity F 1 1 1 100 100 1 1 1 100 100 0.961 1 1 0006141 regulation of purine nucleobase metabolic process P 0 0 0 0 0 1 1 1 100 100 0.961 1 1 0004329 formate-tetrahydrofolate ligase activity F 1 1 1 100 100 1 1 1 100 100 0.961 1 1 0044341 sodium-dependent phosphate transport P 1 1 1 100 100 1 1 1 100 100 0.961 1 1 0015321 sodium-dependent phosphate transmembrane transporter activity F 1 1 1 100 100 1 1 1 100 100 0.961 1 1 0004476 mannose-6-phosphate isomerase activity F 1 1 1 100 100 1 1 1 100 100 0.961 1 1 0008308 voltage-gated anion channel activity F 0 0 0 0 0 1 1 1 100 100 0.961 1 1 0003866 3-phosphoshikimate 1-carboxyvinyltransferase activity F 1 1 1 100 100 1 1 1 100 100 0.961 1 1 0004324 ferredoxin-NADP+ reductase activity F 1 1 1 100 100 1 1 1 100 100 0.961 1 1 0070402 NADPH binding F 1 1 1 100 100 1 1 1 100 100 0.961 1 1 0051992 UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-meso-2,6-diaminopimelyl-D-alanyl-D-alanine:undecaprenyl-phosphate transferase activity F 1 1 1 100 100 1 1 1 100 100 0.961 1 1 0015108 chloride transmembrane transporter activity F 0 0 0 0 0 1 1 1 100 100 0.961 1 1 0033643 host cell part C 0 0 0 0 0 1 1 1 100 100 0.961 1 1 0043657 host cell C 0 0 0 0 0 1 1 1 100 100 0.961 1 1 0044216 other organism cell C 0 0 0 0 0 1 1 1 100 100 0.961 1 1 0044217 other organism part C 0 0 0 0 0 1 1 1 100 100 0.961 1 1 0044215 other organism C 0 0 0 0 0 1 1 1 100 100 0.961 1 1 0022839 ion gated channel activity F 0 0 0 0 0 1 1 1 100 100 0.961 1 1 0005244 voltage-gated ion channel activity F 0 0 0 0 0 1 1 1 100 100 0.961 1 1 0004605 phosphatidate cytidylyltransferase activity F 1 1 1 100 100 1 1 1 100 100 0.961 1 1 0005254 chloride channel activity F 0 0 0 0 0 1 1 1 100 100 0.961 1 1 0016024 CDP-diacylglycerol biosynthetic process P 1 1 1 100 100 1 1 1 100 100 0.961 1 1 0008963 phospho-N-acetylmuramoyl-pentapeptide-transferase activity F 1 1 1 100 100 1 1 1 100 100 0.961 1 1 0003941 L-serine ammonia-lyase activity F 1 1 2 100 50 1 1 2 100 50 0.961 1 1 0070626 (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamido)succinate AMP-lyase (fumarate-forming) activity F 1 1 1 100 100 1 1 1 100 100 0.961 1 1 0005253 anion channel activity F 0 0 0 0 0 1 1 1 100 100 0.961 1 1 0004018 N6-(1,2-dicarboxyethyl)AMP AMP-lyase (fumarate-forming) activity F 1 1 1 100 100 1 1 1 100 100 0.961 1 1 0009052 pentose-phosphate shunt, non-oxidative branch P 1 1 1 100 100 1 1 1 100 100 0.961 1 1 0004751 ribose-5-phosphate isomerase activity F 1 1 1 100 100 1 1 1 100 100 0.961 1 1 0052906 tRNA (guanine(37)-N(1))-methyltransferase activity F 1 1 1 100 100 1 1 1 100 100 0.961 1 1 0008836 diaminopimelate decarboxylase activity F 1 1 1 100 100 1 1 1 100 100 0.961 1 1 1990077 primosome complex C 1 1 1 100 100 1 1 1 100 100 0.961 1 1 0030152 bacteriocin biosynthetic process P 1 1 1 100 100 1 1 1 100 100 0.961 1 1 0046075 dTTP metabolic process P 0 0 0 0 0 1 1 2 100 50 0.961 1 1 0006427 histidyl-tRNA aminoacylation P 1 1 1 100 100 1 1 1 100 100 0.961 1 1 0004821 histidine-tRNA ligase activity F 1 1 1 100 100 1 1 1 100 100 0.961 1 1 0046385 deoxyribose phosphate biosynthetic process P 0 0 0 0 0 1 1 2 100 50 0.961 1 1 0006438 valyl-tRNA aminoacylation P 1 1 1 100 100 1 1 1 100 100 0.961 1 1 0004832 valine-tRNA ligase activity F 1 1 1 100 100 1 1 1 100 100 0.961 1 1 0004089 carbonate dehydratase activity F 1 1 1 100 100 1 1 1 100 100 0.961 1 1 0044279 other organism membrane C 0 0 0 0 0 1 1 1 100 100 0.961 1 1 0008998 ribonucleoside-triphosphate reductase activity F 1 1 1 100 100 1 1 1 100 100 0.961 1 1 0004825 methionine-tRNA ligase activity F 1 1 1 100 100 1 1 1 100 100 0.961 1 1 0044218 other organism cell membrane C 0 0 0 0 0 1 1 1 100 100 0.961 1 1 0004659 prenyltransferase activity F 1 1 1 100 100 1 1 2 100 50 0.961 1 1 0016639 oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor F 1 1 1 100 100 1 1 1 100 100 0.961 1 1 0036009 protein-glutamine N-methyltransferase activity F 1 1 1 100 100 1 1 1 100 100 0.961 1 1 0018364 peptidyl-glutamine methylation P 1 1 1 100 100 1 1 1 100 100 0.961 1 1 0048038 quinone binding F 1 1 1 100 100 1 1 1 100 100 0.961 1 1 0005507 copper ion binding F 1 1 2 100 50 1 1 2 100 50 0.961 1 1 0009162 deoxyribonucleoside monophosphate metabolic process P 0 0 0 0 0 1 1 1 100 100 0.961 1 1 0004731 purine-nucleoside phosphorylase activity F 1 1 2 100 50 1 1 2 100 50 0.961 1 1 0006431 methionyl-tRNA aminoacylation P 1 1 1 100 100 1 1 1 100 100 0.961 1 1 0042586 peptide deformylase activity F 1 1 2 100 50 1 1 2 100 50 0.961 1 1 0042891 antibiotic transport P 1 1 1 100 100 1 1 1 100 100 0.961 1 1 0006436 tryptophanyl-tRNA aminoacylation P 1 1 1 100 100 1 1 1 100 100 0.961 1 1 0004830 tryptophan-tRNA ligase activity F 1 1 1 100 100 1 1 1 100 100 0.961 1 1 0047151 methylenetetrahydrofolate-tRNA-(uracil-5-)-methyltransferase (FADH2-oxidizing) activity F 1 1 1 100 100 1 1 1 100 100 0.961 1 1 0030698 5,10-methylenetetrahydrofolate-dependent tRNA (m5U54) methyltransferase activity F 1 1 1 100 100 1 1 1 100 100 0.961 1 1 0043245 extraorganismal space C 0 0 0 0 0 1 1 1 100 100 0.961 1 1 0006570 tyrosine metabolic process P 0 0 0 0 0 1 1 1 100 100 0.961 1 1 0009095 aromatic amino acid family biosynthetic process, prephenate pathway P 0 0 0 0 0 1 1 2 100 50 0.961 1 1 0009212 pyrimidine deoxyribonucleoside triphosphate biosynthetic process P 0 0 0 0 0 1 1 2 100 50 0.961 1 1 0036370 D-alanyl carrier activity F 1 1 1 100 100 1 1 1 100 100 0.961 1 1 0043244 regulation of protein complex disassembly P 0 0 0 0 0 1 1 3 100 33.33333 0.961 1 1 0047451 3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity F 1 1 1 100 100 1 1 1 100 100 0.961 1 1 0019171 3-hydroxyacyl-[acyl-carrier-protein] dehydratase activity F 1 1 1 100 100 1 1 1 100 100 0.961 1 1 0006002 fructose 6-phosphate metabolic process P 1 1 1 100 100 1 1 1 100 100 0.961 1 1 0005945 6-phosphofructokinase complex C 1 1 1 100 100 1 1 1 100 100 0.961 1 1 0003872 6-phosphofructokinase activity F 1 1 1 100 100 1 1 1 100 100 0.961 1 1 0008443 phosphofructokinase activity F 1 1 1 100 100 1 1 2 100 50 0.961 1 1 0009202 deoxyribonucleoside triphosphate biosynthetic process P 0 0 0 0 0 1 1 2 100 50 0.961 1 1 0044421 extracellular region part C 0 0 0 0 0 1 1 1 100 100 0.961 1 1 0009265 2’-deoxyribonucleotide biosynthetic process P 0 0 0 0 0 1 1 2 100 50 0.961 1 1 0070400 teichoic acid D-alanylation P 1 1 1 100 100 1 1 1 100 100 0.961 1 1 0005786 signal recognition particle, endoplasmic reticulum targeting C 1 1 1 100 100 1 1 1 100 100 0.961 1 1 0044208 ’de novo’ AMP biosynthetic process P 1 1 1 100 100 1 1 1 100 100 0.961 1 1 0004619 phosphoglycerate mutase activity F 1 1 2 100 50 1 1 2 100 50 0.961 1 1 0048500 signal recognition particle C 1 1 1 100 100 1 1 1 100 100 0.961 1 1 0006231 dTMP biosynthetic process P 1 1 1 100 100 1 1 1 100 100 0.961 1 1 0090069 regulation of ribosome biogenesis P 0 0 0 0 0 1 1 1 100 100 0.961 1 1 0004497 monooxygenase activity F 0 0 0 0 0 1 1 1 100 100 0.961 1 1 0008312 7S RNA binding F 1 1 1 100 100 1 1 1 100 100 0.961 1 1 0008793 aromatic-amino-acid:2-oxoglutarate aminotransferase activity F 1 1 1 100 100 1 1 1 100 100 0.961 1 1 0008176 tRNA (guanine-N7-)-methyltransferase activity F 1 1 1 100 100 1 1 1 100 100 0.961 1 1 0004797 thymidine kinase activity F 1 1 1 100 100 1 1 1 100 100 0.961 1 1 0004160 dihydroxy-acid dehydratase activity F 1 1 1 100 100 1 1 1 100 100 0.961 1 1 0006655 phosphatidylglycerol biosynthetic process P 0 0 0 0 0 1 1 1 100 100 0.961 1 1 0070040 rRNA (adenine-C2-)-methyltransferase activity F 1 1 1 100 100 1 1 1 100 100 0.961 1 1 0047429 nucleoside-triphosphate diphosphatase activity F 1 1 1 100 100 1 1 2 100 50 0.961 1 1 0009986 cell surface C 1 1 3 100 33.33333 1 1 3 100 33.33333 0.961 1 1 0015606 spermidine transmembrane transporter activity F 0 0 0 0 0 1 1 1 100 100 0.961 1 1 0004516 nicotinate phosphoribosyltransferase activity F 1 1 1 100 100 1 1 1 100 100 0.961 1 1 0004019 adenylosuccinate synthase activity F 1 1 1 100 100 1 1 1 100 100 0.961 1 1 0019358 nicotinate nucleotide salvage P 1 1 1 100 100 1 1 1 100 100 0.961 1 1 0046497 nicotinate nucleotide metabolic process P 0 0 0 0 0 1 1 1 100 100 0.961 1 1 0070180 LSU rRNA binding F 1 1 2 100 50 1 1 2 100 50 0.961 1 1 0004799 thymidylate synthase activity F 1 1 1 100 100 1 1 1 100 100 0.961 1 1 0015101 organic cation transmembrane transporter activity F 0 0 0 0 0 1 1 1 100 100 0.961 1 1 0002935 tRNA (adenine-C2-)-methyltransferase activity F 1 1 1 100 100 1 1 1 100 100 0.961 1 1 0034023 5-(carboxyamino)imidazole ribonucleotide mutase activity F 1 1 1 100 100 1 1 1 100 100 0.961 1 1 0050118 N-acetyldiaminopimelate deacetylase activity F 1 1 1 100 100 1 1 1 100 100 0.961 1 1 0004318 enoyl-[acyl-carrier-protein] reductase (NADH) activity F 1 1 1 100 100 1 1 1 100 100 0.961 1 1 0018580 nitronate monooxygenase activity F 1 1 1 100 100 1 1 1 100 100 0.961 1 1 0071826 ribonucleoprotein complex subunit organization P 0 0 0 0 0 1 1 1 100 100 0.961 1 1 0016701 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen F 0 0 0 0 0 1 1 1 100 100 0.961 1 1 0015489 putrescine transmembrane transporter activity F 0 0 0 0 0 1 1 1 100 100 0.961 1 1 0030572 phosphatidyltransferase activity F 0 0 0 0 0 1 1 1 100 100 0.961 1 1 0016413 O-acetyltransferase activity F 0 0 0 0 0 1 1 1 100 100 0.961 1 1 0017150 tRNA dihydrouridine synthase activity F 1 1 1 100 100 1 1 1 100 100 0.961 1 1 0009186 deoxyribonucleoside diphosphate metabolic process P 1 1 1 100 100 1 1 2 100 50 0.961 1 1 0005971 ribonucleoside-diphosphate reductase complex C 1 1 2 100 50 1 1 2 100 50 0.961 1 1 0006534 cysteine metabolic process P 0 0 1 0 0 1 1 3 100 33.33333 0.961 1 1 0003856 3-dehydroquinate synthase activity F 1 1 1 100 100 1 1 1 100 100 0.961 1 1 0009069 serine family amino acid metabolic process P 0 0 0 0 0 1 1 7 100 14.28571 0.961 1 1 0008374 O-acyltransferase activity F 0 0 0 0 0 1 1 2 100 50 0.961 1 1 0051205 protein insertion into membrane P 1 1 2 100 50 1 1 2 100 50 0.961 1 1 0031420 alkali metal ion binding F 0 0 0 0 0 1 1 1 100 100 0.961 1 1 0000906 6,7-dimethyl-8-ribityllumazine synthase activity F 1 1 1 100 100 1 1 1 100 100 0.961 1 1 0006563 L-serine metabolic process P 0 0 1 0 0 1 1 3 100 33.33333 0.961 1 1 0009349 riboflavin synthase complex C 1 1 1 100 100 1 1 1 100 100 0.961 1 1 0009231 riboflavin biosynthetic process P 1 1 5 100 20 1 1 5 100 20 0.961 1 1 0004748 ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor F 1 1 2 100 50 1 1 2 100 50 0.961 1 1 0016703 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of one atom of oxygen (internal monooxygenases or internal mixed function oxidases) F 0 0 0 0 0 1 1 1 100 100 0.961 1 1 0006235 dTTP biosynthetic process P 1 1 2 100 50 1 1 2 100 50 0.961 1 1 0006424 glutamyl-tRNA aminoacylation P 1 1 1 100 100 1 1 1 100 100 0.961 1 1 0004818 glutamate-tRNA ligase activity F 1 1 1 100 100 1 1 1 100 100 0.961 1 1 0008716 D-alanine-D-alanine ligase activity F 1 1 1 100 100 1 1 1 100 100 0.961 1 1 0008199 ferric iron binding F 1 1 1 100 100 1 1 1 100 100 0.961 1 1 0006879 cellular iron ion homeostasis P 1 1 1 100 100 1 1 1 100 100 0.961 1 1 0002943 tRNA dihydrouridine synthesis P 1 1 1 100 100 1 1 1 100 100 0.961 1 1 0016412 serine O-acyltransferase activity F 0 0 0 0 0 1 1 1 100 100 0.961 1 1 0044179 hemolysis in other organism P 1 1 1 100 100 1 1 1 100 100 0.961 1 1 0020002 host cell plasma membrane C 1 1 1 100 100 1 1 1 100 100 0.961 1 1 0030674 protein binding, bridging F 1 1 1 100 100 1 1 1 100 100 0.961 1 1 0033644 host cell membrane C 1 1 1 100 100 1 1 1 100 100 0.961 1 1 0032049 cardiolipin biosynthetic process P 1 1 1 100 100 1 1 1 100 100 0.961 1 1 0008808 cardiolipin synthase activity F 1 1 1 100 100 1 1 1 100 100 0.961 1 1 0019344 cysteine biosynthetic process P 0 0 1 0 0 1 1 2 100 50 0.961 1 1 0009070 serine family amino acid biosynthetic process P 0 0 0 0 0 1 1 5 100 20 0.961 1 1 0008784 alanine racemase activity F 1 1 1 100 100 1 1 1 100 100 0.961 1 1 0008897 holo-[acyl-carrier-protein] synthase activity F 1 1 1 100 100 1 1 1 100 100 0.961 1 1 0019357 nicotinate nucleotide biosynthetic process P 0 0 0 0 0 1 1 1 100 100 0.961 1 1 0015574 trehalose transmembrane transporter activity F 1 1 1 100 100 1 1 1 100 100 0.961 1 1 0008239 dipeptidyl-peptidase activity F 1 1 1 100 100 1 1 1 100 100 0.961 1 1 0006423 cysteinyl-tRNA aminoacylation P 1 1 1 100 100 1 1 1 100 100 0.961 1 1 0032048 cardiolipin metabolic process P 0 0 0 0 0 1 1 1 100 100 0.961 1 1 0006741 NADP biosynthetic process P 1 1 1 100 100 1 1 1 100 100 0.961 1 1 0015771 trehalose transport P 1 1 1 100 100 1 1 1 100 100 0.961 1 1 0004139 deoxyribose-phosphate aldolase activity F 1 1 1 100 100 1 1 1 100 100 0.961 1 1 0003954 NADH dehydrogenase activity F 1 1 1 100 100 1 1 1 100 100 0.961 1 1 0009264 deoxyribonucleotide catabolic process P 1 1 2 100 50 1 1 2 100 50 0.961 1 1 0004817 cysteine-tRNA ligase activity F 1 1 1 100 100 1 1 1 100 100 0.961 1 1 0046386 deoxyribose phosphate catabolic process P 1 1 1 100 100 1 1 1 100 100 0.961 1 1 0006522 alanine metabolic process P 1 1 1 100 100 1 1 1 100 100 0.961 1 1 0008961 phosphatidylglycerol-prolipoprotein diacylglyceryl transferase activity F 1 1 1 100 100 1 1 1 100 100 0.961 1 1 0009249 protein lipoylation P 1 1 2 100 50 1 1 2 100 50 0.961 1 1 0004788 thiamine diphosphokinase activity F 1 1 1 100 100 1 1 1 100 100 0.961 1 1 0046471 phosphatidylglycerol metabolic process P 0 0 0 0 0 1 1 1 100 100 0.961 1 1 0043086 negative regulation of catalytic activity P 1 1 1 100 100 1 1 1 100 100 0.961 1 1 0044087 regulation of cellular component biogenesis P 0 0 0 0 0 1 1 1 100 100 0.961 1 1 0042158 lipoprotein biosynthetic process P 1 1 1 100 100 1 1 1 100 100 0.961 1 1 0030632 D-alanine biosynthetic process P 1 1 1 100 100 1 1 1 100 100 0.961 1 1 0009446 putrescine biosynthetic process P 1 1 1 100 100 1 1 1 100 100 0.961 1 1 0006275 regulation of DNA replication P 1 1 1 100 100 1 1 1 100 100 0.961 1 1 0004515 nicotinate-nucleotide adenylyltransferase activity F 1 1 1 100 100 1 1 1 100 100 0.961 1 1 0004314 [acyl-carrier-protein] S-malonyltransferase activity F 1 1 1 100 100 1 1 1 100 100 0.961 1 1 0003922 GMP synthase (glutamine-hydrolyzing) activity F 1 1 1 100 100 1 1 1 100 100 0.961 1 1 0006270 DNA replication initiation P 1 1 1 100 100 1 1 1 100 100 0.961 1 1 0003688 DNA replication origin binding F 1 1 1 100 100 1 1 1 100 100 0.961 1 1 0004668 protein-arginine deiminase activity F 1 1 1 100 100 1 1 1 100 100 0.961 1 1 0022618 ribonucleoprotein complex assembly P 0 0 0 0 0 1 1 1 100 100 0.961 1 1 0047632 agmatine deiminase activity F 1 1 1 100 100 1 1 1 100 100 0.961 1 1 0004514 nicotinate-nucleotide diphosphorylase (carboxylating) activity F 1 1 2 100 50 1 1 2 100 50 0.961 1 1 0015203 polyamine transmembrane transporter activity F 0 0 0 0 0 1 1 1 100 100 0.961 1 1 0043094 cellular metabolic compound salvage P 0 0 1 0 0 2 3 9 66.66666 33.33333 0.509 1 1 0010181 FMN binding F 2 3 4 66.66666 75 2 3 4 66.66666 75 0.509 1 1 0009360 DNA polymerase III complex C 2 3 3 66.66666 100 2 3 3 66.66666 100 0.509 1 1 0016311 dephosphorylation P 0 1 1 0 100 2 3 3 66.66666 100 0.509 1 1 0070475 rRNA base methylation P 1 2 2 50 100 2 3 3 66.66666 100 0.509 1 1 0061505 DNA topoisomerase II activity F 0 0 0 0 0 2 3 4 66.66666 75 0.509 1 1 0016778 diphosphotransferase activity F 0 0 0 0 0 2 3 5 66.66666 60 0.509 1 1 1990204 oxidoreductase complex C 0 0 0 0 0 2 3 4 66.66666 75 0.509 1 1 0016668 oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor F 1 2 3 50 66.66666 2 3 4 66.66666 75 0.509 1 1 0043173 nucleotide salvage P 0 0 0 0 0 2 3 7 66.66666 42.85714 0.509 1 1 0032508 DNA duplex unwinding P 1 2 2 50 100 2 3 3 66.66666 100 0.509 1 1 0015114 phosphate ion transmembrane transporter activity F 0 0 0 0 0 2 3 4 66.66666 75 0.509 1 1 0016895 exodeoxyribonuclease activity, producing 5’-phosphomonoesters F 0 0 0 0 0 2 3 3 66.66666 100 0.509 1 1 0003918 DNA topoisomerase type II (ATP-hydrolyzing) activity F 2 3 4 66.66666 75 2 3 4 66.66666 75 0.509 1 1 0016209 antioxidant activity F 1 2 2 50 100 2 3 6 66.66666 50 0.509 1 1 0032392 DNA geometric change P 0 0 0 0 0 2 3 3 66.66666 100 0.509 1 1 0016776 phosphotransferase activity, phosphate group as acceptor F 0 1 1 0 100 2 3 6 66.66666 50 0.509 1 1 0009055 electron carrier activity F 2 3 4 66.66666 75 2 3 4 66.66666 75 0.509 1 1 0042575 DNA polymerase complex C 0 0 0 0 0 2 3 3 66.66666 100 0.509 1 1 0035435 phosphate ion transmembrane transport P 2 3 5 66.66666 60 2 3 6 66.66666 50 0.509 1 1 0004529 exodeoxyribonuclease activity F 0 0 0 0 0 2 3 3 66.66666 100 0.509 1 1 0019692 deoxyribose phosphate metabolic process P 0 0 0 0 0 2 3 4 66.66666 75 0.509 1 1 0016811 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides F 0 0 0 0 0 2 3 7 66.66666 42.85714 0.509 1 1 0070566 adenylyltransferase activity F 0 0 0 0 0 2 3 5 66.66666 60 0.509 1 1 0006450 regulation of translational fidelity P 3 5 6 60 83.33334 3 5 6 60 83.33334 0.358 1 1 0052689 carboxylic ester hydrolase activity F 0 0 0 0 0 3 5 7 60 71.42857 0.358 1 1 0006448 regulation of translational elongation P 0 0 0 0 0 3 5 6 60 83.33334 0.358 1 1 0046873 metal ion transmembrane transporter activity F 2 2 2 100 100 3 5 6 60 83.33334 0.358 1 1 0031226 intrinsic to plasma membrane C 1 1 1 100 100 3 5 7 60 71.42857 0.358 1 1 0005315 inorganic phosphate transmembrane transporter activity F 3 5 7 60 71.42857 3 5 7 60 71.42857 0.358 1 1 0016893 endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5’-phosphomonoesters F 0 0 0 0 0 3 5 10 60 50 0.358 1 1 0008026 ATP-dependent helicase activity F 2 3 7 66.66666 42.85714 3 5 9 60 55.55556 0.358 1 1 0042886 amide transport P 0 0 0 0 0 3 5 9 60 55.55556 0.358 1 1 0034030 ribonucleoside bisphosphate biosynthetic process P 0 0 0 0 0 3 5 5 60 100 0.358 1 1 0016796 exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5’-phosphomonoesters F 0 0 0 0 0 3 5 5 60 100 0.358 1 1 0006525 arginine metabolic process P 2 3 6 66.66666 50 3 5 9 60 55.55556 0.358 1 1 0008649 rRNA methyltransferase activity F 2 3 3 66.66666 100 3 5 5 60 100 0.358 1 1 1901677 phosphate transmembrane transporter activity F 0 0 0 0 0 3 5 7 60 71.42857 0.358 1 1 0015937 coenzyme A biosynthetic process P 2 3 3 66.66666 100 3 5 5 60 100 0.358 1 1 0033866 nucleoside bisphosphate biosynthetic process P 0 0 0 0 0 3 5 5 60 100 0.358 1 1 0019877 diaminopimelate biosynthetic process P 3 5 5 60 100 3 5 5 60 100 0.358 1 1 0008094 DNA-dependent ATPase activity F 0 0 1 0 0 3 5 8 60 62.5 0.358 1 1 0015936 coenzyme A metabolic process P 0 0 1 0 0 3 5 6 60 83.33334 0.358 1 1 0070035 purine NTP-dependent helicase activity F 0 0 0 0 0 3 5 9 60 55.55556 0.358 1 1 0034033 purine nucleoside bisphosphate biosynthetic process P 0 0 0 0 0 3 5 5 60 100 0.358 1 1 0009308 amine metabolic process P 1 1 1 100 100 4 7 10 57.14286 70 0.273 1 1 0044769 ATPase activity, coupled to transmembrane movement of ions, rotational mechanism F 0 0 0 0 0 4 7 10 57.14286 70 0.273 1 1 0017171 serine hydrolase activity F 0 0 0 0 0 4 7 11 57.14286 63.63636 0.273 1 1 0046933 proton-transporting ATP synthase activity, rotational mechanism F 4 7 10 57.14286 70 4 7 10 57.14286 70 0.273 1 1 0008236 serine-type peptidase activity F 1 2 4 50 50 4 7 11 57.14286 63.63636 0.273 1 1 0042777 plasma membrane ATP synthesis coupled proton transport P 4 7 10 57.14286 70 4 7 10 57.14286 70 0.273 1 1 0016903 oxidoreductase activity, acting on the aldehyde or oxo group of donors F 0 0 0 0 0 4 7 8 57.14286 87.5 0.273 1 1 0016836 hydro-lyase activity F 1 1 1 100 100 4 7 10 57.14286 70 0.273 1 1 0070271 protein complex biogenesis P 0 0 0 0 0 4 7 9 57.14286 77.77778 0.273 1 1 0006461 protein complex assembly P 0 0 0 0 0 4 7 9 57.14286 77.77778 0.273 1 1 0016469 proton-transporting two-sector ATPase complex C 0 0 0 0 0 5 9 12 55.55556 75 0.214 1 1 0016857 racemase and epimerase activity, acting on carbohydrates and derivatives F 2 3 3 66.66666 100 5 9 12 55.55556 75 0.214 1 1 0009057 macromolecule catabolic process P 0 0 0 0 0 6 11 14 54.54546 78.57143 0.169 1 1 0043234 protein complex C 1 1 1 100 100 16 30 37 53.33333 81.08108 0.147 1 1 0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor F 4 5 7 80 71.42857 7 13 19 53.84615 68.42105 0.133 1 1 0005576 extracellular region C 7 13 18 53.84615 72.22222 7 13 18 53.84615 72.22222 0.133 1 1 0008168 methyltransferase activity F 15 29 38 51.72414 76.31579 17 32 41 53.125 78.04878 0.128 1 1 0016614 oxidoreductase activity, acting on CH-OH group of donors F 2 3 3 66.66666 100 8 15 21 53.33333 71.42857 0.103 1 1 0043412 macromolecule modification P 0 0 0 0 0 31 59 75 52.54237 78.66666 0.084 1 1 0009119 ribonucleoside metabolic process P 0 0 0 0 0 55 105 139 52.38095 75.53957 0.08 1 1 0004519 endonuclease activity F 8 13 22 61.53846 59.09091 9 17 27 52.94118 62.96296 0.077 1 1 0043414 macromolecule methylation P 0 0 0 0 0 10 19 22 52.63158 86.36364 0.055 1 1 0003824 catalytic activity F 78 141 205 55.31915 68.78049 341 655 915 52.06107 71.5847 0.042 1 1 GO Gene Ontology r 0 0 0 0 0 543 1044 1473 52.01149 70.87576 0 1 1 0016407 acetyltransferase activity F 1 3 3 33.33333 100 13 25 32 52 78.125 -0.001 1 1 0006508 proteolysis P 14 27 41 51.85185 65.85366 14 27 41 51.85185 65.85366 -0.017 1 1 0051716 cellular response to stimulus P 0 0 0 0 0 30 58 76 51.72414 76.31579 -0.045 1 1 0032259 methylation P 15 29 38 51.72414 76.31579 16 31 40 51.6129 77.5 -0.045 1 1 0070567 cytidylyltransferase activity F 0 0 0 0 0 1 2 3 50 66.66666 -0.057 1 1 0046416 D-amino acid metabolic process P 0 0 0 0 0 1 2 2 50 100 -0.057 1 1 0019842 vitamin binding F 0 0 0 0 0 1 2 2 50 100 -0.057 1 1 0044445 cytosolic part C 0 0 0 0 0 1 2 3 50 66.66666 -0.057 1 1 0008855 exodeoxyribonuclease VII activity F 1 2 2 50 100 1 2 2 50 100 -0.057 1 1 0006144 purine nucleobase metabolic process P 0 0 0 0 0 1 2 5 50 40 -0.057 1 1 0015846 polyamine transport P 1 2 2 50 100 1 2 2 50 100 -0.057 1 1 0006206 pyrimidine nucleobase metabolic process P 0 1 1 0 100 1 2 7 50 28.57143 -0.057 1 1 0005186 pheromone activity F 1 2 3 50 66.66666 1 2 3 50 66.66666 -0.057 1 1 0043225 anion transmembrane-transporting ATPase activity F 0 0 0 0 0 1 2 3 50 66.66666 -0.057 1 1 0006298 mismatch repair P 1 2 3 50 66.66666 1 2 3 50 66.66666 -0.057 1 1 0046116 queuosine metabolic process P 0 0 0 0 0 1 2 3 50 66.66666 -0.057 1 1 0030983 mismatched DNA binding F 1 2 3 50 66.66666 1 2 3 50 66.66666 -0.057 1 1 0004565 beta-galactosidase activity F 1 2 2 50 100 1 2 2 50 100 -0.057 1 1 0046112 nucleobase biosynthetic process P 0 0 0 0 0 1 2 8 50 25 -0.057 1 1 0016684 oxidoreductase activity, acting on peroxide as acceptor F 0 1 1 0 100 1 2 3 50 66.66666 -0.057 1 1 0016433 rRNA (adenine) methyltransferase activity F 0 1 1 0 100 1 2 2 50 100 -0.057 1 1 0009009 site-specific recombinase activity F 0 0 0 0 0 1 2 2 50 100 -0.057 1 1 0009318 exodeoxyribonuclease VII complex C 1 2 2 50 100 1 2 2 50 100 -0.057 1 1 0008616 queuosine biosynthetic process P 1 2 3 50 66.66666 1 2 3 50 66.66666 -0.057 1 1 0017038 protein import P 1 2 2 50 100 1 2 2 50 100 -0.057 1 1 0046939 nucleotide phosphorylation P 0 1 1 0 100 1 2 2 50 100 -0.057 1 1 0019201 nucleotide kinase activity F 0 1 1 0 100 1 2 5 50 40 -0.057 1 1 0044210 ’de novo’ CTP biosynthetic process P 1 2 2 50 100 1 2 2 50 100 -0.057 1 1 0006595 polyamine metabolic process P 0 0 0 0 0 1 2 3 50 66.66666 -0.057 1 1 0016896 exoribonuclease activity, producing 5’-phosphomonoesters F 0 0 0 0 0 1 2 2 50 100 -0.057 1 1 0030976 thiamine pyrophosphate binding F 1 2 2 50 100 1 2 2 50 100 -0.057 1 1 0004834 tryptophan synthase activity F 1 2 2 50 100 1 2 2 50 100 -0.057 1 1 0008907 integrase activity F 0 0 0 0 0 1 2 2 50 100 -0.057 1 1 0006308 DNA catabolic process P 1 2 2 50 100 1 2 2 50 100 -0.057 1 1 0015197 peptide transporter activity F 1 1 1 100 100 1 2 2 50 100 -0.057 1 1 0051262 protein tetramerization P 1 2 2 50 100 1 2 2 50 100 -0.057 1 1 0005102 receptor binding F 0 0 0 0 0 1 2 3 50 66.66666 -0.057 1 1 0016813 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines F 0 1 1 0 100 1 2 2 50 100 -0.057 1 1 0035999 tetrahydrofolate interconversion P 1 2 3 50 66.66666 1 2 3 50 66.66666 -0.057 1 1 0009037 tyrosine-based site-specific recombinase activity F 1 2 2 50 100 1 2 2 50 100 -0.057 1 1 0006167 AMP biosynthetic process P 0 0 0 0 0 1 2 3 50 66.66666 -0.057 1 1 0046033 AMP metabolic process P 0 0 0 0 0 1 2 3 50 66.66666 -0.057 1 1 0003984 acetolactate synthase activity F 1 2 2 50 100 1 2 2 50 100 -0.057 1 1 0004601 peroxidase activity F 1 2 3 50 66.66666 1 2 3 50 66.66666 -0.057 1 1 0003989 acetyl-CoA carboxylase activity F 1 2 4 50 50 1 2 4 50 50 -0.057 1 1 0006596 polyamine biosynthetic process P 0 1 2 0 50 1 2 3 50 66.66666 -0.057 1 1 0033013 tetrapyrrole metabolic process P 0 0 0 0 0 1 2 3 50 66.66666 -0.057 1 1 0050567 glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity F 1 2 2 50 100 1 2 2 50 100 -0.057 1 1 0030488 tRNA methylation P 1 2 2 50 100 1 2 2 50 100 -0.057 1 1 0015154 disaccharide transmembrane transporter activity F 0 0 0 0 0 1 2 2 50 100 -0.057 1 1 0016755 transferase activity, transferring amino-acyl groups F 1 2 2 50 100 1 2 2 50 100 -0.057 1 1 0009200 deoxyribonucleoside triphosphate metabolic process P 0 0 0 0 0 1 2 3 50 66.66666 -0.057 1 1 2001293 malonyl-CoA metabolic process P 0 0 0 0 0 1 2 2 50 100 -0.057 1 1 0042802 identical protein binding F 1 2 5 50 40 1 2 7 50 28.57143 -0.057 1 1 0055129 L-proline biosynthetic process P 1 2 2 50 100 1 2 2 50 100 -0.057 1 1 0016885 ligase activity, forming carbon-carbon bonds F 0 0 0 0 0 1 2 4 50 50 -0.057 1 1 0051920 peroxiredoxin activity F 1 1 1 100 100 1 2 2 50 100 -0.057 1 1 0016408 C-acyltransferase activity F 0 0 0 0 0 1 2 2 50 100 -0.057 1 1 0042822 pyridoxal phosphate metabolic process P 0 0 0 0 0 1 2 2 50 100 -0.057 1 1 0003934 GTP cyclohydrolase I activity F 1 2 2 50 100 1 2 2 50 100 -0.057 1 1 0000725 recombinational repair P 0 0 0 0 0 1 2 2 50 100 -0.057 1 1 0004003 ATP-dependent DNA helicase activity F 1 2 3 50 66.66666 1 2 3 50 66.66666 -0.057 1 1 0006302 double-strand break repair P 0 1 1 0 100 1 2 2 50 100 -0.057 1 1 0003933 GTP cyclohydrolase activity F 0 0 0 0 0 1 2 3 50 66.66666 -0.057 1 1 0006779 porphyrin-containing compound biosynthetic process P 1 2 2 50 100 1 2 2 50 100 -0.057 1 1 0051066 dihydrobiopterin metabolic process P 0 0 0 0 0 1 2 2 50 100 -0.057 1 1 0009219 pyrimidine deoxyribonucleotide metabolic process P 0 0 0 0 0 1 2 3 50 66.66666 -0.057 1 1 0033014 tetrapyrrole biosynthetic process P 0 0 0 0 0 1 2 3 50 66.66666 -0.057 1 1 0016453 C-acetyltransferase activity F 0 0 0 0 0 1 2 2 50 100 -0.057 1 1 0016417 S-acyltransferase activity F 0 0 0 0 0 1 2 2 50 100 -0.057 1 1 0042823 pyridoxal phosphate biosynthetic process P 1 2 2 50 100 1 2 2 50 100 -0.057 1 1 0008861 formate C-acetyltransferase activity F 1 2 2 50 100 1 2 2 50 100 -0.057 1 1 0016805 dipeptidase activity F 1 2 3 50 66.66666 1 2 3 50 66.66666 -0.057 1 1 0009380 excinuclease repair complex C 1 2 2 50 100 1 2 2 50 100 -0.057 1 1 0009331 glycerol-3-phosphate dehydrogenase complex C 1 2 2 50 100 1 2 2 50 100 -0.057 1 1 0051052 regulation of DNA metabolic process P 0 0 0 0 0 1 2 2 50 100 -0.057 1 1 0006778 porphyrin-containing compound metabolic process P 0 0 0 0 0 1 2 2 50 100 -0.057 1 1 2001295 malonyl-CoA biosynthetic process P 1 2 2 50 100 1 2 2 50 100 -0.057 1 1 0009317 acetyl-CoA carboxylase complex C 1 2 3 50 66.66666 1 2 3 50 66.66666 -0.057 1 1 0000988 protein binding transcription factor activity F 0 0 0 0 0 1 2 4 50 50 -0.057 1 1 0004143 diacylglycerol kinase activity F 1 2 2 50 100 1 2 2 50 100 -0.057 1 1 0016841 ammonia-lyase activity F 0 0 0 0 0 1 2 3 50 66.66666 -0.057 1 1 0015772 oligosaccharide transport P 0 0 0 0 0 1 2 2 50 100 -0.057 1 1 0009065 glutamine family amino acid catabolic process P 0 0 0 0 0 1 2 4 50 50 -0.057 1 1 0003896 DNA primase activity F 1 2 2 50 100 1 2 2 50 100 -0.057 1 1 0015766 disaccharide transport P 0 0 0 0 0 1 2 2 50 100 -0.057 1 1 0006269 DNA replication, synthesis of RNA primer P 1 2 2 50 100 1 2 2 50 100 -0.057 1 1 0016624 oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor F 1 1 1 100 100 1 2 2 50 100 -0.057 1 1 0015415 phosphate ion transmembrane-transporting ATPase activity F 1 2 3 50 66.66666 1 2 3 50 66.66666 -0.057 1 1 0008171 O-methyltransferase activity F 0 1 1 0 100 1 2 2 50 100 -0.057 1 1 0015157 oligosaccharide transmembrane transporter activity F 0 0 0 0 0 1 2 2 50 100 -0.057 1 1 0016421 CoA carboxylase activity F 0 0 0 0 0 1 2 4 50 50 -0.057 1 1 0003951 NAD+ kinase activity F 1 2 2 50 100 1 2 2 50 100 -0.057 1 1 0004532 exoribonuclease activity F 0 0 0 0 0 1 2 2 50 100 -0.057 1 1 0009211 pyrimidine deoxyribonucleoside triphosphate metabolic process P 0 0 0 0 0 1 2 3 50 66.66666 -0.057 1 1 0004396 hexokinase activity F 0 0 0 0 0 1 2 2 50 100 -0.057 1 1 0000724 double-strand break repair via homologous recombination P 1 2 2 50 100 1 2 2 50 100 -0.057 1 1 0009394 2’-deoxyribonucleotide metabolic process P 0 0 0 0 0 1 2 3 50 66.66666 -0.057 1 1 0035998 7,8-dihydroneopterin 3’-triphosphate biosynthetic process P 1 2 2 50 100 1 2 2 50 100 -0.057 1 1 0016741 transferase activity, transferring one-carbon groups F 0 0 0 0 0 17 33 46 51.51515 71.73913 -0.058 1 1 0042623 ATPase activity, coupled F 0 0 0 0 0 18 35 50 51.42857 70 -0.07 1 1 0003678 DNA helicase activity F 1 2 2 50 100 2 4 6 50 66.66666 -0.081 1 1 0006289 nucleotide-excision repair P 2 4 4 50 100 2 4 4 50 100 -0.081 1 1 0003690 double-stranded DNA binding F 1 2 2 50 100 2 4 5 50 80 -0.081 1 1 0009112 nucleobase metabolic process P 0 0 0 0 0 2 4 12 50 33.33333 -0.081 1 1 0070569 uridylyltransferase activity F 0 0 0 0 0 2 4 4 50 100 -0.081 1 1 0008565 protein transporter activity F 0 0 1 0 0 2 4 5 50 80 -0.081 1 1 0022402 cell cycle process P 0 0 0 0 0 2 4 10 50 40 -0.081 1 1 0006568 tryptophan metabolic process P 2 3 4 66.66666 75 2 4 6 50 66.66666 -0.081 1 1 0015450 P-P-bond-hydrolysis-driven protein transmembrane transporter activity F 2 3 3 66.66666 100 2 4 4 50 100 -0.081 1 1 0022884 macromolecule transmembrane transporter activity F 0 0 0 0 0 2 4 4 50 100 -0.081 1 1 0046219 indolalkylamine biosynthetic process P 0 0 0 0 0 2 4 6 50 66.66666 -0.081 1 1 0003684 damaged DNA binding F 2 4 5 50 80 2 4 5 50 80 -0.081 1 1 0016620 oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor F 2 4 5 50 80 2 4 5 50 80 -0.081 1 1 0042493 response to drug P 0 0 0 0 0 2 4 4 50 100 -0.081 1 1 0034622 cellular macromolecular complex assembly P 0 0 0 0 0 2 4 5 50 80 -0.081 1 1 0042435 indole-containing compound biosynthetic process P 0 0 0 0 0 2 4 6 50 66.66666 -0.081 1 1 0003978 UDP-glucose 4-epimerase activity F 2 4 4 50 100 2 4 4 50 100 -0.081 1 1 0006586 indolalkylamine metabolic process P 0 0 0 0 0 2 4 6 50 66.66666 -0.081 1 1 0016840 carbon-nitrogen lyase activity F 0 0 0 0 0 2 4 5 50 80 -0.081 1 1 0000162 tryptophan biosynthetic process P 2 4 6 50 66.66666 2 4 6 50 66.66666 -0.081 1 1 0042430 indole-containing compound metabolic process P 0 0 0 0 0 2 4 6 50 66.66666 -0.081 1 1 0008320 protein transmembrane transporter activity F 0 0 0 0 0 2 4 4 50 100 -0.081 1 1 0005887 integral to plasma membrane C 2 4 6 50 66.66666 2 4 6 50 66.66666 -0.081 1 1 0015893 drug transport P 0 0 0 0 0 2 4 4 50 100 -0.081 1 1 0000154 rRNA modification P 0 1 1 0 100 3 6 7 50 85.71429 -0.099 1 1 0042401 cellular biogenic amine biosynthetic process P 0 0 0 0 0 3 6 9 50 66.66666 -0.099 1 1 0009309 amine biosynthetic process P 0 0 0 0 0 3 6 9 50 66.66666 -0.099 1 1 0004252 serine-type endopeptidase activity F 3 6 8 50 75 3 6 8 50 75 -0.099 1 1 0016651 oxidoreductase activity, acting on NAD(P)H F 0 0 0 0 0 3 6 7 50 85.71429 -0.099 1 1 0044106 cellular amine metabolic process P 0 0 0 0 0 3 6 9 50 66.66666 -0.099 1 1 0031167 rRNA methylation P 2 4 5 50 80 3 6 7 50 85.71429 -0.099 1 1 0001522 pseudouridine synthesis P 3 6 8 50 75 3 6 8 50 75 -0.099 1 1 0009982 pseudouridine synthase activity F 3 6 8 50 75 3 6 8 50 75 -0.099 1 1 0009405 pathogenesis P 3 6 9 50 66.66666 3 6 9 50 66.66666 -0.099 1 1 0051082 unfolded protein binding F 3 6 7 50 85.71429 3 6 7 50 85.71429 -0.099 1 1 0018193 peptidyl-amino acid modification P 0 0 0 0 0 3 6 8 50 75 -0.099 1 1 0006576 cellular biogenic amine metabolic process P 0 0 0 0 0 3 6 9 50 66.66666 -0.099 1 1 0009110 vitamin biosynthetic process P 0 0 0 0 0 4 8 16 50 50 -0.114 1 1 0042364 water-soluble vitamin biosynthetic process P 0 0 0 0 0 4 8 16 50 50 -0.114 1 1 0015992 proton transport P 5 8 11 62.5 72.72727 5 10 13 50 76.92308 -0.128 1 1 0030420 establishment of competence for transformation P 5 10 10 50 100 5 10 10 50 100 -0.128 1 1 0006818 hydrogen transport P 0 0 0 0 0 5 10 13 50 76.92308 -0.128 1 1 0006767 water-soluble vitamin metabolic process P 0 0 0 0 0 5 10 18 50 55.55556 -0.128 1 1 0006766 vitamin metabolic process P 0 0 0 0 0 5 10 18 50 55.55556 -0.128 1 1 0004222 metalloendopeptidase activity F 5 10 15 50 66.66666 5 10 15 50 66.66666 -0.128 1 1 0001510 RNA methylation P 2 5 5 40 100 6 12 13 50 92.30769 -0.14 1 1 0022890 inorganic cation transmembrane transporter activity F 0 0 0 0 0 8 16 20 50 80 -0.162 1 1 0044262 cellular carbohydrate metabolic process P 1 1 1 100 100 11 22 31 50 70.96774 -0.191 1 1