The easiest websites to use were SGD and UniProt due to their presentation. SGD has a lot of information on ACT1, and it can be accessed quickly by the different tabs on the gene’s page. UniProt identifies information easily through a good use of color and spacing. It was hard to find information on Ensembl, and the ACT1 information that was on the website was minimal (simple things like description, synonyms, etc). NCBI looks as if it has not been updated in 15 years. The website has a sufficient amount of information, but it wasn’t pleasant to navigate. It does, however, have a lot of links to external for more information regarding ACT1.

Across all platforms, the data that we looked through was the same. In other terms, some websites had more information, but the general information was consistent.

ATGGATTCTG AGGTTGCTGC TTTGGTTATT GATAACGGTT CTGGTATGTG TAAAGCCGGT
TTTGCCGGTG ACGACGCTCC TCGTGCTGTC TTCCCATCTA TCGTCGGTAG ACCAAGACAC
CAAGGTATCA TGGTCGGTAT GGGTCAAAAA GACTCCTACG TTGGTGATGA AGCTCAATCC
AAGAGAGGTA TCTTGACTTT ACGTTACCCA ATTGAACACG GTATTGTCAC CAACTGGGAC
GATATGGAAA AGATCTGGCA TCATACCTTC TACAACGAAT TGAGAGTTGC CCCAGAAGAA
CACCCTGTTC TTTTGACTGA AGCTCCAATG AACCCTAAAT CAAACAGAGA AAAGATGACT
CAAATTATGT TTGAAACTTT CAACGTTCCA GCCTTCTACG TTTCCATCCA AGCCGTTTTG
TCCTTGTACT CTTCCGGTAG AACTACTGGT ATTGTTTTGG ATTCCGGTGA TGGTGTTACT
CACGTCGTTC CAATTTACGC TGGTTTCTCT CTACCTCACG CCATTTTGAG AATCGATTTG
GCCGGTAGAG ATTTGACTGA CTACTTGATG AAGATCTTGA GTGAACGTGG TTACTCTTTC
TCCACCACTG CTGAAAGAGA AATTGTCCGT GACATCAAGG AAAAACTATG TTACGTCGCC
TTGGACTTCG AACAAGAAAT GCAAACCGCT GCTCAATCTT CTTCAATTGA AAAATCCTAC
GAACTTCCAG ATGGTCAAGT CATCACTATT GGTAACGAAA GATTCAGAGC CCCAGAAGCT
TTGTTCCATC CTTCTGTTTT GGGTTTGGAA TCTGCCGGTA TTGACCAAAC TACTTACAAC
TCCATCATGA AGTGTGATGT CGATGTCCGT AAGGAATTAT ACGGTAACAT CGTTATGTCC
GGTGGTACCA CCATGTTCCC AGGTATTGCC GAAAGAATGC AAAAGGAAAT CACCGCTTTG
GCTCCATCTT CCATGAAGGT CAAGATCATT GCTCCTCCAG AAAGAAAGTA CTCCGTCTGG
ATTGGTGGTT CTATCTTGGC TTCTTTGACT ACCTTCCAAC AAATGTGGAT CTCAAAACAA
GAATACGACG AAAGTGGTCC ATCTATCGTT CACCACAAGT GTTTCTAA

Derived from laboratory strain S288C

MDSEVAALVI DNGSGMCKAG FAGDDAPRAV FPSIVGRPRH QGIMVGMGQK DSYVGDEAQS
KRGILTLRYP IEHGIVTNWD DMEKIWHHTF YNELRVAPEE HPVLLTEAPM NPKSNREKMT
QIMFETFNVP AFYVSIQAVL SLYSSGRTTG IVLDSGDGVT HVVPIYAGFS LPHAILRIDL
AGRDLTDYLM KILSERGYSF STTAEREIVR DIKEKLCYVA LDFEQEMQTA AQSSSIEKSY
ELPDGQVITI GNERFRAPEA LFHPSVLGLE SAGIDQTTYN SIMKCDVDVR KELYGNIVMS
GGTTMFPGIA ERMQKEITAL APSSMKVKII APPERKYSVW IGGSILASLT TFQQMWISKQ
EYDESGPSIV HHKCF*

Derived from laboratory strain S288C

ACT1 encodes the single essential gene for actin, which is a structural protein expressed in all eukaryotic cells. It is involved in cytoskeletal functions such as cell polarization and endocytosis.

To be completely honest, ACT1 is the gene we were introduced to in the demonstration in class. Yet, we found it interesting that ACT1 is a structural protein.

This diagram displays domains shared between ACT1 and other proteins

Acknowledgements:
Professor Dionisio for his demonstration in class and also some help with the website on the side.
Professor Dahlquist for her demonstration in class.

References:
ACT1. (n.d.). Retrieved October 16, 2017, from
    https://www.yeastgenome.org/locus/S000001855
ACT1 actin [Saccharomyces cerevisiae S288C] - Gene - NCBI. (n.d.). Retrieved October 16, 2017, from
    https://www.ncbi.nlm.nih.gov/gene/850504
European Bioinformatics Institute Protein Information Resource SIB. (2017, September 27). Actin.
    Retrieved October 16, 2017, from http://www.uniprot.org/uniprot/P60010
Gene 'YFL039C;r'. (n.d.). Retrieved October 16, 2017, from
    https://www.ensembl.org/Saccharomyces_cerevisiae/Gene/Compara_Tree?g=YFL039C
Week 4. (n.d.). Retrieved October 16, 2017, from
    https://xmlpipedb.cs.lmu.edu/biodb/fall2017/index.php/Week_4
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    https://api.jquery.com/jQuery.get/
Jquery.org, J. F. (n.d.). JQuery.getJSON(). Retrieved October 16, 2017, from
    https://api.jquery.com/jQuery.getJSON/
Week 7. (n.d.). Retrieved October 16, 2017, from
    https://xmlpipedb.cs.lmu.edu/biodb/fall2017/index.php/Week_7
Mark Otto, Jacob Thornton, and Bootstrap contributors. (n.d.). Bootstrap. Retrieved October 16, 2017 from
    http://getbootstrap.com/